Mathematical Concepts And Methods In Modern Biology

Author : Raina Robeva,Terrell Hodge
Publisher : Academic Press
Page : 372 pages
File Size : 43,9 Mb
Release : 2013-02-26
Category : Mathematics
ISBN : 9780124157934

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Mathematical Concepts and Methods in Modern Biology by Raina Robeva,Terrell Hodge Pdf

Mathematical Concepts and Methods in Modern Biology offers a quantitative framework for analyzing, predicting, and modulating the behavior of complex biological systems. The book presents important mathematical concepts, methods and tools in the context of essential questions raised in modern biology. Designed around the principles of project-based learning and problem-solving, the book considers biological topics such as neuronal networks, plant population growth, metabolic pathways, and phylogenetic tree reconstruction. The mathematical modeling tools brought to bear on these topics include Boolean and ordinary differential equations, projection matrices, agent-based modeling and several algebraic approaches. Heavy computation in some of the examples is eased by the use of freely available open-source software. Features self-contained chapters with real biological research examples using freely available computational tools Spans several mathematical techniques at basic to advanced levels Offers broad perspective on the uses of algebraic geometry/polynomial algebra in molecular systems biology

Author : Raina Robeva
Publisher : Academic Press
Page : 382 pages
File Size : 44,5 Mb
Release : 2015-05-09
Category : Mathematics
ISBN : 9780128012710

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Algebraic and Discrete Mathematical Methods for Modern Biology by Raina Robeva Pdf

Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. Examines significant questions in modern biology and their mathematical treatments Presents important mathematical concepts and tools in the context of essential biology Features material of interest to students in both mathematics and biology Presents chapters in modular format so coverage need not follow the Table of Contents Introduces projects appropriate for undergraduate research Utilizes freely accessible software for visualization, simulation, and analysis in modern biology Requires no calculus as a prerequisite Provides a complete Solutions Manual Features a companion website with supplementary resources

Author : Raina Robeva,James R. Kirkwood,Robin Lee Davies,Leon Farhy,Boris P. Kovatchev,Martin Straume,Michael L. Johnson
Publisher : Academic Press
Page : 480 pages
File Size : 45,9 Mb
Release : 2007-08-28
Category : Mathematics
ISBN : 0080550991

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An Invitation to Biomathematics by Raina Robeva,James R. Kirkwood,Robin Lee Davies,Leon Farhy,Boris P. Kovatchev,Martin Straume,Michael L. Johnson Pdf

Essential for all biology and biomathematics courses, this textbook provides students with a fresh perspective of quantitative techniques in biology in a field where virtually any advance in the life sciences requires a sophisticated mathematical approach. An Invitation to Biomathematics, expertly written by a team of experienced educators, offers students a solid understanding of solving biological problems with mathematical applications. This text succeeds in enabling students to truly experience advancements made in biology through mathematical models by containing computer-based hands-on laboratory projects with emphasis on model development, model validation, and model refinement. The supplementary work, Laboratory Manual of Biomathematics is available separately ISBN 0123740223, or as a set ISBN: 0123740290) * Provides a complete guide for development of quantification skills crucial for applying mathematical methods to biological problems * Includes well-known examples from across disciplines in the life sciences including modern biomedical research * Explains how to use data sets or dynamical processes to build mathematical models * Offers extensive illustrative materials * Written in clear and easy-to-follow language without assuming a background in math or biology * A laboratory manual is available for hands-on, computer-assisted projects based on material covered in the text

Author : Raina Robeva,Matthew Macauley
Publisher : Academic Press
Page : 434 pages
File Size : 50,7 Mb
Release : 2018-10-08
Category : Mathematics
ISBN : 9780128140697

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Algebraic and Combinatorial Computational Biology by Raina Robeva,Matthew Macauley Pdf

