Magnesium In Human Health And Disease

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Magnesium in Human Health and Disease

Author : Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 46,8 Mb
Release : 2012-09-14
Category : Medical
ISBN : 9781627030434

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Magnesium in Human Health and Disease by Ronald Ross Watson,Victor R. Preedy,Sherma Zibadi Pdf

Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium is a mineral and not synthesizable it must be obtained through dietary foods and/or supplements. Magnesium in Human Health and Disease reviews the benefits of magnesium supplementation to reach recommended intakes as well as provides new research that suggests how reaching levels above the recommended intakes can promote health and treat various diseases. Magnesium deficiency can cause low serum potassium and calcium levels, retention of sodium, and low circulating levels of regulatory hormones. These changes in nutrients cause neurological and muscular symptoms such as tremor and muscle spasms. Further magnesium deficiency causes loss of appetite, nausea, vomiting, personality changes and death from heart failure. Causes of magnesium deficiency include alcohol abuse, poorly controlled diabetes, excessive or chronic vomiting and/or diarrhea. Thus the effects of inadequate and deficient intakes or levels of magnesium is critical to health and are reviewed by the expert clinicians in this book. Magnesium in Human Health and Disease provides the most current research to support the potential benefits or lack thereof for normal and high supplementation with magnesium. Animal model research and early human trials are reviewed to document other disease states such as hypertension, cholesterol level, type 2 diabetes and cardiovascular disease that would benefit from increased magnesium.

Magnesium in the Central Nervous System

Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 43,8 Mb
Release : 2011
Category : Medical
ISBN : 9780987073051

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Magnesium in the Central Nervous System by Robert Vink,Mihai Nechifor Pdf

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Magnesium Intake and Human Health

Author : Federica Wolf,Valentina Trapani
Publisher : MDPI
Page : 183 pages
File Size : 53,5 Mb
Release : 2018-11-16
Category : Electronic books
ISBN : 9783038973348

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Magnesium Intake and Human Health by Federica Wolf,Valentina Trapani Pdf

This book is a printed edition of the Special Issue "Magnesium Intake and Human Health" that was published in Nutrients

Calcium and Magnesium in Drinking-water

Author : World Health Organization
Publisher : World Health Organization
Page : 194 pages
File Size : 55,5 Mb
Release : 2009
Category : Business & Economics
ISBN : 9789241563550

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Calcium and Magnesium in Drinking-water by World Health Organization Pdf

Can calcium and magnesium ("hardness") in drinking water contribute to preventing disease? This book documents the outputs of an unprecedented group of experts assembled by the World Health Organization to address this question. It includes their comprehensive consensus view on what is known and what is not about the role and possible health benefit of calcium and magnesium in drinking-water. Also included is a series of chapters each authored by internationally renowned experts reviewing the state of the art in different aspects including: global dietary calcium and magnesium intakes; the contribution of drinking water to calcium and magnesium intake; health significance of calcium and magnesium; role of drinking-water in relation to bone metabolism; epidemiological studies and the association of cardiovascular disease risks with water hardness and magnesium in particular; water production; technical issues and economics. In both developed and developing countries, typical diets are often deficient in calcium and magnesium--essential minerals which are necessary for the development of strong bones and teeth, and for cardiovascular function. At the same time, there is evidence that consuming "hard" drinking-water may be associated with reduced risks for some diseases. Climate change and other ongoing changes will increase the use of high tech treatments--for example desalination and reclamation of polluted waters and mean that the issue will be of increasing future importance.

