Mitochondria And The Future Of Medicine

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Mitochondria and the Future of Medicine

Lee Know
Mitochondria and the Future of Medicine Book PDF

Author : Lee Know
Publisher : Chelsea Green Publishing
Page : 274 pages
File Size : 49,9 Mb
Release : 2018
Category : MEDICAL
ISBN : 9781603587679

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Mitochondria and the Future of Medicine by Lee Know Pdf

With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics. In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years. Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.

Power, Sex, Suicide

Nick Lane
Power Sex Suicide Book PDF

Author : Nick Lane
Publisher : OUP Oxford
Page : 370 pages
File Size : 44,7 Mb
Release : 2005-10-13
Category : Science
ISBN : 0191513016

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Power, Sex, Suicide by Nick Lane Pdf

Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford

Clinical Mitochondrial Medicine

Patrick F. Chinnery,Michael J. Keogh
Clinical Mitochondrial Medicine Book PDF

Author : Patrick F. Chinnery,Michael J. Keogh
Publisher : Cambridge University Press
Page : 229 pages
File Size : 50,9 Mb
Release : 2018-05-17
Category : Medical
ISBN : 9780521132985

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Clinical Mitochondrial Medicine by Patrick F. Chinnery,Michael J. Keogh Pdf

This interactive clinical textbook takes a system- and case-based approach in understanding mitochondrial disorders in clinical practice.

Mitochondria and the Heart

José Marín-García
Mitochondria and the Heart Book PDF

Author : José Marín-García
Publisher : Springer Science & Business Media
Page : 415 pages
File Size : 44,9 Mb
Release : 2005-05-05
Category : Medical
ISBN : 9780387255743

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Mitochondria and the Heart by José Marín-García Pdf

Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex network of cellular interactions, involving (1) generation and detoxification of reactive oxygen species, including superoxide anion, hy-drogen peroxide, and hydroxyl radical; (2) maintenance of the antioxidant glutathione in a reduced state and adequate level of mitochondrial matrix superoxide dismutase; (3) cytoplasmic calcium homeostasis, particularly under conditions of cellular calcium loading; (4) transport of metabolites between cytoplasm and matrix; (5) both programmed (apoptosis) and necrotic cell death; and (6) cell growth and development. It is therefore not surprising that this organelle has come to be the center stage in many current investigations of cardiovascular diseases, aging, and agi- related disease. Concomitant with these advances, an impressive effort is under- way for the development of new tools and methodologies to study mitochondrial structure and function, including powerful ways to visualize, monitor, and alter the organelle function to assess the genetic consequences of these perturbations.

Red Light Therapy: Miracle Medicine

Mark Sloan
Red Light Therapy Miracle Medicine Book PDF

Author : Mark Sloan
Publisher : Lulu.com
Page : 184 pages
File Size : 55,5 Mb
Release : 2020-02-10
Category : Electronic
ISBN : 9780994741899

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Red Light Therapy: Miracle Medicine by Mark Sloan Pdf

Supercharge your Health Without Negative Side Effects! Imagine a world without toxic drugs and endless lists of side effects. A world where a revolutionary new technology is used to accelerate healing of virtually all disease and conditions. Imagine red light therapy. Science writer Mark Sloan is the author of 3 bestselling books and is the creator of a popular blog delivering evidence-based health information which has helped tens of thousands of people get healthy. Red Light Therapy: Miracle Medicine is your ultimate guide to understanding red light therapy and how to use it to get the greatest possible results. If you like straightforward information, easy-to-follow techniques, and proven strategies, then you'll love Mark Sloan's next-level resource. Pick up your copy now by clicking the BUY NOW button at the top of this page!

Life - The Epic Story of Our Mitochondria

Lee Know ND
Life The Epic Story of Our Mitochondria Book PDF

Author : Lee Know ND
Publisher : FriesenPress
Page : 266 pages
File Size : 54,5 Mb
Release : 2014-08-19
Category : Bioenergetics
ISBN : 9781460251812

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Life - The Epic Story of Our Mitochondria by Lee Know ND Pdf

"Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion-mitochondria and bioenergetics. This legendary saga began over two billion years ago, when one bacterium entered another without being digested, ultimately creating the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that are responsible for this life-giving energy. Yet, current research has also revealed a dark side; many seemingly unconnected degenerative diseases have their roots in dysfunctional mitochondria. Modern research, however, has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. By reading this book, you are about to dive into this epic story, and learn how to add years to your life, and life to your years."--Back cover.

