Mechanisms And Therapy Of Liver Cancer

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Mechanisms and Therapy of Liver Cancer

Anonim
Mechanisms and Therapy of Liver Cancer Book PDF

Author : Anonim
Publisher : Academic Press
Page : 404 pages
File Size : 43,5 Mb
Release : 2021-02-10
Category : Medical
ISBN : 9780128240311

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Mechanisms and Therapy of Liver Cancer by Anonim Pdf

Mechanisms and Therapy of Liver Cancer, Volume 149, presents the latest information on the incidence and mortality of liver cancer research and how it has gained significant momentum because of its direct causative association with obesity-induced fatty liver disease. The literature on liver cancer is moving fast with exciting, novel findings, providing new insights reflected in the following updated chapters: Introduction and molecular classification of HCC, Signaling Pathways in Liver Cancer, HCV and HCC, NASH and HCC, Microbiome and Metabolic Abnormalities in HCC, Systemic Therapy of Liver Cancer, Immunotherapy of Liver Cancer, and Desmoplastic Tumor Microenvironment and Intrahepatic Cholangiocarcinoma Progression: Mechanisms and Therapeutic Implications. Provides the latest information on liver cancer research Offers outstanding and original reviews on a range of topics focused on liver cancer Serves as an indispensable reference on liver cancer for researchers and students alike

Liver Cancers

Tim Cross,Daniel H. Palmer
Liver Cancers Book PDF

Author : Tim Cross,Daniel H. Palmer
Publisher : Springer
Page : 312 pages
File Size : 42,8 Mb
Release : 2018-12-12
Category : Medical
ISBN : 9783319922164

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Liver Cancers by Tim Cross,Daniel H. Palmer Pdf

This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy. Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these. Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding. This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery

Hepatocellular Carcinoma

Rajagopal N. Aravalli,Clifford J. Steer
Hepatocellular Carcinoma Book PDF

Author : Rajagopal N. Aravalli,Clifford J. Steer
Publisher : Springer
Page : 69 pages
File Size : 52,8 Mb
Release : 2014-09-15
Category : Medical
ISBN : 9783319094144

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Hepatocellular Carcinoma by Rajagopal N. Aravalli,Clifford J. Steer Pdf

This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process. Recent research in HCC has led to significant progress in our understanding of the cellular processes and molecular mechanisms that occur during multi-stage events that lead to hepatocarcinogenesis. The emergence of micro RNAs and molecular targeted therapies have added a new dimension in our efforts to combat this deadly disease, Chapters include discussion and evaluation of current intervention strategies and therapeutic options and a focus on the novel approaches that are being pursued, such as micro-RNA based therapies and personalized medicine to treat liver cancer. This book will be of interest to basic and clinical researchers, as well as to drug developers.

Immunotherapy of Hepatocellular Carcinoma

Tim F. Greten
Immunotherapy of Hepatocellular Carcinoma Book PDF

Author : Tim F. Greten
Publisher : Springer
Page : 167 pages
File Size : 50,8 Mb
Release : 2017-10-04
Category : Medical
ISBN : 9783319649580

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Immunotherapy of Hepatocellular Carcinoma by Tim F. Greten Pdf

In this book we provide insights into liver – cancer and immunology. Experts in the field provide an overview over fundamental immunological questions in liver cancer and tumorimmunology, which form the base for immune based approaches in HCC, which gain increasing interest in the community due to first promising results obtained in early clinical trials. Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death in the United States. Treatment options are limited. Viral hepatitis is one of the major risk factors for HCC, which represents a typical “inflammation-induced” cancer. Immune-based treatment approaches have revolutionized oncology in recent years. Various treatment strategies have received FDA approval including dendritic cell vaccination, for prostate cancer as well as immune checkpoint inhibition targeting the CTLA4 or the PD1/PDL1 axis in melanoma, lung, and kidney cancer. Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma. Immune checkpoint inhibitors in particular have generated enormous excitement across the entire field of oncology, providing a significant benefit to a minority of patients.

Hepatocellular Carcinoma

Brian I. Carr
Hepatocellular Carcinoma Book PDF

Author : Brian I. Carr
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 53,7 Mb
Release : 2009-10-03
Category : Medical
ISBN : 9781603273763

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Hepatocellular Carcinoma by Brian I. Carr Pdf

Hepatocellular cancer is the fifth most common cancer, with 600,000 new cases reported each year worldwide. Additionally, exciting changes in the science of HCC in the last four years have turned the practice of diagnosing and treating the disease upside down. In Hepatocellular Carcinoma: Diagnosis and Treatment, Second Edition, the leading experts in the field of HCC thoroughly update and expand upon the critically acclaimed first edition with all the latest developments in the diagnosis and treatment of primary liver cancer. The book details for physicians the diagnostic and therapeutic decision making process for dealing with such problems as incidental tumors in the liver transplant, the role of neo-adjuvant chemotherapy, intra-arterial vs intravenous therapy, the uses of embolization, and the significance of portal vein thrombus. New chapters discuss the introduction into clinical practice of cell cycle growth inhibitors, an expanded knowledge of Genomics and Proteomics, and novel ways of delivering intra-hepatic chemotherapy. This cutting-edge text is a vital resource and must have for today’s hepatologists and medical and surgical oncologists.

