Molecular Mechanisms Of Membrane Fusion

Author : Shinpei Ohki
Publisher : Springer Science & Business Media
Page : 583 pages
File Size : 44,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461316596

Get Book

Molecular Mechanisms of Membrane Fusion by Shinpei Ohki Pdf

Membrane fusion is an important molecular event which plays a pivotal role in many dynamic cellular processes, such as exocytosis, endocytosis, membrane biogenesis, fertilization, etc. While many reports on the physico-chem1cal process involved in membrane fusion have appeared in the literature and much information has accumulated, there has been no comprehensiv~ meeting of workers in the field. A recent symposium which took place at the Center for Tomorrow, State University of New York at Buffalo, New York, April 27-29, 1987, was the first meeting of its kind to specifically address the molecular mechanisms of membrane fusion. The Symposium consisted of oral, workshop and poster presentation sessions. The papers presented in the oral and workshop sessions are collected here and arranged approximately in the order presented at the Symposium. These papers are the most up-to-date and representative work at the for front of each aspect of membrane fusion. Although the readers may find some differences in interpretations regarding the molecular mechanisms of membrane fusion, there is an over all concensus that increased hydrophobicity and dehydration of the membrane surface are essential physico-chemical factors for membrane fusion to occur. We trust that these papers will contribute to your further understanding of the mechanisms of membrane fusion.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

Get Book

Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Anonim
Publisher : Academic Press
Page : 368 pages
File Size : 52,8 Mb
Release : 2011-07-25
Category : Science
ISBN : 9780123858924

Get Book

Membrane Fusion by Anonim Pdf

This volume of Current Topics in Membranes focuses on Membrane Fusion, beginning with fusion and fission of lipid bilayers, with reviews focused on hemifusion and dynamic remodeling of membranes catalyzed by dynamin. Other topics discussed include viral fusion, intracellular fusion, developmental cell fusion, and theoretical modeling.

Author : Jan Wilschut
Publisher : CRC Press
Page : 930 pages
File Size : 51,6 Mb
Release : 2019-11-14
Category : Medical
ISBN : 9781000723441

Get Book

Membrane Fusion by Jan Wilschut Pdf

This balanced volume provides a broad and coherent overview of recent progress in membrane fusion research—highlighting an interdisciplinary treatment of the subject from the fields of biophysics, biochemistry, cell biology, virology, and biotechnology—in a single volume., Featuring easy-access sections on the general properties of membranes and applications of membrane fusion techniques, this valuable sourcebook outlines membrane structure, lipid polymorphism, and intermembrane forces ... covers membrane fusion in model systems ... presents the fusogenic properties of enveloped viruses ... discusses the fusion and flow of intracellular membranes and cell-cell fusion occurring during fertilization and myogenesis ... offers applications of membrane fusion techniques in cell-biological research and biotechnology ... and more. Supplying a comprehensive view of this exciting topic, Membrane Fusion is a working resource for molecular, cell, and membrane biologists; biophysicists; biochemists; virologists; biotechnologists; microbiologists; immunologists; physiologists; and graduate and medical school students in biophysics, biochemistry, physiology, virology, cell biology, and biotechnology.

Author : D. James Morre,Kathryn E. Howell,John J.M. Bergeron
Publisher : Springer
Page : 418 pages
File Size : 47,7 Mb
Release : 2014-03-12
Category : Science
ISBN : 3662029294

Get Book

Molecular Mechanisms of Membrane Traffic by D. James Morre,Kathryn E. Howell,John J.M. Bergeron Pdf

The study of membrane traffic in reconstituted cell-free systems has generated an unprecedented amount of new information on the biochemistry, molecular biology and genetics of membrane-based molecular events that underly normal and abnormal cellular function. Many of the individual steps have now been isolated and dissected in simple systems that permit detailed molecular analyses of transport mechanisms and their regulation. Reconstituted events of intercompartment transport include inter-membrane recognition, and controlled membrane fusion-fission reactions. Among the many advances is the growi ng awareness of a remarkabl e evolutionary conservation of many of the components involved in the many steps of membrane traffic, this realization has accelerated greatly the pace of progress in the field. This book provides a collection of participant contributions from the 1992 Summer Research Conference, "Mol ecul ar Mechani sms of Membrane Traffi c, " jointly sponsored with NATO by the American Society of Cell Biology. The conference was held May 9-13, at the Airlie Conference Center in the Virginia countryside, near Warrenton. The conference was attended by 158 scientists. A unique feature was the high proportion of young scientists among the participants. Approximately 65% were students, postdoctoral fe 11 ows and young investigators. Each attendee contri buted to the conference with either a pl atform or poster presentation.

