Mass Spectrometry For The Analysis Of Pesticide Residues And Their Metabolites

Author : Despina Tsipi,Helen Botitsi,Anastasios Economou
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 44,8 Mb
Release : 2015-04-27
Category : Science
ISBN : 9781118500170

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Mass Spectrometry for the Analysis of Pesticide Residues and their Metabolites by Despina Tsipi,Helen Botitsi,Anastasios Economou Pdf

Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites. Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in combination with MS for the analysis of pesticides Describes various established and new ionization techniques as well as the main MS platforms, software tools and mass spectral libraries

Author : Horacio Heinzen,Leo M.L. Nollet,Amadeo R. Fernandez-Alba
Publisher : CRC Press
Page : 452 pages
File Size : 54,8 Mb
Release : 2017-10-10
Category : Science
ISBN : 9781482235104

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Multiresidue Methods for the Analysis of Pesticide Residues in Food by Horacio Heinzen,Leo M.L. Nollet,Amadeo R. Fernandez-Alba Pdf

In the last decades the public concern on the pesticide residues content in foods have been steadily rising. The global development of food trade implies that aliments from everywhere in the world can reach the consumer`s table. Therefore, the identification of agricultural practices that employ different pesticides combinations and application rates to protect produce must be characterized, as they left residues that could be noxious to human health. However, the possible number of pesticides (and its metabolites of toxicological relevance) to be found in a specific commodity is almost 1500, and the time needed to analyze them one by one, makes this analytical strategy a unrealistic task. To overcome this problem, the concept of Multi Residue Methods (MRM) for the analysis of pesticide traces have been developed. The advent of new and highly sensitive instrumentation, based in hyphenatedchromatographic systems to coupled mass analyzers (XC (MS/MS) or MSn) permitted simultaneously the identification and the determination of up to hundreds of pesticide residues in a single chromatographic run. Multiresidue Methods for the Analysis of Pesticide Residues in Food presents the analytical procedures developed in the literature, as well as those currently employed in the most advanced laboratories that perform routinely Pesticide Residue Analysis in foods. In addition to these points, the regulations, guidelines and recommendations from the most important regulatory agencies of the world on the topic will be commented and contrasted.

Author : Jose L. Tadeo
Publisher : CRC Press
Page : 380 pages
File Size : 51,7 Mb
Release : 2019-03-04
Category : Science
ISBN : 9781351047067

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Analysis of Pesticides in Food and Environmental Samples, Second Edition by Jose L. Tadeo Pdf

This book provides a critical overview of analytical methods used for the determination of pesticide residues and other contaminants in food and environmental samples by modern instrumental analysis. It contains up-to-date material including recent trends in sample preparation, general methods used for pesticide analysis and quality assurance aspects, and chromatographic and immunoassay methods. The rest of the book describes particular analytical methods used for the determination of pesticides in food and soil, water and air. In addition, the levels of these chemicals found in food, their regulatory aspects and the monitoring of pesticides in the environment are described.

Author : Roberto Romero-González,Antonia Garrido Frenich
Publisher : Elsevier
Page : 360 pages
File Size : 53,7 Mb
Release : 2017-03-07
Category : Science
ISBN : 9780128096482

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Applications in High Resolution Mass Spectrometry by Roberto Romero-González,Antonia Garrido Frenich Pdf

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

Author : F. Hernández,M. Ibáñez
Publisher : Elsevier Inc. Chapters
Page : 688 pages
File Size : 40,7 Mb
Release : 2013-01-08
Category : Science
ISBN : 9780128071175

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Liquid Chromatography by F. Hernández,M. Ibáñez Pdf

Pesticide residue analysis is a specialized field of modern analytical chemistry, where the role of LC–MS is of great importance. A highly reliable determination, including both quantification and identification, of pesticide residues in food is required nowadays because of the strict international regulations on maximum residue Limits. The increasing interest of including metabolites in analyses comes from the inclusion of pesticide-related compounds within the residue definition. The polar character of most pesticides used at present and their metabolites make LC coupled to tandem MS the technique of choice for the great majority of compounds. Thus, LC–MS/MS with a triple-quadrupole (QqQ) analyzer is highly appropriate for developing multiresidue methods, where up to 200–300 analytes can be simultaneously determined. It can also be efficiently applied to solve analytical problems associated with some problematic pesticides, such as those present as ionic compounds in the samples, which have to be determined with more specific LC–MS/MS methods. High-resolution MS using modern analyzers like time of flight or Orbitrap offers interesting features for wide-scope screening of pesticides and metabolites in food, due to their mass accuracy capabilities, with the advantage that a retrospective analysis is feasible at any time to search for other compounds that were not included in the first analysis.

