Mathematical Methods In Biology

Author : J. David Logan,William Wolesensky
Publisher : John Wiley & Sons
Page : 437 pages
File Size : 54,8 Mb
Release : 2009-08-17
Category : Science
ISBN : 9780470525876

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Mathematical Methods in Biology by J. David Logan,William Wolesensky Pdf

A one-of-a-kind guide to using deterministic and probabilistic methods for solving problems in the biological sciences Highlighting the growing relevance of quantitative techniques in scientific research, Mathematical Methods in Biology provides an accessible presentation of the broad range of important mathematical methods for solving problems in the biological sciences. The book reveals the growing connections between mathematics and biology through clear explanations and specific, interesting problems from areas such as population dynamics, foraging theory, and life history theory. The authors begin with an introduction and review of mathematical tools that are employed in subsequent chapters, including biological modeling, calculus, differential equations, dimensionless variables, and descriptive statistics. The following chapters examine standard discrete and continuous models using matrix algebra as well as difference and differential equations. Finally, the book outlines probability, statistics, and stochastic methods as well as material on bootstrapping and stochastic differential equations, which is a unique approach that is not offered in other literature on the topic. In order to demonstrate the application of mathematical methods to the biological sciences, the authors provide focused examples from the field of theoretical ecology, which serve as an accessible context for study while also demonstrating mathematical skills that are applicable to many other areas in the life sciences. The book's algorithms are illustrated using MATLAB®, but can also be replicated using other software packages, including R, Mathematica®, and Maple; however, the text does not require any single computer algebra package. Each chapter contains numerous exercises and problems that range in difficulty, from the basic to more challenging, to assist readers with building their problem-solving skills. Selected solutions are included at the back of the book, and a related Web site features supplemental material for further study. Extensively class-tested to ensure an easy-to-follow format, Mathematical Methods in Biology is an excellent book for mathematics and biology courses at the upper-undergraduate and graduate levels. It also serves as a valuable reference for researchers and professionals working in the fields of biology, ecology, and biomathematics.

Author : Jürgen Jost
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 46,6 Mb
Release : 2014-02-13
Category : Mathematics
ISBN : 9781447163534

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Mathematical Methods in Biology and Neurobiology by Jürgen Jost Pdf

Mathematical models can be used to meet many of the challenges and opportunities offered by modern biology. The description of biological phenomena requires a range of mathematical theories. This is the case particularly for the emerging field of systems biology. Mathematical Methods in Biology and Neurobiology introduces and develops these mathematical structures and methods in a systematic manner. It studies: • discrete structures and graph theory • stochastic processes • dynamical systems and partial differential equations • optimization and the calculus of variations. The biological applications range from molecular to evolutionary and ecological levels, for example: • cellular reaction kinetics and gene regulation • biological pattern formation and chemotaxis • the biophysics and dynamics of neurons • the coding of information in neuronal systems • phylogenetic tree reconstruction • branching processes and population genetics • optimal resource allocation • sexual recombination • the interaction of species. Written by one of the most experienced and successful authors of advanced mathematical textbooks, this book stands apart for the wide range of mathematical tools that are featured. It will be useful for graduate students and researchers in mathematics and physics that want a comprehensive overview and a working knowledge of the mathematical tools that can be applied in biology. It will also be useful for biologists with some mathematical background that want to learn more about the mathematical methods available to deal with biological structures and data.

Author : Gerda de Vries,Thomas Hillen,Mark Lewis,Johannes M?ller,Birgitt Sch?nfisch
Publisher : SIAM
Page : 307 pages
File Size : 41,6 Mb
Release : 2006-07-01
Category : Mathematics
ISBN : 9780898716122

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A Course in Mathematical Biology by Gerda de Vries,Thomas Hillen,Mark Lewis,Johannes M?ller,Birgitt Sch?nfisch Pdf

This is the only book that teaches all aspects of modern mathematical modeling and that is specifically designed to introduce undergraduate students to problem solving in the context of biology. Included is an integrated package of theoretical modeling and analysis tools, computational modeling techniques, and parameter estimation and model validation methods, with a focus on integrating analytical and computational tools in the modeling of biological processes. Divided into three parts, it covers basic analytical modeling techniques; introduces computational tools used in the modeling of biological problems; and includes various problems from epidemiology, ecology, and physiology. All chapters include realistic biological examples, including many exercises related to biological questions. In addition, 25 open-ended research projects are provided, suitable for students. An accompanying Web site contains solutions and a tutorial for the implementation of the computational modeling techniques. Calculations can be done in modern computing languages such as Maple, Mathematica, and MATLAB?.

