Metal Catalyzed Reactions In Water

Author : Pierre Dixneuf,Victorio Cadierno
Publisher : John Wiley & Sons
Page : 438 pages
File Size : 44,9 Mb
Release : 2013-01-17
Category : Technology & Engineering
ISBN : 9783527656813

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Metal-Catalyzed Reactions in Water by Pierre Dixneuf,Victorio Cadierno Pdf

Water is abundant in nature, non-toxic, non-flammable and renewable and could therefore be safer and economical for the chemical industry wherever it is used as a solvent. This book provides a comprehensive overview of developments in the use of water as a solvent for metal catalysis, illustrating the enormous potential of water in developing new catalytic transformations for fi ne chemicals and molecular materials synthesis. A group of international experts cover the most important metalcatalyzed reactions in water and bring together cutting-edge results from recent literature with the first-hand knowledge gained by the chapter authors. This is a must-have book for scientists in academia and industry involved in the fi eld of catalysis, greener organic synthetic methods, water soluble ligands and catalyst design, as well as for teachers and students interested in innovative and sustainable chemistry.

Author : Robertus J. M. Klein Gebbink,Marc-Etienne Moret
Publisher : John Wiley & Sons
Page : 610 pages
File Size : 40,6 Mb
Release : 2019-04-29
Category : Technology & Engineering
ISBN : 9783527340613

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Non-Noble Metal Catalysis by Robertus J. M. Klein Gebbink,Marc-Etienne Moret Pdf

An expert overview of current research, applications, and economic and environmental advantages The study and development of new homogeneous catalysts based on first-row metals (Mn, Fe, Co, Ni, and Cu) has grown significantly due to the economic and environmental advantages that non-noble metals present. Base metals offer reduced cost, greater supply, and lower toxicity levels than noble metals?enabling greater opportunity for scientific investigation and increased development of practical applications. Non-Noble Metal Catalysis provides an authoritative survey of the field, from fundamental concepts and computational methods to industrial applications and reaction classes. Recognized experts in organometallic chemistry and homogeneous catalysis, the authors present a comprehensive overview of the conceptual and practical aspects of non-noble metal catalysts. Examination of topics including non-innocent ligands, proton-coupled electron transfer, and multi-nuclear complexes provide essential background information, while areas such as kinetic lability and lifetimes of intermediates reflect current research and shifting trends in the field. This timely book demonstrates the efficacy of base metal catalysts in the pharmaceutical, fine-chemical, and agrochemical industries, addressing both environmental and economic concerns. Providing essential conceptual and practical exploration, this valuable resource: -Illustrates how unravelling new reactivity patterns can lead to new catalysts and new applications -Highlights the multiple advantages of using non-noble metals in homogenous catalysis -Demonstrates how the availability of non-noble metal catalysis reduces costs and leads to immense savings for the chemical industry -Reveals how non-noble metal catalysis are more sustainable than noble metals such as palladium or platinum Non-Noble Metal Catalysis: Molecular Approaches and Reactions is an indispensable source of up-to-date information for catalytic chemists, organic chemists, industrial chemists, organometallic chemists, and those seeking to broaden their knowledge of catalytic chemistry.

Author : Tamás Patonay,Krisztina Kónya
Publisher : Springer
Page : 362 pages
File Size : 46,8 Mb
Release : 2016-06-15
Category : Science
ISBN : 9783319326108

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Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions by Tamás Patonay,Krisztina Kónya Pdf

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Author : Vivek Polshettiwar,Rajender S. Varma
Publisher : Royal Society of Chemistry
Page : 243 pages
File Size : 52,5 Mb
Release : 2010
Category : Science
ISBN : 9781849730389

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Aqueous Microwave Assisted Chemistry by Vivek Polshettiwar,Rajender S. Varma Pdf

