Management Of Localized Pancreatic Cancer

Author : Susan Tsai,Paul S. Ritch,Beth A. Erickson,Douglas B. Evans
Publisher : Springer
Page : 205 pages
File Size : 45,7 Mb
Release : 2019-07-30
Category : Medical
ISBN : 9783319989440

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Management of Localized Pancreatic Cancer by Susan Tsai,Paul S. Ritch,Beth A. Erickson,Douglas B. Evans Pdf

This book is designed to present a comprehensive understanding for the rationale of neoadjuvant treatment sequencing for localized pancreatic cancer and to focus on accurate clinical staging and stage-specific treatment sequencing. Sections address important aspects of clinical management of localized pancreatic cancer from diagnosis to surgery. These areas include initial radiographic staging, management of obstructive jaundice, role of chemotherapy and chemoradiation in neoadjuvant therapy, assessment of treatment response, and operative considerations for complex vascular resections. A brief review of suggested readings addressing the particular topic follows in each section, as well as a summary of clinical “pearls”. Management of Localized Pancreatic Cancer: Current Treatment and Challenges provides a comprehensive resource which clearly defines the principles of neoadjuvant therapy as well as a clinical framework for successful therapy. It serves as a valuable guide to physicians of multiple disciplines who are interested in utilizing neoadjuvant therapy for localized pancreatic cancer.

Author : Shubham Pant
Publisher : Springer Nature
Page : 197 pages
File Size : 47,5 Mb
Release : 2023-12-09
Category : Medical
ISBN : 9783031386237

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Pancreatic Cancer by Shubham Pant Pdf

Pancreatic cancer is a challenging and complex disease characterized by a dense fibrotic stroma and an immunosuppressive tumor microenvironment. Until recently, there were no predictive biomarkers to personalize selection of targeted or biologic therapies as a part of standard of care treatment. Moreover, the regulatory immune population of cells creates a “cold”, non-immunogenic tumor that is resistant to immunotherapies including checkpoint inhibitors. However, in the last few years, there has been substantial progress in our understanding of the role mutations in the pathogenesis of disease leading to increased adoption of germline and next generation sequencing to identify mutations and fusions to optimize selection of therapies and select patients for clinical trials of targeted agents. This book provides a comprehensive, global overview on therapy for pancreatic cancer, exploring approved therapies and focusing on the “Next” in drug development including molecularly targeted therapy and efforts at “Drugging the Undruggable”: the KRAS mutation. It also addresses efforts at targeting the inhospitable stroma to improve drug delivery to the tumor cells, incorporating ct DNA (liquid biopsies) in the care of patients and recent advances in immunotherapy. Pancreatic Cancer: Current Therapeutics and Future Directions will illuminate these challenges, review existing therapeutics, and highlight current and future efforts to improve outcomes in this devastating disease. Useful to physicians, fellows, medical students, residents, physician assistants, nurse practitioners, pharmaceutical companies and researchers interested in pancreatic cancer, it will first explain management of localized disease including resectability and adjuvant and neoadjuvant therapies. Targeted therapies including molecular, immunotherapy, stroma and role of ctDNA or “liquid biopsies” will be addressed. Finally, the book will explore the important role of pain management, diet and exercise in improving outcomes in pancreatic cancer.

Author : Susan Tsai,Douglas B. Evans
Publisher : Elsevier Health Sciences
Page : 201 pages
File Size : 52,7 Mb
Release : 2021-09-16
Category : Medical
ISBN : 9780323813600

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Current Management of Pancreatic Cancer, An Issue of Surgical Oncology Clinics of North America, E-Book by Susan Tsai,Douglas B. Evans Pdf

Current Management of Pancreatic Cancer, An Issue of Surgical Oncology Clinics of North America, E-Book

Author : Matthew H.G. Katz,Syed A. Ahmad
Publisher : Springer
Page : 333 pages
File Size : 43,9 Mb
Release : 2015-12-10
Category : Medical
ISBN : 9783319227801

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Multimodality Management of Borderline Resectable Pancreatic Cancer by Matthew H.G. Katz,Syed A. Ahmad Pdf

This volume provides the most comprehensive coverage of clinical management of borderline resectable pancreatic cancer available. Authored by leaders in the field, the book focuses on current clinical management of this disease stage, the importance of multimodality treatment algorithms, and an interdisciplinary approach to care. Surgical chapters are well-illustrated to provide surgeons and surgical trainees with important technical pearls. Clinical trials and trial design are also discussed. Multimodality Management of Borderline Resectable Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, radiation oncologists, surgical oncologists, general surgeons, and trainees interested in the treatment of pancreatic cancer.