Author : Michael C. Chicka
Publisher : Unknown
Page : 282 pages
File Size : 41,5 Mb
Release : 2007
Category : Electronic
ISBN : WISC:89101331742

Get Book

Molecular Mechanisms by which Synaptotagmin Regulates Calcium-triggered Membrane Fusion by Michael C. Chicka Pdf

Author : Hitoshi Sawada,Naokazu Inoue,Megumi Iwano
Publisher : Springer
Page : 463 pages
File Size : 49,9 Mb
Release : 2014-02-07
Category : Science
ISBN : 9784431545897

Get Book

Sexual Reproduction in Animals and Plants by Hitoshi Sawada,Naokazu Inoue,Megumi Iwano Pdf

This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.

Author : Philip Yeagle
Publisher : Unknown
Page : 376 pages
File Size : 41,9 Mb
Release : 1993
Category : Medical
ISBN : UOM:39015026979164

Get Book

The Membranes of Cells by Philip Yeagle Pdf

In this new edition of The Membranes of Cells, all of the chapters have been updated, some have been completely rewritten, and a new chapter on receptors has been added. The book has been designed to provide both the student and researcher with a synthesis of information from a number of scientific disciplines to create a comprehensive view of the structure and function of the membranes of cells. The topics are treated in sufficient depth to provide an entry point to the more detailed literature needed by the researcher. Key Features * Introduces biologists to membrane structure and physical chemistry * Introduces biophysicists to biological membrane function * Provides a comprehensive view of cell membranes to students, either as a necessary background for other specialized disciplines or as an entry into the field of biological membrane research * Clarifies ambiguities in the field

Author : Romano Regazzi
Publisher : Springer Science & Business Media
Page : 186 pages
File Size : 50,6 Mb
Release : 2008-05-12
Category : Science
ISBN : 9780387399614

Get Book

Molecular Mechanisms of Exocytosis by Romano Regazzi Pdf

This book examines the role of key components in the exocytotic process, not only in neuronal and endocrine cells but in a variety of other relevant cell systems. So far, because of the large number of components involved, understanding of the molecular basis of exocytosis has remained the privilege of a relatively small group of specialists. The book collects up-to-date reviews from the forefront of this fascinating and rapidly evolving field.

Author : G. Benga,H. Baum,F.A. Kummerow
Publisher : Springer Science & Business Media
Page : 265 pages
File Size : 55,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461382744

Get Book

Membrane Processes by G. Benga,H. Baum,F.A. Kummerow Pdf

The burgeoning interest in biomembranes in recent years has been such that "membranology" is now virtuMtyasubject in its own right, cutting vertically, as it were, through the strata of conventional disciplines from mathematics and physics, through chemistry, to biology. The very scope of the topic is thus so daunting that it is tempting to treat it only at one stratum of this hierarchy, be it the biophysics of phospholipid bilayers or the biochemistry of interactions at the cell surface. Such an approach is entirely valid, particularly among specialists with common interests. However, this approach does present a distorted perspective to the newcomer to the field, and, more significantly, it fails to stimulate cross fertil ization of ideas among workers at the various disciplinary levels. For example, as in all areas of molecular biology, the clinicians are frequently unaware of the contributions to their problems that might be made by the application of more basic knowledge and techniques. Conversely, biochemists or biophysicists may be ignorant of the existing practical problems to which they might address their expertise.

Author : Corinne Nardin,Helmut Schlaad
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 44,7 Mb
Release : 2021-04-06
Category : Technology & Engineering
ISBN : 9783527810994

Get Book

Biological Soft Matter by Corinne Nardin,Helmut Schlaad Pdf

Biological Soft Matter Explore a comprehensive, one-stop reference on biological soft matter written and edited by leading voices in the field Biological Soft Matter: Fundamentals, Properties and Applications delivers a unique and indispensable compilation of up-to-date knowledge and material on biological soft matter. The book presents a thorough overview about biological soft matter, beginning with different substance classes, including proteins, nucleic acids, lipids, and polysaccharides. It goes on to describe a variety of superstructures and aggregated and how they are formed by self-assembly processes like protein folding or crystallization. The distinguished editors have included materials with a special emphasis on macromolecular assembly, including how it applies to lipid membranes, and proteins fibrillization. Biological Soft Matter is a crucial resource for anyone working in the field, compiling information about all important substance classes and their respective roles in forming superstructures. The book is ideal for beginners and experts alike and makes the perfect guide for chemists, physicists, and life scientists with an interest in the area. Readers will also benefit from the inclusion of: An introduction to DNA nano-engineering and DNA-driven nanoparticle assembly Explorations of polysaccharides and glycoproteins, engineered biopolymers, and engineered hydrogels Discussions of macromolecular assemblies, including liquid membranes and small molecule inhibitors for amyloid aggregation A treatment of inorganic nanomaterials as promoters and inhibitors of amyloid fibril formation An examination of a wide variety of natural and artificial polymers Perfect for materials scientists, biochemists, polymer chemists, and protein chemists, Biological Soft Matter: Fundamentals, Properties and Applications will also earn a place in the libraries of biophysicists and physical chemists seeking a one-stop reference summarizing the rapidly evolving topic of biological soft matter.

Author : Mark Marsh
Publisher : Springer Science & Business Media
Page : 259 pages
File Size : 48,9 Mb
Release : 2006-03-30
Category : Medical
ISBN : 9783540267645

Get Book

Membrane Trafficking in Viral Replication by Mark Marsh Pdf

Viruses are major pathogens in humans, and in the organisms with which we share this planet. The massive health and economic burden these agents impose has spurred a huge research effort to understand their most intimate details. One outcome of this effort has been the production, in many but certainly not all cases, of effective vaccines and therapies. - other consequence has been the realization that we can exploit viruses and put them to work on our behalf. Viruses are still seen to have the most - tential as vehicles for gene delivery and other therapeutic applications. However, their ability to exploit cellular functions to their own ends makes viruses not only highly effective pathogens but also exquisite experimental tools. Work with viruses underpins much of our current understanding of molecular cell biology and related fields. For membrane traffic in parti- lar, viruses have been crucial in providing insights into key cellular fu- tions and the molecular mechanisms underlying these events.

Author : R. Lipowsky,E. Sackmann
Publisher : Elsevier
Page : 537 pages
File Size : 52,9 Mb
Release : 1995-06-15
Category : Technology & Engineering
ISBN : 9780080541914

Get Book

Structure and Dynamics of Membranes by R. Lipowsky,E. Sackmann Pdf

The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.

Author : Zhao-Wen Wang
Publisher : Springer Science & Business Media
Page : 354 pages
File Size : 54,5 Mb
Release : 2010-11-16
Category : Medical
ISBN : 9781597454810

Get Book

Molecular Mechanisms of Neurotransmitter Release by Zhao-Wen Wang Pdf

Neurons in the nervous system organize into complex networks and their functions are precisely controlled. The most important means for neurons to communicate with each other is transmission through chemical synapses, where the release of neurotransmitters by the presynaptic nerve terminal of one neuron influences the function of a second neuron. Since the discovery of chemical neurotransmission by Otto Loewi in the 1920s, great progress has been made in our understanding of mol- ular mechanisms of neurotransmitter release. The last decade has seen an explosion of knowledge in this field. The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release. The contributors have made great efforts to write concisely but with sufficient background information, and to use figures/diagrams to present clearly key concepts or experiments. It is hoped that this book may serve as a learning tool for neuroscience students, a solid reference for neuroscientists, and a source of knowledge for people who have a general interest in neuroscience. I was fortunate to be able to gather contributions from a group of outstanding scientists. I thank them for their efforts. In particular, I want to thank Dr. Erik Jorgensen who offered valuable suggestions about the book in addition to contrib- ing an excellent chapter. I thank US National Science Foundation and National Institute of Health for their supports.

Author : Hugo J. Bellen
Publisher : Unknown
Page : 466 pages
File Size : 53,6 Mb
Release : 1999
Category : Cellular signal transduction
ISBN : UOM:39015048547338

Get Book

Neurotransmitter Release by Hugo J. Bellen Pdf

Understanding the mechanisms that underlie brain activity and function remains one of the major frontiers of biology. All the processes of how we co-ordinate our movements, sense our surroundings, react to stimuli and learn and retain information rely on complicated networks of neurons thatcommunicate with each other and their targets. This fast and accurate intercellular signalling most occurs at synapses, specialized processes of neurons that release chemical signals, called neurotransmitters. Neurotransmitters: Frontiers in Molecular Biology will provide the reader withextensive background information on neurotransmitter release. It takes a multidisciplinary approach, but does not assume previous knowledge having basic introductions to most topics. Topics however are covered in enough detail to be of interest to experts in the field. Throughout, emphasis is placedon the rationale by which proteins are assigned specific functions rather than just providing facts about function. The first chapter provides an introduction to the basic features and properties of the synapse and is followed by a chapter detailing several important techniques used to elucidatevarious aspects of release. Chapters 3 describes many of the biochemical approaches used to identify proteins involved in neurotransmitter release and then chapters 4 and 5 focus on more specific aspects of synaptic transmission: the proteins that transport neurotransmitters and the role ofphosphlipids in the process. The next five chapters concentrate on approaches to unravel the function of many proteins in vivo by using toxins, giant squid axons, C. elegans, Drosophila, and mice. The final chapter summarizes current knowledge on endocytosis and recycling. Knowledge of themolecular mechanisms underlying neurotransmitter release has expanded tremendously over the last 10 years. Many of the proteins involved have been isolated, but their roles have yet to be determined. These discoveries will be a major challenge and it is therefore the major aim of this book not onlyto provide information but also to generate excitement.