Measuring Biological Impacts Of Nanomaterials

Author : Joachim Wegener
Publisher : Springer
Page : 214 pages
File Size : 47,5 Mb
Release : 2016-02-02
Category : Science
ISBN : 9783319248233

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Measuring Biological Impacts of Nanomaterials by Joachim Wegener Pdf

This book reviews several aspects of the biological response to nanoscale particles on a molecular and cellular level. Nanoscale materials and nanoscale particles in particular have interesting properties and beneficial applications. While they thus have entered our daily lifes on many different levels (from electronics, over textiles, packaging or surface modifications, to biomedical applications), general rules describing their interaction with biological structures and biological matter are still difficult to derive. The existing literature suggests a variety of interaction schemes between nanoparticles and biological objects, not dispelling the public concerns about possible health effects and harmful properties. A systematic approach to the problem is needed and timely. This book specifically emphasizes bioanalytical problems starting from the characterization of the nanomaterials to the pitfalls and potential artifacts of state-of-the-art cytotoxicity assays that are frequently used to study harmful effects on cells. It also highlights the application of label-free bioanalytical techniques that can potentially complement the present approaches and hence provide new perspectives on this highly discussed cutting-edge field of research and public concern.

Author : Peter Gehr,Reinhard Zellner
Publisher : Springer
Page : 344 pages
File Size : 52,7 Mb
Release : 2019-04-16
Category : Science
ISBN : 9783030124618

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Biological Responses to Nanoscale Particles by Peter Gehr,Reinhard Zellner Pdf

In this book the recent progress accumulated in studies of the interaction of engineered nanoparticles with cells and cellular constituents is presented. The focus is on manufacturing and characterization of nanosized materials, their interactions with biological molecules such as proteins, the mechanisms of transport across biological membranes as well as their effects on biological functions. Fundamental molecular and cellular aspects are in the foreground of the book. A further particularity is the interdisciplinary approach, including fields such as preparatory and analytical chemistry, biophysics and the physics of colloids, advanced microscopy and spectroscopy for in-situ detection of nanoparticles, cellular toxicology and nanomedicine. Nanoscale particles are known to exhibit novel and unprecedented properties that make them different from their corresponding bulk materials. As our ability to control these properties is further advanced, a huge potential to create materials with novel properties and applications emerges. Although the technological and economic benefits of nanomaterials are indisputable, concerns have also been raised that nanoscale structuring of materials might also induce negative health effects. Unfortunately, such negative health effects cannot be deduced from the known toxicity of the corresponding macroscopic material. As a result, there is a major gap in the knowledge necessary for assessing their risk to human health.

Author : Vijaykumar B. Sutariya,Yashwant Pathak
Publisher : CRC Press
Page : 484 pages
File Size : 43,8 Mb
Release : 2014-07-29
Category : Medical
ISBN : 9781466582385

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Biointeractions of Nanomaterials by Vijaykumar B. Sutariya,Yashwant Pathak Pdf

An examination of the widespread application of nano materials in biology, medicine, and pharmaceuticals and the accompanying safety concerns, Bio-interactions of Nano Materials addresses the issues related to toxicity and safety of nano materials and nano systems. It covers the interactions in biological systems and presents various tools and methods used to evaluate the nano toxicity and nano safety issues. Written by leading scientists, the book focuses on the bio-interaction of nano materials, covering various techniques and tests which have been developed to evaluate the toxicity of materials at the nano level. The book highlights the challenges of bio-interactions of nano materials and possible solutions to those challenges. It addresses the assessment and characterization of nano systems in bio-environments, toxicity and bio-sensing devices for toxicity assessment, carbon nano tubes and pulmonary toxicity, and nano toxicity of solid lipid nanoparticles. It also discusses nano safety concerns and solutions, including the effects of nano particles on different organs and regulatory implications of nano materials. These particles may be used to encapsulate drugs, recognize biological markers, or visualize body tissues among many other possibilities, all enabling their widespread application in biology, medicine, and pharmaceutics. Indeed, these nano materials may have beneficial effects that have not even been imagined. This book gives you an understanding of the safety issues, how to assess for them, and how to mitigate them to move forward in research and development of new applications for nano materials.

