Microbiota Brain Axis

Author : Jane Foster,Gerard Clarke
Publisher : Academic Press
Page : 280 pages
File Size : 41,5 Mb
Release : 2024-03-01
Category : Medical
ISBN : 9780128148013

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Microbiota Brain Axis by Jane Foster,Gerard Clarke Pdf

Microbiota Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct effective microbiota-brain research, understand the appropriate methodologies, and collect and analyze microbiota data. The book begins with an introduction to the importance of the microbiota-brain communication in development and how microbiota impact neurodevelopmental disorders, mental health and neurodegeneration. In addition, the book discusses advances in microbiota analysis tools and techniques for neuroscience related research. Reviews the many approaches to manipulating the microbiota in animal studies - including the use of germ-free animals, antibiotics and diet - and covers the strengths and limitations of each Outlines available microbiota research tools, such as 16S sequencing and shot-gun metagenomics Provides a comprehensive guide to analyzing microbiota-related data and the many choices for bioinformatics

Author : Niall Hyland,Catherine Stanton
Publisher : Elsevier
Page : 544 pages
File Size : 52,8 Mb
Release : 2023-12-15
Category : Medical
ISBN : 9780323983020

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The Gut-Brain Axis by Niall Hyland,Catherine Stanton Pdf

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition presents the most advances on how the gut microbiome influences central nervous system and brain function introduced in the first edition. The book also describes how environmental influences which affect the microbiota, including, diet, exercise, and early-life, impact on the gut-brain axis. The second edition contains new chapters on metabolomics and the gut-brain-axis; dietary factors in the maintenance of a healthy brain ; the role of gut microbes in neurodegenerative disorders; the link between exercise and the gut-brain-axis; and infant Nutrition, the microbiome and neurodevelopment. In addition, the second edition presents coverage of mechanisms underlying neurological disease; approaches to investigate the role of the microbiome in brain and behavior, and 'next generation' probiotics and prebiotics. The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition continues to be the “go-to resource for further exploration of the microbiota. Includes new chapters focused on metabolomics and the gut-brain axis; dietary polyphenols to maintain healthier brain measures and cognitive function; the role of gut microbes in Parkinson’s Disease; the microbiota-gut-brain axis in psychosis; exploration of exercise and the gut-brain axis; and coverage of pediatric nutrition Updated chapters reflect on the most recent advances on the role of the microbiome and gut-brain axis in early-life, aging, cognition, metabolism, neurodevelopmental disorders, as well as on the enteric nervous system Addresses the role of diet and the gut-brain axis across several chapters with unique author insights and perspectives Examines common mechanisms and pathways by which the microbiota may influence brain and behavior Discusses strategies to explore the contribution of the microbiome to the gut-brain axis; methods to enhance therapeutic strategies targeted toward the microbiota; and presents a case study demonstrating a rational screening approach to increase translational success

Author : Mark Lyte,John F. Cryan
Publisher : Springer
Page : 436 pages
File Size : 45,5 Mb
Release : 2014-07-05
Category : Science
ISBN : 9781493908974

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Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease by Mark Lyte,John F. Cryan Pdf

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Author : Alper Evrensel,Barış Önen Ünsalver
Publisher : BoD – Books on Demand
Page : 115 pages
File Size : 46,7 Mb
Release : 2018-12-12
Category : Science
ISBN : 9781789848144

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Gut Microbiota by Alper Evrensel,Barış Önen Ünsalver Pdf

The gut-brain axis has gained considerable attention from different branches of the scientific community in recent years. In this book, scientists from different disciplines present current scientific knowledge on the topic. The interaction between the prokaryote and eukaryote cells stimulates the evolutionary processes, and results in various systemic illnesses such as neuropsychiatric disorders and may help the continuity of health. Nature has provided us with healthy food that builds our pharmacy. This natural pharmacy store may help the body's healing processes through its effects on gut microbiota and the immune system. This book aims to provide the reader with detailed analyses of the current scientific knowledge on the gut-brain axis and its relation with health and disease. We hope that the reader benefits from the presented material.

Author : Andreas M. Grabrucker
Publisher : Unknown
Page : 117 pages
File Size : 54,9 Mb
Release : 2021
Category : Electronic
ISBN : OCLC:1280592589

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Autism Spectrum Disorders by Andreas M. Grabrucker Pdf

Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.

