Machine Learning And Network Driven Integrative Genomics

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Machine Learning and Network-Driven Integrative Genomics

Author : Mehdi Pirooznia,Richard S. Lee,Shizhong Han
Publisher : Frontiers Media SA
Page : 143 pages
File Size : 55,7 Mb
Release : 2021-04-29
Category : Science
ISBN : 9782889667253

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Machine Learning and Network-Driven Integrative Genomics by Mehdi Pirooznia,Richard S. Lee,Shizhong Han Pdf

Big Data Analytics in Genomics

Author : Ka-Chun Wong
Publisher : Springer
Page : 428 pages
File Size : 46,8 Mb
Release : 2016-10-24
Category : Computers
ISBN : 9783319412795

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Big Data Analytics in Genomics by Ka-Chun Wong Pdf

This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or veterans in the field.This volume offers thirteen peer-reviewed contributions, written by international leading experts from different regions, representing Argentina, Brazil, China, France, Germany, Hong Kong, India, Japan, Spain, and the USA. In particular, the book surveys three main areas: statistical analytics, computational analytics, and cancer genome analytics. Sample topics covered include: statistical methods for integrative analysis of genomic data, computation methods for protein function prediction, and perspectives on machine learning techniques in big data mining of cancer. Self-contained and suitable for graduate students, this book is also designed for bioinformaticians, computational biologists, and researchers in communities ranging from genomics, big data, molecular genetics, data mining, biostatistics, biomedical science, cancer research, medical research, and biology to machine learning and computer science. Readers will find this volume to be an essential read for appreciating the role of big data in genomics, making this an invaluable resource for stimulating further research on the topic.

Deep Learning for Genomics

Author : Upendra Kumar Devisetty
Publisher : Packt Publishing Ltd
Page : 270 pages
File Size : 42,7 Mb
Release : 2022-11-11
Category : Computers
ISBN : 9781804613016

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Deep Learning for Genomics by Upendra Kumar Devisetty Pdf

Learn concepts, methodologies, and applications of deep learning for building predictive models from complex genomics data sets to overcome challenges in the life sciences and biotechnology industries Key FeaturesApply deep learning algorithms to solve real-world problems in the field of genomicsExtract biological insights from deep learning models built from genomic datasetsTrain, tune, evaluate, deploy, and monitor deep learning models for enabling predictions in genomicsBook Description Deep learning has shown remarkable promise in the field of genomics; however, there is a lack of a skilled deep learning workforce in this discipline. This book will help researchers and data scientists to stand out from the rest of the crowd and solve real-world problems in genomics by developing the necessary skill set. Starting with an introduction to the essential concepts, this book highlights the power of deep learning in handling big data in genomics. First, you'll learn about conventional genomics analysis, then transition to state-of-the-art machine learning-based genomics applications, and finally dive into deep learning approaches for genomics. The book covers all of the important deep learning algorithms commonly used by the research community and goes into the details of what they are, how they work, and their practical applications in genomics. The book dedicates an entire section to operationalizing deep learning models, which will provide the necessary hands-on tutorials for researchers and any deep learning practitioners to build, tune, interpret, deploy, evaluate, and monitor deep learning models from genomics big data sets. By the end of this book, you'll have learned about the challenges, best practices, and pitfalls of deep learning for genomics. What you will learnDiscover the machine learning applications for genomicsExplore deep learning concepts and methodologies for genomics applicationsUnderstand supervised deep learning algorithms for genomics applicationsGet to grips with unsupervised deep learning with autoencodersImprove deep learning models using generative modelsOperationalize deep learning models from genomics datasetsVisualize and interpret deep learning modelsUnderstand deep learning challenges, pitfalls, and best practicesWho this book is for This deep learning book is for machine learning engineers, data scientists, and academicians practicing in the field of genomics. It assumes that readers have intermediate Python programming knowledge, basic knowledge of Python libraries such as NumPy and Pandas to manipulate and parse data, Matplotlib, and Seaborn for visualizing data, along with a base in genomics and genomic analysis concepts.

Handbook of Machine Learning Applications for Genomics

Author : Sanjiban Sekhar Roy,Y.-H. Taguchi
Publisher : Springer Nature
Page : 222 pages
File Size : 46,6 Mb
Release : 2022-06-23
Category : Technology & Engineering
ISBN : 9789811691584

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Handbook of Machine Learning Applications for Genomics by Sanjiban Sekhar Roy,Y.-H. Taguchi Pdf

Currently, machine learning is playing a pivotal role in the progress of genomics. The applications of machine learning are helping all to understand the emerging trends and the future scope of genomics. This book provides comprehensive coverage of machine learning applications such as DNN, CNN, and RNN, for predicting the sequence of DNA and RNA binding proteins, expression of the gene, and splicing control. In addition, the book addresses the effect of multiomics data analysis of cancers using tensor decomposition, machine learning techniques for protein engineering, CNN applications on genomics, challenges of long noncoding RNAs in human disease diagnosis, and how machine learning can be used as a tool to shape the future of medicine. More importantly, it gives a comparative analysis and validates the outcomes of machine learning methods on genomic data to the functional laboratory tests or by formal clinical assessment. The topics of this book will cater interest to academicians, practitioners working in the field of functional genomics, and machine learning. Also, this book shall guide comprehensively the graduate, postgraduates, and Ph.D. scholars working in these fields.