Interrelations between Essential Metal Ions and Human Diseases

Author : Astrid Sigel,Helmut Sigel,Roland K.O. Sigel
Publisher : Springer Science & Business Media
Page : 603 pages
File Size : 49,6 Mb
Release : 2014-01-27
Category : Science
ISBN : 9789400775008

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Interrelations between Essential Metal Ions and Human Diseases by Astrid Sigel,Helmut Sigel,Roland K.O. Sigel Pdf

MILS-13 provides an up-to-date review on the relationships between essential metals and human diseases, covering 13 metals and 3 metalloids: The bulk metals sodium, potassium, magnesium, and calcium, plus the trace elements manganese, iron, cobalt, copper, zinc, molybdenum, and selenium, all of which are essential for life. Also covered are chromium, vanadium, nickel, silicon, and arsenic, which have been proposed as being essential for humans in the 2nd half of the last century. However, if at all, they are needed only in ultra-trace amounts, and because of their prevalence in the environment, it has been difficult to prove whether or not they are required. In any case, all these elements are toxic in higher concentrations and therefore, transport and cellular concentrations of at least the essential ones, are tightly controlled; hence, their homeostasis and role for life, including deficiency or overload, and their links to illnesses, including cancer and neurological disorders, are thoroughly discussed. Indeed, it is an old wisdom that metals are indispensable for life. Therefore, Volume 13 provides in an authoritative and timely manner in 16 stimulating chapters, written by 29 internationally recognized experts from 7 nations, and supported by more than 2750 references, and over 20 tables and 80 illustrations, many in color, a most up-to-date view on the vibrant research area of the Interrelations between Essential Metal Ions and Human Diseases.

Diet and Health

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Diet and Health
Publisher : National Academies Press
Page : 765 pages
File Size : 55,8 Mb
Release : 1989-01-01
Category : Medical
ISBN : 9780309039949

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Diet and Health by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Diet and Health Pdf

Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Transdermal Magnesium Therapy

Author : Dr. Mark Sircus
Publisher : iUniverse
Page : 360 pages
File Size : 43,7 Mb
Release : 2011-07-07
Category : Medical
ISBN : 9781450283564

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Transdermal Magnesium Therapy by Dr. Mark Sircus Pdf

This second edition of Transdermal Magnesium Therapy offers a full medical review of how magnesium affects cancer, the heart, diabetes, the emotions, inflammation, surgery, autism, transdermal medicine, and so much more. Magnesium is nothing short of a miracle; it has the potential to save you from considerable suffering and pain. The information presented here could even save your life. Magnesium is the lamp of life and one of the most important keys to overall health. When applied in the correct way, magnesium offers us a return to strength and vigor. When used in the emergency room, magnesium can save the day for both heart and stroke patients. What you will be introduced to is magnesium oil, a natural concentrated form of magnesium chloride that can be applied directly to the skin for intense effect. When we are deficient in magnesium, over three hundred enzymes in our body are unable to function properly. Magnesium deficiency has been scientifically identified as a critical factor in the onset of a wide variety of diseases. For various reasons and to varying degree, two-thirds or more of the population is magnesium deficient. Learn how to use this powerful secret to good health in Transdermal Magnesium Therapy.

Modern Nutrition in Health and Disease

Author : A. Catherine Ross,Benjamin Caballero,Robert J. Cousins,Katherine L. Tucker
Publisher : Jones & Bartlett Learning
Page : 1645 pages
File Size : 44,6 Mb
Release : 2020-07-10
Category : Health & Fitness
ISBN : 9781284229851

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Modern Nutrition in Health and Disease by A. Catherine Ross,Benjamin Caballero,Robert J. Cousins,Katherine L. Tucker Pdf

This widely acclaimed book is a complete, authoritative reference on nutrition and its role in contemporary medicine, dietetics, nursing, public health, and public policy. Distinguished international experts provide in-depth information on historical landmarks in nutrition, specific dietary components, nutrition in integrated biologic systems, nutritional assessment through the life cycle, nutrition in various clinical disorders, and public health and policy issues. Modern Nutrition in Health and Disease, Eleventh Edition, offers coverage of nutrition's role in disease prevention, international nutrition issues, public health concerns, the role of obesity in a variety of chronic illnesses, genetics as it applies to nutrition, and areas of major scientific progress relating nutrition to disease.