Mitochondrial Replacement Techniques

National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Sciences Policy,Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases
Mitochondrial Replacement Techniques Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Sciences Policy,Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases
Publisher : National Academies Press
Page : 201 pages
File Size : 46,8 Mb
Release : 2016-04-17
Category : Medical
ISBN : 9780309388702

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Mitochondrial Replacement Techniques by National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Health Sciences Policy,Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases Pdf

Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.

Mitochondrial Dysfunction

Lawrence H. Lash,Dean P. Jones
Mitochondrial Dysfunction Book PDF

Author : Lawrence H. Lash,Dean P. Jones
Publisher : Elsevier
Page : 528 pages
File Size : 52,6 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483218618

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Mitochondrial Dysfunction by Lawrence H. Lash,Dean P. Jones Pdf

Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.

Mitochondria Diet

Jeffrey Winzant
Mitochondria Diet Book PDF

Author : Jeffrey Winzant
Publisher : No Fluff Publishing
Page : 47 pages
File Size : 42,8 Mb
Release : 2023-01-26
Category : Health & Fitness
ISBN : PKEY:6610000435234

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Mitochondria Diet by Jeffrey Winzant Pdf

Did you know that mitochondrial health is an essential key to longevity and overall well-being? Mitochondria are often overlooked in the body’s complex cellular structure. They may not get as much attention as the brain or heart, but they are integral to overall health just like any other organ, and your health can be affected by the inner workings of these tiny organelles. For example, when your cells don’t use energy properly from food because they cannot metabolize glucose (a type of sugar), your mitochondria cellular structures stop functioning efficiently, resulting in insulin resistance as well—both upstream triggers for health problems like cardiovascular disease, diabetes, cancer, Alzheimer’s Disease, Parkinson’s Disease and much more. Fortunately, there are many steps that you can take to manage these mitochondrial dysfunctions through nutrition. That’s why we have outlined a 3-week meal plan designed with your mitochondria in mind. First things first, it’s a good idea to understand what mitochondria are and why they are vital for optimal health. Stay tuned for a deep dive into what they do, why you should care about them, and how you can take better care of them through nutrition. In this guide, you’ll discover: ● What are mitochondria ● Diet tips to help improve your mitochondria function ● Symptoms you can tell your cellular structures are not working properly ● A seven-day weekly plan ● Sample recipes to follow

Mitochondrial Metabolism

Jalal Pourahmad,Mohsen Rezaei
Mitochondrial Metabolism Book PDF

Author : Jalal Pourahmad,Mohsen Rezaei
Publisher : Academic Press
Page : 316 pages
File Size : 53,5 Mb
Release : 2021-07-28
Category : Science
ISBN : 9780128224090

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Mitochondrial Metabolism by Jalal Pourahmad,Mohsen Rezaei Pdf

Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more. This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders. Details the significant role of mitochondria in chronic diseases Presents new insights on the targeting of mitochondria for therapeutic purposes Includes updated results on mitotherapy and other mitochondria-oriented therapies

Mitochondria in Health and Disease

Ray Griffiths
Mitochondria in Health and Disease Book PDF

Author : Ray Griffiths
Publisher : Singing Dragon
Page : 338 pages
File Size : 46,7 Mb
Release : 2018-04-19
Category : Health & Fitness
ISBN : 9780857012883

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Mitochondria in Health and Disease by Ray Griffiths Pdf

What are the functions of mitochondria in the human body? Why might they stop working properly and what can happen as a result? How can personalized nutrition help to optimize mitochondrial function and prevent or address chronic conditions? This innovative book explores the incredibly complex biochemical roles of mitochondria in health and disease. When healthy, mitochondria provide us with ninety percent of our body's energy. When unhealthy, this can lead to many chronic and degenerative conditions including cancer and Alzheimer's disease. This guide helps practitioners to identify the mitochondrial dysfunction underlying a wide range of health complaints, and provides inspiration about relevant and emerging mitochondria-supportive dietary regimes and nutrients to explore within the model of personalized nutrition.