Author : Mark Lyte,Primrose P.E. Freestone
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 45,6 Mb
Release : 2010-04-06
Category : Medical
ISBN : 9781441955760

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Microbial Endocrinology by Mark Lyte,Primrose P.E. Freestone Pdf

Microbial endocrinology represents a newly emerging interdisciplinary field that is formed by the intersection of the fields of neurobiology and microbiology. This book will introduce a new perspective to the current understanding not only of the factors that mediate the ability of microbes to cause disease, but also to the mechanisms that maintain normal homeostasis. The discovery that microbes can directly respond to neuroendocrine hormones, as evidenced by increased growth and production of virulence-associated factors, provides for a new framework with which to investigate how microorganisms interface not only with vertebrates, but also with invertebrates and even plants. The reader will learn that the neuroendocrine hormones that one most commonly associates with mammals are actually found throughout the plant, insect and microbial communities to an extent that will undoubtedly surprise many, and most importantly, how interactions between microbes and neuroendocrine hormones can influence the pathophysiology of infectious disease.

Author : Francesca Ronchi,Raffaella Gozzelino,Lloyd Kasper
Publisher : Frontiers Media SA
Page : 141 pages
File Size : 48,5 Mb
Release : 2022-06-28
Category : Medical
ISBN : 9782889764396

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Gut Microbiota-Brain Axis in Enteric and Central Neuronal Functions in Health and Neuropsychiatric Disorders by Francesca Ronchi,Raffaella Gozzelino,Lloyd Kasper Pdf

Topic Editor Dr. Kasper is co-founder of Symbiotix Biotherapeutics. The other Topic Editors declare no competing interests with regards to the Research Topic theme.

Author : C.S.M. Cowan,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Page : 158 pages
File Size : 51,6 Mb
Release : 2021-05-06
Category : Medical
ISBN : 9783318068566

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Microbes and the Mind by C.S.M. Cowan,B.E. Leonard Pdf

Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.

Author : R. Z. Sayyed,Mahejibin Khan
Publisher : Springer Nature
Page : 443 pages
File Size : 54,5 Mb
Release : 2022-01-03
Category : Science
ISBN : 9789811616266

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Microbiome-Gut-Brain Axis by R. Z. Sayyed,Mahejibin Khan Pdf

The book highlights the importance of prebiotics, probiotics and synbiotics in the signalling mechanism between gut microbiota and brain, also referred to as the gut-brain axis. A stable gut microbiota is essential for normal gut physiology and overall health, since it assists in proper signalling along the brain–gut axis. The book describes how the cross talks between gut microbiota and brain, not only regulate gastro-intestinal functions but also ensure proper functioning of cognitive behaviour and immunological functions. The various chapters describe probiotic microorganisms that colonize gastrointestinal tract and provide an array of health benefits to the host. It further elaborates about certain non-digestible oligosaccharides (prebiotics) are easily fermented by specialist microbes in the gut, to produce health-promoting metabolites and inhibit the growth of pathogenic bacteria. This book is useful for students, researchers and scientists in the field of microbiology, food science and nutrition. It is also meant for industry experts involved in developing nutraceuticals.

Author : Adrien A Eshraghi
Publisher : World Scientific
Page : 396 pages
File Size : 44,8 Mb
Release : 2021-11-03
Category : Science
ISBN : 9789811221163

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Gut-brain Connection, Myth Or Reality?: Role Of The Microbiome In Health And Diseases by Adrien A Eshraghi Pdf

In this book the recent advancements in understanding the gut-brain interaction as well as gut microbiome and how this interaction plays a vital role in human health and disease are discussed. Each chapter gives an analysis of questions, research directions, and methods within the field of gut-brain axis. The readers will benefit from the latest knowledge about our understanding about how gut-brain axis and modulation of gut microbiome determines predisposition to neurological disorders. The multidisciplinary book is essential reading for anyone interested in the field of gut-brain axis and gut microbiome: from undergraduates to graduate students as well as scientists and physicians having an interest in the new exciting field of gut microbiome and its relationship with brain function.

Author : Markus Wöhr,Sören Krach
Publisher : Springer
Page : 429 pages
File Size : 40,9 Mb
Release : 2017-01-31
Category : Medical
ISBN : 9783319474298

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Social Behavior from Rodents to Humans by Markus Wöhr,Sören Krach Pdf

This compelling volume provides a broad and accessible overview on the rapidly developing field of social neuroscience. A major goal of the volume is to integrate research findings on the neural basis of social behavior across different levels of analysis from rodent studies on molecular neurobiology to behavioral neuroscience to fMRI imaging data on human social behavior.

