Microbial Biofilms In Healthcare

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Microbial Biofilms in Healthcare

Author : Karen Vickery
Publisher : MDPI
Page : 166 pages
File Size : 48,6 Mb
Release : 2020-03-16
Category : Medical
ISBN : 9783039284108

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Microbial Biofilms in Healthcare by Karen Vickery Pdf

Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Microbial Biofilms in Healthcare: Formation, Prevention and Treatment

Author : Karen Vickery
Publisher : Unknown
Page : 166 pages
File Size : 53,7 Mb
Release : 2020
Category : Biology (General)
ISBN : 3039284118

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Microbial Biofilms in Healthcare: Formation, Prevention and Treatment by Karen Vickery Pdf

Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Biofilms in Infection Prevention and Control

Author : Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle
Publisher : Academic Press
Page : 394 pages
File Size : 53,6 Mb
Release : 2014-01-30
Category : Science
ISBN : 9780123977519

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Biofilms in Infection Prevention and Control by Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle Pdf

Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. Provides specific procedures for controlling and preventing infection Includes case studies of HCAI, and identifies appropriate treatments Presents national government standards for infection prevention and control Includes extensive references and links to websites for further information

Microbial Biofilms

Author : Mahmoud Ghannoum,Matthew Parsek,Marvin Whiteley,Pranab K. Mukherjee
Publisher : John Wiley & Sons
Page : 608 pages
File Size : 47,6 Mb
Release : 2015-10-01
Category : Science
ISBN : 9781683673330

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Microbial Biofilms by Mahmoud Ghannoum,Matthew Parsek,Marvin Whiteley,Pranab K. Mukherjee Pdf

An examination of the research and translational application to prevent and treat biofilm-associated diseases In the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense. Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically, Microbial Biofilms provides state-of-the-art research in the field of bacterial and fungal biofilms detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms future areas of research and their translational and clinical applications Microbial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.

The Role of Biofilms in Device-Related Infections

Author : Mark Shirtliff,Jeff G. Leid
Publisher : Springer Science & Business Media
Page : 276 pages
File Size : 47,8 Mb
Release : 2008-12-19
Category : Medical
ISBN : 9783540681199

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The Role of Biofilms in Device-Related Infections by Mark Shirtliff,Jeff G. Leid Pdf

Approximately 60% of all hospital-associated infections, over one million cases per year, are due to biofilms that have formed on indwelling medical devices. Device-related biofilm infections increase hospital stays and add over one billion dollars/year to U.S. hospitalization costs. Since the use and the types of indwelling medical devices commonly used in modern healthcare are continuously expanding, especially with an aging population, the incidence of biofilm infections will also continue to rise. The central problem with microbial biofilm infections of foreign bodies is their propensity to resist clearance by the host immune system and all antimicrobial agents tested to date. In fact, compared to their free floating, planktonic counterparts, microbes within a biofilm are 50 – 500 times more resistant to antimicrobial agents. Therefore, achieving therapeutic and non-lethal dosing regimens within the human host is impossible. The end result is a conversion from an acute infection to one that is persistent, chronic, and recurrent, most often requiring device removal in order to eliminate the infection. This text will describe the major types of device-related infections, and will explain the host, pathogen, and the unique properties of their interactions in order to gain a better understanding of these recalcitrant infections.

Biofilm-based Healthcare-associated Infections

Author : Gianfranco Donelli
Publisher : Springer
Page : 197 pages
File Size : 41,9 Mb
Release : 2014-11-10
Category : Medical
ISBN : 9783319097824

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Biofilm-based Healthcare-associated Infections by Gianfranco Donelli Pdf

The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.

Medical Biofilms

Author : Jana Jass,Susanne Surman,James Walker
Publisher : John Wiley & Sons
Page : 328 pages
File Size : 48,8 Mb
Release : 2003-04-02
Category : Science
ISBN : 0471988677

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Medical Biofilms by Jana Jass,Susanne Surman,James Walker Pdf

Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality. This will be the first book dedicated to medical biofilms. It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.

