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Author : Cheng Guo,Gerard Bolbach,Lucrece Matheron,Kezhi Jiang,Lei Yue,Lin Wang
Publisher : Frontiers Media SA
Page : 120 pages
File Size : 44,9 Mb
Release : 2022-07-13
Category : Science
ISBN : 9782889764365
Author : Alisa G. Woods,Costel C. Darie
Publisher : Springer
Page : 813 pages
File Size : 40,5 Mb
Release : 2019-07-25
Category : Science
ISBN : 9783030159504
This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.
Author : Rainer Cramer
Publisher : Springer
Page : 286 pages
File Size : 48,6 Mb
Release : 2015-11-09
Category : Science
ISBN : 9783319048192
This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics
Author : Haroun N. Shah,Saheer E. Gharbia,Ajit J. Shah,Erika Y. Tranfield,K. Clive Thompson
Publisher : John Wiley & Sons
Page : 565 pages
File Size : 43,5 Mb
Release : 2023-06-06
Category : Science
ISBN : 9781119814054
Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry Detailed resource presenting the capabilities of MALDI mass spectrometry (MS) to industrially and environmentally significant areas in the biosciences Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry fulfills a need to bring the key analytical technique of MALDI mass spectrometric analysis into routine practice by specialists and non-specialists, and technicians. It informs and educates established researchers on the development of techniques as applied to industrially significant areas within the biosciences. Throughout the text, the reader is presented with recognized and emerging techniques of this powerful and continually advancing field of analytical science to key areas of importance. While many scientific papers are reporting new applications of MS-based analysis in specific foci, this book is unique in that it draws together an incredibly diverse range of applications that are pushing the boundaries of MS across the broad field of biosciences. Contributed to by recognized experts in the field of MALDI MS who have been key players in promoting the advancement and dissemination of authoritative information in this field, Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry covers sample topics such as: Oil microbiology, marine and freshwater ecosystems, agricultural and food microbiology, and industrial waste microbiology Bioremediation and landfill sites microbiology, microbiology of inhospitable sites (e.g. Arctic and Antarctic, and alkaline and acidic sites, and hot temperatures) Veterinary, poultry and animals, viral applications of MS, and antibiotic resistance using tandem MS methods Recent developments which are set to transform the use of MS from its success in clinical microbiology to a wide range of commercial and environmental uses Bridging the gap between measurement and key applications, this text is an ideal resource for industrial and environmental analytical scientists, including technologists in the food industry, pharmaceuticals, and agriculture, as well as biomedical scientists, researchers, clinicians and academics and scientists in bio-resource centers.
Author : Dominic M. Desiderio
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 43,7 Mb
Release : 2013-11-11
Category : Science
ISBN : 9781489911735
In response to the growing use of mass spectrometry in the clinical and biomedical fields, this book collects recent research involving electrospray ionization, neuronal systems, and structural modifications of proteins. The significant advances in instrumentation, methodology, experimentation presented herein will serve to expand the current concept of clinical mass spectrometry.
Author : Ottavia Giuffrè,Carlos Rey-Castro,Anna Napoli
Publisher : Frontiers Media SA
Page : 177 pages
File Size : 46,5 Mb
Release : 2021-07-05
Category : Science
ISBN : 9782889669783
Author : Robert K. Boyd,Cecilia Basic,Robert A. Bethem
Publisher : John Wiley & Sons
Page : 1179 pages
File Size : 47,5 Mb
Release : 2011-08-24
Category : Science
ISBN : 9781119964391
This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style
Author : Karoly Vekey,Andreas Telekes,Akos Vertes
Publisher : Elsevier
Page : 606 pages
File Size : 51,9 Mb
Release : 2011-08-11
Category : Science
ISBN : 9780080554655
Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine. The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry. * Guides the reader from basic principles and methods to cutting edge applications. * There is NO comparable book on the market to fill this fast growing field.
Author : Peter Ingram,John D. Shelburne,Victor L. Roggli,Ann LeFurgey
Publisher : Academic Press
Page : 545 pages
File Size : 50,8 Mb
Release : 1999-10-29
Category : Science
ISBN : 0080524567
Biomedical Applications of Microprobe Analysis is a combination reference/laboratory manual for the use of microprobe analysis in both clinical diagnostic and research settings. Also called microchemical microscopy, microprobe analysis uses high-energy bombardment of cells and tissue, in combination with high resolution EM or confocal microscopy to provide a profile of the ion, metal, and mineral concentrations present in a sample. This allows insight into the physiology and pathophysiology of a wide variety of cells and tissues. This book describes methods for obtaining detailed information about the identity and composition of particles too small to be seen with the naked eye and describes how this information can be useful in diagnostic and biomedical research. Up-to-date review of electron microprobe analysis Detailed descriptions of sample preparation techniques Recent technologies including confocal microscopy, infrared microspectroscopy, and laser raman spectroscopy Over 100 illustrations with numerous specific applications Contributions by world-renowned experts in the field Brief summary of highlights precedes each chapter
Author : Vincent S. Smentkowski
Publisher : Springer Science & Business Media
Page : 326 pages
File Size : 48,9 Mb
Release : 2014-03-18
Category : Science
ISBN : 9783319013602
This book summarizes the main surface analysis techniques that are being used to study biological specimens/systems. The compilation of chapters in this book highlight the benefits that surface analysis provides. The outer layer of bulk solid or liquid samples is referred to as the surface of the sample/material. At the surface, the composition, microstructure, phase, chemical bonding, electronic states, and/or texture is often different than that of the bulk material. The outer surface is where many material interactions/reactions take place. This is especially true biomaterials which may be fabricated into bio-devices and in turn implanted into tissues and organs. Surfaces of biomaterials (synthetic or modified natural materials) are of critical importance since the surface is typically the only part of the biomaterial/bio-device that comes in contact with the biological system. Analytical techniques are required to characterize the surface of biomaterials and quantify their impact in real-world biological systems. Surface analysis of biological materials started in the 1960’s and the number of researchers working in this area have increased very rapidly since then, a number of advances have been made to standard surface analytical instrumentation, and a number of new instruments have been introduced.