Author : Raina Robeva
Publisher : Academic Press
Page : 382 pages
File Size : 54,6 Mb
Release : 2015-05-09
Category : Mathematics
ISBN : 9780128012710

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Algebraic and Discrete Mathematical Methods for Modern Biology by Raina Robeva Pdf

Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. Examines significant questions in modern biology and their mathematical treatments Presents important mathematical concepts and tools in the context of essential biology Features material of interest to students in both mathematics and biology Presents chapters in modular format so coverage need not follow the Table of Contents Introduces projects appropriate for undergraduate research Utilizes freely accessible software for visualization, simulation, and analysis in modern biology Requires no calculus as a prerequisite Provides a complete Solutions Manual Features a companion website with supplementary resources

Author : Raina Robeva,Terrell Hodge
Publisher : Academic Press
Page : 372 pages
File Size : 54,7 Mb
Release : 2013-02-26
Category : Mathematics
ISBN : 9780124157934

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Mathematical Concepts and Methods in Modern Biology by Raina Robeva,Terrell Hodge Pdf

Mathematical Concepts and Methods in Modern Biology offers a quantitative framework for analyzing, predicting, and modulating the behavior of complex biological systems. The book presents important mathematical concepts, methods and tools in the context of essential questions raised in modern biology. Designed around the principles of project-based learning and problem-solving, the book considers biological topics such as neuronal networks, plant population growth, metabolic pathways, and phylogenetic tree reconstruction. The mathematical modeling tools brought to bear on these topics include Boolean and ordinary differential equations, projection matrices, agent-based modeling and several algebraic approaches. Heavy computation in some of the examples is eased by the use of freely available open-source software. Features self-contained chapters with real biological research examples using freely available computational tools Spans several mathematical techniques at basic to advanced levels Offers broad perspective on the uses of algebraic geometry/polynomial algebra in molecular systems biology

Author : Johannes Müller,Christina Kuttler
Publisher : Springer
Page : 711 pages
File Size : 43,8 Mb
Release : 2015-08-13
Category : Mathematics
ISBN : 9783642272516

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Methods and Models in Mathematical Biology by Johannes Müller,Christina Kuttler Pdf

This book developed from classes in mathematical biology taught by the authors over several years at the Technische Universität München. The main themes are modeling principles, mathematical principles for the analysis of these models and model-based analysis of data. The key topics of modern biomathematics are covered: ecology, epidemiology, biochemistry, regulatory networks, neuronal networks and population genetics. A variety of mathematical methods are introduced, ranging from ordinary and partial differential equations to stochastic graph theory and branching processes. A special emphasis is placed on the interplay between stochastic and deterministic models.

Author : Frank Charles Hoppensteadt
Publisher : Cambridge University Press
Page : 162 pages
File Size : 47,9 Mb
Release : 1982-02-26
Category : Mathematics
ISBN : 052128256X

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Mathematical Methods of Population Biology by Frank Charles Hoppensteadt Pdf

An introduction to mathematical methods used in the study of population phenomena including models of total population and population age structure, models of random population events presented in terms of Markov chains, and methods used to uncover qualitative behavior of more complicated difference equations.