Author : Jose L. Tadeo
Publisher : CRC Press
Page : 384 pages
File Size : 41,7 Mb
Release : 2008-02-07
Category : Science
ISBN : 1420007750

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Analysis of Pesticides in Food and Environmental Samples by Jose L. Tadeo Pdf

Developing safety regulations for pesticides used around the world—in excess of 2.5 million tons annually—requires reliable analytical methods for assessing their impact in food and in the environment. Analysis of Pesticides in Food and Environmental Samples presents the most effective techniques for analyzing pesticide residues and other chemical contaminants in foods as well as in soil, water, and air. Renowned Scientists Report New Data and Advances in the Field The book introduces sample preparation, extraction, and analytical methods specific to each sample type, including foods from vegetal and animal origin. Other chapters discuss important aspects of quality assurance and the applicability of hyphenated analytical techniques. In addition to a practical chapter on the use of biosensors and immunoassays for monitoring and gathering exposure data, the book addresses regulatory aspects and presents current data on the levels of pesticides found in food and environmental matrices. Latest Methods Help Scientists Develop Safer, More Effective Pesticides Analysis of Pesticides in Food and Environmental Samples enables scientists to measure and predict the behavior and toxicity of pesticides with a higher degree of accuracy. The methodologies and insight in this timely work will contribute to the development of more effective, less toxic pesticides as well as better safety regulations.

Author : Tomasz Tuzimski,Joseph Sherma
Publisher : CRC Press
Page : 582 pages
File Size : 43,7 Mb
Release : 2015-12-01
Category : Science
ISBN : 9781498766548

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High Performance Liquid Chromatography in Pesticide Residue Analysis by Tomasz Tuzimski,Joseph Sherma Pdf

HPLC is the principal separation technique for identification of the pesticides in environmental samples and for quantitative analysis of analytes. At each stage of the HPLC procedure, the chromatographer should possess both the practical and theoretical skills required to perform HPLC experiments correctly and to obtain reliable, repeatable, and reproducible results. Developed to serve as a detailed practical guide, High Performance Liquid Chromatography in Pesticide Residue Analysis is a comprehensive source of information and training on state-of-the-art pesticide residue methods performed with the aid of HPLC. The book presents the pros and cons of HPLC as a flexible and versatile separation and analysis tool with multiple purposes and advantages in investigations of pesticides for food and plant drugs standardization, promotion of health, protection of new herbal medicines, and more.

Author : José L. Martínez Vidal
Publisher : Springer Science & Business Media
Page : 491 pages
File Size : 46,5 Mb
Release : 2007-10-26
Category : Science
ISBN : 9781592599295

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Pesticide Protocols by José L. Martínez Vidal Pdf

A comprehensive collection of robust methods for the detection of pesticide compounds or their metabolites useful in food, environmental, and biological monitoring, and in studies of exposure via food, water, air, and the skin or lungs. The readily reproducible methods range from gas and liquid chromatography coupled to mass spectrometry detection and other classic detectors, to capillary electrophoresis and immunochemical or radioimmunoassay methods. The authors have focused on extraction and cleanup procedures, in order to develop and optimize more fullyautomated and miniaturized methods, including solid-phase extraction, solid-phase microextraction, microwave-assisted extraction, and on-line tandem liquid chromatography (LC/LC) trace enrichment, among others. The protocols offer step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Author : H. Anson Moye
Publisher : John Wiley & Sons
Page : 488 pages
File Size : 47,7 Mb
Release : 1981-02-02
Category : Science
ISBN : UCAL:B4456171

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Analysis of Pesticide Residues by H. Anson Moye Pdf

A comprehensive guide to the latest techniques and applications of pesticide trace analysis. Methods covered include gas, thin layer, and high-performance liquid chromatography, along with their applications in the analysis of chlorinated hydrocarbons, acidic herbicides, organophosphates, carbamates, and insect pheromones and hormones. Includes a special chapter on residue data requirements of government agencies.

Author : A.R. Fernandez Alba
Publisher : Elsevier
Page : 510 pages
File Size : 46,5 Mb
Release : 2004-12-11
Category : Science
ISBN : 9780080454405

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Chromatographic-Mass Spectrometric Food Analysis for Trace Determination of Pesticide Residues by A.R. Fernandez Alba Pdf

The trace determination of pesticides continues to be a topic for analytical chemists working in research centres, government and universities. With four chapters devoted to chromatography-mass spectrometry methods, readers are able to understand the analytical basis, technical characteristics and possibilities to evaluate pesticides in food by gas chromatography (GC) and liquid chromatography (LC) mass spectrometry. The book also provides a well-defined and critical compilation of the sample treatment and clean-up procedures, as well as injection techniques applied in GC and LC food analysis. Finally the book deals with aspects related to analytical quality control requirements for pesticide residues, in addition to pesticide regulation aspects. * Contains specific chapters devoted to chromatography-mass spectrometry methods * Provides a well-defined and critical compilation of the sample treatment and clean-up procedures * Contains aspects related to analytical quality control requirements for pesticide residues

Author : W. George Fong,H. Anson Moye,James N. Seiber,John P. Toth
Publisher : John Wiley & Sons
Page : 389 pages
File Size : 41,7 Mb
Release : 1999-01-29
Category : Science
ISBN : 9780471574002

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Pesticide Residues in Foods by W. George Fong,H. Anson Moye,James N. Seiber,John P. Toth Pdf

