Molecular Diagnostics In Dermatology And Dermatopathology

Author : Michael J. Murphy
Publisher : Springer Science & Business Media
Page : 478 pages
File Size : 53,7 Mb
Release : 2011-03-24
Category : Medical
ISBN : 9781607611714

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Molecular Diagnostics in Dermatology and Dermatopathology by Michael J. Murphy Pdf

Molecular Diagnostics in Dermatology and Dermatopathology presents the basics of molecular biology and molecular diagnostic methods most commonly used in the clinical laboratory, with an emphasis on the concepts and testing most relevant to dermatological diseases. Topics include the integration of newer diagnostic and prognostic techniques with ‘traditional’ histologic approaches, and discussions of regulatory, ethical, legal, economic issues and ‘newer’ technologies. This important diagnostic tool outlines the clinically relevant uses (i.e.; diagnostic, staging and/or prognostic) applications of these techniques in the field of dermatology. Molecular studies that investigate the pathogenesis of skin diseases will be excluded, unless they also have a direct diagnostic utility. The book will be of interest to practicing pathologists, dermatology and pathology residents, dermatologists, and dermatopathologists.

Author : Gregory A. Hosler,Kathleen M. Murphy
Publisher : Springer Science & Business
Page : 356 pages
File Size : 48,7 Mb
Release : 2014-04-30
Category : Medical
ISBN : 9783642540660

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Molecular Diagnostics for Dermatology by Gregory A. Hosler,Kathleen M. Murphy Pdf

Molecular diagnostics is an exploding field, and recent advances in our understanding of the molecular basis of disease have provided a platform for the development of new diagnostic tests as well as tests to predict tumor behavior and potential response to targeted therapy. This textbook provides a reference and practical guide to molecular diagnostics for dermatologists and dermatopathologists. It outlines our current understanding of the molecular underpinnings of dermatologic disease, describes the appropriate use of currently available molecular tests, and explains the interpretation of these tests in the context of diagnosis and management. Tests relating to various disorders are covered, including but not confined to melanoma, genodermatoses, and infectious disease. Pitfalls are highlighted and user-friendly algorithmic approaches, presented.

Author : Tammie Ferringer
Publisher : Elsevier Health Sciences
Page : 240 pages
File Size : 45,5 Mb
Release : 2012-10-30
Category : Medical
ISBN : 9781455747177

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Update in Dermatopathology, An Issue of Dermatologic Clinics - E-Book by Tammie Ferringer Pdf

This issue covers the scope of dermatopathology, with articles including Advances in Molecular Diagnostics, Melanoma Staging, IHC in Dermatopathology, and New Directions in the field. The issue is rounded out with coverage of Dermatopathology Eduction and Dermatopathology and the Law.

Author : Gregory A Hosler
Publisher : JP Medical Ltd
Page : 8 pages
File Size : 48,8 Mb
Release : 2016-12-15
Category : Medical
ISBN : 9781909836129

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Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E by Gregory A Hosler Pdf

The practice of dermatopathology has evolved from viewing predominantly haematoxylin and eosin (H&E)-stained sections through the microscope to include an array of more specialized tests. These are used as stand-alone tests or in addition to the H&E. Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is a practical guide to the most important of these new diagnostic techniques. Aside from a brief review of H&E in the Introduction, the focus of the book is on the wide range of more recent ancillary tests commonly used by clinicians, including sections on special stains, immunohistochemistry, immunofluorescence, electron microscopy and molecular testing. Each section describes why each of these tests is performed, how to use them and how to interpret the results they provide. Abundantly illustrated with colour photographs, diagrams and algorithms Diagnostic Dermatopathology: A Guide to Ancillary Tests Beyond the H&E is packed with practical guidance on commonly-faced diagnostic dilemmas, how the tests described can be used to resolve them and how to avoid pitfalls in the diagnostic process. The book is an essential resource for trainee and practicing dermatopathologists, dermatologists and pathologists seeking an accessible guide to the diagnostic methods which are increasingly important in dermatopathology and which go beyond the H&E. Key features Covers the full range of diagnostic tests in dermatopathology, aside from H&E, with a focus on practical clinical information such as how to run the test, when to use it and how to interpret the results Includes special stains, immunohistochemistry, immunofluorescence, electron microscopy, molecular testing and point of care tests including potassium hydroxide preparations, mineral oil preparations, and Tzanck smears Single author with hand-picked specialist contributors provide a consistent approach to the subject, replete with diagnostic tips and clinical advice based on extensive personal experience

Author : Klaus J. Busam
Publisher : Elsevier Health Sciences
Page : 720 pages
File Size : 42,6 Mb
Release : 2014-12-30
Category : Medical
ISBN : 9780323261951