Author : Amit Kumar Tripathi,Malini Kotak
Publisher : Springer Nature
Page : 315 pages
File Size : 51,8 Mb
Release : 2022-08-03
Category : Medical
ISBN : 9789811945304

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Gut Microbiome in Neurological Health and Disorders by Amit Kumar Tripathi,Malini Kotak Pdf

This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.

Author : Hesong Wang,Xueqin Ni,Yang Bai
Publisher : Frontiers Media SA
Page : 149 pages
File Size : 44,7 Mb
Release : 2023-06-29
Category : Science
ISBN : 9782832527115

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The role of gut microbiota and probiotics in modulating gut-brain axis of humans and animals by Hesong Wang,Xueqin Ni,Yang Bai Pdf

Author : Emeran Mayer
Publisher : HarperCollins
Page : 336 pages
File Size : 55,5 Mb
Release : 2018-06-05
Category : Psychology
ISBN : 9780062846822

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The Mind-Gut Connection by Emeran Mayer Pdf

Cutting-edge neuroscience combines with the latest discoveries on the human microbiome to inform this practical guide that proves once and for all the inextricable, biological link between mind and body. We have all experienced the connection between our mind and our gut—the decision we made because it “felt right;” the butterflies in our stomach before a big meeting; the anxious stomach rumbling when we’re stressed out. While the dialogue between the gut and the brain has been recognized by ancient healing traditions, including Aryuvedic and Chinese medicine, Western medicine has failed to appreciate the complexity of how the brain, gut, and more recently, the microbiome—the microorganisms that live inside us—communicate with one another. In The Mind-Gut Connection, Dr. Emeran Mayer, Executive Director of the UCLA Center for Neurobiology of Stress, offers a revolutionary look at this developing science, teaching us how to harness the power of the mind-gut connection to take charge of our health. The Mind-Gut Connection, shows how to keep the communication brain-gut communication clear and balanced to: • Heal the gut by focusing on a plant-based diet • Balance the microbiome by consuming fermented foods and probiotics, fasting, and cutting out sugar and processed foods • Promote weight loss by detoxifying and creating a healthy digestion and maximum nutrient absorption • Boost immunity and prevent the onset of neurological diseases such as Parkinson’s and Alzheimer’s • Generate a happier mindset and reduce fatigue, moodiness, anxiety, and depression • Prevent and heal GI disorders such as leaky gut syndrome; food sensitivities and allergies; and IBS; as well as digestive discomfort such as heartburn and bloating • And much more. Supplemental enhancement PDF accompanies the audiobook.

Author : G.M. Pasinetti
Publisher : IOS Press
Page : 732 pages
File Size : 51,7 Mb
Release : 2022-07-05
Category : Medical
ISBN : 9781643682891

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Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease by G.M. Pasinetti Pdf

Despite being confined to the gastrointestinal tract, the gut microbiome has a wide impact on human physiology, supplementing its host’s biochemistry in a complex symbiotic relationship. Research in the field has evolved rapidly in the last decade, and we are now developing a better understanding of how our gut microbiome can influence our immune systems, metabolism, neurological signaling, and perhaps most unexpectedly, our brains; a phenomenon described as the gut-brain-axis. This book, ‘Handbook of Microbiome and Gut-Brain-Axis in Alzheimer’s Disease’, sets out to explore the complex role of the microbiome with regard to Alzheimer’s disease (AD). The microbiome is a critical and often overlooked aspect of immunity, which in turn plays a role in cognition. The book presents current research into the gut microbiota and its far-reaching impacts on cognitive function and neurodegeneration. Interventions, including probiotic supplementation, fecal transfer, and supplementation with microbial metabolites, are discussed, as is the use of certain probiotics to study the effects of the gut microbiota on behavior and cognitive function, and as potential therapeutics for AD. Other topics covered include the influence of the gut and oral microbiota on immune inflammatory signals: cytokines, neuroendocrine hormones, bacterial components, neuroactive molecules, and microbial metabolites. The book is divided into four sections, each covering a research area pertinent to the gut-brain-axis and its relationship with cognitive function and AD. It will be of interest to all those whose work includes the study and understanding of these complex, multi-variable biological mechanisms, particularly in the context of cognitive function and AD. The cover shows a color edited MRI image of a sagittal section of a neurological control brain of Dr. Giulio Maria Pasinetti.