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Author : Charles L. Greenblatt,Dan T. Spira
Publisher : Unknown
Page : 215 pages
File Size : 48,8 Mb
Release : 1978
Category : Electronic
ISBN : OCLC:163304892
Author : Jean Langhorne
Publisher : Springer Science & Business Media
Page : 239 pages
File Size : 48,8 Mb
Release : 2006-01-09
Category : Medical
ISBN : 9783540299677
Malaria is still a major global health problem, killing more than 1 million people every year. Almost all of these deaths are caused by Plasmodium falciparum, one of the four species of malaria parasites infecting humans. This high burden of mortality falls heavily on Sub-Saharan Africa, where over 90% of these deaths are thought to occur, and 5% of children die before the age of 5 years. The death toll from malaria is still growing, with malaria-specific mortality in young African children estimated to have doubled during the last twenty years. This increase has been associated with drug resistance of the parasite, spread of insecticide resistant mosquitoes, poverty, social and political upheaval, and lack of effective vaccines. This collection of reviews addresses many of these important issues of malarial immunity and immunopathology. They are of interest not only to malariologists, but hopefully also to the broader immunological community. Strong interactions with, and feedback from immunologists working in other infectious diseases and in basic immunology will help us to move the field of malaria immunology and therapeutic intervention forward more quickly.
Author : Peter Perlmann,Marita Troye-Blomberg
Publisher : Karger Medical and Scientific Publishers
Page : 422 pages
File Size : 52,6 Mb
Release : 2002-01-01
Category : Medical
ISBN : 9783805573764
Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.
Author : Dan T. Spira,Charles L. Greenblatt
Publisher : S Karger Ag
Page : 215 pages
File Size : 48,8 Mb
Release : 1978
Category : Medical
ISBN : 3805529406
Author : Anonim
Publisher : Unknown
Page : 372 pages
File Size : 55,5 Mb
Release : 1988
Category : Electronic
ISBN : OCLC:636652851
Author : Julius P. Kreier
Publisher : Academic Press
Page : 365 pages
File Size : 51,9 Mb
Release : 2014-05-12
Category : Medical
ISBN : 9781483257471
Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.
Author : Theodore P. Zacharia
Publisher : New York : M. Dekker
Page : 296 pages
File Size : 53,7 Mb
Release : 1973
Category : Immunology
ISBN : UCAL:B4357113
Author : Maria M. Mota,Ana Rodriguez
Publisher : Springer
Page : 278 pages
File Size : 40,9 Mb
Release : 2018-04-30
Category : Medical
ISBN : 3319832395
Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use. However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following: - Contributions by top research leaders in the field, - Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.
Author : Steven A. Frank
Publisher : Princeton University Press
Page : 364 pages
File Size : 41,7 Mb
Release : 2002-07-21
Category : Medical
ISBN : 0691095957
Publisher Description
Author : Anonim
Publisher : Springer
Page : 0 pages
File Size : 41,6 Mb
Release : 2018-07-12
Category : Medical
ISBN : 1461483255
The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.
Author : Estelle J. Abrams
Publisher : Unknown
Page : 34 pages
File Size : 50,5 Mb
Release : 1981
Category : Malaria
ISBN : MINN:319510028707859
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Institute of Medicine,Board on Health Sciences Policy,Committee on the Use of Chimpanzees in Biomedical and Behavioral Research
Publisher : National Academies Press
Page : 200 pages
File Size : 55,8 Mb
Release : 2012-01-05
Category : Science
ISBN : 9780309220392
For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Author : National Library of Medicine (U.S.)
Publisher : Unknown
Page : 1442 pages
File Size : 46,9 Mb
Release : 1983
Category : Medicine
ISBN : UOM:39015074107650
First multi-year cumulation covers six years: 1965-70.
Author : Maria M. Mota,Ana Rodriguez
Publisher : Springer
Page : 278 pages
File Size : 42,6 Mb
Release : 2017-01-12
Category : Medical
ISBN : 9783319452104
Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use. However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following: - Contributions by top research leaders in the field, - Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.
Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 41,6 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
