Magnetic Resonance Spectroscopy

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Magnetic Resonance Spectroscopy

Charlotte Stagg,Douglas L. Rothman
Magnetic Resonance Spectroscopy Book PDF

Author : Charlotte Stagg,Douglas L. Rothman
Publisher : Academic Press
Page : 398 pages
File Size : 45,6 Mb
Release : 2013-11-11
Category : Medical
ISBN : 9780124016972

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Magnetic Resonance Spectroscopy by Charlotte Stagg,Douglas L. Rothman Pdf

Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. Chapters written by world-leading experts in the field Fully illustrated Covers both proton and non-proton MRS Includes the background to novel MRS imaging approaches

Magnetic Resonance Spectroscopy

Charlotte Stagg,Douglas Rothman
Magnetic Resonance Spectroscopy Book PDF

Author : Charlotte Stagg,Douglas Rothman
Publisher : Academic Press
Page : 0 pages
File Size : 54,9 Mb
Release : 2013-12-10
Category : Medical
ISBN : 012401688X

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Magnetic Resonance Spectroscopy by Charlotte Stagg,Douglas Rothman Pdf

Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective.

Magnetic Resonance Spectroscopy

Dong-Hyun Kim
Magnetic Resonance Spectroscopy Book PDF

Author : Dong-Hyun Kim
Publisher : BoD – Books on Demand
Page : 278 pages
File Size : 49,7 Mb
Release : 2012-03-02
Category : Medical
ISBN : 9789535100652

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Magnetic Resonance Spectroscopy by Dong-Hyun Kim Pdf

Magnetic Resonance Spectroscopy (MRS) is a unique tool to probe the biochemistry in vivo providing metabolic information non-invasively. Applications using MRS has been found over a broad spectrum in investigating the underlying structures of compounds as well as in determining disease states. In this book, topics of MRS both relevant to the clinic and also those that are beyond the clinical arena are covered. The book consists of two sections. The first section is entitled 'MRS inside the clinic' and is focused on clinical applications of MRS while the second section is entitled 'MRS beyond the clinic' and discusses applications of MRS in other academic fields. Our hope is that through this book, readers can understand the broad applications that NMR and MRS can offer and also that there are enough references to guide the readers for further study in this important topic.

Nuclear Magnetic Resonance Spectroscopy

Joseph B. Lambert,Eugene P. Mazzola,Clark D. Ridge
Nuclear Magnetic Resonance Spectroscopy Book PDF

Author : Joseph B. Lambert,Eugene P. Mazzola,Clark D. Ridge
Publisher : John Wiley & Sons
Page : 485 pages
File Size : 45,9 Mb
Release : 2019-01-04
Category : Science
ISBN : 9781119295235

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Nuclear Magnetic Resonance Spectroscopy by Joseph B. Lambert,Eugene P. Mazzola,Clark D. Ridge Pdf

Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.

Handbook of Magnetic Resonance Spectroscopy In Vivo

Paul A. Bottomley,John R. Griffiths
Handbook of Magnetic Resonance Spectroscopy In Vivo Book PDF

Author : Paul A. Bottomley,John R. Griffiths
Publisher : John Wiley & Sons
Page : 1232 pages
File Size : 54,5 Mb
Release : 2016-10-19
Category : Medical
ISBN : 9781118997697

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Handbook of Magnetic Resonance Spectroscopy In Vivo by Paul A. Bottomley,John R. Griffiths Pdf

This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage

MR Spectroscopy of Pediatric Brain Disorders

Stefan Blüml,Ashok Panigrahy
MR Spectroscopy of Pediatric Brain Disorders Book PDF

Author : Stefan Blüml,Ashok Panigrahy
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 52,6 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9781441958648

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MR Spectroscopy of Pediatric Brain Disorders by Stefan Blüml,Ashok Panigrahy Pdf

Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.

