Molecular Pathology And The Dynamics Of Disease

Author : Maika G. Mitchell
Publisher : Academic Press
Page : 179 pages
File Size : 49,7 Mb
Release : 2018-04-16
Category : Law
ISBN : 9780128146118

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Molecular Pathology and the Dynamics of Disease by Maika G. Mitchell Pdf

Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. Assimilates theoretical knowledge with practical lab work Provides a needed clinical perspective, along with research and theory Highlights the impact of basic science on the practice of medicine

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 48,8 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 128 pages
File Size : 49,5 Mb
Release : 2018
Category : Electronic
ISBN : 012804070X

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Author : Debra G.B. Leonard
Publisher : Springer Science & Business Media
Page : 589 pages
File Size : 47,6 Mb
Release : 2007-11-25
Category : Medical
ISBN : 9780387332277

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Molecular Pathology in Clinical Practice by Debra G.B. Leonard Pdf

This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. Includes 189 illustrations, 45 in full-color. This textbook is a classic in the making and a must-have reference.

Author : Anthony Killeen
Publisher : Humana
Page : 0 pages
File Size : 49,6 Mb
Release : 2010-11-05
Category : Medical
ISBN : 1617373486

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Principles of Molecular Pathology by Anthony Killeen Pdf

Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. Using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. The growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.

Author : Debra G.B. Leonard
Publisher : Springer
Page : 200 pages
File Size : 44,6 Mb
Release : 2009-03-02
Category : Medical
ISBN : 0387981012

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Molecular Pathology in Clinical Practice: Infectious Diseases by Debra G.B. Leonard Pdf

Molecular Pathology in Clinical Practice: Infectious Diseases is an authoritative and comprehensive guide that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular infectious disease testing. The book integrates the latest advancements in the field with the basic principles and practical applications.

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 846 pages
File Size : 53,7 Mb
Release : 2023-10-27
Category : Science
ISBN : 9780128229934

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Diagnostic Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease

Author : William B. Coleman
Publisher : Academic Press
Page : 440 pages
File Size : 49,6 Mb
Release : 2010
Category : Medical
ISBN : 0123744180

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Essential Concepts in Molecular Pathology by William B. Coleman Pdf

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Student web site hosts "self-assessment" questions; Professor web site hosts all figures from book Each chapter ends with Key Summary Points and Suggested Readings

Author : Philip T. Cagle,Timothy Craig Allen
Publisher : Springer
Page : 190 pages
File Size : 46,9 Mb
Release : 2008-11-01
Category : Medical
ISBN : 0387896368

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Basic Concepts of Molecular Pathology by Philip T. Cagle,Timothy Craig Allen Pdf

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Author : Iris Schrijver
Publisher : Springer
Page : 339 pages
File Size : 52,6 Mb
Release : 2011-09-23
Category : Medical
ISBN : 3642196780

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Diagnostic Molecular Pathology in Practice by Iris Schrijver Pdf

This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in molecular genetic pathology (MGP): inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book will be ideal for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 49,5 Mb
Release : 1975
Category : Electronic
ISBN : OCLC:320401046

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Molecular Pathology by Anonim Pdf

Author : Jennifer L. Hunt
Publisher : Springer
Page : 282 pages
File Size : 54,9 Mb
Release : 2016-08-23
Category : Medical
ISBN : 148997914X

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Molecular Pathology of Endocrine Diseases by Jennifer L. Hunt Pdf

The past two decades have seen an ever accelerating growth in knowledge about molecular pathology of human diseases, which received a large boost with the sequencing of the human genome in 2003. Mole- lar diagnostics, molecular targeted therapy, and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types (general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners), clinical inves- gators, pathologists and medical laboratory directors, and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis, and treatment for their patients. Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice.

Author : Gregory J. Tsongalis
Publisher : Elsevier
Page : 240 pages
File Size : 43,7 Mb
Release : 2020-11-28
Category : Medical
ISBN : 0323722261

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Advances in Molecular Pathology by Gregory J. Tsongalis Pdf

This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection.

Author : B. Sneh,S. Jabaji-Hare,S.M. Neate,G. Dijst
Publisher : Springer Science & Business Media
Page : 561 pages
File Size : 44,9 Mb
Release : 2013-06-29
Category : Science
ISBN : 9789401729017

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Rhizoctonia Species: Taxonomy, Molecular Biology, Ecology, Pathology and Disease Control by B. Sneh,S. Jabaji-Hare,S.M. Neate,G. Dijst Pdf

Rhizoctonia Species: Taxonomy, Molecular Biology, Ecology, Pathology and Control, written by the world's most reputable experts in their respective fields of Rhizoctonia research, summarizes years of research in the various aspects of the ubiquitous complex group of soil-borne fungi belonging to the anamorph genus Rhizoctonia. Species of Rhizoctonia worldwide cause economically important diseases on most of the world's important plants such as cereals, potato, cotton, sugarbeet, vegetables, ornamentals and trees in nurseries. The subject reviews covered in the book include classic as well as modern approaches to Rhizoctonia research in: Taxonomy and Evolution, Genetics and Pathogenicity, Plant-Rhizoctonia Interactions, Ecology, Population and Disease Dynamics, Disease Occurrence and Management in Various Crops, Cultural Control, Biological Control, Germplasm for Resistance, Chemical and Integrated Control Strategies. It aims to be the standard reference source book on Rhizoctonia for the next decade or more, just as Parmeter et al. (1970) has been in the past. It will be an important publication for Rhizoctonia investigators, plant pathologists, students, extension specialists, crop producers and companies dealing with plant disease control.

Author : Yuri Dyakov,Vitaly Dzhavakhiya,Timo Korpela
Publisher : Elsevier
Page : 496 pages
File Size : 55,5 Mb
Release : 2007-01-09
Category : Science
ISBN : 0080469337

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Comprehensive and Molecular Phytopathology by Yuri Dyakov,Vitaly Dzhavakhiya,Timo Korpela Pdf

This book offers a collection of information on successive steps of molecular ‘dialogue’ between plants and pathogens. It additionally presents data that reflects intrinsic logic of plant-parasite interactions. New findings discussed include: host and non-host resistance, specific and nonspecific elicitors, elicitors and suppressors, and plant and animal immunity. This book enables the reader to understand how to promote or prevent disease development, and allows them to systematize their own ideas of plant-pathogen interactions. * Offers a more extensive scope of the problem as compared to other books in the market * Presents data to allow consideration of host-parasite relationships in dynamics and reveals interrelations between pathogenicity and resistance factors * Discusses beneficial plant-microbe interactions and practical aspects of molecular investigations of plant-parasite relationships * Compares historical study of common and specific features of plant immunity with animal immunity