Author : Sun-Whe Kim,Hiroki Yamaue
Publisher : Springer
Page : 472 pages
File Size : 55,5 Mb
Release : 2017-05-04
Category : Medical
ISBN : 9783662471814

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Pancreatic Cancer by Sun-Whe Kim,Hiroki Yamaue Pdf

This book provides state of the art knowledge on a broad range of clinical issues in pancreatic cancer, covering topics from screening and pathophysiology to surgical treatments. In particular, the focus is on current controversies and on evidence-based surgical techniques. Further aspects considered include the management of precancerous lesions, diagnostic methods, perioperative care and nonsurgical treatment. The description of surgical methods is supported by many helpful illustrations and important technical issues are carefully addressed. Determination of resectability and extent of surgery is also discussed. Based on recent developments in surgical techniques, some surgeons are performing more and more radical operations. It is essential, however, that surgical strategy is based on the best available evidence and surgeons will find that this book offers valuable help in achieving this aim. In addition, it will be a great asset in clinical practice for all who are involved or interested in the management of pancreatic cancer.

Author : Jeffrey M. Hardacre
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 52,5 Mb
Release : 2016-11-21
Category : Medical
ISBN : 9780323477734

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Pancreatic Cancer and Periampullary Neoplasms, An Issue of Surgical Clinics of North America, E-Book by Jeffrey M. Hardacre Pdf

This issue of Surgical Clinics of North America, guest edited by Dr. Jeffrey M. Hardacre, is devoted to Pancreatic Cancer and Periampullary Neoplasms. He has assembled expert authors to review the following topics: Genetics of Pancreatic Cancer and its Implication on Therapy; Familial Pancreatic Cancer and Screening of High-risk Individuals; Imaging Evaluation of Pancreatic Cancer; Endoscopic Evaluation in the Work-up of Pancreatic Cancer; Definition and Management of Borderline Resectable Pancreatic Cancer; Techniques of Vascular Resection and Reconstruction in Pancreatic Cancer Surgery; Surgical Therapy for Pancreatic and Periampullary Cancer; Post-Pancreatectomy Complications and Management; Adjuvant and Neoadjuvant Therapy for Resectable Pancreatic and Periampullary Cancer; Management of Locally Advanced Pancreatic Cancer; Management of Metastatic Pancreatic Cancer; Management of Pancreatic Neuroendocrine Tumors; Management of Intraductal Papillary Mucinous Neoplasms; Palliative Care and Surgery in Pancreatic Cancer; Enhanced Recovery Pathways in Pancreatic Cancer; and more!

Author : Manoop S. Bhutani,Matthew H.G. Katz,Anirban Maitra,Joseph M. Herman,Robert A. Wolff
Publisher : Springer Nature
Page : 394 pages
File Size : 53,5 Mb
Release : 2022-10-22
Category : Medical
ISBN : 9783031057243

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Pancreatic Cancer: A Multidisciplinary Approach by Manoop S. Bhutani,Matthew H.G. Katz,Anirban Maitra,Joseph M. Herman,Robert A. Wolff Pdf

This book provides a comprehensive, state-of-the-art overview of pancreatic cancer. The text presents new data about risk factors and genetic predisposition for pancreatic cancer, highlights current screening strategies and preliminary results, and reviews diagnosis and staging of pancreatic cancer, with a focus on imaging evaluations, laparoscopy, endoscopic ultrasound-guided biopsies, and biomarkers. The book also spotlights emerging paradigms in pancreatic cancer management, such as minimally invasive surgical approaches and emerging radiation approaches, and provides valuable insight into the role of nutrition and early integration of supportive/palliative care for pancreatic cancer patients. Written by experts in the field, Pancreatic Cancer: A Multidisciplinary Approach is an invaluable resource for physicians and researchers with an interest in pancreatic cancer.

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 52,8 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Author : Hiroki Yamaue
Publisher : Springer
Page : 260 pages
File Size : 53,5 Mb
Release : 2017-07-19
Category : Medical
ISBN : 9789811024863

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Innovation of Diagnosis and Treatment for Pancreatic Cancer by Hiroki Yamaue Pdf

This collection of chapters describes in detail the latest insights into the evaluation of resectability and neoadjuvant therapy to pancreaticoduodenectomy and distal pancreatectomy for pancreatic cancer. Shedding light on immunotherapy and gene therapy, this volume comprehensively covers treatments and procedures for the disease, allowing surgeons and trainees to gain an overview and explore innovative treatments. It also provides information on various cases using tools such as endoscopic ultrasound, MDCT, PET for diagnosis and laparoscopy and robotic resection methods. Edited and authored by pioneering professionals, Diagnosis and Treatment for Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, surgical oncologist and general surgeons interested in treatment of pancreatic cancer care.