Author : Jacek Banasiak,Mirosław Lachowicz
Publisher : Springer Science & Business
Page : 285 pages
File Size : 45,5 Mb
Release : 2014-04-19
Category : Mathematics
ISBN : 9783319051406

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Methods of Small Parameter in Mathematical Biology by Jacek Banasiak,Mirosław Lachowicz Pdf

This monograph presents new tools for modeling multiscale biological processes. Natural processes are usually driven by mechanisms widely differing from each other in the time or space scale at which they operate and thus should be described by appropriate multiscale models. However, looking at all such scales simultaneously is often infeasible, costly, and provides information that is redundant for a particular application. Hence, there has been a growing interest in providing a more focused description of multiscale processes by aggregating variables in a way that is relevant to the purpose at hand and preserves the salient features of the dynamics. Many ad hoc methods have been devised, and the aim of this book is to present a systematic way of deriving the so-called limit equations for such aggregated variables and ensuring that the coefficients of these equations encapsulate the relevant information from the discarded levels of description. Since any approximation is only valid if an estimate of the incurred error is available, the tools the authors describe allow for proving that the solutions to the original multiscale family of equations converge to the solution of the limit equation if the relevant parameter converges to its critical value. The chapters are arranged according to the mathematical complexity of the analysis, from systems of ordinary linear differential equations, through nonlinear ordinary differential equations, to linear and nonlinear partial differential equations. Many chapters begin with a survey of mathematical techniques needed for the analysis. All problems discussed in this book belong to the class of singularly perturbed problems; that is, problems in which the structure of the limit equation is significantly different from that of the multiscale model. Such problems appear in all areas of science and can be attacked using many techniques. Methods of Small Parameter in Mathematical Biology will appeal to senior undergraduate and graduate students in applied and biomathematics, as well as researchers specializing in differential equations and asymptotic analysis.

Author : Leah Edelstein-Keshet
Publisher : SIAM
Page : 629 pages
File Size : 43,7 Mb
Release : 1988-01-01
Category : Mathematics
ISBN : 0898719143

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Mathematical Models in Biology by Leah Edelstein-Keshet Pdf

Mathematical Models in Biology is an introductory book for readers interested in biological applications of mathematics and modeling in biology. A favorite in the mathematical biology community, it shows how relatively simple mathematics can be applied to a variety of models to draw interesting conclusions. Connections are made between diverse biological examples linked by common mathematical themes. A variety of discrete and continuous ordinary and partial differential equation models are explored. Although great advances have taken place in many of the topics covered, the simple lessons contained in this book are still important and informative. Audience: the book does not assume too much background knowledge--essentially some calculus and high-school algebra. It was originally written with third- and fourth-year undergraduate mathematical-biology majors in mind; however, it was picked up by beginning graduate students as well as researchers in math (and some in biology) who wanted to learn about this field.

Author : John David Logan,William R. Wolesensky
Publisher : John Wiley & Sons
Page : 417 pages
File Size : 40,8 Mb
Release : 2009
Category : Science
ISBN : 0470528931

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Mathematical Methods in Biology by John David Logan,William R. Wolesensky Pdf

The last several years has witnessed a revolution in the connections between mathematics and biology, and this book differs from most others on the topic in that it covers both deterministic and probabilistic models. The first chapter is a long introduction and review of ideas about biological modeling, calculus, differential equations, dimensionless variables, and descriptive statistics. The next three chapters examine standard discrete and continuous models using difference and differential equations, and matrix algebra (there is a long appendix in Chapter 3 on matrices). The final three chapters cover probability, statistics, and stochastic processes, including bootstrap methods and stochastic differential equations. The book focuses mostly in one area of the life sciences, namely, theoretical ecology. Ecology has become extremely quantitative, and the mathematical techniques used in ecology are applicable to most other areas in the life sciences. Ecology provides an especially accessible context for study by mathematics majors. Moreover, the authors chose ecology for the book's motivations and examples in light of their own interests and research in the area. Additional topical coverage includes an introduction to ecological modeling, population dynamics for single species, structure and interacting populations, interactions in continuous time, concepts of probability, statistical inference, and stochastic processes.