Microbial Biofilms

Author : Gianfranco Donelli
Publisher : Humana Press
Page : 380 pages
File Size : 53,5 Mb
Release : 2014-03-25
Category : Science
ISBN : 1493904663

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Microbial Biofilms by Gianfranco Donelli Pdf

The discovery that most of the chronic infections in humans, including the oral, lung, vaginal and foreign body-associated infections, are biofilm-based, has prompted the need to design new and properly focused preventive and therapeutic strategies for these diseases. Microbial Biofilms: Methods and Protocols provides a detailed description of the currently available methods and protocols to investigate bacterial and fungal biofilms, exhaustively illustrated and critically annotated in 25 chapters written by authors well known for their experience in the respective fields. The book has joined together microbiologists and specialists in infectious diseases, hygiene and public health involved in exploring different aspects of microbial biofilms as well as in designing new methods and/or developing innovative laboratory protocols. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Microbial Biofilms: Methods and Protocols presents readers with the most established and validated experimental procedures to investigate microbial biofilms.

Practical Handbook of Microbiology

Author : Lorrence H Green,Emanuel Goldman
Publisher : CRC Press
Page : 2032 pages
File Size : 43,8 Mb
Release : 2021-05-04
Category : Science
ISBN : 9781000245035

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Practical Handbook of Microbiology by Lorrence H Green,Emanuel Goldman Pdf

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise knowledge and practical information about working with microorganisms. Useful to anyone interested in microbes, the book is intended to especially benefit four groups: trained microbiologists working within one specific area of microbiology; people with training in other disciplines, and use microorganisms as a tool or "chemical reagent"; business people evaluating investments in microbiology focused companies; and an emerging group, people in occupations and trades that might have limited training in microbiology, but who require specific practical information. Key Features Provides a comprehensive compendium of basic information on microorganisms—from classical microbiology to genomics. Includes coverage of disease-causing bacteria, bacterial viruses (phage), and the use of phage for treating diseases, and added coverage of extremophiles. Features comprehensive coverage of antimicrobial agents, including chapters on anti-fungals and anti-virals. Covers the Microbiome, gene editing with CRISPR, Parasites, Fungi, and Animal Viruses. Adds numerous chapters especially intended for professionals such as healthcare and industrial professionals, environmental scientists and ecologists, teachers, and businesspeople. Includes comprehensive survey table of Clinical, Commercial, and Research-Model bacteria. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license. Chapter 21, "Archaea," of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license available at http://www.taylorfrancis.com See Emanuel Goldman's Open Access article: "Lamarck redux and other false arguments against SARS-CoV-2 vaccination," https://www.embopress.org/doi/full/10.15252/embr.202254675

Biofilm-based Healthcare-associated Infections

Author : Gianfranco Donelli
Publisher : Springer
Page : 193 pages
File Size : 40,5 Mb
Release : 2014-11-03
Category : Medical
ISBN : 9783319110387

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Biofilm-based Healthcare-associated Infections by Gianfranco Donelli Pdf

The aim of this book is to provide readers with a wide overview of the main healthcare-associated infections caused by bacteria and fungi able to grow as biofilm. The recently acquired knowledge on the pivotal role played by biofilm-growing microorganisms in healthcare-related infections has given a new dynamic to detection, prevention and treatment of these infections in patients admitted to both acute care hospitals and long-term care facilities. Clinicians, hygienists and microbiologists will be updated by leading scientists on the state-of-art of biofilm-based infections and on the most innovative strategies for prevention and treatment of these infections, often caused by emerging multidrug-resistant biofilm-growing microorganisms.

Oral Biofilms

Author : S. Eick
Publisher : Karger Medical and Scientific Publishers
Page : 247 pages
File Size : 45,6 Mb
Release : 2020-12-21
Category : Medical
ISBN : 9783318068528

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Oral Biofilms by S. Eick Pdf

Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.