Vitamin and Mineral Requirements in Human Nutrition

Author : World Health Organization,FAO
Publisher : World Health Organization
Page : 362 pages
File Size : 42,5 Mb
Release : 2004
Category : Medical
ISBN : 9789241546126

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Vitamin and Mineral Requirements in Human Nutrition by World Health Organization,FAO Pdf

In the past 20 years micronutrients have assumed great public health importance and a considerable amount of research has lead to increasing knowledge of their physiological role. Because it is a rapidly developing field, the WHO and FAO convened an Expert Consultation to evaluate the current state of knowledge. It had three main tasks: to review the full scope of vitamin and minerals requirements; to draft and adopt a report which would provide recommended nutrient intakes for vitamins A, C, D, E, and K; the B vitamins; calcium; iron; magnesium; zinc; selenium; and iodine; to identify key issues for future research and make preliminary recommendations for the handbook. This report contains the outcome of the Consultation, combined with up-to-date evidence that has since become available.

Microbiome in Human Health and Disease

Author : Pallaval Veera Bramhachari
Publisher : Springer Nature
Page : 306 pages
File Size : 41,6 Mb
Release : 2021-10-18
Category : Medical
ISBN : 9789811631566

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Microbiome in Human Health and Disease by Pallaval Veera Bramhachari Pdf

The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.

Magnesium and Man

Author : Warren E. C. Wacker
Publisher : Unknown
Page : 192 pages
File Size : 55,7 Mb
Release : 1980
Category : Magnesium in the body
ISBN : UOM:39015063091816

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Magnesium and Man by Warren E. C. Wacker Pdf

Magnesium and Man provides the physician with a brief yet comprehensive overview of magnesium as a biochemical agent in human metabolism and disease. The first half of the book introduces techniques of measurement as well as the role of magnesium in normal biochemistry and physiology. The remaining chapters discuss magnesium squarely in the context of human disease: neonatal deficiency, thyroid disease, kidney disease, malignant osteolytic disease, alcoholism, and cirrhosis. Written by a clinician who is also a dominant figure in magnesium research, this book greatly advances communication between laboratory and clinic and will be essential reading for anyone involved in patient care.

Drinking Water Quality and Human Health

Author : Patrick Levallois,Cristina Villanueva Belmonte
Publisher : MDPI
Page : 374 pages
File Size : 49,9 Mb
Release : 2019-04-04
Category : Medical
ISBN : 9783038977261

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Drinking Water Quality and Human Health by Patrick Levallois,Cristina Villanueva Belmonte Pdf

The quality of drinking water is paramount for public health. Despite important improvements in the last decades, access to safe drinking water is not universal. The World Health Organization estimates that almost 10% of the population in the world do not have access to improved drinking water sources. Among other diseases, waterborne infections cause diarrhea, which kills nearly one million people every year, mostly children under 5 years of age. On the other hand, chemical pollution is a concern in high-income countries and an increasing problem in low- and middle-income countries. Exposure to chemicals in drinking water may lead to a range of chronic non-communicable diseases (e.g., cancer, cardiovascular disease), adverse reproductive outcomes, and effects on children’s health (e.g., neurodevelopment), among other health effects. Although drinking water quality is regulated and monitored in many countries, increasing knowledge leads to the need for reviewing standards and guidelines on a nearly permanent basis, both for regulated and newly identified contaminants. Drinking water standards are mostly based on animal toxicity data, and more robust epidemiologic studies with accurate exposure assessment are needed. The current risk assessment paradigm dealing mostly with one-by-one chemicals dismisses the potential synergisms or interactions from exposures to mixtures of contaminants, particularly at the low-exposure range. Thus, evidence is needed on exposure and health effects of mixtures of contaminants in drinking water. Finally, water stress and water quality problems are expected to increase in the coming years due to climate change and increasing water demand by population growth, and new evidence is needed to design appropriate adaptation policies. This Special Issue of International Journal of Environmental Research and Public Health (IJERPH) focuses on the current state of knowledge on the links between drinking water quality and human health.