Author : Namita Agrawal,Prasanna Shah
Publisher : Springer Nature
Page : 128 pages
File Size : 41,9 Mb
Release : 2020-08-24
Category : Medical
ISBN : 9789811555220

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Toxicology of Nanoparticles: Insights from Drosophila by Namita Agrawal,Prasanna Shah Pdf

This book offers an unparalleled source of information on in vivo assessment of nanoparticle toxicity by using Drosophila as a model organism. Nanoparticles have emerged as an useful tool for wide variety of biomedical, cosmetics, and industrial applications. However, our understanding of nanomaterial-mediated toxicity under in vivo condition remains limited. The book begins with a chapter on synthesis and characterization of nanoparticles used for various biological, medical and commercial purposes. The rest of the chapters deal with the impact of nanoparticles on different biological aspects like behavior, physiology and metabolic homoeostasis using Drosophila as a model organism. Lastly, the book summarizes how proper characterization and evaluation of safe dosage of nanoparticles can be a boon if incorporated in consumer goods and for biomedical applications. Overall, the book pursues an interdisciplinary approach by connecting nanotechnology and biology from various angles using Drosophila as a model system, so as to develop more efficient, safe and effective use of nanoparticles for human beings.

Author : Anonim
Publisher : Elsevier
Page : 320 pages
File Size : 52,9 Mb
Release : 2015-06-01
Category : Technology & Engineering
ISBN : 9780080999500

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Characterization of Nanomaterials in Complex Environmental and Biological Media by Anonim Pdf

Characterization of Nanomaterials in Complex Environmental and Biological Media covers the novel properties of nanomaterials and their applications to consumer products and industrial processes. The book fills the growing gap in this challenging area, bringing together disparate strands in chemistry, physics, biology, and other relevant disciplines. It provides an overview on nanotechnology, nanomaterials, nano(eco)toxicology, and nanomaterial characterization, focusing on the characterization of a range of nanomaterial physicochemical properties of relevance to environmental and toxicological studies and their available analytical techniques. Readers will find a multidisciplinary approach that provides highly skilled scientists, engineers, and technicians with the tools they need to understand and interpret complicated sets of data obtained through sophisticated analytical techniques. Addresses the requirements, challenges, and solutions for nanomaterial characterization in environmentally complex media Focuses on technique limitations, appropriate data collection, data interpretation, and analysis Aids in understanding and comparing nanomaterial characterization data reported in the literature using different analytical tools Includes case studies of characterization relevant complex media to enhance understanding

Author : United States. Congress. House. Committee on Science
Publisher : Unknown
Page : 196 pages
File Size : 40,6 Mb
Release : 2006
Category : Political Science
ISBN : PSU:000058937709

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Research on Environmental and Safety Impacts of Nanotechnology by United States. Congress. House. Committee on Science Pdf

Author : Jürgen Gailer,Raymond J. Turner
Publisher : Walter de Gruyter GmbH & Co KG
Page : 424 pages
File Size : 53,8 Mb
Release : 2022-06-21
Category : Science
ISBN : 9783110626346

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Environmental and Biochemical Toxicology by Jürgen Gailer,Raymond J. Turner Pdf

This text coherently links biochemical fundamentals and mechanisms with economic and societal problems of environmental pollution. It addresses interdisciplinary topics such as regulatory problems, sampling and pollutant quantifi cation, model organisms and provides a philosophical perspective on the toxin load on a variety of organisms, including humans in the environment in the Anthropocene. Case studies and exercises illustrate current issues and discuss future aspects.

Author : Mark Wiesner,Jean-Yves Bottero
Publisher : McGraw Hill Professional
Page : 554 pages
File Size : 44,5 Mb
Release : 2007-06-05
Category : Technology & Engineering
ISBN : 9780071511049

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Environmental Nanotechnology by Mark Wiesner,Jean-Yves Bottero Pdf

Explore the Properties of Today's Widely Used Nanomaterials— and Assess Their Potentially Harmful Effects on the Environment Environmental Nanotechnology is the first book to assist you in both understanding the properties of new nanomaterial-centered technology and assessing the potentially harmful effects these materials may have on the environment. Written by a team of 29 leading experts from around the world, this comprehensive book presents cutting-edge coverage of the fabrication, characterization, and measurement of nanomaterials...emerging markets for nanomaterials...nanotechnologies in the energy industry...nanotechnologies for environmental quality...nanotechnology transport and fate in the environment...toxicological impacts of nanomaterials...and much more. Filled with detailed illustrations, Environmental Nanotechnology features: State-of-the-art techniques for the characterization and measurement of nanomaterials The latest findings on the transport and fate of nanomaterials in the environment Nanotechnologies for energy production, storage, and distribution In-depth analyses of the ecotoxicological impacts of nanomaterials New methods for developing nanomaterials with less environmental risk Inside This Landmark Environmental Engineering Guide _ • Nanomaterials: New Challenges and Opportunities • Fabrication of Nanomaterials • Characterization and Measurement of Nanomaterials • Emerging Markets for Nanomaterials • Nanomaterial-Enabled Technologies for Energy Production, Storage, and Distribution • Nanomaterial-Enabled Technologies for Environmental Quality • Nanomaterial Transport and Fate in the Environment • Ecotoxicological Impacts of Nanomaterials • Toxicological Impacts of Nanomaterials

Author : Challa S. S. R. Kumar,Josef Hormes,Carola Leuschner
Publisher : John Wiley & Sons
Page : 442 pages
File Size : 53,9 Mb
Release : 2006-03-06
Category : Technology & Engineering
ISBN : 9783527604609

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Nanofabrication Towards Biomedical Applications by Challa S. S. R. Kumar,Josef Hormes,Carola Leuschner Pdf

This book focuses on the materials, synthetic methods, tools and techniques being developed in the nanoregime towards the life sciences -- in particular biology, biotechnology and medicine. Readers from materials science, engineering, chemistry, biology and medical backgrounds will find detailed accounts of the design and synthesis of nanomaterials and the tools and techniques involved in their production for applications in biology, biotechnology and medicine.

Author : Ineke Malsch,Claude Emond
Publisher : CRC Press
Page : 376 pages
File Size : 55,9 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9780849381454

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Nanotechnology and Human Health by Ineke Malsch,Claude Emond Pdf

Addressing medium- and long-term expectations for human health, this book reviews current scientific and technical developments in nanotechnology for biomedical, agrofood, and environmental applications. This collection of perspectives on the ethical, legal, and societal implications of bionanotechnology provides unique insight into contemporary te

Author : Vijay Pratap Singh,Samiksha Singh,Durgesh Kumar Tripathi,Sheo Mohan Prasad,Devendra Kumar Chauhan
Publisher : Springer Nature
Page : 339 pages
File Size : 41,6 Mb
Release : 2021-04-01
Category : Science
ISBN : 9783030367404

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Plant Responses to Nanomaterials by Vijay Pratap Singh,Samiksha Singh,Durgesh Kumar Tripathi,Sheo Mohan Prasad,Devendra Kumar Chauhan Pdf