Author : Jurgen Jost
Publisher : Unknown
Page : 238 pages
File Size : 43,9 Mb
Release : 2014-03-31
Category : Electronic
ISBN : 1447163540

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Mathematical Methods in Biology and Neurobiology by Jurgen Jost Pdf

Author : Lee A. Segel,Leah Edelstein-Keshet
Publisher : SIAM
Page : 435 pages
File Size : 47,5 Mb
Release : 2013-05-09
Category : Science
ISBN : 9781611972498

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A Primer in Mathematical Models in Biology by Lee A. Segel,Leah Edelstein-Keshet Pdf

A textbook on mathematical modelling techniques with powerful applications to biology, combining theoretical exposition with exercises and examples.

Author : Brian P. Ingalls
Publisher : MIT Press
Page : 423 pages
File Size : 40,5 Mb
Release : 2022-06-07
Category : Science
ISBN : 9780262545822

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Mathematical Modeling in Systems Biology by Brian P. Ingalls Pdf

An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.

Author : Mazen Shahin
Publisher : John Wiley & Sons
Page : 304 pages
File Size : 42,9 Mb
Release : 2013-12-24
Category : Science
ISBN : 9781118548530

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Explorations of Mathematical Models in Biology with MATLAB by Mazen Shahin Pdf

Explore and analyze the solutions of mathematical models from diverse disciplines As biology increasingly depends on data, algorithms, and models, it has become necessary to use a computing language, such as the user-friendly MATLAB, to focus more on building and analyzing models as opposed to configuring tedious calculations. Explorations of Mathematical Models in Biology with MATLAB provides an introduction to model creation using MATLAB, followed by the translation, analysis, interpretation, and observation of the models. With an integrated and interdisciplinary approach that embeds mathematical modeling into biological applications, the book illustrates numerous applications of mathematical techniques within biology, ecology, and environmental sciences. Featuring a quantitative, computational, and mathematical approach, the book includes: Examples of real-world applications, such as population dynamics, genetics, drug administration, interacting species, and the spread of contagious diseases, to showcase the relevancy and wide applicability of abstract mathematical techniques Discussion of various mathematical concepts, such as Markov chains, matrix algebra, eigenvalues, eigenvectors, first-order linear difference equations, and nonlinear first-order difference equations Coverage of difference equations to model a wide range of real-life discrete time situations in diverse areas as well as discussions on matrices to model linear problems Solutions to selected exercises and additional MATLAB codes Explorations of Mathematical Models in Biology with MATLAB is an ideal textbook for upper-undergraduate courses in mathematical models in biology, theoretical ecology, bioeconomics, forensic science, applied mathematics, and environmental science. The book is also an excellent reference for biologists, ecologists, mathematicians, biomathematicians, and environmental and resource economists.

Author : Sarah P. Otto,Troy Day
Publisher : Princeton University Press
Page : 745 pages
File Size : 40,6 Mb
Release : 2011-09-19
Category : Science
ISBN : 9781400840915

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A Biologist's Guide to Mathematical Modeling in Ecology and Evolution by Sarah P. Otto,Troy Day Pdf

Thirty years ago, biologists could get by with a rudimentary grasp of mathematics and modeling. Not so today. In seeking to answer fundamental questions about how biological systems function and change over time, the modern biologist is as likely to rely on sophisticated mathematical and computer-based models as traditional fieldwork. In this book, Sarah Otto and Troy Day provide biology students with the tools necessary to both interpret models and to build their own. The book starts at an elementary level of mathematical modeling, assuming that the reader has had high school mathematics and first-year calculus. Otto and Day then gradually build in depth and complexity, from classic models in ecology and evolution to more intricate class-structured and probabilistic models. The authors provide primers with instructive exercises to introduce readers to the more advanced subjects of linear algebra and probability theory. Through examples, they describe how models have been used to understand such topics as the spread of HIV, chaos, the age structure of a country, speciation, and extinction. Ecologists and evolutionary biologists today need enough mathematical training to be able to assess the power and limits of biological models and to develop theories and models themselves. This innovative book will be an indispensable guide to the world of mathematical models for the next generation of biologists. A how-to guide for developing new mathematical models in biology Provides step-by-step recipes for constructing and analyzing models Interesting biological applications Explores classical models in ecology and evolution Questions at the end of every chapter Primers cover important mathematical topics Exercises with answers Appendixes summarize useful rules Labs and advanced material available