The demands for green and sustainable synthetic methods in the fields of healthcare and fine chemicals, combined with the pressure to produce these substances expeditiously and in an environmentally benign fashion, pose significant challenges to the synthetic chemical community. Green chemistry can avoid pollution by utilizing techniques that are environmentally friendly by design and one of the best green techniques is the use of microwave (MW) assisted aqueous synthetic protocols. Fusing MW technique with water (as a benign reaction medium) can offer an extraordinary synergistic effect with greater potential than these two individual components in isolation. Selective microwave heating can be exploited to develop a high yield protocol and the use of water expedites the MW-protocol with more energy efficiency. This book provides an overview of the various processes developed using aqueous microwave chemistry and is written for chemists, chemical engineers and researchers in the early stages who want to develop sustainable and green processes. Written by well known microwave experts, the book is a comprehensive examination of the field and is the first book that deals strictly with aqueous microwave chemistry and represents a significant effort towards green chemistry. It covers all the microwave-assisted aqueous reactions in depth, including heterocycle synthesis, metal catalysis, enzyme catalysis, polymer synthesis, nanomaterials synthesis and nano-catalysis. Each chapter contains representative experimental procedures, helping the reader quickly replicate some of the experiments to gain hands-on experience.

Author : Javier Magano,Joshua R. Dunetz
Publisher : John Wiley & Sons
Page : 1 pages
File Size : 52,5 Mb
Release : 2013-07-03
Category : Science
ISBN : 9783527658923

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Transition Metal-Catalyzed Couplings in Process Chemistry by Javier Magano,Joshua R. Dunetz Pdf

Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in this book through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients. Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water. With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson's Process Solutions LLC.

Author : Robertus J. M. Klein Gebbink,Marc-Etienne Moret
Publisher : John Wiley & Sons
Page : 450 pages
File Size : 50,7 Mb
Release : 2018-12-19
Category : Technology & Engineering
ISBN : 9783527699117

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Non-Noble Metal Catalysis by Robertus J. M. Klein Gebbink,Marc-Etienne Moret Pdf

An expert overview of current research, applications, and economic and environmental advantages The study and development of new homogeneous catalysts based on first-row metals (Mn, Fe, Co, Ni, and Cu) has grown significantly due to the economic and environmental advantages that non-noble metals present. Base metals offer reduced cost, greater supply, and lower toxicity levels than noble metals?enabling greater opportunity for scientific investigation and increased development of practical applications. Non-Noble Metal Catalysis provides an authoritative survey of the field, from fundamental concepts and computational methods to industrial applications and reaction classes. Recognized experts in organometallic chemistry and homogeneous catalysis, the authors present a comprehensive overview of the conceptual and practical aspects of non-noble metal catalysts. Examination of topics including non-innocent ligands, proton-coupled electron transfer, and multi-nuclear complexes provide essential background information, while areas such as kinetic lability and lifetimes of intermediates reflect current research and shifting trends in the field. This timely book demonstrates the efficacy of base metal catalysts in the pharmaceutical, fine-chemical, and agrochemical industries, addressing both environmental and economic concerns. Providing essential conceptual and practical exploration, this valuable resource: -Illustrates how unravelling new reactivity patterns can lead to new catalysts and new applications -Highlights the multiple advantages of using non-noble metals in homogenous catalysis -Demonstrates how the availability of non-noble metal catalysis reduces costs and leads to immense savings for the chemical industry -Reveals how non-noble metal catalysis are more sustainable than noble metals such as palladium or platinum Non-Noble Metal Catalysis: Molecular Approaches and Reactions is an indispensable source of up-to-date information for catalytic chemists, organic chemists, industrial chemists, organometallic chemists, and those seeking to broaden their knowledge of catalytic chemistry.

Author : P.A. Grieco
Publisher : Springer Science & Business Media
Page : 336 pages
File Size : 50,9 Mb
Release : 1997-12-31
Category : Science
ISBN : 0751404101

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Organic Synthesis in Water by P.A. Grieco Pdf

The use of water as a medium for promoting organic reactions has been rather neglected in the development of organic synthesis, despite the fact that it is the solvent in which almost all biochemical processes take place. Chemists have only recently started to appreciate the enormous potential water has to offer in the development of new synthetic reactions and strategies, where it can offer benefits, in both unique chemistry and reduced environmental impact.

