Microtubule Dynamics

Author : Anne Straube
Publisher : Humana Press
Page : 319 pages
File Size : 45,6 Mb
Release : 2017-04-30
Category : Science
ISBN : 1493961853

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Microtubule Dynamics by Anne Straube Pdf

Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtubule interactions in vitro, techniques to investigate the ultrastructure of microtubules and associated proteins, assays to study microtubule nucleation, turnover, and force production in cells, as well as approaches to isolate novel microtubule-associated proteins and their interacting proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Definitive and practical, Microtubule Dynamics: Methods and Protocols provides the key protocols needed by novices and experts on how to perform a broad range of well-established and newly-emerging techniques in this vital field.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 53,8 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : John J. Correia,Leslie Wilson
Publisher : Academic Press
Page : 472 pages
File Size : 42,8 Mb
Release : 2013-08-20
Category : Science
ISBN : 9780124078888

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Microtubules, in vitro by John J. Correia,Leslie Wilson Pdf

There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research Combines classical approaches and modern technologies Presents easy-to-use protocols and thorough background information, compiled by leaders in the field

Author : Amanda J. Johnson
Publisher : Unknown
Page : 94 pages
File Size : 44,7 Mb
Release : 1998
Category : Electronic
ISBN : STANFORD:36105025919882

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Microtubule Dynamics and Their Effectors by Amanda J. Johnson Pdf

Author : Jun Zhou
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 42,9 Mb
Release : 2007-08-23
Category : Medical
ISBN : 9781588296429

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Microtubule Protocols by Jun Zhou Pdf

Microtubules are essential components of the cytoskeleton, and play critical roles in a variety of cell processes, including cell shaping, intracellular tracking, cell division, and cell migration. Microtubule Protocols presents a comprehensive collection of essential and up-to-date methods for studying both the biology of microtubules and the mechanisms of action of microtubule-interacting drugs. The straightforward presentation of readily reproducible protocols is a hallmark of the Methods in Molecular MedicineTM series, and is evident in this volume. Methods presented range from the purification and characterization of microtubule proteins, analysis of post-translational modifications of tubulin, and determination of microtubule structure, to the visualization of microtubule and spindle behavior, measurement of microtubule dynamics, and examination of microtubule-mediated cellular processes. Both basic scientists and clinical researchers will benefit from this collection of state-of-the-art protocols for microtubule research.

Author : Jeremy S. Hyams,Clive W. Lloyd
Publisher : Wiley-Liss
Page : 466 pages
File Size : 44,6 Mb
Release : 1994
Category : Medical
ISBN : UOM:39015032916267

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Microtubules by Jeremy S. Hyams,Clive W. Lloyd Pdf

Microtubules reflects the enormous and significant advances in microtubule research of the past decade. It provides up-to-date information on the art of microtubule research, building on the success of Dr. Hyams's 1979 landmark text. A distinguished group of editors and contributors presents reviews dealing with three central topics: the biochemistry and assembly of the tubulin dimer; associated proteins and regulation of microtubule function; and microtubule organization and function in the cell.

Author : Helder Maiato
Publisher : Unknown
Page : 390 pages
File Size : 41,9 Mb
Release : 2020
Category : Cytology
ISBN : 1071602195

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Cytoskeleton Dynamics by Helder Maiato Pdf

This volume details comprehensive state-of-the-art methods on actin microfilaments and microtubules and how they work to achieve different cellular functions in different cellular contexts. Chapters guide readers through protein purification, in vitro reconstitution of several cytoskeleton properties, analyses of microtubule- and actin-based structures, functional dissection of post-translational modifications, and roles in several biological processes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cytoskeleton Dynamics: Methods and Protocols aims to provide a wide range of experimental approaches and be an invaluable resource for present and future generations of cytoskeleton researchers. .

Author : Jesus Avila
Publisher : CRC Press
Page : 276 pages
File Size : 47,6 Mb
Release : 2018-01-17
Category : Medical
ISBN : 9781351083096

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Microtubule Proteins by Jesus Avila Pdf

This work focuses on the structural and functional description of the microtubule proteins. The objective of the authors is to establish a relationship between the structure of microtubule proteins and the functions in which these polymers are involved. This book covers topics which have been treated only in a preliminary manner in previous works, such as microtubule dynamics and microtubule poisons. Microtubules display a variety of cellular roles and are vital for the separation and correct distribution of chromosomes during cell division. They also play an important role in morphogenesis, intracellular transport, secretion, and motility. Microtubule Proteins is a concise, easy-to-read text which is particularly of interest to cell biologists, chemists, neurochemists, and graduate students interested in cell biology.

Author : Anonim
Publisher : Academic Press
Page : 552 pages
File Size : 51,8 Mb
Release : 2010-09-24
Category : Science
ISBN : 0123813506

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Microtubules: in vivo by Anonim Pdf

Microtubules: in vivo includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton. The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation. Includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation

Author : Antonio Tito Fojo
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 44,9 Mb
Release : 2009-01-14
Category : Medical
ISBN : 9781597453363

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The Role of Microtubules in Cell Biology, Neurobiology, and Oncology by Antonio Tito Fojo Pdf

This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.

Author : Baoying Huang
Publisher : Unknown
Page : 298 pages
File Size : 40,6 Mb
Release : 2006
Category : Electronic
ISBN : CORNELL:31924105585016

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Functional Analysis of Microtubule Dynamics in Saccharomyces Cerevisiae by Baoying Huang Pdf

Author : Sharyn A. Endow,David M. Glover
Publisher : OUP Oxford
Page : 346 pages
File Size : 40,7 Mb
Release : 1998-10-01
Category : Science
ISBN : 9780191565779

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Dynamics of Cell Division by Sharyn A. Endow,David M. Glover Pdf

This volume focuses on the structural aspects of cell division - concentrating on both nuclear division (meiosis and mitosis) and cytoplasmic division (cytokinesis). Written as a companion volume to the earlier book in the series - Cell Cycle Control, this book provides an up-to-date account of developments in this exciting area of cell biology.

Author : Weidong Yang
Publisher : Springer
Page : 274 pages
File Size : 42,8 Mb
Release : 2018-07-27
Category : Science
ISBN : 9783319773094

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Nuclear-Cytoplasmic Transport by Weidong Yang Pdf

Dysfunction of nuclear-cytoplasmic transport systems has been associated with many human diseases. Thus, understanding of how functional this transport system maintains, or through dysfunction fails to maintain remains the core question in cell biology. In eukaryotic cells, the nuclear envelope (NE) separates the genetic transcription in the nucleus from the translational machinery in the cytoplasm. Thousands of nuclear pore complexes (NPCs) embedded on the NE selectively mediate the bidirectional trafficking of macromolecules such as RNAs and proteins between these two cellular compartments. In this book, the authors integrate recent progress on the structure of NPC and the mechanism of nuclear-cytoplasmic transport system in vitro and in vivo.

Author : Anonim
Publisher : ScholarlyEditions
Page : 80 pages
File Size : 43,5 Mb
Release : 2012-01-09
Category : Science
ISBN : 9781464936807

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Microtubule Proteins: Advances in Research and Application: 2011 Edition by Anonim Pdf

Microtubule Proteins: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Microtubule Proteins in a concise format. The editors have built Microtubule Proteins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Microtubule Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Microtubule Proteins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Jose C. Jimenez-Lopez
Publisher : BoD – Books on Demand
Page : 344 pages
File Size : 41,6 Mb
Release : 2017-05-17
Category : Science
ISBN : 9789535131694

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Cytoskeleton by Jose C. Jimenez-Lopez Pdf

The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.