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Dermatopathology E-Book by Klaus J. Busam Pdf

Part of the Foundations in Diagnostic Pathology Series, Dermatopathology is a comprehensive resource that compiles all of today’s most essential dermatopathology information into a compact, high-yield format. This medical reference book’s well-organized approach and full-color illustrations result in a user-friendly reference that helps the reader access the latest information on molecular diagnostic tests, ancillary tools, and dermatologic disorders. It's perfect for exam prep and clinical application! Explore a range of neoplastic and non-neoplastic disorders of the skin. Access well-rounded, comprehensive coverage and detailed discussions of metabolic, systemic, allergic, infectious, and inflammatory skin diseases and cutaneous neoplasms. Take advantage of enhanced diagnostic guidance with content that offers over 1,100 full-color, high-quality photographs that demonstrate the key features of pathologic lesions. Connect with a reader-centric format that employs a consistent, user-friendly organization throughout to present each pathologic entity's gross and microscopic features, prognostic and therapeutic considerations, ancillary studies, and differential diagnoses. Reference important information at a glance with an abundance of boxes and tables. Remain up to date with the latest diagnostically relevant molecular tests, such as cytogenetic tests and mutation analysis of melanocyctic tumors. Prepare for exams with additional entities relevant to examination and clinical settings. Stay abreast of the latest advances with brand-new chapters covering Ancillary Diagnostic Tools (such as special stains, immunofluorescence studies, immunohistochemistry, and molecular tests), Disorders of the Nail Apparatus, Genetic Disorders, and Drug Reactions. Easily comprehend complex topics with help from additional figures and a vastly improved image collection. Consult this title on your favorite e-reader.

Author : Klaus J. Busam
Publisher : Elsevier Health Sciences
Page : 701 pages
File Size : 40,9 Mb
Release : 2009-12-09
Category : Medical
ISBN : 9781455705979

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Dermatopathology E-Book by Klaus J. Busam Pdf

This new volume in the Foundations in Diagnostic Pathology Series packs all of today's most essential dermatopathology know-how into a compact, high-yield format! Its pragmatic, well-organized approach, abundant full-color illustrations, and at-a-glance tables make the information you need easy to access. Over 1,100 full-color photographs capture the appearance of a full range of skin lesions. • Covers both neoplastic and non-neoplastic disorders of the skin. • Provides detailed discussions of metabolic, systemic, allergic, infectious, and inflammatory skin diseases as well as cutaneous neoplasms giving you well-rounded, comprehensive coverage. • Offers over 1,100 full-color, high-quality photographs that demonstrate the key features of a wide variety of pathologic lesions offering enhanced diagnostic guidance. • Employs a consistent, user-friendly organization throughout to present each pathologic entity's gross and microscopic features, prognostic and therapeutic considerations, ancillary studies, and differential diagnoses. • Presents information in boxes and tables for at-a-glance reference.

Author : Franco Rongioletti,Bruce R. Smoller
Publisher : Springer Nature
Page : 513 pages
File Size : 49,9 Mb
Release : 2021-09-01
Category : Medical
ISBN : 9783030800277

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New and Emerging Entities in Dermatology and Dermatopathology by Franco Rongioletti,Bruce R. Smoller Pdf

In recent years new, obscure or poorly known dermatological disorders have been described and better defined, with emphasis on clinical, histopathological and etiopathogenetic features. Familiarity with these new, emerging or revisited clinical entities is fundamental, and recognizing them with their differential diagnosis has important implications in clinical practice for better patient management. This book offers an in-depth discussion of the clinical and pathologic features of newly described or less well-known and revisited cutaneous disorders. It provides clinical findings, as well as the histologic, immunologic, and molecular features of these diseases in addition to therapeutic notes. The first section of the book covers cutaneous diseases that lack any systemic implications, such as circumscribed palmoplantar hypokeratosis, necrotizing infundibular crystalline folliculitis, and dermal hyperneury, amongst others. The second section offers coverage on cutaneous diseases with systemic implications, such as AESOP-POEMS syndrome, lipoatrophic panniculitis of children, and obesity associated with lymphedematous mucinosis. Each chapter describes an entity, along with an atlas of clinical manifestations that will serve as a “bed-side” clinical reference, followed by a series of photomicrographs depicting the histologic changes. Chapters also offer recent updates on molecular tools helpful in attaining the diagnosis as well as therapeutic recommendations based upon the more recent acquisitions. New and Emerging Entities in Dermatology and Dermatopathology is a must-have reference for the practicing dermatopathologist, internists, general pathologist reviewing skin biopsies, general dermatologists, family practitioners and nurse practitioners, geneticists, immunologists and other health care providers that care for patients with skin conditions.