Advances in Cancer Research

Anonim
Advances in Cancer Research Book PDF

Author : Anonim
Publisher : Elsevier
Page : 332 pages
File Size : 47,9 Mb
Release : 2023-09-12
Category : Medical
ISBN : 9780443192814

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Advances in Cancer Research by Anonim Pdf

Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Liver Regeneration and Carcinogenesis

Gerard Meurant
Liver Regeneration and Carcinogenesis Book PDF

Author : Gerard Meurant
Publisher : Elsevier
Page : 402 pages
File Size : 40,7 Mb
Release : 1995-09-27
Category : Science
ISBN : 0080535542

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Liver Regeneration and Carcinogenesis by Gerard Meurant Pdf

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Dx/Rx: Liver Cancer

Ghassan K. Abou-Alfa,Celina Ang
Dx Rx Liver Cancer Book PDF

Author : Ghassan K. Abou-Alfa,Celina Ang
Publisher : Jones & Bartlett Publishers
Page : 167 pages
File Size : 42,8 Mb
Release : 2012-12-23
Category : Medical
ISBN : 9781449646868

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Dx/Rx: Liver Cancer by Ghassan K. Abou-Alfa,Celina Ang Pdf

Dx/Rx: Liver Cancer is a quick and practical reference guide containing all aspects of the diagnosis and therapy of hepatocellular carcinoma (HCC), prognostic and staging systems, clinical management, molecular biology, current controversies, and future insights. Organized into a condensed, bulleted format, this concise reference offers precise and up-to-date information on the epidemiology, classification, diagnosis, treatment, and risk factors for cancers of the liver. Presented in a handy, easy-to-read format, Dx/Rx: Liver Cancer is a must-have resource for oncologists, internists, primary care physicians, and other health care professionals on the ward or in the clinic.

Hepatocellular Carcinoma

Costin Teodor Streba,Cristin Constantin Vere,Ion Rogoveanu
Hepatocellular Carcinoma Book PDF

Author : Costin Teodor Streba,Cristin Constantin Vere,Ion Rogoveanu
Publisher : BoD – Books on Demand
Page : 201 pages
File Size : 52,6 Mb
Release : 2018-11-28
Category : Medical
ISBN : 9781789842739

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Hepatocellular Carcinoma by Costin Teodor Streba,Cristin Constantin Vere,Ion Rogoveanu Pdf

Hepatocellular carcinoma (HCC) currently ranks as the third most common cause of death. As the primary malignancy of the liver is directly related to an underlying liver condition, its incidence and profile are expected to change soon. While effective prevention programs and antiviral therapies for hepatitis B and C will lower the incidence of HCC, emerging socioeconomic issues will deliver new at-risk populations. Moreover, diagnostic techniques and protocols have undergone significant advancements. Reliance on contrast enhanced ultrasound has been re-evaluated, imaging methods being considered as sufficient diagnostic tools. Molecular characterization remains desirable, since chemotherapeutic agents still have limited applicability. In light of recent diagnostic advancements and novel therapeutic solutions, it is our belief that a comprehensive update on recent paradigm shifts and interesting upcoming developments is highly needed.

Liver Cancer

Benjamin J. Valverde
Liver Cancer Book PDF

Author : Benjamin J. Valverde
Publisher : Nova Biomedical Books
Page : 0 pages
File Size : 40,7 Mb
Release : 2011
Category : Liver
ISBN : 1612091156

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Liver Cancer by Benjamin J. Valverde Pdf

Primary liver cancer, mainly hepatocellular carcinoma (HCC), is the third leading cause of cancer-related deaths world-wide. The incidence is increasing world-wide and the overall survival of patients with HCC is grim because most patients are diagnosed late, when curative treatment is not possible. This book presents topical research in the study of liver cancer, including plant polyphenols for the prevention of HCC and therapy of liver cancer; cytotoxic effects of reservatrol against liver cancer; the molecular mechanisms of HCC and the identification of prognostic markers and health-related quality of life for patients with liver cancer.