Medical and Health Genomics

Dhavendra Kumar,Stylianos Antonarakis
Medical and Health Genomics Book PDF

Author : Dhavendra Kumar,Stylianos Antonarakis
Publisher : Academic Press
Page : 358 pages
File Size : 46,8 Mb
Release : 2016-06-04
Category : Science
ISBN : 9780127999227

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Medical and Health Genomics by Dhavendra Kumar,Stylianos Antonarakis Pdf

Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog

Michael T. Chang
Mitochondrial Dysfunction A Functional Medicine Approach to Diagnosis and Treatment Get Rid of Fat Fatigue and Brain Fog Book PDF

Author : Michael T. Chang
Publisher : Unknown
Page : 194 pages
File Size : 53,5 Mb
Release : 2019-09-08
Category : Health & Fitness
ISBN : 1733397310

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Mitochondrial Dysfunction: A Functional Medicine Approach to Diagnosis and Treatment: Get Rid of Fat, Fatigue, and Brain Fog by Michael T. Chang Pdf

Are of sick and tired of being tired, overweight, brain fogged and depressed? You have tried everything and nothing makes a difference. The answer may lie deep inside your cells called the mitochondria, the energy factories that power the cell. By rebooting them in a proven treatment method, you can not only get rid of your symptoms but also prevent chronic degenerative diseases like cancer and Alzheimer's and even slow the aging process. Functional medicine can help you diagnose and treat mitochondrial dysfunction.Dr. Michael Chang, MD, CFMP, Board certified in Pathology and Laboratory Medicine, draws from his experience at Healed and Whole Clinic using a validated treatment approach to this condition. He has also personally experienced mitochondrial fatigue stemming from biomechanical leg pain from which he has now recovered by applying the same treatments as outlined in this book.

Your Mitochondria

Warren L. Cargal, L. Ac.
Your Mitochondria Book PDF

Author : Warren L. Cargal, L. Ac.
Publisher : Acupuncture Atlanta, Inc.
Page : 128 pages
File Size : 45,9 Mb
Release : 2019-07-17
Category : Health & Fitness
ISBN : 9781950282562

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Your Mitochondria by Warren L. Cargal, L. Ac. Pdf

"The book provides a well-researched and proven plan to increase your mitochondria's energy levels naturally to enjoy a healthy aging process." — Dr. Robyn Benson, DOM, Author, The Healthy Conscious Traveler and founder of The Self Care Revolution "This information will be invaluable for those who would like to use mitochondrial enhancement therapies to improve their general health and to extend their longevity." — Dr. Thomas N. Seyfried, Author, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer Want to live a longer, healthier life? Want to stave off age-related diseases? Want to look younger and maintain vitality? Then you must respect your mitochondria—your key to health and longevity. The powerhouses of the cell, mitochondria take in nutrients, break them down, and create energy-rich molecules that drive cellular processors in the body. Knowing how your mitochondria work is essential to your well-being. This book takes a deep dive into the relationship between mitochondrial health, overall health, and aging. Dr. Warren Cargal, a multi-book author, board-certified Acupuncturist, and an expert on Chinese medicine with over 20 years of experience will show you: - How unhealthy mitochondria can cause cardiovascular diseases, cardiometabolic syndrome, neurodegenerative diseases, arthritis, cancer, and aging effects on the skin, eyes, and muscles. - How to take control of and increase your energy reserves to make them efficient. - How to restore your mitochondria so you can combat increased body fat and reduced lean muscle mass, inefficient metabolism, increased low-grade inflammation, inadequate performance, accelerating aging, and, unfortunately for some, premature death. Your Mitochondria: Key to Health and Longevity is a must-read for anyone who wants to live an abundant and healthy life.

Mitochondria

Douglas C. Wallace,Richard Youle
Mitochondria Book PDF

Author : Douglas C. Wallace,Richard Youle
Publisher : Cold Spring Harbor Perspective
Page : 0 pages
File Size : 55,9 Mb
Release : 2013
Category : Science
ISBN : 193611335X

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Mitochondria by Douglas C. Wallace,Richard Youle Pdf

Mitochondria are intracellular organelles that power the cell by metabolizing glucose and other energy sources to generate ATP. They are also critical in programmed cell death, and dysfunction of mitochondrial components is implicated in numerous muscle and neurodegenerative disorders, including Parkinson's disease. This volume contains contributions examining the evolution and normal function of mitochondria in cells, as well as their roles in various pathologies.