Microtubules

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Jun Zhou
Publisher : Springer Science & Business Media
Page : 307 pages
File Size : 40,8 Mb
Release : 2007-08-23
Category : Medical
ISBN : 9781588296429

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Microtubule Protocols by Jun Zhou Pdf

Microtubules are essential components of the cytoskeleton, and play critical roles in a variety of cell processes, including cell shaping, intracellular tracking, cell division, and cell migration. Microtubule Protocols presents a comprehensive collection of essential and up-to-date methods for studying both the biology of microtubules and the mechanisms of action of microtubule-interacting drugs. The straightforward presentation of readily reproducible protocols is a hallmark of the Methods in Molecular MedicineTM series, and is evident in this volume. Methods presented range from the purification and characterization of microtubule proteins, analysis of post-translational modifications of tubulin, and determination of microtubule structure, to the visualization of microtubule and spindle behavior, measurement of microtubule dynamics, and examination of microtubule-mediated cellular processes. Both basic scientists and clinical researchers will benefit from this collection of state-of-the-art protocols for microtubule research.

Author : Antonio Tito Fojo
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 53,7 Mb
Release : 2009-01-14
Category : Medical
ISBN : 9781597453363

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The Role of Microtubules in Cell Biology, Neurobiology, and Oncology by Antonio Tito Fojo Pdf

This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.

Author : Jens Lüders
Publisher : Springer
Page : 189 pages
File Size : 41,7 Mb
Release : 2016-04-08
Category : Science
ISBN : 9783709119037

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The Microtubule Cytoskeleton by Jens Lüders Pdf

This book provides an overview on the organization and function of the microtubule cytoskeleton, which is essential to many cellular processes and profoundly linked to a range of human diseases. Covering basic concepts as well as molecular details, the book discusses how microtubules are nucleated and organized into ordered arrays, at different cell cycle stages and in distinct cell types. In addition, the book highlights how defects in the microtubule cytoskeleton are linked to diseases such as neurodevelopmental disorders. The book is intended for students, graduates and more senior researchers in cell and developmental biology as well as for medical doctors.

Author : Anne Straube
Publisher : Humana Press
Page : 319 pages
File Size : 40,9 Mb
Release : 2017-04-30
Category : Science
ISBN : 1493961853

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Microtubule Dynamics by Anne Straube Pdf

Microtubules are at the heart of cellular self-organization, and their dynamic nature allows them to explore the intracellular space and mediate the transport of cargoes from the nucleus to the outer edges of the cell and back. In Microtubule Dynamics: Methods and Protocols, experts in the field provide an up-to-date collection of methods and approaches that are used to investigate microtubule dynamics in vitro and in cells. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study microtubule dynamics and microtubule interactions in vitro, techniques to investigate the ultrastructure of microtubules and associated proteins, assays to study microtubule nucleation, turnover, and force production in cells, as well as approaches to isolate novel microtubule-associated proteins and their interacting proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Definitive and practical, Microtubule Dynamics: Methods and Protocols provides the key protocols needed by novices and experts on how to perform a broad range of well-established and newly-emerging techniques in this vital field.

Author : Jesus Avila
Publisher : CRC Press
Page : 276 pages
File Size : 48,9 Mb
Release : 2018-01-17
Category : Medical
ISBN : 9781351083096

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Microtubule Proteins by Jesus Avila Pdf

This work focuses on the structural and functional description of the microtubule proteins. The objective of the authors is to establish a relationship between the structure of microtubule proteins and the functions in which these polymers are involved. This book covers topics which have been treated only in a preliminary manner in previous works, such as microtubule dynamics and microtubule poisons. Microtubules display a variety of cellular roles and are vital for the separation and correct distribution of chromosomes during cell division. They also play an important role in morphogenesis, intracellular transport, secretion, and motility. Microtubule Proteins is a concise, easy-to-read text which is particularly of interest to cell biologists, chemists, neurochemists, and graduate students interested in cell biology.

Author : Peter Nick
Publisher : Springer Science & Business Media
Page : 275 pages
File Size : 44,6 Mb
Release : 2008-04-10
Category : Science
ISBN : 9783540771784

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Plant Microtubules by Peter Nick Pdf

Since the publication of the first edition of Plant Microtubules in 2000, our understanding of microtubules and their manifold functions have advanced substantially. This revised edition highlights the morphogenetic potential of plant microtubules from three general viewpoints: Microtubules and Morphogenesis, Microtubules and Environment, Microtubules and Evolution. The book is an invaluable source of information for researchers as well as for graduate and advanced students.