Machine Learning and Systems Biology in Genomics and Health

Author : Shailza Singh
Publisher : Springer Nature
Page : 239 pages
File Size : 53,7 Mb
Release : 2022-02-04
Category : Science
ISBN : 9789811659935

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Machine Learning and Systems Biology in Genomics and Health by Shailza Singh Pdf

This book discusses the application of machine learning in genomics. Machine Learning offers ample opportunities for Big Data to be assimilated and comprehended effectively using different frameworks. Stratification, diagnosis, classification and survival predictions encompass the different health care regimes representing unique challenges for data pre-processing, model training, refinement of the systems with clinical implications. The book discusses different models for in-depth analysis of different conditions. Machine Learning techniques have revolutionized genomic analysis. Different chapters of the book describe the role of Artificial Intelligence in clinical and genomic diagnostics. It discusses how systems biology is exploited in identifying the genetic markers for drug discovery and disease identification. Myriad number of diseases whether be infectious, metabolic, cancer can be dealt in effectively which combines the different omics data for precision medicine. Major breakthroughs in the field would help reflect more new innovations which are at their pinnacle stage. This book is useful for researchers in the fields of genomics, genetics, computational biology and bioinformatics.

Integrative Genomics and Network Biology in Livestock and other Domestic Animals

Author : David E. MacHugh,Robert J. Schaefer
Publisher : Frontiers Media SA
Page : 450 pages
File Size : 51,7 Mb
Release : 2020-09-11
Category : Medical
ISBN : 9782889639991

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Integrative Genomics and Network Biology in Livestock and other Domestic Animals by David E. MacHugh,Robert J. Schaefer Pdf

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Artificial Intelligence

Author : Anonim
Publisher : BoD – Books on Demand
Page : 142 pages
File Size : 55,5 Mb
Release : 2019-07-31
Category : Medical
ISBN : 9781789840179

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Artificial Intelligence by Anonim Pdf

Artificial intelligence (AI) is taking on an increasingly important role in our society today. In the early days, machines fulfilled only manual activities. Nowadays, these machines extend their capabilities to cognitive tasks as well. And now AI is poised to make a huge contribution to medical and biological applications. From medical equipment to diagnosing and predicting disease to image and video processing, among others, AI has proven to be an area with great potential. The ability of AI to make informed decisions, learn and perceive the environment, and predict certain behavior, among its many other skills, makes this application of paramount importance in today's world. This book discusses and examines AI applications in medicine and biology as well as challenges and opportunities in this fascinating area.

Data Driven Science for Clinically Actionable Knowledge in Diseases

Author : Daniel Catchpoole,Simeon Simoff,Paul Kennedy,Quang Vinh Nguyen
Publisher : CRC Press
Page : 255 pages
File Size : 50,9 Mb
Release : 2023-12-06
Category : Medical
ISBN : 9781003800286

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Data Driven Science for Clinically Actionable Knowledge in Diseases by Daniel Catchpoole,Simeon Simoff,Paul Kennedy,Quang Vinh Nguyen Pdf

Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.

Machine Learning in Dentistry

Author : Ching-Chang Ko,Dinggang Shen,Li Wang
Publisher : Springer Nature
Page : 186 pages
File Size : 54,7 Mb
Release : 2021-07-24
Category : Medical
ISBN : 9783030718817

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Machine Learning in Dentistry by Ching-Chang Ko,Dinggang Shen,Li Wang Pdf

This book reviews all aspects of the use of machine learning in contemporary dentistry, clearly explaining its significance for dental imaging, oral diagnosis and treatment, dental designs, and dental research. Machine learning is an emerging field of artificial intelligence research and practice in which computer agents are employed to improve perception, cognition, and action based on their ability to “learn”, for example through use of big data techniques. Its application within dentistry is designed to promote personalized and precision patient care, with enhancement of diagnosis and treatment planning. In this book, readers will find up-to-date information on different machine learning tools and their applicability in various dental specialties. The selected examples amply illustrate the opportunities to employ a machine learning approach within dentistry while also serving to highlight the associated challenges. Machine Learning in Dentistry will be of value for all dental practitioners and researchers who wish to learn more about the potential benefits of using machine learning techniques in their work.