Clinical MR Spectroscopy

Peter B. Barker,Alberto Bizzi,Nicola De Stefano,Doris D. M. Lin,Rao Gullapalli
Clinical MR Spectroscopy Book PDF

Author : Peter B. Barker,Alberto Bizzi,Nicola De Stefano,Doris D. M. Lin,Rao Gullapalli
Publisher : Cambridge University Press
Page : 275 pages
File Size : 51,8 Mb
Release : 2010
Category : Medical
ISBN : 9780521868983

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Clinical MR Spectroscopy by Peter B. Barker,Alberto Bizzi,Nicola De Stefano,Doris D. M. Lin,Rao Gullapalli Pdf

Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases

Else Rubaek Danielsen,Brian Ross
Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases Book PDF

Author : Else Rubaek Danielsen,Brian Ross
Publisher : CRC Press
Page : 344 pages
File Size : 44,9 Mb
Release : 1999-02-16
Category : Medical
ISBN : 9781482270105

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Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases by Else Rubaek Danielsen,Brian Ross Pdf

Demonstrates how MRS offers a useful tool for the noninvasive biochemical analysis of the brain. The book covers over 70 clinical cases and more than 100 spectra that enhance skills at interpreting MRS, including minimizing errors, highlighting artifacts, and expanding the clinical usefulness of this diagnostic modality.

In Vivo NMR Spectroscopy

Robin A. de Graaf
In Vivo NMR Spectroscopy Book PDF

Author : Robin A. de Graaf
Publisher : John Wiley & Sons
Page : 584 pages
File Size : 50,7 Mb
Release : 2019-03-11
Category : Science
ISBN : 9781119382546

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In Vivo NMR Spectroscopy by Robin A. de Graaf Pdf

Presents basic concepts, experimental methodology and data acquisition, and processing standards of in vivo NMR spectroscopy This book covers, in detail, the technical and biophysical aspects of in vivo NMR techniques and includes novel developments in the field such as hyperpolarized NMR, dynamic 13C NMR, automated shimming, and parallel acquisitions. Most of the techniques are described from an educational point of view, yet it still retains the practical aspects appreciated by experimental NMR spectroscopists. In addition, each chapter concludes with a number of exercises designed to review, and often extend, the presented NMR principles and techniques. The third edition of In Vivo NMR Spectroscopy: Principles and Techniques has been updated to include experimental detail on the developing area of hyperpolarization; a description of the semi-LASER sequence, which is now a method of choice; updated chemical shift data, including the addition of 31P data; a troubleshooting section on common problems related to shimming, water suppression, and quantification; recent developments in data acquisition and processing standards; and MatLab scripts on the accompanying website for helping readers calculate radiofrequency pulses. Provide an educational explanation and overview of in vivo NMR, while maintaining the practical aspects appreciated by experimental NMR spectroscopists Features more experimental methodology than the previous edition End-of-chapter exercises that help drive home the principles and techniques and offer a more in-depth exploration of quantitative MR equations Designed to be used in conjunction with a teaching course on the subject In Vivo NMR Spectroscopy: Principles and Techniques, 3rd Edition is aimed at all those involved in fundamental and/or diagnostic in vivo NMR, ranging from people working in dedicated in vivo NMR institutes, to radiologists in hospitals, researchers in high-resolution NMR and MRI, and in areas such as neurology, physiology, chemistry, and medical biology.

Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry

Lloyd Miles Jackman,S. Sternhell
Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry Book PDF

Author : Lloyd Miles Jackman,S. Sternhell
Publisher : Pergamon
Page : 456 pages
File Size : 41,5 Mb
Release : 1978
Category : Chemistry, Organic
ISBN : 0080229530

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Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry by Lloyd Miles Jackman,S. Sternhell Pdf

Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry, Second Edition focuses on the applications of nuclear magnetic resonance spectroscopy to problems in organic chemistry and the theories involved in this kind of spectroscopy. The book first discusses the theory of nuclear magnetic resonance, including dynamic and magnetic properties of atomic nuclei, nuclear resonance, and relaxation process. The manuscript also examines the experimental method. Topics include experimental factors that influence resolution and the shapes of absorption lines; measurement of line posit...

Nuclear Magnetic Resonance Spectroscopy of Boron Compounds

Heinrich Nöth,Bernd Wrackmeyer
Nuclear Magnetic Resonance Spectroscopy of Boron Compounds Book PDF

Author : Heinrich Nöth,Bernd Wrackmeyer
Publisher : Springer Science & Business Media
Page : 474 pages
File Size : 40,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642667572

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Nuclear Magnetic Resonance Spectroscopy of Boron Compounds by Heinrich Nöth,Bernd Wrackmeyer Pdf