Algebraic and Combinatorial Computational Biology introduces students and researchers to a panorama of powerful and current methods for mathematical problem-solving in modern computational biology. Presented in a modular format, each topic introduces the biological foundations of the field, covers specialized mathematical theory, and concludes by highlighting connections with ongoing research, particularly open questions. The work addresses problems from gene regulation, neuroscience, phylogenetics, molecular networks, assembly and folding of biomolecular structures, and the use of clustering methods in biology. A number of these chapters are surveys of new topics that have not been previously compiled into one unified source. These topics were selected because they highlight the use of technique from algebra and combinatorics that are becoming mainstream in the life sciences. Integrates a comprehensive selection of tools from computational biology into educational or research programs Emphasizes practical problem-solving through multiple exercises, projects and spinoff computational simulations Contains scalable material for use in undergraduate and graduate-level classes and research projects Introduces the reader to freely-available professional software Supported by illustrative datasets and adaptable computer code

Author : Raina Robeva,James R. Kirkwood
Publisher : Academic Press
Page : 187 pages
File Size : 48,8 Mb
Release : 2007-08-28
Category : Computers
ISBN : 9780123740229

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Laboratory Manual of Biomathematics by Raina Robeva,James R. Kirkwood Pdf

Laboratory Manual of Biomathematics is a companion to the textbook An Invitation to Biomathematics. This laboratory manual expertly aids students who wish to gain a deeper understanding of solving biological issues with computer programs. It provides hands-on exploration of model development, model validation, and model refinement, enabling students to truly experience advancements made in biology by mathematical models. Each of the projects offered can be used as individual module in traditional biology or mathematics courses such as calculus, ordinary differential equations, elementary probability, statistics, and genetics. Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology . Mathematical topics include Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms. It includes more than 120 exercises derived from ongoing research studies. This text is designed for courses in mathematical biology, undergraduate biology majors, as well as general mathematics. The reader is not expected to have any extensive background in either math or biology. Can be used as a computer lab component of a course in biomathematics or as homework projects for independent student work Biological topics include: Ecology, Toxicology, Microbiology, Epidemiology, Genetics, Biostatistics, Physiology, Cell Biology, and Molecular Biology Mathematical topics include: Discrete and continuous dynamical systems, difference equations, differential equations, probability distributions, statistics, data transformation, risk function, statistics, approximate entropy, periodic components, and pulse-detection algorithms Includes more than 120 exercises derived from ongoing research studies

Author : Erin N. Bodine,Suzanne Lenhart,Louis J. Gross
Publisher : Princeton University Press
Page : 630 pages
File Size : 47,6 Mb
Release : 2014-08-17
Category : Mathematics
ISBN : 9780691150727

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Mathematics for the Life Sciences by Erin N. Bodine,Suzanne Lenhart,Louis J. Gross Pdf

An accessible undergraduate textbook on the essential math concepts used in the life sciences The life sciences deal with a vast array of problems at different spatial, temporal, and organizational scales. The mathematics necessary to describe, model, and analyze these problems is similarly diverse, incorporating quantitative techniques that are rarely taught in standard undergraduate courses. This textbook provides an accessible introduction to these critical mathematical concepts, linking them to biological observation and theory while also presenting the computational tools needed to address problems not readily investigated using mathematics alone. Proven in the classroom and requiring only a background in high school math, Mathematics for the Life Sciences doesn't just focus on calculus as do most other textbooks on the subject. It covers deterministic methods and those that incorporate uncertainty, problems in discrete and continuous time, probability, graphing and data analysis, matrix modeling, difference equations, differential equations, and much more. The book uses MATLAB throughout, explaining how to use it, write code, and connect models to data in examples chosen from across the life sciences. Provides undergraduate life science students with a succinct overview of major mathematical concepts that are essential for modern biology Covers all the major quantitative concepts that national reports have identified as the ideal components of an entry-level course for life science students Provides good background for the MCAT, which now includes data-based and statistical reasoning Explicitly links data and math modeling Includes end-of-chapter homework problems, end-of-unit student projects, and select answers to homework problems Uses MATLAB throughout, and MATLAB m-files with an R supplement are available online Prepares students to read with comprehension the growing quantitative literature across the life sciences A solutions manual for professors and an illustration package is available

Author : Raina S. Robeva
Publisher : Unknown
Page : 453 pages
File Size : 52,7 Mb
Release : 2008
Category : Mathematics
ISBN : 0120887711

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An Invitation to Biomathematics by Raina S. Robeva Pdf

This textbook provides students with a fresh perspective of quantitative techniques in biology in a field where virtually any advance in the life sciences requires a sophisticated mathematical approach. It is written by a team of experienced educators, and offers students a solid understanding of solving biological problems with mathematical applications. It succeeds in enabling students to truly experience advancements made in biology through mathematical models by containing computer-based hands-on laboratory projects with emphasis on model development, model validation, and model refinement.