Big Data in Omics and Imaging

Author : Momiao Xiong
Publisher : CRC Press
Page : 400 pages
File Size : 46,5 Mb
Release : 2018-06-14
Category : Mathematics
ISBN : 9781351172622

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Big Data in Omics and Imaging by Momiao Xiong Pdf

Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning and causal revolution to developing a new generation of genetic analysis for shifting the current paradigm of genetic analysis from shallow association analysis to deep causal inference and from genetic analysis alone to integrated omics and imaging data analysis for unraveling the mechanism of complex diseases. FEATURES Provides a natural extension and companion volume to Big Data in Omic and Imaging: Association Analysis, but can be read independently. Introduce causal inference theory to genomic, epigenomic and imaging data analysis Develop novel statistics for genome-wide causation studies and epigenome-wide causation studies. Bridge the gap between the traditional association analysis and modern causation analysis Use combinatorial optimization methods and various causal models as a general framework for inferring multilevel omic and image causal networks Present statistical methods and computational algorithms for searching causal paths from genetic variant to disease Develop causal machine learning methods integrating causal inference and machine learning Develop statistics for testing significant difference in directed edge, path, and graphs, and for assessing causal relationships between two networks The book is designed for graduate students and researchers in genomics, epigenomics, medical image, bioinformatics, and data science. Topics covered are: mathematical formulation of causal inference, information geometry for causal inference, topology group and Haar measure, additive noise models, distance correlation, multivariate causal inference and causal networks, dynamic causal networks, multivariate and functional structural equation models, mixed structural equation models, causal inference with confounders, integer programming, deep learning and differential equations for wearable computing, genetic analysis of function-valued traits, RNA-seq data analysis, causal networks for genetic methylation analysis, gene expression and methylation deconvolution, cell –specific causal networks, deep learning for image segmentation and image analysis, imaging and genomic data analysis, integrated multilevel causal genomic, epigenomic and imaging data analysis.

Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 1211 pages
File Size : 49,7 Mb
Release : 2013-05-01
Category : Computers
ISBN : 9781490105970

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Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition by Anonim Pdf

Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Expert Systems. The editors have built Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Expert Systems in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Artificial Intelligence, Robotics and Machine Learning: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Knowledge and Systems Engineering

Author : Viet-Ha Nguyen,Anh-Cuong Le,Van-Nam Huynh
Publisher : Springer
Page : 673 pages
File Size : 43,7 Mb
Release : 2014-09-29
Category : Technology & Engineering
ISBN : 9783319116808

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Knowledge and Systems Engineering by Viet-Ha Nguyen,Anh-Cuong Le,Van-Nam Huynh Pdf

This volume contains papers presented at the Sixth International Conference on Knowledge and Systems Engineering (KSE 2014), which was held in Hanoi, Vietnam, during 9–11 October, 2014. The conference was organized by the University of Engineering and Technology, Vietnam National University, Hanoi. Besides the main track of contributed papers, this proceedings feature the results of four special sessions focusing on specific topics of interest and three invited keynote speeches. The book gathers a total of 51 carefully reviewed papers describing recent advances and development on various topics including knowledge discovery and data mining, natural language processing, expert systems, intelligent decision making, computational biology, computational modeling, optimization algorithms, and industrial applications.

Deep Learning for Biomedical Applications

Author : Utku Kose,Omer Deperlioglu,D. Jude Hemanth
Publisher : CRC Press
Page : 364 pages
File Size : 40,8 Mb
Release : 2021-07-20
Category : Technology & Engineering
ISBN : 9781000406429

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Deep Learning for Biomedical Applications by Utku Kose,Omer Deperlioglu,D. Jude Hemanth Pdf

This book is a detailed reference on biomedical applications using Deep Learning. Because Deep Learning is an important actor shaping the future of Artificial Intelligence, its specific and innovative solutions for both medical and biomedical are very critical. This book provides a recent view of research works on essential, and advanced topics. The book offers detailed information on the application of Deep Learning for solving biomedical problems. It focuses on different types of data (i.e. raw data, signal-time series, medical images) to enable readers to understand the effectiveness and the potential. It includes topics such as disease diagnosis, image processing perspectives, and even genomics. It takes the reader through different sides of Deep Learning oriented solutions. The specific and innovative solutions covered in this book for both medical and biomedical applications are critical to scientists, researchers, practitioners, professionals, and educations who are working in the context of the topics.

Data Mining and Medical Knowledge Management: Cases and Applications

Author : Berka, Petr,Rauch, Jan,Zighed, Djamel Abdelkader
Publisher : IGI Global
Page : 464 pages
File Size : 46,7 Mb
Release : 2009-02-28
Category : Computers
ISBN : 9781605662190

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Data Mining and Medical Knowledge Management: Cases and Applications by Berka, Petr,Rauch, Jan,Zighed, Djamel Abdelkader Pdf

The healthcare industry produces a constant flow of data, creating a need for deep analysis of databases through data mining tools and techniques resulting in expanded medical research, diagnosis, and treatment. Data Mining and Medical Knowledge Management: Cases and Applications presents case studies on applications of various modern data mining methods in several important areas of medicine, covering classical data mining methods, elaborated approaches related to mining in electroencephalogram and electrocardiogram data, and methods related to mining in genetic data. A premier resource for those involved in data mining and medical knowledge management, this book tackles ethical issues related to cost-sensitive learning in medicine and produces theoretical contributions concerning general problems of data, information, knowledge, and ontologies.

Encyclopedia of Cell Biology

Author : Anonim
Publisher : Academic Press
Page : 2972 pages
File Size : 40,6 Mb
Release : 2015-08-07
Category : Science
ISBN : 9780123947963

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Encyclopedia of Cell Biology by Anonim Pdf

The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences