Metals Fertility And Reproductive Toxicity

Author : Mari S. Golub
Publisher : CRC Press
Page : 288 pages
File Size : 40,8 Mb
Release : 2005-11-10
Category : Medical
ISBN : 1420023284

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Metals, Fertility, and Reproductive Toxicity by Mari S. Golub Pdf

Environmental endocrine disruptors have been at the heart of discussions about chemicals and their effects on fertility, but the focus has been on organic compounds and the role of metals has been largely overlooked - until now. Taking an organ-system-based approach, Metals, Fertility, and Reproductive Toxicity examines the effects of metals found in the everyday environment on fertility rates in humans and animal populations. This volume summarizes and evaluates the literature in the area of metal effects on fertility and reproduction in humans, laboratory animals, and wildlife. International experts have contributed chapters that explore how the ovary, testes, uterine system, and neuroendocrine system, among others, respond to metal exposure. Reviewing both current knowledge and cutting edge data, the chapters focus on either a particular metal or a particular population. A massive amount of data on this subject has been generated, summarized, and reviewed over the years. While there are many books available on metals toxicity and on reproductive toxicity, no current book explores both in the same volume. Culling information from throughout the literature, Metals, Fertility, and Reproductive Toxicity supplies an in-depth look at the role of metals in endocrine disruption and the spectrum of mechanisms involving metals that can influence reproduction.

Author : Tom Clarkson
Publisher : Springer Science & Business Media
Page : 830 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461593461

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Reproductive and Developmental Toxicity of Metals by Tom Clarkson Pdf

The Permanent Commission and International Association on Occupational Health (PCIAOH) established in 1969 a Subcommittee on the Toxicology of Metals under the chairmanship of Lars Friberg. This committee, which later was named the Scientific Committee on the Toxicology of Metals, has organized a number of previous meetings that have led to publications in three major areas of metal toxicology: a preliminary meeting in Slanchev Bryag, Bulgaria in- 1971, followed by a meeting in 1972 in Buenos Aires, Argentina which produced two reports (Dukes and Friberg, 1971; Task Group on Metal Accumulation, 1973), that discussed the metabolism of metals with special reference to absorption, excretion and biological half-times. The effects and dose-response relationships of toxic metals, including a discussion of general principles, was the second major topic addressed by the Scientific Committee at a meeting in Tokyo in 1974 (Nordberg, 1976). The philosophy of this conference, as well as the previous one in Buenos Aires, was based on the concept of a "threshold dose" for the occurrence of adverse effects. In a conference held in Atlanta, USA in 1980, the scope of discussion on metal effects was broadened to include the role of metals in carcinogenesis. Thus, for the first time, the Scientific Committee took under consideration the possibility of non-threshold relationships (Belman and Nordberg, 1981). In addition, the Scientific Committee on the Toxicology of Metals organized a workshop on metal interactions in Stockholm 1977 (Nordberg et al.

Author : Thomas W. Clarkson,Gunnar F. Nordberg,Polly R. Sager
Publisher : Unknown
Page : 864 pages
File Size : 52,5 Mb
Release : 1983-12
Category : Electronic
ISBN : 1461593476

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Reproductive and Developmental Toxicity of Metals by Thomas W. Clarkson,Gunnar F. Nordberg,Polly R. Sager Pdf

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee
Publisher : National Academies Press
Page : 476 pages
File Size : 55,5 Mb
Release : 1986-02-01
Category : Nature
ISBN : 9780309036870

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Drinking Water and Health, by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Board on Toxicology and Environmental Health Hazards,Safe Drinking Water Committee Pdf

The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 40,6 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author : Joseph E. Pizzorno,Michael T. Murray
Publisher : Unknown
Page : 0 pages
File Size : 54,9 Mb
Release : 1999
Category : Alternative medicine
ISBN : 0443059454

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Textbook of Natural Medicine by Joseph E. Pizzorno,Michael T. Murray Pdf

Introducing the most comprehensive, most thoroughly researched, most carefully referenced, and most up-to-date text on natural medicines and complementary modalities. It covers a wide range of tests and approaches for managing and treating over 100 conditions and health problems. Inside, readers will find accurate, detailed pharmacologic information on herbs and supplements, and crucial knowledge for making recommendations to patients.

Author : Suresh C Sikka,Wayne J.G. Hellstrom
Publisher : Academic Press
Page : 636 pages
File Size : 42,8 Mb
Release : 2017-11-14
Category : Medical
ISBN : 9780128013137

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Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health by Suresh C Sikka,Wayne J.G. Hellstrom Pdf

Bioenvironmental Issues Affecting Men's Reproductive and Sexual Health is structured into two parts related to men’s reproductive and sexual health with eight sections designed to enable a logical flow of such knowledge. The book is focused on the biology of key organs involved in male reproduction and the environmental influences affecting their functions with particular emphasis on clinical aspects. Individual chapters within the book range from basic to translational aspects, but all hold clinical relevance. This is an essential reference for those working and learning in the field of human reproduction, reproductive toxicology and environmental influences on reproductive and sexual health. Brings together the leading authorities working in the field of male reproduction and sexual health and how the environment affects these issues. Provides guidelines and reference values of various reproductive hormones, semen parameters, inclusion/exclusion criteria for clinical trials. Discover the most efficient methods by which to design clinical protocols for sperm safety studies and reproductive toxicology trials.

Author : Shanna H. Swan,Stacey Colino
Publisher : Simon and Schuster
Page : 304 pages
File Size : 48,8 Mb
Release : 2022-02-08
Category : Health & Fitness
ISBN : 9781982113674

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Count Down by Shanna H. Swan,Stacey Colino Pdf

An award-winning scientist, in this urgent, thought-provoking and meticulously researched book, shows how chemicals in the modern environment are changing--and endangering--human sexuality and fertility on the grandest scale.