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2

Ganji Purnachandra Nagaraju,Ramakrishna Vadde
Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma Volume 2 Book PDF

Author : Ganji Purnachandra Nagaraju,Ramakrishna Vadde
Publisher : Academic Press
Page : 399 pages
File Size : 44,5 Mb
Release : 2022-04-02
Category : Psychology
ISBN : 9780323993654

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Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2 by Ganji Purnachandra Nagaraju,Ramakrishna Vadde Pdf

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume Two: Diagnosis, Therapeutic Targets and Molecular Mechanisms for Hepatocellular Carcinoma Progression provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. The volume discusses topics such as computational approaches for identification of biomarkers, enzymes and pathways of HCC, circulating and epigenetic biomarkers, drug resistance, metabolic pathways, and small molecule-target therapies. In addition, it discusses immunotherapies, immune check point inhibitors and nanotechnology-based therapies. This book is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting. Provides detailed information on traditional and novel diagnostic tools for hepatocellular carcinoma Discusses promising targeted therapies, both available and in development, explaining the best option to use for specific cases Brings recent findings in immunotherapies, immune checkpoint inhibitors and nanotechnology-based therapeutic approaches for treatment of HCC

Liver Cancer in the Middle East

Brian I. Carr
Liver Cancer in the Middle East Book PDF

Author : Brian I. Carr
Publisher : Springer Nature
Page : 408 pages
File Size : 55,7 Mb
Release : 2021-09-22
Category : Medical
ISBN : 9783030787370

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Liver Cancer in the Middle East by Brian I. Carr Pdf

This book aims to illuminate the causes, incidence, and treatments of Hepatocellular Carcinoma(HCC) or liver cancer in the politically important and societally diverse region of the Middle East. Taking a flexible and inclusive view, it examines the influences of geography, crops and diet, ethnicity, and local behavior on both diagnosis and outcomes of this disease. Understanding the different causes of liver cancer enables effective strategies for both prevention and early diagnosis while knowledge of the different treatment modalities, their uses and limitations, availability and costs, works to inform rational treatment provision and selection. Divided into four sections, this book considers the causes and clinical syndromes associated with HCC, provides a detailed overview of clinical HCC and treatment modalities, describes country-specific clinical HCC experience and practice, and considers future needs and the potential for HCC collaborations across the region. Liver Cancer in the Middle East is a useful resource for clinicians seeking insight into the second highest cause of death from cancer worldwide, governments planning social and medical services for their peoples, as well as for international aid agencies prioritizing donations.

Malignant Liver Tumors

Pierre-Alain Clavien,Stefan Breitenstein,Jacques Belghiti,Ravi S. Chari,Josep M. Llovet,Chung-Mau Lo,Michael A. Morse,Tadatoshi Takayama,Jean-Nicolas Vauthey
Malignant Liver Tumors Book PDF

Author : Pierre-Alain Clavien,Stefan Breitenstein,Jacques Belghiti,Ravi S. Chari,Josep M. Llovet,Chung-Mau Lo,Michael A. Morse,Tadatoshi Takayama,Jean-Nicolas Vauthey
Publisher : John Wiley & Sons
Page : 1039 pages
File Size : 45,6 Mb
Release : 2011-09-23
Category : Medical
ISBN : 9781444356397

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Malignant Liver Tumors by Pierre-Alain Clavien,Stefan Breitenstein,Jacques Belghiti,Ravi S. Chari,Josep M. Llovet,Chung-Mau Lo,Michael A. Morse,Tadatoshi Takayama,Jean-Nicolas Vauthey Pdf

This comprehensive and critical review of current and established treatment modalities for malignant liver tumors is designed to help you sort through the proliferation of competitive approaches and choose the best treatment options for your patient. Dr. Clavien and his contributors consider all the options – radiological, surgical, pharmaceutical, and emerging/novel therapies – and help you find the best single or combined therapy. Building on the success of the previous edition, this extremely thorough revision: features a new section on Guidelines for Liver Tumors, where you will find specific strategies for treating common liver malignancies; the guidelines were prepared by the Associate Editors and take into account national and international society guidelines reflects actual practice by taking a multidisciplinary approach, with contributions from international experts who have extensive experience with this patient population achieves comprehensive and balanced coverage by having each chapter reviewed by the Editor, Deputy Editor, two Associate Editors, and at least one external reviewer includes 16 new chapters that cover liver anatomy, histologic changes in the liver, epidemiology and natural history of HCC, CCC and colorectal liver metastases, strategies of liver resection, and economic aspects as well as novel therapies facilitates the kind of daily interaction among hepatologists, hepatic surgeons, medical oncologists, radiotherapists, and interventional radiologists that is essential when treating patients with complex liver malignancies In 44 chapters organized into six major sections, the book covers the full range of liver tumors. The perfect blend of evidence and experience, Malignant Liver Tumors: Current and Emerging Therapies, 3rd Edition, illuminates the path to better patient care.

Holland-Frei Cancer Medicine

Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Holland Frei Cancer Medicine Book PDF

Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Page : 2008 pages
File Size : 55,7 Mb
Release : 2017-03-10
Category : Medical
ISBN : 9781119000846

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Holland-Frei Cancer Medicine by Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland Pdf

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Drug-Induced Liver Injury

Anonim
Drug Induced Liver Injury Book PDF

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 54,9 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series