Author : Wei Zhang,Berkeley W. Cue
Publisher : John Wiley & Sons
Page : 769 pages
File Size : 51,7 Mb
Release : 2012-07-23
Category : Medical
ISBN : 9780470711514

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Green Techniques for Organic Synthesis and Medicinal Chemistry by Wei Zhang,Berkeley W. Cue Pdf

Green chemistry is a new way of looking at organic synthesis and the design of drug molecules, offering important environmental and economic advantages over traditional synthetic processes. Pharmaceutical companies are increasingly turning to the principles of green chemistry in an effort to reduce waste, reduce costs and develop environmentally benign processes. Green Techniques for Organic Synthesis and Medicinal Chemistry presents an overview of the established and emerging techniques in green organic chemistry, highlighting their applications in medicinal chemistry. The book is divided into four parts: Introduction: Introduces the reader to the toxicology of organic chemicals,their environmental impact, and the concept of green chemistry. Green Catalysis: Covers a variety of green catalytic techniques including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Green Synthetic Techniques: Presents a series of new techniques, assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise). Techniques include reactions in alternative solvents, atom economic multicomponent reactions, microwave and ultrasonic reactions, solid-supported synthesis, fluorous and ionic liquid-based recycling techniques, and flow reactors. Green Techniques in Pharmaceutical Industry: Covers applications of green chemistry concepts and special techniques for medicinal chemistry, including synthesis, analysis, separation, formulation, , and drug delivery. Process and business case studies are included to illustrate the applications in the pharmaceutical industry. Green Techniques for Organic Synthesis and Medicinal Chemistry is an essential resource on green chemistry technologies for academic researchers, R&D professionals and students working in organic chemistry and medicinal chemistry.

Author : Gian Paolo Chiusoli,Peter M. Maitlis
Publisher : Royal Society of Chemistry
Page : 312 pages
File Size : 45,6 Mb
Release : 2008
Category : Education
ISBN : 9780854041503

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Metal-catalysis in Industrial Organic Processes by Gian Paolo Chiusoli,Peter M. Maitlis Pdf

A definitive reference source, written by practising experts in the field, providing detailed and up-to-date information on key aspects of metal catalysis.

Author : CCPS (Center for Chemical Process Safety)
Publisher : John Wiley & Sons
Page : 526 pages
File Size : 45,6 Mb
Release : 2019-11-05
Category : Technology & Engineering
ISBN : 9781119529163

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Guidelines for Inherently Safer Chemical Processes by CCPS (Center for Chemical Process Safety) Pdf

Since the publication of the second edition several United States jurisdictions have mandated consideration of inherently safer design for certain facilities. Notable examples are the inherently safer technology (IST) review requirement in the New Jersey Toxic Chemical Prevention Act (TCPA), and the Inherently Safer Systems Analysis (ISSA) required by the Contra Costa County (California) Industrial Safety Ordinance. More recently, similar requirements have been proposed at the U.S. Federal level in the pending EPA Risk Management Plan (RMP) revisions. Since the concept of inherently safer design applies globally, with its origins in the United Kingdom, the book will apply globally. The new edition builds on the same philosophy as the first two editions, but further clarifies the concept with recent research, practitioner observations, added examples and industry methods, and discussions of security and regulatory issues. Inherently Safer Chemical Processes presents a holistic approach to making the development, manufacture, and use of chemicals safer. The main goal of this book is to help guide the future state of chemical process evolution by illustrating and emphasizing the merits of integrating inherently safer design process-related research, development, and design into a comprehensive process that balances safety, capital, and environmental concerns throughout the life cycle of the process. It discusses strategies of how to: substitute more benign chemicals at the development stage, minimize risk in the transportation of chemicals, use safer processing methods at the manufacturing stage, and decommission a manufacturing plant so that what is left behind does not endanger the public or environment.