New Insights on Biofilm Antimicrobial Strategies

Author : Luís Melo,Nuno F. Azevedo
Publisher : MDPI
Page : 264 pages
File Size : 44,7 Mb
Release : 2021-08-17
Category : Medical
ISBN : 9783036512211

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New Insights on Biofilm Antimicrobial Strategies by Luís Melo,Nuno F. Azevedo Pdf

Over the last few decades, the study of microbial biofilms has been gaining interest among the scientific community. These microbial communities comprise cells adhered to surfaces that are surrounded by a self-produced exopolymeric matrix that protects biofilm cells against different external stresses. Biofilms can have a negative impact on different sectors within society, namely in agriculture, food industries, and veterinary and human health. As a consequence of their metabolic state and matrix protection, biofilm cells are very difficult to tackle with antibiotics or chemical disinfectants. Due to this problem, recent advances in the development of antibiotic alternatives or complementary strategies to prevent or control biofilms have been reported. This book includes different strategies to prevent biofilm formation or to control biofilm development and includes full research articles, reviews, a communication, and a perspective.

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms

Author : Mukesh Kumar Yadav,Bhim Pratap Singh
Publisher : Elsevier
Page : 324 pages
File Size : 42,7 Mb
Release : 2019-10-10
Category : Technology & Engineering
ISBN : 9780444642806

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New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms by Mukesh Kumar Yadav,Bhim Pratap Singh Pdf

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms is divided into three sections: microbial adhesion/biofilms in medical settings, microbial adhesion/biofilms in agriculture, and microbial adhesion/biofilm in the environment and industry. Chapters cover adhesion and biofilm formation by pathogenic microbes on tissue and on indwelling medical devices, including sections on human infections, microbial communication during biofilm mode of growth, host defense and antimicrobial resistance, and more. Other sections cover the biofilms of agriculturally important and environmental friendly microbes, including biofilm formation on plants, in soil, and in aquatic environments. Finally, the latest scientific research on microbial adhesion and biofilm formation in the environment and in industry is covered. Provides an overview on the growth, structure, cell-to-cell interactions, and control/dispersal of bacterial and fungal of in vitro and in vivo biofilms Presents an overview on the microbial adhesion, biofilm formation and structures of single-species and multi-species biofilms on human tissues/medical devices, agriculture, environment and chemical industries Includes chapters on microbial biofilms of pathogenic microbes on human tissues and in medical indwelling devices Covers factors affecting microbial biofilm, adhesion and formation

Bacterial Biofilms

Author : Sadik Dincer,Melis Sümengen Özdenefe,Afet Arkut
Publisher : BoD – Books on Demand
Page : 362 pages
File Size : 52,9 Mb
Release : 2020-10-07
Category : Science
ISBN : 9781789858990

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Bacterial Biofilms by Sadik Dincer,Melis Sümengen Özdenefe,Afet Arkut Pdf

This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.

Biofilms in Plant and Soil Health

Author : Iqbal Ahmad,Fohad Mabood Husain
Publisher : John Wiley & Sons
Page : 568 pages
File Size : 49,7 Mb
Release : 2017-07-14
Category : Science
ISBN : 9781119246411

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Biofilms in Plant and Soil Health by Iqbal Ahmad,Fohad Mabood Husain Pdf

Biofilms are predominant mode of life for microbes under natural conditions. The three-dimensional structure of the biofilm provides enhanced protection from physical, chemical and biological stress conditions to associated microbial communities. These complex and highly structured microbial communities play a vital role in maintaining the health of plants, soils and waters. Biofilm associated with plants may be pathogenic or beneficial based on the nature of their interactions. Pathogenic or undesirable biofilm requires control in many situations, including soil, plants, food and water. Written by leading experts from around the world, Biofilms in Plant and Soil Health provides an up-to-date review on various aspects of microbial biofilms, and suggests future and emerging trends in biofilms in plant and soil health. Issues are addressed in four sub areas: I) The fundamentals and significance of biofilm in plant and soil health, and the concept of mono and mixed biofilms by PGPR and fungal biofilms. II) Biochemical and molecular mechanisms in biofilm studies in plant associated bacteria, and techniques in studying biofilms and their characterization, gene expression and enhanced antimicrobial resistance in biofilms, as well as biotic and biotic factors affecting biofilm in vitro. III) The ecological significance of soil associated biofilms and stress management and bioremediation of contaminated soils and degraded ecosystems. IV) Pathogenic biofilm associated with plant and food and its control measures. This book is recommended for students and researchers working in agricultural and environmental microbiology, biotechnology, soil sciences, soil and plant health and plant protection. Researchers working in the area of quorum sensing, biofilm applications, and understanding microbiome of soil and plants will also find it useful.