The population of the world continues to increase at an alarming rate. The trouble linked with overpopulation ranges from food and water scarcity to inadequacy of space for organisms. Overpopulation is also linked with several other demographic hazards, for instance, population blooming will not only result in exhaustion of natural repositories, but it will also induce intense pressure on the world economy. Today nanotechnology is often discussed as a key discipline of research but it has positive and negative aspects. Also, due to industrialization and ever-increasing population, nano-pollution has been an emerging topic among scientists for investigation and debate. Nanotechnology measures any substance on a macromolecular scale, molecular scale, and even atomic scale. More importantly, nanotechnology deals with the manipulation and control of any matter at the dimension of a single nanometer. Nanotechnology and nanoparticles (NPs) play important roles in sustainable development and environmental challenges as well. NPs possess both harmful and beneficial effects on the environment and its harboring components, such as microbes, plants, and humans. There are many beneficial impacts exerted by nanoparticles, however, including their role in the management of waste water and soil treatment, cosmetics, food packaging, agriculture, biomedicines, pharmaceuticals, renewable energies, and environmental remedies. Conversely, NPs also show some toxic effects on microbes, plants, as well as human beings. It has been reported that use of nanotechnological products leads to the more accumulation of NPs in soil and aquatic ecosystems, which may be detrimental for living organisms. Further, toxic effects of NPs on microbes, invertebrates, and aquatic organisms including algae, has been measured. Scientists have also reported on the negative impact of NPs on plants by discussing the delivery of NPs in plants. Additionally, scientists have also showed that NPs interact with plant cells, which results in alterations in growth, biological function, gene expression, and development. Thus, there has been much investigated and reported on NPs and plant interactions in the last decade. This book discusses the most recent work on NPs and plant interaction, which should be useful for scientists working in nanotechnology across a wide variety of disciplines.

Author : Anonim
Publisher : Unknown
Page : 176 pages
File Size : 48,8 Mb
Release : 2018
Category : Botany
ISBN : UIUC:30112125038007

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Romanian Journal of Biology by Anonim Pdf

Author : Bengt Fadeel,Antonio Pietroiusti,Anna A. Shvedova
Publisher : Academic Press
Page : 367 pages
File Size : 44,7 Mb
Release : 2012-01-27
Category : Medical
ISBN : 9780123869401

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Adverse Effects of Engineered Nanomaterials by Bengt Fadeel,Antonio Pietroiusti,Anna A. Shvedova Pdf

An essential reference that discusses occupational exposure and the adverse health effects of engineered nanomaterials and highlights current and future biomedical applications of these nanomaterials in relation to nanosafety.

Author : Masoud Mozafari,Narendra Pal Singh Chauhan
Publisher : Woodhead Publishing
Page : 802 pages
File Size : 51,8 Mb
Release : 2023-08-25
Category : Technology & Engineering
ISBN : 9780128237984

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Handbook of Polymers in Medicine by Masoud Mozafari,Narendra Pal Singh Chauhan Pdf

Handbook of Polymers in Medicine combines core concepts and advanced research on polymers, providing a better understanding of this class of materials in medicine. The book covers all aspects of medical polymers from characteristics and biocompatibility, to the diverse array of applications in medicine. Chapters cover an introduction to polymers in medicine and the challenges associated with biocompatibility in human tissue, polyurethane and supramolecular polymers and their specific applications in medicine, from tissue regeneration to orthopedic surgery and cancer therapeutics. This book offers an interdisciplinary approach that will appeal to researchers in a range of disciplines, including biomedical engineering, materials science, chemistry, pharmacology and translational medicine. The book will also make a useful reference for clinicians and those in medical fields who are interested in materials for medical applications, as well as R&D groups involved in medical device design. Systematically covers individual polymer classes, from characteristics and biocompatibility to applications in biomedicine Covers a broad range of applications in medicine, such as cardiac tissue engineering, targeted drug delivery, dentistry, and more Provides an interdisciplinary review of polymers in medicine, allowing advanced students and experienced researchers in a range of biomedical and clinical fields to learn more about this fast-evolving area

Author : Nancy A. Monteiro-Riviere,C. Lang Tran
Publisher : CRC Press
Page : 516 pages
File Size : 48,7 Mb
Release : 2014-03-03
Category : Medical
ISBN : 9781482203875

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Nanotoxicology by Nancy A. Monteiro-Riviere,C. Lang Tran Pdf

Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.