Author : Glenn Ledder
Publisher : Springer Nature
Page : 377 pages
File Size : 41,7 Mb
Release : 2023-04-13
Category : Mathematics
ISBN : 9783031094545

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Mathematical Modeling for Epidemiology and Ecology by Glenn Ledder Pdf

Mathematical Modeling for Epidemiology and Ecology provides readers with the mathematical tools needed to understand and use mathematical models and read advanced mathematical biology books. It presents mathematics in biological contexts, focusing on the central mathematical ideas and the biological implications, with detailed explanations. The author assumes no mathematics background beyond elementary differential calculus. An introductory chapter on basic principles of mathematical modeling is followed by chapters on empirical modeling and mechanistic modeling. These chapters contain a thorough treatment of key ideas and techniques that are often neglected in mathematics books, such as the Akaike Information Criterion. The second half of the book focuses on analysis of dynamical systems, emphasizing tools to simplify analysis, such as the Routh-Hurwitz conditions and asymptotic analysis. Courses can be focused on either half of the book or thematically chosen material from both halves, such as a course on mathematical epidemiology. The biological content is self-contained and includes many topics in epidemiology and ecology. Some of this material appears in case studies that focus on a single detailed example, and some is based on recent research by the author on vaccination modeling and scenarios from the COVID-19 pandemic. The problem sets feature linked problems where one biological setting appears in multi-step problems that are sorted into the appropriate section, allowing readers to gradually develop complete investigations of topics such as HIV immunology and harvesting of natural resources. Some problems use programs written by the author for Matlab or Octave; these combine with more traditional mathematical exercises to give students a full set of tools for model analysis. Each chapter contains additional case studies in the form of projects with detailed directions. New appendices contain mathematical details on optimization, numerical solution of differential equations, scaling, linearization, and sophisticated use of elementary algebra to simplify problems.

Author : James D. Murray
Publisher : Springer Science & Business Media
Page : 782 pages
File Size : 41,9 Mb
Release : 2013-03-09
Category : Mathematics
ISBN : 9783662085394

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Mathematical Biology by James D. Murray Pdf

Mathematical biology - the use of mathematical ideas and models in the biosciences - is a fast growing, very exciting and increasingly important inderdisciplinary field. This textbook is an account of some of the major techniques and models used and of some genuine practical applications drawn from current areas of research interest in, for example, population ecology, developmental biology, physiology, epidemiology and evolution. It provides the reader with a thorough background, sufficient to start genuine interdisciplinary collaborative reserach with biomedical scientists.

Author : Gerda de Vries,Thomas Hillen,Mark Lewis,Johannes M?ller,Birgitt Sch?nfisch
Publisher : SIAM
Page : 307 pages
File Size : 53,7 Mb
Release : 2006-07-01
Category : Mathematics
ISBN : 9780898716122

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A Course in Mathematical Biology by Gerda de Vries,Thomas Hillen,Mark Lewis,Johannes M?ller,Birgitt Sch?nfisch Pdf

This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

Author : Jürgen Jost
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 54,5 Mb
Release : 2014-02-13
Category : Mathematics
ISBN : 9781447163534

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Mathematical Methods in Biology and Neurobiology by Jürgen Jost Pdf

Mathematical models can be used to meet many of the challenges and opportunities offered by modern biology. The description of biological phenomena requires a range of mathematical theories. This is the case particularly for the emerging field of systems biology. Mathematical Methods in Biology and Neurobiology introduces and develops these mathematical structures and methods in a systematic manner. It studies: • discrete structures and graph theory • stochastic processes • dynamical systems and partial differential equations • optimization and the calculus of variations. The biological applications range from molecular to evolutionary and ecological levels, for example: • cellular reaction kinetics and gene regulation • biological pattern formation and chemotaxis • the biophysics and dynamics of neurons • the coding of information in neuronal systems • phylogenetic tree reconstruction • branching processes and population genetics • optimal resource allocation • sexual recombination • the interaction of species. Written by one of the most experienced and successful authors of advanced mathematical textbooks, this book stands apart for the wide range of mathematical tools that are featured. It will be useful for graduate students and researchers in mathematics and physics that want a comprehensive overview and a working knowledge of the mathematical tools that can be applied in biology. It will also be useful for biologists with some mathematical background that want to learn more about the mathematical methods available to deal with biological structures and data.