Magnesium Deficiency in the Pathogenesis of Disease

Author : Mildred S. Seelig
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 45,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781468491081

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Magnesium Deficiency in the Pathogenesis of Disease by Mildred S. Seelig Pdf

There is a large and rapidly growing body of literature on the importance of mag nesium in biochemical and physiological processes. There is also much evidence that magnesium deficiency, alone and in combination with agents that interfere with its utilization, is associated with functional and structural abnormalities of mem branes, cells, organs, and systems. The manifestations of the changes caused by magnesium deficiency depend upon its extent and duration and on variable factors. Among the conditions that increase the risk of magnesium deficiency are (1) meta bolic factors that affect the absorption, distribution, and excretion of this mineral; (2) disease and therapy; (3) physiologic states that increase requirements for nutrients; and (4) nutritional imbalances. Excesses of nutrients that interfere with the absorption or increase the excretion of magnesium-such as fat, phosphate, sugar, and vitamin D-can contribute to long-lasting relative magnesium deficiency. All have been implicated in several of the diseases considered in this book. Whether their influence on the need for magnesium is a common denominator remains to be investigated further.

Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride

Author : Institute of Medicine,Food and Nutrition Board,Standing Committee on the Scientific Evaluation of Dietary Reference Intakes
Publisher : National Academies Press
Page : 449 pages
File Size : 43,9 Mb
Release : 1999-10-17
Category : Medical
ISBN : 9780309064033

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Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride by Institute of Medicine,Food and Nutrition Board,Standing Committee on the Scientific Evaluation of Dietary Reference Intakes Pdf

Since 1941, Recommended Dietary Allowances (RDAs) has been recognized as the most authoritative source of information on nutrient levels for healthy people. Since publication of the 10th edition in 1989, there has been rising awareness of the impact of nutrition on chronic disease. In light of new research findings and a growing public focus on nutrition and health, the expert panel responsible for formulation RDAs reviewed and expanded its approachâ€"the result: Dietary Reference Intakes. This new series of references greatly extends the scope and application of previous nutrient guidelines. For each nutrient the book presents what is known about how the nutrient functions in the human body, what the best method is to determine its requirements, which factors (caffeine or exercise, for example) may affect how it works, and how the nutrient may be related to chronic disease. The first volume of Dietary Reference Intakes includes calcium, phosphorus, magnesium, vitamin D, and fluoride. The second book in the series presents information about thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. Based on analysis of nutrient metabolism in humans and data on intakes in the U.S. population, the committee recommends intakes for each age groupâ€"from the first days of life through childhood, sexual maturity, midlife, and the later years. Recommendations for pregnancy and lactation also are made, and the book identifies when intake of a nutrient may be too much. Representing a new paradigm for the nutrition community, Dietary Reference Intakes encompasses: Estimated Average Requirements (EARs). These are used to set Recommended Dietary Allowances. Recommended Dietary Allowances (RDAs). Intakes that meet the RDA are likely to meet the nutrient requirement of nearly all individuals in a life-stage and gender group. Adequate Intakes (AIs). These are used instead of RDAs when an EAR cannot be calculated. Both the RDA and the AI may be used as goals for individual intake. Tolerable Upper Intake Levels (ULs). Intakes below the UL are unlikely to pose risks of adverse health effects in healthy people. This new framework encompasses both essential nutrients and other food components thought to pay a role in health, such as dietary fiber. It incorporates functional endpoints and examines the relationship between dose and response in determining adequacy and the hazards of excess intake for each nutrient.

The Spectrum of Mineral and Bone Disorders in Chronic Kidney Disease

Author : Klaus Olgaard,Isidro B. Salusky,Justin Silver
Publisher : Oxford University Press
Page : 617 pages
File Size : 52,7 Mb
Release : 2010-06-10
Category : Medical
ISBN : 9780199559176

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The Spectrum of Mineral and Bone Disorders in Chronic Kidney Disease by Klaus Olgaard,Isidro B. Salusky,Justin Silver Pdf

Rev. ed. of: Spectrum of renal osteodystrophy / edited by Tilman Drueke, Isidro B. Salusky. 1st. 2001.