Author : Raymond R. Tubbs,Mark H. Stoler
Publisher : Elsevier Health Sciences
Page : 452 pages
File Size : 53,8 Mb
Release : 2008-09-22
Category : Medical
ISBN : 9781437719482

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Cell and Tissue Based Molecular Pathology E-Book by Raymond R. Tubbs,Mark H. Stoler Pdf

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

Author : James W Patterson
Publisher : Elsevier
Page : 1320 pages
File Size : 48,7 Mb
Release : 2020-02
Category : Medical
ISBN : 0702075825

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Weedon's Skin Pathology by James W Patterson Pdf

Encyclopedic and authoritative, Weedon's Skin Pathology has earned outstanding reviews and accolades from practicing and trainee dermatopathologists, general pathologists, and dermatologists worldwide. The 5th Edition continues the tradition of excellence, helping you accurately and efficiently sign out challenging skin cases in everyday practice, while also keeping you up to date with recent advances in the field. This single-authored text provides comprehensive coverage of the full spectrum of dermatopathological entities, both inflammatory and neoplastic, highlighted by more than 1,200 large-sized, high-quality illustrations. Helps you arrive at the most accurate diagnoses possible by demonstrating what is seen through the microscope and identifying the characteristic features of the lesion - for established disorders, unusual and rare disease entities, and incompletely defined entities. Includes updated and expanded information on molecular diagnostics, including FISH (fluorescence in situ hybridization) techniques, plus new developments in molecular biology and molecular techniques, targeted-personalized medicine, and immunohistochemistry. Brings you fully up to date with carefully reviewed and streamlined introductory and basic science information and information on new entities since the previous edition. Presents even more key information in quick-reference formats such as tables and boxes that organize diseases into groups, synthesize diagnostic criteria, and list differential diagnoses. Identifies both important articles and more rare and unusual reports with remarkably authoritative, comprehensive, current, and relevant reference lists (over 35,000) for each entity. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Springer Science & Business Media
Page : 567 pages
File Size : 41,5 Mb
Release : 2007-10-28
Category : Medical
ISBN : 9781592599288

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Molecular Diagnostics by William B. Coleman,Gregory J. Tsongalis Pdf

Accompanying CD-ROM contains ... "a companion eBook version of Molecular diagnostics : for the clinical laboratorian, Second edition ... for downloading and use in the reader's PC or PDA."--Page 4 of cover.

Author : W. Edward Highsmith, Jr.
Publisher : Springer Science & Business Media
Page : 260 pages
File Size : 45,9 Mb
Release : 2013-09-20
Category : Medical
ISBN : 9781461481270

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Molecular Diagnostics by W. Edward Highsmith, Jr. Pdf

Molecular Diagnostics: 12 Tests That Changed Everything focuses on specific laboratory tests and emphasizes how the availability of these tests has altered how clinicians treat their patients. Presented as a standard outline, each chapter focuses on a specific molecular test and provides background on the test and its clinical applications. Continuing with some discussion on how the test is done, interpreted, and used clinically, each chapter then concludes with a discussion of how that test has changed the way medicine is practiced with respect to the disease or condition in question. Authored by renowned experts in the field, Molecular Diagnostics: 12 Tests That Changed Everything is a valuable resource for pathologists, pathology residents, laboratory directors, development personnel, lab medicine fellows and those working in the broad area of oncology, infectious disease and genetics.

Author : Iris Schrijver
Publisher : Springer Science & Business Media
Page : 339 pages
File Size : 55,6 Mb
Release : 2011-09-09
Category : Medical
ISBN : 3642196772

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Diagnostic Molecular Pathology in Practice by Iris Schrijver Pdf

This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.

Author : James Willis Patterson
Publisher : Unknown
Page : 1272 pages
File Size : 49,8 Mb
Release : 2021
Category : Skin
ISBN : 0702075817

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Weedon's Skin Pathology by James Willis Patterson Pdf

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 846 pages
File Size : 49,5 Mb
Release : 2023-10-27
Category : Science
ISBN : 9780128229934

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Diagnostic Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease

Author : Anonim
Publisher : ScholarlyEditions
Page : 295 pages
File Size : 46,5 Mb
Release : 2013-05-01
Category : Medical
ISBN : 9781490110530

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Issues in Pathology, Diagnostics, and Disease: 2013 Edition by Anonim Pdf

Issues in Pathology, Diagnostics, and Disease: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Molecular Diagnostics. The editors have built Issues in Pathology, Diagnostics, and Disease: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Molecular Diagnostics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pathology, Diagnostics, and Disease: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.