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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Regulation of Gene Expression in Animal Viruses by Luis Carrasco,Nahum Sonenberg,Eckard Wimmer Pdf
Viruses, being obligatory parasites of their host cells, rely on a vast supply of cellular components for their replication, regardless of whether infection leads to cell death or to the state of persistence. Animal viruses are providing scientists with relatively simple models to study the molecular biology of genome replication and gene expression. Whereas viruses use, in general, pathways of macromolecular biosynthesis common to the host cell, they have a cunning ability to adopt unusual mechanisms of gene expression and gene replication, provided these special pathways offer an advantage in competition for cellular resources. Any study of viral gene expression and replication is likely to lead also to new insights in cellular metabolism. The discoveries of cis-acting regulatory elements in transcription, the phenomenon of splicing of pre mRNA, and cap-dependent and cap-independent initiation of translation may be cited as examples. In addition, animal virus genomes contain elements and encode proteins that are very useful for the design of vectors for gene cloning and expression in mammalian cells. Apart from the basic interest in their biology, viruses have gained notoriety, of course, because they are pathogens. Human animal viruses may cause diseases ranging from the deadly (AIDS) to the benign (common cold). All studies on animal viruses potentially lead to the development of tools for their control, be it through prevention by immunization or treatment with antiviral drugs. Finally, viruses have yielded invaluable reagents in molecular biology as, for example, the vaccinia virus vector for the expression of foreign genes.
Frederick A. Murphy,E. Paul J. Gibbs,Marian C. Horzinek,Michael J. Studdert
Author : Frederick A. Murphy,E. Paul J. Gibbs,Marian C. Horzinek,Michael J. Studdert Publisher : Elsevier Page : 629 pages File Size : 42,5 Mb Release : 1999-10-27 Category : Medical ISBN : 008055203X
Veterinary Virology by Frederick A. Murphy,E. Paul J. Gibbs,Marian C. Horzinek,Michael J. Studdert Pdf
Completely rewritten, this edition has expanded coverage of zoonotic viruses and the diseases they cause, and viruses and viral diseases of laboratory animals, poultry, fish, and wildlife. The concept of new emerging and reemerging viral diseases reflects the new perspective this concept has brought to veterinary and zoonotic virology and related fields. Part I presents fundamental principles of virology related to animal infection and disease. Part II details the properties and clinical features of the viruses that afflict animals and describes their treatment and control. Key Features * Comprehensive coverage of animal viruses, viral diseases, and viral zoonoses * Covers veterinary and zoonotic virology from the perspective of pathogenesis of viral infections, as well as from the perspective of disease prevention and control
Cell Culture Engineering IV, Improvements of Human Health covers the latest approaches to improving the cell host through improved understanding of the molecular biology, the development of novel vaccines, approaches to bioreactor design and operation, monitoring techniques in process control and quality related topics. The work was carefully put together as one result of the Cell Culture Engineering IV Meeting held in San Diego, U.S.A. in 1994, however, the book may not be perceived as a proceedings volume - the criteria of the book series apply. For cell biologists, biochemists, molecular biologists, immunologists and other disciplines related to cell culture engineering, working in the academic environment, as well as in (biotechnology or pharmaceutical) industry.
National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Publisher : National Academies Press Page : 348 pages File Size : 54,9 Mb Release : 2000-12-21 Category : Nature ISBN : 9780309070867
Scientific Frontiers in Developmental Toxicology and Risk Assessment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Pdf
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines
Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines Publisher : National Academies Press Page : 894 pages File Size : 52,6 Mb Release : 2012-04-26 Category : Medical ISBN : 9780309214353
Adverse Effects of Vaccines by Institute of Medicine,Board on Population Health and Public Health Practice,Committee to Review Adverse Effects of Vaccines Pdf
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
Howard E. Gendelman, MD,Igor Grant, MD,Ian Paul Everall, MD, PhD,Howard S. Fox, MD, PhD,Harris A. Gelbard, MD, PhD,Stuart A. Lipton, MD, PhD,Susan Swindells, MBBS
Author : Howard E. Gendelman, MD,Igor Grant, MD,Ian Paul Everall, MD, PhD,Howard S. Fox, MD, PhD,Harris A. Gelbard, MD, PhD,Stuart A. Lipton, MD, PhD,Susan Swindells, MBBS Publisher : Oxford University Press Page : 1156 pages File Size : 52,8 Mb Release : 2011-11-29 Category : Medical ISBN : 9780199875559
The Neurology of AIDS by Howard E. Gendelman, MD,Igor Grant, MD,Ian Paul Everall, MD, PhD,Howard S. Fox, MD, PhD,Harris A. Gelbard, MD, PhD,Stuart A. Lipton, MD, PhD,Susan Swindells, MBBS Pdf
From basic science to clinical care, to epidemiological disease patters, The Neurology of AIDS is the only complete textbook available on AIDS neurology and the only one comprehensive enough to stand alone in each segment of study in brain disorders affected by the human immunodeficiency virus. It is an indispensable resource for students, resident physicians, practicing physicians, and for researchers and experts in the HIV/AIDS field. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Author : David O. White,Frank J. Fenner Publisher : Gulf Professional Publishing Page : 626 pages File Size : 46,5 Mb Release : 1994-06-27 Category : Medical ISBN : 0127466428
Medical Virology by David O. White,Frank J. Fenner Pdf
Medical Virology first appeared in 1970 and was immediately hailed as a classic. The Fourth Edition has been completely updated, substantially rewritten, and considerably expanded. Acknowledging that today's students possess a more sophisticated background of molecular and cellular biology, the book is pitched a little higher than was the third edition. Nevertheless, it maintains the exceptionally high standards of the three previous editions, including the now famous user-friendly style. Hundreds of instructive diagrams and succinct tables smooth the path for the reader. Extensive lists of recent authoritative reviews at the end of each of the 36 chapters simplifies the reader's entry into the scientific literature. Throughout, the focus is on fundamental principles, mechanisms and basic facts, rather than on overwhelming detail. Part I of the book, expanded to over 400 pages, comprises in effect a self-contained overview of the Principles of Virology. Part II, entitled Viruses of Humans, deals comprehensively with all the families of human viruses. Extensive coverage is given to the molecular biology of the viruses and of viral replication, pathogenesis and immunity, clinical features of all important diseases caused by all viruses affecting humans, the latest laboratory diagnostic methods, epidemiology and control, including chemotherapy and vaccines. This lucid and concise yet comprehensive text is admirably suited to the needs not only of advanced students of science and medicine but also particularly of postgraduate students, teachers, and research workers in all areas of virology. Molecular biology of viruses and viral replication Pathogenesis and immunity Latest laboratory diagnostic methods Clinical features of human viral diseases Vaccines and chemotherapy Epidemiology and control
National Institutes of Health (U.S.). Division of Research Grants
Author : National Institutes of Health (U.S.). Division of Research Grants Publisher : Unknown Page : 1224 pages File Size : 44,6 Mb Release : 1975 Category : Medicine ISBN : UOM:39015072175246