Microsystems For Pharmatechnology

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Microsystems for Pharmatechnology

Author : Andreas Dietzel
Publisher : Springer
Page : 348 pages
File Size : 43,9 Mb
Release : 2016-01-22
Category : Technology & Engineering
ISBN : 9783319269207

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Microsystems for Pharmatechnology by Andreas Dietzel Pdf

This book provides a comprehensive, state-of-the-art review of microfluidic approaches and applications in pharmatechnology. It is appropriate for students with an interdisciplinary interest in both the pharmaceutical and engineering fields, as well as process developers and scientists in the pharmaceutical industry. The authors cover new and advanced technologies for screening, production by micro reaction technology and micro bioreactors, small-scale processing of drug formulations, and drug delivery that will meet the need for fast and effective screening methods for drugs in different formulations, as well as the production of drugs in very small volumes. Readers will find detailed chapters on the materials and techniques for fabrication of microfluidic devices, microbioreactors, microsystems for emulsification, on-chip fabrication of drug delivery systems, respiratory drug delivery and delivery through microneedles, organs-on-chip, and more.

Pharmaceutical Nanotechnology, 2 Volumes

Author : Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde
Publisher : John Wiley & Sons
Page : 804 pages
File Size : 40,5 Mb
Release : 2017-06-19
Category : Technology & Engineering
ISBN : 9783527340545

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Pharmaceutical Nanotechnology, 2 Volumes by Jean Cornier,Andrew Owen,Arno Kwade,Marcel Van de Voorde Pdf

With its focus on concrete methods and recent advances in applying nanotechnology to develop new drug therapies and medical diagnostics, this book provides an overall picture of the field, from the fundamentals of nanopharmacy with the characterisation and manufacturing methods to the role of nanoparticles and substances. Actual examples of utilization include drug development issues, translation to the clinic, market prospects, and industrial commercialization aspects. The applications described are taken from cancer treatment as well as other major therapeutic areas, such as infectious diseases and dermatology. An in-depth discussion on safety, regulatory, and societal aspects rounds off the book. Written by a top team of editors and authors composed of the leading experts in Europe and the USA who have pioneered the field of nanopharmacy!

Microfluidics in Biotechnology

Author : Janina Bahnemann,Alexander Grünberger
Publisher : Springer Nature
Page : 383 pages
File Size : 42,7 Mb
Release : 2022-07-28
Category : Science
ISBN : 9783031041884

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Microfluidics in Biotechnology by Janina Bahnemann,Alexander Grünberger Pdf

This new volume introduces the applications of microfluidic systems to facilitate biotechnological and biomedical processes. It provides an overview on cutting-edge technologies, summarizes traditional and modern fabrication methods and highlights recent advances regarding the application of lab-on-a-chip (LoC) systems for bioanalytical purposes. This book is ideal for research scientists and students interested at the cross-section between biotechnology, chemistry and chemical engineering.

Pharmaceutical Inhalation Aerosol Technology, Third Edition

Author : Anthony J. Hickey,Sandro R. da Rocha
Publisher : CRC Press
Page : 784 pages
File Size : 48,8 Mb
Release : 2019-03-26
Category : Medical
ISBN : 9780429619564

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Pharmaceutical Inhalation Aerosol Technology, Third Edition by Anthony J. Hickey,Sandro R. da Rocha Pdf

This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and clearance that are used as measures of effective dose delivery. Key Features: Provides a thoroughly revised and expanded reference with authoritative discussions on the physiologic,pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosols Emphasizes the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery Addresses the physics, chemistry and engineering principles while establishing disease relevance Expands the ‘technology’ focus of the original volumes to address the title more directly Offers an impressive breadth of coverage as well as an international flavour from outstanding editors and contributors

Characterization of Pharmaceutical Nano- and Microsystems

Author : Leena Peltonen
Publisher : John Wiley & Sons
Page : 410 pages
File Size : 44,9 Mb
Release : 2020-10-27
Category : Science
ISBN : 9781119414025

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Characterization of Pharmaceutical Nano- and Microsystems by Leena Peltonen Pdf

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Proceedings of 15th International Conference on Electromechanics and Robotics "Zavalishin's Readings"

Author : Andrey Ronzhin,Vladislav Shishlakov
Publisher : Springer Nature
Page : 553 pages
File Size : 42,7 Mb
Release : 2020-09-01
Category : Technology & Engineering
ISBN : 9789811555800

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Proceedings of 15th International Conference on Electromechanics and Robotics "Zavalishin's Readings" by Andrey Ronzhin,Vladislav Shishlakov Pdf

This book features selected papers presented at the 15th International Conference on Electromechanics and Robotics “Zavalishin's Readings” – ER(ZR) 2020, held in Ufa, Russia, on 15–18 April 2020. The contributions, written by professionals, researchers and students, cover topics in the field of automatic control systems, electromechanics, electric power engineering and electrical engineering, mechatronics, robotics, automation and vibration technologies. The Zavalishin's Readings conference was established as a tribute to the memory of Dmitry Aleksandrovich Zavalishin (1900–1968) – a Russian scientist, corresponding member of the USSR Academy of Sciences and founder of the school of valve energy converters based on electric machines and valve converters energy. The first conference was organized by the Institute of Innovative Technologies in Electromechanics and Robotics at the Saint Petersburg State University of Aerospace Instrumentation in 2006.