Author : Robert E. Chapin
Publisher : Unknown
Page : 389 pages
File Size : 44,7 Mb
Release : 1993
Category : Electronic
ISBN : OCLC:657966284

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Male Reproductive Toxicology by Robert E. Chapin Pdf

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Subcommittee on Zinc Cadmium Sulfide
Publisher : National Academies Press
Page : 386 pages
File Size : 52,7 Mb
Release : 1997-05-30
Category : Nature
ISBN : 9780309174787

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Toxicologic Assessment of the Army's Zinc Cadmium Sulfide Dispersion Tests by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Subcommittee on Zinc Cadmium Sulfide Pdf

During the 1950s and 1960s, the U.S. Army conducted atmospheric dispersion tests in many American cities using fluorescent particles of zinc cadmium sulfide (ZnCdS) to develop and verify meteorological models to estimate the dispersal of aerosols. Upon learning of the tests, many citizens and some public health officials in the affected cities raised concerns about the health consequences of the tests. This book assesses the public health effects of the Army's tests, including the toxicity of ZnCdS, the toxicity of surrogate cadmium compounds, the environmental fate of ZnCdS, the extent of public exposures from the dispersion tests, and the risks of such exposures.

Author : Robert W. Kapp,Rochelle W. Tyl
Publisher : CRC Press
Page : 512 pages
File Size : 46,8 Mb
Release : 2016-04-19
Category : Medical
ISBN : 9781420073447

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Reproductive Toxicology, Third Edition by Robert W. Kapp,Rochelle W. Tyl Pdf

Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology’s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research. This ground-breaking resource includes: New and important critical mechanistic topics such as epigenetics and omics The first significant compilation of epigenetic mechanisms An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction New guidelines with respect to the latest research applications in the field

Author : Erma Z. Drobnis,Ajay K. Nangia
Publisher : Springer
Page : 325 pages
File Size : 45,5 Mb
Release : 2017-12-18
Category : Medical
ISBN : 9783319695358

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Impacts of Medications on Male Fertility by Erma Z. Drobnis,Ajay K. Nangia Pdf

The over-arching goal of this volume is to help infertility practitioners evaluate and manage their patients with poor semen quality. The authors review the existing literature on the effects of medications on male fertility, and provide detailed information about what is known, giving the number of individuals and population characteristics for studies of medication effects on male fertility. Medications are designed to treat illness and reduce symptoms, but all have undesirable adverse effects such as headache or stomach upset. Some adverse reactions can even be life-threatening, so it is no surprise that some drugs have negative effects on male reproduction. Medical practitioners rarely consider a man’s reproductive plans when prescribing medications. Men are routinely treated with drugs that can impair or abolish fertility. Although practitioners in the field of reproductive medicine generally realize that certain drugs impact negatively on reproductive health, there are limited resources providing evidence-based knowledge useful in counseling patients. Tables throughout this volume summarize the information for each drug, providing a handy reference for clinical use.

Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on Jet-Propulsion Fuel 8
Publisher : National Academies Press
Page : 229 pages
File Size : 51,9 Mb
Release : 2003-02-14
Category : Nature
ISBN : 0309168708

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Toxicologic Assessment of Jet-Propulsion Fuel 8 by National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Toxicology,Subcommittee on Jet-Propulsion Fuel 8 Pdf

This report provides a critical review of toxicologic, epidemiologic, and other relevant data on jet-propulsion fuel 8, a type of fuel in wide use by the U.S. Department of Defense (DOD), and an evaluation of the scientific basis of DOD’s interim permissible exposure level of 350 mg/m3

Author : Stefan S. du Plessis,Ashok Agarwal,Edmund S. Sabanegh, Jr.
Publisher : Springer
Page : 281 pages
File Size : 40,5 Mb
Release : 2014-07-26
Category : Health & Fitness
ISBN : 9781493910403

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Male Infertility by Stefan S. du Plessis,Ashok Agarwal,Edmund S. Sabanegh, Jr. Pdf

This unique text provides a comprehensive yet concise review of the various environmental factors and lifestyle choices which impact male fertility, with special emphasis on the mechanisms that contribute to decreased sperm production and impaired function. Internationally recognized scientists and clinicians, leaders in the field of infertility, gather their insights and discuss how to prevent, address and cure male infertility caused by factors such as smoking, alcohol consumption, medication and drug use, obesity, dietary and exercise habits, sexually transmitted infections, psychological stress and occupational exposure to chemicals and radiation. Written in an easy to follow, informal yet scientific style, Male Infertility offers invaluable clinical guidelines for physicians and infertility experts and new data and research of great interest to basic scientists, andrologists and embryologists.

Author : Eleanor Chelimsky
Publisher : DIANE Publishing
Page : 118 pages
File Size : 47,5 Mb
Release : 2000
Category : Electronic
ISBN : 0788186264

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Reproductive and Developmental Toxicants by Eleanor Chelimsky Pdf

Evaluates federal regulatory actions on environmental chemicals known to cause adverse reproductive and developmental outcomes. Identifies 30 environmental chemicals found to be of high concern because of the widespread acknowledgment of their reproductive and developmental consequences as toxicants. Determines the extent to which these chemicals are regulated by the federal government. Assesses the degree to which these regulatory actions are based on reproductive and developmental toxicity. Evaluates whether the regulatory protection currently provided to the public against reproductive and developmental disease is sufficient.