Author : Freddy Adams,Carlo Barbante
Publisher : Elsevier
Page : 480 pages
File Size : 48,9 Mb
Release : 2015-06-06
Category : Science
ISBN : 9780444634504
Chemical Imaging Analysis covers the advancements made over the last 50 years in chemical imaging analysis, including different analytical techniques and the ways they were developed and refined to link the composition and structure of manmade and natural materials at the nano/micro scale to the functional behavior at the macroscopic scale. In a development process that started in the early 1960s, a variety of specialized analytical techniques was developed – or adapted from existing techniques – and these techniques have matured into versatile and powerful tools for visualizing structural and compositional heterogeneity. This text explores that journey, providing a general overview of imaging techniques in diverse fields, including mass spectrometry, optical spectrometry including X-rays, electron microscopy, and beam techniques. Provides comprehensive coverage of analytical techniques used in chemical imaging analysis Explores a variety of specialized techniques Provides a general overview of imaging techniques in diverse fields
Author : Amir Al-Ahmed,Inamuddin
Publisher : Materials Research Forum LLC
Page : 202 pages
File Size : 46,9 Mb
Release : 2020-03-15
Category : Technology & Engineering
ISBN : 9781644900659
The book reports progress on the development of new biodegradable polymers, composites and nanocomposites for use in such areas as drug delivery, packaging, food and agricultural technology. The world has become increasingly worried about non-degradable polymers used in our daily activities. Hence, biodegradable polymers and composites are of growing demand to replace petroleum based polymers and products. Keywords: Biopolymers, Biodegradable Polymers, Biodegradable Composites, Biodegradable Nanocomposites, Green Composites, Biodegradable Packaging, Bioplastics, Biodegradation Test Methods, Polyhydroxybutyrate, Lipids, Liposomes, Lipid Composites, Natural Fiber, Drug Delivery, Dunnage, Electronics Packaging, Horticulture, Plantable Pots.
Author : Robert K. Boyd
Publisher : Wiley
Page : 1610 pages
File Size : 51,5 Mb
Release : 2010-08-23
Category : Science
ISBN : 0470952210
This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposesWritten in textbook style to facilitate understanding of this topicPresents fundamentals and real-world examples in a 'learning-though-doing' style
Author : Evgeny Katz,Jan Halámek
Publisher : John Wiley & Sons
Page : 446 pages
File Size : 45,8 Mb
Release : 2016-03-08
Category : Medical
ISBN : 9783527693528
Concentrating on the natural science aspects of forensics, top international authors from renowned universities, institutes, and laboratories impart the latest information from the field. In doing so they provide the background needed to understand the state of the art in forensic science with a focus on biological, chemical, biochemical, and physical methods. The broad subject coverage includes spectroscopic analysis techniques in various wavelength regimes, gas chromatography, mass spectrometry, electrochemical detection approaches, and imaging techniques, as well as advanced biochemical, DNA-based identification methods. The result is a unique collection of hard-to-get data that is otherwise only found scattered throughout the literature.
Author : G. Piemonte,F. Tagliaro,M. Marigo
Publisher : Springer
Page : 329 pages
File Size : 44,6 Mb
Release : 2013-08-21
Category : Medical
ISBN : 1489935274
The papers collected in this volume were presented at an International Conference that, with the same heading, was held at the Verona University, Italy, in June 1986. The meeting was organized by the Institute of Forensic Hedicine and the Laboratory of Medical Research of the University in cooperation with the Italian Group for Mass Spectrometry in Biochemistry and Medicine. The aim of the symposium was bringing together people, work ing in different branches of the wide field of modern analytical sciences, for promoting inter-disciplinary discussions and exchange of experiences. Actually it was felt that most of the analytical problems that very often have to be faced in quite different fields (chem istry, pharmacology, medicine, biology) have similar solutions, that could be made much easier by closer contac'cs among researches of these disciplines. Original papers and invited rewiews presented during the 3 days of the conference by leading experts gave an up-to-date outline of the modern analytical methods applied in pharmaceuti cal, biomedical and forensic sciences and a glimpse of the future perspectives.