Microfluidics for Pharmaceutical Applications

Author : Helder A. Santos,Dongfei Liu,Hongbo Zhang
Publisher : William Andrew
Page : 495 pages
File Size : 42,8 Mb
Release : 2018-10-12
Category : Science
ISBN : 9780128126608

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Microfluidics for Pharmaceutical Applications by Helder A. Santos,Dongfei Liu,Hongbo Zhang Pdf

Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications. Presents detailed coverage on the fabrication of novel drug delivery systems with desired characteristics, such as uniform size, Janus particles, and particular or combined responsiveness Includes a variety of case studies that explain principles Focuses on commercialization, cost, safety, society and educational issues of microfluidic applications, showing how microfluidics is used in the real world

Biomedical Applications of Microfluidic Devices

Author : Michael R. Hamblin,Mahdi Karimi
Publisher : Academic Press
Page : 352 pages
File Size : 47,5 Mb
Release : 2020-11-12
Category : Technology & Engineering
ISBN : 9780128187920

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Biomedical Applications of Microfluidic Devices by Michael R. Hamblin,Mahdi Karimi Pdf

Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Inhaled Medicines

Author : Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey
Publisher : Academic Press
Page : 439 pages
File Size : 50,9 Mb
Release : 2021-01-20
Category : Business & Economics
ISBN : 9780128149751

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Inhaled Medicines by Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey Pdf

Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues

Functional Biomaterials

Author : Anuj Kumar,Durgalakshmi Dhinasekaran,Irina Savina,Sung Soo Han
Publisher : CRC Press
Page : 374 pages
File Size : 51,5 Mb
Release : 2023-09-22
Category : Technology & Engineering
ISBN : 9781000912098

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Functional Biomaterials by Anuj Kumar,Durgalakshmi Dhinasekaran,Irina Savina,Sung Soo Han Pdf

With the emergence of additive manufacturing, mass customization of biomaterials for complex tissue regeneration and targeted drug delivery applications is possible. This book emphasizes the fundamental concepts of biomaterials science, their structure–property relationships and processing methods, and biological responses in biomedical engineering. It focuses on recent advancements in biomedical applications, such as tissue engineering, wound healing, drug delivery, cancer treatments, bioimaging, and theranostics. This book: Discusses design chemistry, modification, and processing of biomaterials Describes the efficacy of biomaterials at various scales for biological response and drug delivery Demonstrates technological advances from conventional to additive manufacturing Covers future of biofabrication and customized medical devices This volume serves as a go-to reference on functional biomaterials and is ideal for multi-disciplinary communities such as students and research professionals in materials science, biomedical engineering, healthcare, and medical fields.

The Mechanics of Inhaled Pharmaceutical Aerosols

Author : Warren H. Finlay
Publisher : Academic Press
Page : 302 pages
File Size : 48,5 Mb
Release : 2019-06-01
Category : Technology & Engineering
ISBN : 9780081027868

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The Mechanics of Inhaled Pharmaceutical Aerosols by Warren H. Finlay Pdf

The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies. Provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols Allows researchers in the field to gain an up-to-date, thorough understanding of the field from first principles Introduces the pharmaceutical aerosols field to the many engineers and scientists entering the area

Glassy Materials Based Microdevices

Author : Giancarlo C. Righini,Nicoletta Righini
Publisher : MDPI
Page : 284 pages
File Size : 45,8 Mb
Release : 2019-02-28
Category : Technology & Engineering
ISBN : 9783038976189

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Glassy Materials Based Microdevices by Giancarlo C. Righini,Nicoletta Righini Pdf

Microtechnology has changed our world since the last century, when silicon microelectronics revolutionized sensor, control and communication areas, with applications extending from domotics to automotive, and from security to biomedicine. The present century, however, is also seeing an accelerating pace of innovation in glassy materials; as an example, glass-ceramics, which successfully combine the properties of an amorphous matrix with those of micro- or nano-crystals, offer a very high flexibility of design to chemists, physicists and engineers, who can conceive and implement advanced microdevices. In a very similar way, the synthesis of glassy polymers in a very wide range of chemical structures offers unprecedented potential of applications. The contemporary availability of microfabrication technologies, such as direct laser writing or 3D printing, which add to the most common processes (deposition, lithography and etching), facilitates the development of novel or advanced microdevices based on glassy materials. Biochemical and biomedical sensors, especially with the lab-on-a-chip target, are one of the most evident proofs of the success of this material platform. Other applications have also emerged in environment, food, and chemical industries. The present Special Issue of Micromachines aims at reviewing the current state-of-the-art and presenting perspectives of further development. Contributions related to the technologies, glassy materials, design and fabrication processes, characterization, and, eventually, applications are welcome.