Author : Andrew M. Lowy
Publisher : Clinics: Surgery
Page : 0 pages
File Size : 43,9 Mb
Release : 2010
Category : Medical
ISBN : 1437718795

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Pancreatic cancer by Andrew M. Lowy Pdf

This issue of the Surgical Oncology Clinics will cover the following topics: imaging for pancreatic cancer, EUS staging and novel therapeutics for pancreatic cancer, management of cystic tumors, management of IPMN, laparoscopic surgery for pancreatic tumors, current concepts in the surgical management of pancreatic cancer, management of borderline resectable pancreatic cancer, regionalization of pancreatic surgery, update on adjuvant trials for pancreatic cancer, neoadjuvant therapy for pancreatic cancer, novel targets for pancreatic cancer therapy, and new frontiers in pancreatic cancer.

Author : Hiroyuki Isayama,Yousuke Nakai,Takashi Sasaki
Publisher : Springer Nature
Page : 318 pages
File Size : 54,8 Mb
Release : 2021-07-19
Category : Medical
ISBN : 9789811628702

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Management of Pancreatic Cancer and Cholangiocarcinoma by Hiroyuki Isayama,Yousuke Nakai,Takashi Sasaki Pdf

This comprehensive book presents the latest evidence-based data on pancreatobiliary malignancies, including the epidemiology, examination, treatment and endoscopic management. It explores a range of topics, such as risk factors, detection strategies, and novel treatment approaches like precision medicine and immunotherapy. Although there have been rapid improvements in the management of these diseases, the survival period has not yet reached a satisfactory level. This book will help those doctors needing to share the latest information with the patients and their families. It provides a wealth of practical information to help surgeons, endoscopists and oncologists as well as physicians, basic researchers and professionals at medical device and pharmaceutical companies broaden their understanding of the current treatment and management strategies for pancreatobiliary malignancies.

Author : Jean-Nicolas` Vauthey,Antoine Brouquet
Publisher : Springer Science & Business Media
Page : 266 pages
File Size : 51,6 Mb
Release : 2012-08-31
Category : Medical
ISBN : 9783642160370

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Multidisciplinary Treatment of Hepatocellular Carcinoma by Jean-Nicolas` Vauthey,Antoine Brouquet Pdf

It is now widely accepted that multidisciplinary collaboration and multimodality treatment approaches are important in improving the survival of patients with hepatocellular carcinoma. In this comprehensive textbook, internationally renowned experts in the field present and discuss the various strategies employed in the treatment of the disease. Up-to-date information is provided on the indications for and outcome of a range of treatment options, including surgical resection, liver transplantation, radiofrequency ablation, transarterial chemoembolization, yttrium-90 transarterial radioembolization, and systemic therapy. In addition, important background information is included on biology, pathology, staging, and imaging. This book will be particularly helpful to all professionals and trainees worldwide who have an interest in the diagnosis and treatment of hepatocellular carcinoma.

Author : Owen Abraham
Publisher : Unknown
Page : 0 pages
File Size : 52,7 Mb
Release : 2015-03-16
Category : Electronic
ISBN : 1632410877

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Clinical Management of Pancreatic Cancer by Owen Abraham Pdf

The disease in which cancer cells develop in the glandular organ situated behind the stomach, known as pancreas, is referred to as Pancreatic Cancer. The treatment, clinical processes and risk factors related to the severe disease of pancreatic cancer hav

Author : Isidore Cohn
Publisher : Unknown
Page : 112 pages
File Size : 51,5 Mb
Release : 1981-01-01
Category : Pancreas
ISBN : 0893521337

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Pancreatic Cancer by Isidore Cohn Pdf

Author : Fazlul H. Sarkar,Michael C. Dugan
Publisher : Eaton Publishing Company/Biotechniques Books
Page : 232 pages
File Size : 43,8 Mb
Release : 1998
Category : Medical
ISBN : CHI:56383034

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Pancreatic Cancer by Fazlul H. Sarkar,Michael C. Dugan Pdf