Author : U. Marcus Lindstrom
Publisher : John Wiley & Sons
Page : 424 pages
File Size : 53,7 Mb
Release : 2008-04-15
Category : Science
ISBN : 9780470994245

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Organic Reactions in Water by U. Marcus Lindstrom Pdf

Volatile organic solvents are the normal media used in both research scale and industrial scale synthesis of organic chemicals. Their environmental impact is significant, however, and so the development of alternative reaction media has become of great interest. Developments in the use of water as a solvent for organic synthesis have reached the point where it could now be considered a viable solvent for many organic reactions. Organic Reactions in Water demonstrates the underlying principles of using water as a reaction solvent and, by reference to a range of reaction types and systems, it’s effective use in synthetic organic chemistry. Written by an internationally respected team of contributors, and with a strong focus on the practical use of water as a reaction medium, this book illustrates the enormous potential of water for the development of new and unique chemistries and synthetic strategies, while at the same time offering a much reduced environmental impact.

Author : John P. Wolfe
Publisher : Springer
Page : 276 pages
File Size : 50,6 Mb
Release : 2013-09-11
Category : Science
ISBN : 9783642388804

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Synthesis of Heterocycles via Metal-Catalyzed Reactions that Generate One or More Carbon-Heteroatom Bonds by John P. Wolfe Pdf

Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Carboamination or Carboalkoxylation Reactions, by John P. Wolfe Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Diamination, Aminoalkoxylation, or Dialkoxylation Reactions, by Sherry R. Chemler Synthesis of Heterocycles via Metal-Catalyzed Wacker-Type Oxidative Cyclization Reactions of Alkoxy- or Amino-Alkenes, by Wanbin Zhang Synthesis of Saturated Heterocycles via Metal-Catalyzed Hydroamination or Hydroalkoxylation Reactions, by Lisa D. Julian Synthesis of Saturated Heterocycles via Metal-Catalyzed Allylic Alkylation Reactions, by Aaron Aponick Synthesis of Heterocycles via Metal-Catalyzed Cascade/Domino Reactions that Generate a C–N or C–O Bond, by Mark Lautens Synthesis of Saturated Heterocycles via Metal-Catalyzed Formal Cycloaddition Reactions that Generate a C–N or C–O Bond, by Jerome Waser

Author : István T. Horváth,Ferenc Joó
Publisher : Springer Science & Business Media
Page : 317 pages
File Size : 51,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401103558

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Aqueous Organometallic Chemistry and Catalysis by István T. Horváth,Ferenc Joó Pdf

Proceedings of the NATO Advanced Research Workshop, Debrecen, Hungary, August 29--September 1, 1994

Author : International Union of Pure and Applied Chemistry
Publisher : Unknown
Page : 524 pages
File Size : 52,5 Mb
Release : 1999
Category : Science
ISBN : UOM:39015050032583

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Transition Metal Catalysed Reactions by International Union of Pure and Applied Chemistry Pdf

Author : P.-O. Löwdin,A. Pullman
Publisher : Springer Science & Business Media
Page : 448 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400979505

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New Horizons of Quantum Chemistry by P.-O. Löwdin,A. Pullman Pdf

The Fourth International Congress in Quantum Chemistry under the auspices of the International Academy of Molecular Quantum Science in Menton, France was arranged at Uppsala University, Uppsala, Sweden, during the period June 14 - 19, 1982, in close collaboration with the University of Florida. The previous congresses were held in Menton 1973, New Orleans 1976, and Kyoto 1979, and the 1985 congress is tentatively planned to be held in the province of Quebec, Canada. The Congress consisted of six symposia in various areas of quantum chemistry, solid-state theory, and quantum bi ology. The meeting was attended by about 450 scientists from 45 different nations, and a total of more than 300 scientific papers were presented. Even the poster contri butions were given some plenary time. These proceedings contain the text of the plenary lec tures as well as the chairmen's introductions, whereas the contributed papers will be published in the International Journal of Quantum Chemistry, (John Wiley & Sons, New York) in the regular January - April 1983 issues.