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Microsystem Engineering of Lab-on-a-chip Devices by Oliver Geschke,Henning Klank,Pieter Telleman Pdf
Written by an interdisciplinary team of chemists, biologists and engineers from one of the leading European centers for microsystem research, MIC in Lyngby, Denmark, this book introduces and discusses the different aspects of (bio)chemical microsystem development. Unlike other, far more voluminous and theoretical books on this topic, this is a concise, practical handbook, dealing with analytical applications, particularly in the life sciences. Topics include: * microfluidics * silicon micromachining * glass and polymer micromachining * packaging * analytical chemistry illustrated with examples taken mainly from ongoing research projects at MIC.
Lab-on-a-Chip Devices and Micro-Total Analysis Systems by Jaime Castillo-León,Winnie E. Svendsen Pdf
This book covers all the steps in order to fabricate a lab-on-a-chip device starting from the idea, the design, simulation, fabrication and final evaluation. Additionally, it includes basic theory on microfluidics essential to understand how fluids behave at such reduced scale. Examples of successful histories of lab-on-a-chip systems that made an impact in fields like biomedicine and life sciences are also provided. This book also: · Provides readers with a unique approach and toolset for lab-on-a-chip development in terms of materials, fabrication techniques, and components · Discusses novel materials and techniques, such as paper-based devices and synthesis of chemical compounds on-chip · Covers the four key aspects of development: basic theory, design, fabrication, and testing · Provides readers with a comprehensive list of the most important journals, blogs, forums, and conferences where microfluidics and lab-on-a-chip news, methods, techniques and challenges are presented and discussed, as well as a list of companies providing design and simulation support, components, and/or developing lab-on-a-chip and microfluidic devices.
HereOCOs a groundbreaking book that introduces and discusses the important aspects of lab-on-a-chip, including the practical techniques, circuits, microsystems, and key applications in the biomedical, biology, and life science fields. Moreover, this volume covers ongoing research in lab-on-a-chip integration and electric field imaging. Presented in a clear and logical manner, the book provides you with the fundamental underpinnings of lab-on-a-chip, presents practical results, and brings you up to date with state-of-the-art research in the field. This unique resource is supported with over 160 illustrations that clarify important topics throughout.
Handbook of Green Analytical Chemistry by Miguel de la Guardia,Salvador Garrigues Pdf
The emerging field of green analytical chemistry is concerned with the development of analytical procedures that minimize consumption of hazardous reagents and solvents, and maximize safety for operators and the environment. In recent years there have been significant developments in methodological and technological tools to prevent and reduce the deleterious effects of analytical activities; key strategies include recycling, replacement, reduction and detoxification of reagents and solvents. The Handbook of Green Analytical Chemistry provides a comprehensive overview of the present state and recent developments in green chemical analysis. A series of detailed chapters, written by international specialists in the field, discuss the fundamental principles of green analytical chemistry and present a catalogue of tools for developing environmentally friendly analytical techniques. Topics covered include: Concepts: Fundamental principles, education, laboratory experiments and publication in green analytical chemistry. The Analytical Process: Green sampling techniques and sample preparation, direct analysis of samples, green methods for capillary electrophoresis, chromatography, atomic spectroscopy, solid phase molecular spectroscopy, derivative molecular spectroscopy and electroanalytical methods. Strategies: Energy saving, automation, miniaturization and photocatalytic treatment of laboratory wastes. Fields of Application: Green bioanalytical chemistry, biodiagnostics, environmental analysis and industrial analysis. This advanced handbook is a practical resource for experienced analytical chemists who are interested in implementing green approaches in their work.
Lab-on-a-Chip Fabrication and Application by Margarita Stoytcheva,Roumen Zlatev Pdf
The necessity of on-site, fast, sensitive, and cheap complex laboratory analysis, associated with the advances in the microfabrication technologies and the microfluidics, made it possible for the creation of the innovative device lab-on-a-chip (LOC), by which we would be able to scale a single or multiple laboratory processes down to a chip format. The present book is dedicated to the LOC devices from two points of view: LOC fabrication and LOC application.
Microfluidics and Lab-on-a-Chip by Andreas Manz,Giuseppina Simone,Jonathan S. O'Connor,Pavel Neuzil Pdf
Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.
Environmental Analysis by Electrochemical Sensors and Biosensors by Ligia Maria Moretto,Kurt Kalcher Pdf
This book presents an exhaustive overview of electrochemical sensors and biosensors for the analysis and monitoring of the most important analytes in the environmental field, in industry, in treatment plants and in environmental research. The chapters give the reader a comprehensive, state-of-the-art picture of the field of electrochemical sensors suitable to environmental analytes, from the theoretical principles of their design to their implementation, realization and application. The first three chapters discuss fundamentals, and the last three chapters cover the main groups of analytes of environmental interest.