Proceedings of 5th International Conference on Advanced Manufacturing Engineering and Technologies

Author : Vidosav Majstorovic,Zivana Jakovljevic
Publisher : Springer
Page : 475 pages
File Size : 50,7 Mb
Release : 2017-04-22
Category : Technology & Engineering
ISBN : 9783319564302

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Proceedings of 5th International Conference on Advanced Manufacturing Engineering and Technologies by Vidosav Majstorovic,Zivana Jakovljevic Pdf

This book presents the proceedings from the 5th NEWTECH conference (Belgrade, Serbia, 5–9 June 2017), the latest in a series of high-level conferences that bring together experts from academia and industry in order to exchange knowledge, ideas, experiences, research results, and information in the field of manufacturing. The range of topics addressed is wide, including, for example, machine tool research and in-machine measurements, progress in CAD/CAM technologies, rapid prototyping and reverse engineering, nanomanufacturing, advanced material processing, functional and protective surfaces, and cyber-physical and reconfigurable manufacturing systems. The book will benefit readers by providing updates on key issues and recent progress in manufacturing engineering and technologies and will aid the transfer of valuable knowledge to the next generation of academics and practitioners. It will appeal to all who work or conduct research in this rapidly evolving field.

Case Studies in Micromechatronics

Author : Stephanus Büttgenbach,Iordania Constantinou,Andreas Dietzel,Monika Leester-Schädel
Publisher : Springer Nature
Page : 302 pages
File Size : 49,5 Mb
Release : 2020-05-15
Category : Technology & Engineering
ISBN : 9783662613207

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Case Studies in Micromechatronics by Stephanus Büttgenbach,Iordania Constantinou,Andreas Dietzel,Monika Leester-Schädel Pdf

The book “Case Studies in Micromechatronics – From Systems to Process” offers prominent sample applications of micromechatronic systems and the enabling fabrication technologies. The chosen examples represent five main fields of application: consumer electronics (pressure sensor), mobility and navigation (acceleration sensor), handling technology and automation (micro gripper), laboratory diagnostics (point of care system), and biomedical technology (smart skin). These five sample systems are made from different materials requiring a large variety of modern fabrication methods and design rules, which are explained in detail. As a result, an inverted introduction “from prominent applications to base technologies” is provided. Examples of applications are selected to offer a broad overview of the development environment of micromechatronic systems including established as well as cutting-edge microfabrication technologies.

Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems

Author : Sabu Thomas,Mazaher Ahmadi,Tuan Anh Nguyen,Abbas Afkhami,Tayyebeh Madrakian
Publisher : Elsevier
Page : 440 pages
File Size : 47,7 Mb
Release : 2021-10-12
Category : Technology & Engineering
ISBN : 9780128237281

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Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems by Sabu Thomas,Mazaher Ahmadi,Tuan Anh Nguyen,Abbas Afkhami,Tayyebeh Madrakian Pdf

Micro- and Nanotechnology Enabled Applications for Portable Miniaturized Analytical Systems outlines the basic principles of miniaturized analytical devices, such as spectrometric, separation, imaging and electrochemical miniaturized instruments. Concepts such as smartphone-enabled miniaturized detection systems and micro/nanomachines are also reviewed. Subsequent chapters explore the emerging application of these mobile devices for miniaturized analysis in various fields, including medicine and biomedicine, environmental chemistry, food chemistry, and forensic chemistry. This is an important reference source for materials scientists and engineers wanting to understand how miniaturization techniques are being used to create a range of efficient, sustainable electronic and optical devices. Miniaturization describes the concept of manufacturing increasingly smaller mechanical, optical, and electronic products and devices. These smaller instruments can be used to produce micro- and nanoscale components required for analytical procedures. A variety of micro/nanoscale materials have been synthesized and used in analytical procedures, such as sensing materials, sorbents, adsorbents, catalysts, and reactors. The miniaturization of analytical instruments can be applied to the different steps of analytical procedures, such as sample preparation, analytical separation, and detection, reducing the total cost of manufacturing the instruments and the needed reagents and organic solvents. Outlines how miniaturization techniques can be used to create new optical and electronic micro- and nanodevices Explores major application areas, including biomedicine, environmental science and security Assesses the major challenges of using miniaturization techniques