Author : Anonim
Publisher : Academic Press
Page : 552 pages
File Size : 53,9 Mb
Release : 2010-09-24
Category : Science
ISBN : 0123813506

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Microtubules: in vivo by Anonim Pdf

Microtubules: in vivo includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton. The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation. Includes chapters by experts around the world on many aspects of microtubule imaging in living and fixed cells; assays to study microtubule function in a wide array of model organisms and cultured cells; high resolution approaches to study of the cytoskeleton The authors share their years of experience, outlining potential pitfalls and critical factors to consider in experimental design, experimental implementation and data interpretation

Author : Leslie Wilson,John J. Correia
Publisher : Academic Press
Page : 699 pages
File Size : 46,5 Mb
Release : 2010-07-03
Category : Science
ISBN : 0080888585

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Microtubules, in vitro by Leslie Wilson,John J. Correia Pdf

There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This volume (complemented by the forthcoming companion volume by Cassimeris and Tran) brings together current research and protocols in the field of microtoubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. * Chapters reflect both experimental procedures and new developments in the field of microtubule in vitro research. * Combines classical approaches and modern technologies * Presents easy-to-use protocols and thorough background information, compiled by leaders in the field

Author : Hikoichi Sakai,Hideo Mohri,Gary G. Borisy
Publisher : Academic Press
Page : 474 pages
File Size : 49,9 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483272207

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Biological Functions of Microtubules and Related Structures by Hikoichi Sakai,Hideo Mohri,Gary G. Borisy Pdf

Biological Functions of Microtubules and Related Structures is a compendium of papers presented at the 13th Oji International Seminar on The Biological Functions of Microtubules and Related Structures, held at Komaba Eminence in Tokyo in November, 1981. The papers discuss the molecular function of tubulin in various biological processes or events. The book is divided into six sections focusing on the various aspects of the functions and structures of microtubules -- the biochemistry and molecular biology of tubulin, including regulation of microtubule assembly; microtubule-dynein systems and other proteins in cell motility; microtubules and related proteins in mitosis; the interactions of cytoskeletal components; the cytoskeleton; and microtubules in membrane functions and transport. Biochemists, biologists, and molecular biologists will find the book interesting.

Author : John J. Correia,Leslie Wilson
Publisher : Academic Press
Page : 472 pages
File Size : 47,8 Mb
Release : 2013-08-20
Category : Science
ISBN : 9780124078888

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Microtubules, in vitro by John J. Correia,Leslie Wilson Pdf

There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research Combines classical approaches and modern technologies Presents easy-to-use protocols and thorough background information, compiled by leaders in the field

Author : Anonim
Publisher : ScholarlyEditions
Page : 255 pages
File Size : 49,8 Mb
Release : 2012-12-26
Category : Science
ISBN : 9781464996290

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Microtubule Proteins—Advances in Research and Application: 2012 Edition by Anonim Pdf

Microtubule Proteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Microtubule Proteins. The editors have built Microtubule Proteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Microtubule Proteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Microtubule Proteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Tim Raemaekers
Publisher : Leuven University Press
Page : 140 pages
File Size : 48,8 Mb
Release : 2003-09
Category : Science
ISBN : 9058673030

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NuSAP, a Novel Microtubule-Associated Protein Involved in Mitotic Spindle Organization by Tim Raemaekers Pdf

"Vitamin D and bone, Linking the fields of vitamin D and bone with those of the nucleus and mitotic spindle, Nucleus structure and dynamics, Organization of the nucleus, Microtubules and associated proteins, Mitosis and spindle assembly, Control and mechanism of spindle formation and dynamics, Materials and methods, NuSAP, and novel MAP involved in spindle organization, NuSAP expression in cultured osteoblasts: regulation during development and by 1,25-dihydroxyvitamin D3, Analysis of NuSAP gene expression at the tissue level and chromosomal localization of human and mouse NuSAP, Developmentally regulated expression of NuSAP in the rat testis and mouse embryo, Chromosomal localization of human and mouse Nusap, General discussion and perspectives."

Author : Eric Wong
Publisher : Axolotl Academic Publishing
Page : 283 pages
File Size : 50,7 Mb
Release : 2009
Category : Biology
ISBN : 9780985226114

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Cells: Molecules and Mechanisms by Eric Wong Pdf

"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.

Author : D.L. Gilbert,William J. Adelman,J.M. Arnold
Publisher : Springer Science & Business Media
Page : 560 pages
File Size : 54,9 Mb
Release : 1990-04-30
Category : Medical
ISBN : 0306435136

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Squid as Experimental Animals by D.L. Gilbert,William J. Adelman,J.M. Arnold Pdf

A greatly expanded revision of the Woods Hole standard of 1974, A guide to the laboratory use of the squid... The original eight lab manual chapters are supplemented by eight that serve as an introduction to squid biology. Subjects include natural history and husbandry, mating and embryology, neural membranes, cell biology, sensory systems, the squid's unique detoxifying enzyme. Physiology of the CNS, digestion and excretion are excluded. Annotation copyrighted by Book News, Inc., Portland, OR