Microfluidics and Lab-on-a-chip by Andreas Manz,Pavel Neužil,Jonathan S O'Connor,Giuseppina Simone Pdf
Microfluidic technology is revolutionising a number of scientific fields, including chemistry, biology, diagnostics, and engineering. The ability to manipulate fluids and objects within networks of micrometre-scale channels allows reductions in processing and analysis times, reagent and sample consumption, and waste production, whilst allowing fine control and monitoring of chemical or biological processes. The integration of multiple components and processes enable “lab-on-a-chip” devices and “micro total analysis systems” that have applications ranging from analytical chemistry, organic synthesis, and clinical diagnostics to cell biology and tissue engineering. This concise, easy-to-read book is perfectly suited for instructing newcomers on the most relevant and important aspects of this exciting and dynamic field, particularly undergraduate and postgraduate students embarking on new studies, or for those simply interested in learning about this widely applicable technology. Written by a team with more than 20 years of experience in microfluidics research and teaching, the book covers a range of topics and techniques including fundamentals (e.g. scaling laws and flow effects), microfabrication and materials, standard operations (e.g. flow control, detection methods) and applications. Furthermore, it includes questions and answers that provide for the needs of students and teachers in the area.
Labs on Chip: Principles, Design and Technology provides a complete reference for the complex field of labs on chip in biotechnology. Merging three main areas— fluid dynamics, monolithic micro- and nanotechnology, and out-of-equilibrium biochemistry—this text integrates coverage of technology issues with strong theoretical explanations of design techniques. Analyzing each subject from basic principles to relevant applications, this book: Describes the biochemical elements required to work on labs on chip Discusses fabrication, microfluidic, and electronic and optical detection techniques Addresses planar technologies, polymer microfabrication, and process scalability to huge volumes Presents a global view of current lab-on-chip research and development Devotes an entire chapter to labs on chip for genetics Summarizing in one source the different technical competencies required, Labs on Chip: Principles, Design and Technology offers valuable guidance for the lab-on-chip design decision-making process, while exploring essential elements of labs on chip useful both to the professional who wants to approach a new field and to the specialist who wants to gain a broader perspective.
Microfluidics for Cellular Applications by Gerardo Perozziello,Ulrich Kruhne,Paola Luciani Pdf
Microfluidics for Cellular Applications describes microfluidic devices for cell screening from a physical, technological and applications point-of-view, presenting a comparison with the cell microenvironment and conventional instruments used in medicine. Microfluidic technologies, protocols, devices for cell screening and treatment have reached an advanced state but are mainly used in research. Sections break them down into practical applications and conventional medical procedures and offers insights and analysis on how higher resolutions and fast operations can be reached. This is an important resource for those from an engineering and technology background who want to understand more and gain additional insights on cell screening processes. Outlines the major applications of microfluidic devices in medicine and biotechnology Assesses the major challenges of using microfluidic devices in terms of complexity of the control set-up, ease of use, integration capability, automation level, analysis throughput, content and costs Describes the major fabrication techniques for assembling effective microfluidic devices for bioapplications
Microfluidic Technologies for Miniaturized Analysis Systems by Steffen Hardt,Friedhelm Schönfeld Pdf
This book addresses Lab-on-a-Chip devices. It focuses on microfluidic technologies that have emerged in the past decade. Coverage presents a comprehensive listing of the most promising microfluidic technologies in the Lab-on-a-Chip field. It also details technologies that can be viewed as toolboxes needed to set up complex Lab-on-a-Chip systems.