The revolutionary impetus of the NMR methods in organic chemistry has parallels in the field of boron chemistry. lIB NMR spectroscopy provided a basis for the elucida tion of structures and reactions of the boron hydrides. However, although many studies have been carried out with the higher boranes, carboranes, metalloboranes, etc. , and although certain patterns have emerged, the correlation between the observed chemical shift and the assigned structural unit is still not fully understood. Therefore, predictions in this area are still rather limited, and semiquantitative interpretations are not yet pos sible. Several years ago Eaton and Lipscomb sUpImarized the status in this field in their book "NMR Studies of Boron Hydrides and Related Compounds" and a plethora of new data has accumulated since then. The book also contained material on simple bo rane derivatives, but they were not discussed in any detail. On the other hand many systematic studies, both synthetic and spectroscopic, have been conducted on these simple boron materials in the last decade. Thus a large amount of NMR information is available, not only on lIB but also on 1 H, 1 3 C, and 14 N. However, this information is widely scattered in the literature, and often the data are not discussed at all. It see med appropriate, therefore, to collect these data and to present them in one volume.

Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

Jacob Valk,Marjo S. van der Knaap
Magnetic Resonance of Myelin Myelination and Myelin Disorders Book PDF

Author : Jacob Valk,Marjo S. van der Knaap
Publisher : Springer Science & Business Media
Page : 390 pages
File Size : 51,8 Mb
Release : 2013-04-17
Category : Medical
ISBN : 9783662025680

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Magnetic Resonance of Myelin, Myelination, and Myelin Disorders by Jacob Valk,Marjo S. van der Knaap Pdf

Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.

Foundations of Sport-Related Brain Injuries

Semyon M. Slobounov,Wayne J. Sebastianelli
Foundations of Sport Related Brain Injuries Book PDF

Author : Semyon M. Slobounov,Wayne J. Sebastianelli
Publisher : Springer Science & Business Media
Page : 482 pages
File Size : 41,5 Mb
Release : 2006-08-25
Category : Medical
ISBN : 9780387325651

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Foundations of Sport-Related Brain Injuries by Semyon M. Slobounov,Wayne J. Sebastianelli Pdf

In summarizing current insights and controversies over concussions in athletics, this book makes the vital point that symptom resolution does not necessarily mean injury resolution. Research shows that dysfunctional pathways continue for extended periods even after a minor concussion. Until the consequences of short-term perturbations and long-term residual brain dysfunctions are better understood, concussions must be treated with respect and given a higher priority for continued research activity.

Magnetic Resonance Spectroscopy in Multiple Sclerosis

M. Filippi,D.L. Arnold,G. Comi
Magnetic Resonance Spectroscopy in Multiple Sclerosis Book PDF

Author : M. Filippi,D.L. Arnold,G. Comi
Publisher : Springer Science & Business Media
Page : 153 pages
File Size : 54,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9788847021099

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Magnetic Resonance Spectroscopy in Multiple Sclerosis by M. Filippi,D.L. Arnold,G. Comi Pdf

Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of pathological specificity for the heterogeneous substrates of multiple sclerosis (MS). Magnetic resonance spectroscopy (MRS) is one of the most promising of these techniques. Thanks to MRS, axonal damage is no longer considered an end-stage phenomenon typical of only the most destructive lesions and the most unfortunate cases, but rather as a major component of the MS pathology of lesions and normal-appearing white matter at all the phases of the disease. This new concept is rapidly changing our understanding of MS pathophysiology and, as a consequence, the therapeutic strategies to modify the disease course favorably. Many of the authors have pionereed the use of MRS in MS, thus contributing to the foundation of the "axonal hypothesis".

Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy

Peder Larson
Hyperpolarized Carbon 13 Magnetic Resonance Imaging and Spectroscopy Book PDF

Author : Peder Larson
Publisher : Academic Press
Page : 298 pages
File Size : 43,7 Mb
Release : 2021-11-28
Category : Psychology
ISBN : 9780128222706

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Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy by Peder Larson Pdf

MRI with hyperpolarized carbon-13 agents is a powerful emerging imaging modality that can measure real-time metabolism in cells, animals, and humans. It uses endogenous, non-toxic contrast agents that a hyperpolarized, resulting in up to 100,000-fold increases in sensitivity. This technique uses no ionizing radiation, and is being applied in a range of human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis. Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is designed to be a one stop shop for understanding hyperpolarized 13C MRI. This book explains the principles of this imaging modality, the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. It is suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology. Presents the physics and hardware of dissolution dynamic nuclear polarization Explains the behaviour of hyperpolarized carbon-13 agents and how to image them Detailed guidance on experimental design and data interpretation Identifies promising and potential applications of hyperpolarized carbon-13 MR