Author : Haitao Li,Guodong Zhao,Peilian Guo
Publisher : CRC Press
Page : 286 pages
File Size : 52,8 Mb
Release : 2018-05-11
Category : Mathematics
ISBN : 9781351368292

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Analysis and Control of Finite-Valued Systems by Haitao Li,Guodong Zhao,Peilian Guo Pdf

A comprehensive work in finite-value systems that covers the latest achievements using the semi-tensor product method, on various kinds of finite-value systems. These results occupy the highest position in the analysis and control of this field. It not only covers all aspects of research in finite-value systems, but also presents the mathematical derivation for each conclusion in depth. The book contains examples to provide a better understanding of the practical applications of finite-value systems. It will serve as a textbook for graduate students of Cybernetics, Mathematical, and Biology, and a reference for readers interested in the theory of finite-value systems.

Author : Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach
Publisher : John Wiley & Sons
Page : 486 pages
File Size : 40,7 Mb
Release : 2008-07-15
Category : Medical
ISBN : 9783527604883

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Systems Biology in Practice by Edda Klipp,Ralf Herwig,Axel Kowald,Christoph Wierling,Hans Lehrach Pdf

Presenting the main concepts, this book leads students as well as advanced researchers from different disciplines to an understanding of current ideas in the complex field of comprehensive experimental investigation of biological objects, analysis of data, development of models, simulation, and hypothesis generation. It provides readers with guidance on how a specific complex biological question may be tackled: - How to formulate questions that can be answered - Which experiments to perform - Where to find information in databases and on the Internet - What kinds of models are appropriate - How to use simulation tools - What can be learned from the comparison of experimental data and modeling results - How to make testable predictions. The authors demonstrate how mathematical concepts can illuminate the principles underlying biology at a genetic, molecular, cellular and even organism level, and how to use mathematical tools for analysis and prediction.

Author : SUSAN. HUBER HOLMES (WOLFGANG.),Wolfgang Huber
Publisher : Cambridge University Press
Page : 407 pages
File Size : 45,7 Mb
Release : 2018
Category : Electronic
ISBN : 9781108427029

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Modern Statistics for Modern Biology by SUSAN. HUBER HOLMES (WOLFGANG.),Wolfgang Huber Pdf

Author : Alessandra Rogato,Valeria Zazzu,Mario Guarracino
Publisher : Springer
Page : 148 pages
File Size : 42,8 Mb
Release : 2016-11-03
Category : Mathematics
ISBN : 9783319457239

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Dynamics of Mathematical Models in Biology by Alessandra Rogato,Valeria Zazzu,Mario Guarracino Pdf

This volume focuses on contributions from both the mathematics and life science community surrounding the concepts of time and dynamicity of nature, two significant elements which are often overlooked in modeling process to avoid exponential computations. The book is divided into three distinct parts: dynamics of genomes and genetic variation, dynamics of motifs, and dynamics of biological networks. Chapters included in dynamics of genomes and genetic variation analyze the molecular mechanisms and evolutionary processes that shape the structure and function of genomes and those that govern genome dynamics. The dynamics of motifs portion of the volume provides an overview of current methods for motif searching in DNA, RNA and proteins, a key process to discover emergent properties of cells, tissues, and organisms. The part devoted to the dynamics of biological networks covers networks aptly discusses networks in complex biological functions and activities that interpret processes in cells. Moreover, chapters in this section examine several mathematical models and algorithms available for integration, analysis, and characterization. Once life scientists began to produce experimental data at an unprecedented pace, it become clear that mathematical models were necessary to interpret data, to structure information with the aim to unveil biological mechanisms, discover results, and make predictions. The second annual “Bringing Maths to Life” workshop held in Naples, Italy October 2015, enabled a bi-directional flow of ideas from and international group of mathematicians and biologists. The venue allowed mathematicians to introduce novel algorithms, methods, and software that may be useful to model aspects of life science, and life scientists posed new challenges for mathematicians.