Introduction to Machine Olfaction Devices by Najib Altawell Pdf
Introduction to Machine Olfaction Devices discusses the various aspects of a MOD device, from historical approaches to state-of-the-art technologies. This book also covers the mechanism in dealing and detecting gases, odor, and aroma. Problems and solutions relevant to present day design have been outlined as well as a step-by-step guide to Machine Olfaction Device (MOD) design. Sensors and gas systems, along with polymers and certain manufacturing processes, have been discussed, together with other relevant materials for the MOD process and functions including comparison and validations, data processing, data analysis, MOD new design, micro systems, and monitoring systems. Aimed at developing a novel and improved MOD with more efficient on-board data processing capability for monitoring applications, this book will help you to design an MOD with a faster stabilizing base line; a quicker sample result display; an ability to use ambient air; a low power consumption; and the ability to deal with different varieties of organic/inorganic samples. With a focus on the most important and relevant aspects of designing MODs which currently require a solution, topics covered include MOD and market issues, cost, technical issues, and MOD applications. With a huge range of potential applications, this book will be of special interest to those working (or studying) in this field at every level, from Biomedical, Energy, or Electrical Engineers, to Computer or Food Scientists. Introduction to Machine Olfaction Devices discusses the various aspects of a MOD device, from historical approaches to state-of-the-art technologies. This book also covers the mechanism in dealing and detecting gases, odor, and aroma. Problems and solutions relevant to present day design have been outlined as well as a step-by-step guide to Machine Olfaction Device (MOD) design. Sensors and gas systems, along with polymers and certain manufacturing processes, have been discussed, together with other relevant materials for the MOD process and functions including comparison and validations, data processing, data analysis, MOD new design, micro systems, and monitoring systems. Aimed at developing a novel and improved MOD with more efficient on-board data processing capability for monitoring applications, this book will help you to design an MOD with a faster stabilizing base line; a quicker sample result display; an ability to use ambient air; a low power consumption; and the ability to deal with different varieties of organic/inorganic samples. With a focus on the most important and relevant aspects of designing MODs which currently require a solution, topics covered include MOD and market issues, cost, technical issues, and MOD applications. With a huge range of potential applications, this book will be of special interest to those working (or studying) in this field at every level, from Biomedical, Energy, or Electrical Engineers, to Computer or Food Scientists. Focuses on the most important and relevant aspects of designing machine olfaction devices (MOD) which currently require a solution Topics covered include: MOD and market issues; MOD and cost; MOD and technical issues; MOD applications
Acoustic Wave and Electromechanical Resonators by Humberto Campanella Pdf
This groundbreaking book provides you with a comprehensive understanding of FBAR (thin-film bulk acoustic wave resonator), MEMS (microelectomechanical system), and NEMS (nanoelectromechanical system) resonators. For the first time anywhere, you find extensive coverage of these devices at both the technology and application levels. This practical reference offers you guidance in design, fabrication, and characterization of FBARs, MEMS and NEBS. It discusses the integration of these devices with standard CMOS (complementary-metal-oxide-semiconductor) technologies, and their application to sensing and RF systems. Moreover, this one-stop resource looks at the main characteristics, differences, and limitations of FBAR, MEMS, and NEMS devices, helping you to choose the right approaches for your projects. Over 280 illustrations and more than 130 equations support key topics throughout the book.
16th European Symposium on Computer Aided Process Engineering and 9th International Symposium on Process Systems Engineering by Wolfgang Marquardt,Costas Pantelides Pdf
This proceedings book contains the papers presented at the joint conference event of the 9th Symposium on Process Systems Engineering (PSE'2006) and the 16th European Symposium on Computer Aided Process Engineering (ESCAPE-16), held in Garmisch-Partenkirchen, Germany, from July 9 – July 13, 2006. The symposium follows the first joint event PSE’97 / ESCAPE-7 in Trondheim, Norway (1997). The last two venues of the ESCAPE symposia were Barcelona, Spain (2005) and Lisbon, Portugal (2004) and the most recent PSE symposia were held in Kunming, China (2003) and Keystone, Colorado, USA (2000). The purpose of both series is to bring together the international community of researchers engineers who are interested in computing-based methods in process engineering. The main objective of the symposium is to review and present the latest developments and current state in Process Systems Engineering and Computer Aided Process Engineering. The focus of PSE’2006 / ESCAPE-16 has been on Modelling and Numerical Methods, Product and Process Design, Operations and Control, Biological Systems, Infrastructure Systems, and Business decision support. * reviews and presents the latest developments and current state of Process Systems Engineering and Computer Aided Process Engineering * contains papers presented at a joint conference event * bringing together an international community of researchers and engineers interested in computing-based methods in Process Engineering
Microsystems for Pharmatechnology by Andreas Dietzel Pdf
This book provides a comprehensive, state-of-the-art review of microfluidic approaches and applications in pharmatechnology. It is appropriate for students with an interdisciplinary interest in both the pharmaceutical and engineering fields, as well as process developers and scientists in the pharmaceutical industry. The authors cover new and advanced technologies for screening, production by micro reaction technology and micro bioreactors, small-scale processing of drug formulations, and drug delivery that will meet the need for fast and effective screening methods for drugs in different formulations, as well as the production of drugs in very small volumes. Readers will find detailed chapters on the materials and techniques for fabrication of microfluidic devices, microbioreactors, microsystems for emulsification, on-chip fabrication of drug delivery systems, respiratory drug delivery and delivery through microneedles, organs-on-chip, and more.