Advances in analytical chemistry methodology now allow us to detect the most minute trace amounts of pesticides. As this capacity grows, so does public concern about toxic contamination, resulting in stricter government regulations and a growing demand for even more sensitive, precise, and reliable analysis. Addressing the interplay between regulations and the development of analytical technology, this volume presents the first unified treatment of the regulatory and analytical aspects of pesticide residues. Current regulations, existing and emerging methodologies, state-of-the-art instrumentation, and the basic science of analyzing for pesticides in food and other environmental media are all covered. The book provides step-by-step guidelines to analytical techniques, along with real-world examples from the latest research-showing the reader how to analyze minute traces of pesticides quickly and accurately, using both highly sophisticated and basic, less sensitive techniques. Many safety issues are explored in depth, as are the regulatory aspects of pesticide registration, residue analysis, exposure monitoring, risk assessment, and tolerance enforcement. Timely, authoritative, and practical throughout, Pesticide Residues in Foods is an invaluable reference for analytical chemists and laboratory managers everywhere-in industry, agriculture, environmental sciences, research, and instrument manufacturing-and for anyone with an interest in the broader environmental, agricultural, and consumer-related implications of pesticide use. An invaluable resource for analytical chemists and laboratory managers, Pesticide Residues in Foods provides a complete overview of the theory, practice, and regulatory aspects of pesticide residue analysis today, including: * All regulatory issues, from risk assessment and tolerance to data-quality requirements to laboratory accreditation standards * State-of-the-art methodologies and instrumentation, including high- performance liquid chromatography and mass spectrometry * The application of analytical technology to "green chemistry," such as the reduction of solvents and toxic reagents in the laboratory * Novel solutions to the old problem of keeping the food supply safe from harmful levels of pesticides * Ample examples to help analytical chemists select the most appropriate method for a given residue analysis * Easy-to-use tables and figures throughout the text

Author : Council on Environmental Quality (U.S.). Federal Working Group on Pest Management. Monitoring Panel
Publisher : Unknown
Page : 80 pages
File Size : 51,9 Mb
Release : 1975
Category : Environmental monitoring
ISBN : UOM:39015049060968

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Guidelines on Analytical Methodology for Pesticide Residue Monitoring by Council on Environmental Quality (U.S.). Federal Working Group on Pest Management. Monitoring Panel Pdf

Author : Guo-Fang Pang
Publisher : Academic Press
Page : 880 pages
File Size : 44,9 Mb
Release : 2018-06-29
Category : Science
ISBN : 9780128141687

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Analytical Methods for Food Safety by Mass Spectrometry by Guo-Fang Pang Pdf

Analytical Methods for Food Safety by Mass Spectrometry, Volume One: Pesticides systematically introduces the Pesticide and Veterinary Drug Multiresidues Analytical Methods. Volume One includes discussions on 20 pesticide multiresidues chromatic-MS (GC-MS and LC-MS/MS) analytical techniques that have the capability of detecting over 800 pesticides and chemicals in 10 categories of agricultural products, including fruits, vegetables, grains, teas, Chinese medicinal herbs, edible fungus mushrooms, fruit and vegetable juices, animal tissues, aquatic products, raw milk and milk powders, and drinkable water. This book also includes chromatic-MS analytical parameters, linear equations and GPC chromatic behavior parameters for over 800 pesticides. This valuable book can be used as reference for not only university students, but also technical personnel of different specialties who are engaged with study and applications, such as food safety, agricultural environment protection, pesticide development, and utilization in scientific research units, institutions and quality inspection organizations. Provides the chromatic-MS analytical technique for over 1000 commonly-used veterinary and pesticide residues Covers a large varieties of target compounds, including over 800 pesticides (organophosphorus, organochlorine, carbamate, pyrethroids) and over 200 veterinary drugs, including Fluoroquinolone, Sulfonamides, Chloramphenicol, Nitrofurans, Tetracyclines, Nitroimidazole, β-lactams, Quinoxaline, Benzimidazole, β-Adrenoceptor agonists, Aminoglycoside, and more Includes the latest information on sophisticated pre-treatment techniques with a single sample pre-treatment and simultaneous detection by GC-MS and LC-MS/MS

Author : Federal Working Group on Pest Management
Publisher : Unknown
Page : 76 pages
File Size : 52,9 Mb
Release : 1975
Category : Pesticides
ISBN : MINN:31951T002079438

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Guidelines on Analytical Methodology for Pesticide Residue Monitoring by Federal Working Group on Pest Management Pdf

Author : Leo M.L. Nollet,Hamir S. Rathore
Publisher : CRC Press
Page : 628 pages
File Size : 44,7 Mb
Release : 2016-04-19
Category : Science
ISBN : 9781420082470

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Handbook of Pesticides by Leo M.L. Nollet,Hamir S. Rathore Pdf

This handbook provides a systematic description of the principles, procedures, and technology of the modern analytical techniques used in the detection, extraction, clean up, and determination of pesticide residues present in the environment. This book provides the historical background of pesticides and emerging trends in pesticide regulation. The