Mouse Development

Author : Jacek Z. Kubiak
Publisher : Springer Science & Business Media
Page : 436 pages
File Size : 52,6 Mb
Release : 2012-08-23
Category : Science
ISBN : 9783642304064

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Mouse Development by Jacek Z. Kubiak Pdf

The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this achievement) and Matthew Kaufman. This book provides an overview of mouse development, spanning from oocytes before fertilization to the state-of-the-art description of embryonic and adult stem cells. The chapters, written by the leading specialists in the field, deal with the most recent discoveries in this extremely fast-developing area of research.

Author : Janet Rossant,Patrick P. L. Tam
Publisher : Gulf Professional Publishing
Page : 754 pages
File Size : 52,6 Mb
Release : 2002-03
Category : Medical
ISBN : 0125979517

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Mouse Development by Janet Rossant,Patrick P. L. Tam Pdf

This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production

Author : Andre M. Goffinet,Pasko Rakic
Publisher : Springer Science & Business Media
Page : 347 pages
File Size : 51,5 Mb
Release : 2012-08-10
Category : Science
ISBN : 9783540480020

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Mouse Brain Development by Andre M. Goffinet,Pasko Rakic Pdf

Our understanding of the molecular mechanisms involved in mammalian brain development remains limited. However, the last few years have wit nessed a quantum leap in our knowledge, due to technological improve ments, particularly in molecular genetics. Despite this progress, the available body of data remains mostly phenomenological and reveals very little about the grammar that organizes the molecular dictionary to articulate a pheno type. Nevertheless, the recent progress in genetics will allow us to contem plate, for the first time, the integration of observation into a coherent view of brain development. Clearly, this may be a major challenge for the next century, and arguably is the most important task of contemporary develop mental biology. The purpose of the present book is to provide an overview that syn thesizes up-to-date information on selected aspects of mouse brain devel opment. Given the format, it was not possible to cover all aspects of brain development, and many important subjects are missing. The selected themes are, to a certain extent, subjective and reflect the interests of the contributing authors. Examples of major themes that are not covered are peripheral nervous system development, including myelination, the development of the hippocampus and several other CNS structures, as well as the developmental function of some important morphoregulatory molecules.

Author : Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay
Publisher : Academic Press
Page : 343 pages
File Size : 47,6 Mb
Release : 2015-09-23
Category : Science
ISBN : 9780128009130

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Kaufman’s Atlas of Mouse Development Supplement by Richard Baldock,Jonathan Bard,Duncan Davidson,Gillian Morriss-Kay Pdf

Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. Provides high-resolution images for best visualization of key developmental processes and structures Offers in-depth anatomy and morphological views of organ systems Written descriptions convey developmental origins of the organ systems

Author : Matthew H. Kaufman,Jonathan B.L. Bard
Publisher : Academic Press
Page : 306 pages
File Size : 55,9 Mb
Release : 1999-03-10
Category : Science
ISBN : 9780080573373

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The Anatomical Basis of Mouse Development by Matthew H. Kaufman,Jonathan B.L. Bard Pdf

This book is an essential anatomical resource for developmental biologists who need to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. The book is a companion to Kaufman's The Atlas of Mouse Development, and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also provides extensive comparisons with human developmental anatomy, both normal and abnormal. The book has extensive reference indexes detailing developmental stage criteria. The Anatomical Basis of Mouse Development will be a key reference work for anyone who needs to understand developmental anatomy in normal and mutant mice. Complements Kaufman's The Atlas of Mouse Development Gives anatomical descriptions from oogenesis to birth, at a level of detail that goes beyond that found in most literature Provides detailed explanations for geneticists and molecular biologists with limited anatomical background to help them understand the emergence of all the major structures in the mouse embryo Contains comprehensive indexes detailing the appearance of over 1000 organs, tissues, and their components at different stages of mouse embryogenesis Includes comparisons with normal and abnormal human development Contains over 100 clear line diagrams showing mouse developmental anatomy as well as lineage relationships for the major organ systems

Author : Brigid Hogan,Frank Costantini,Elizabeth Lacy
Publisher : Cold Spring Harbor Laboratory Press
Page : 352 pages
File Size : 41,7 Mb
Release : 1986
Category : Nature
ISBN : UOM:39015012640598

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Manipulating the Mouse Embryo by Brigid Hogan,Frank Costantini,Elizabeth Lacy Pdf

Of mouse development -- Setting up a colony for the production of transgenic mice -- Recovery, culture, and transfer of embryos -- Introduction of new genetic information into the developing mouse embryo -- Iolation of pluripotential stem cell lines -- Techhniques for visualizing genes and gene products -- In vitro culture of eggs, embryos, and teratocarcinoma cels -- Chemicals, supplies, and solutions.

Author : Janet Rossant,Patrick T. Tam
Publisher : Gulf Professional Publishing
Page : 731 pages
File Size : 48,9 Mb
Release : 2002-03-21
Category : Science
ISBN : 9780080537030

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Mouse Development by Janet Rossant,Patrick T. Tam Pdf

This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels*Extensive coverage of a wide range of developmental mutations of the mouse*Excellent benchmark illustrations of brain, craniofacial, gut and heart development*In-depth experiment-based assessment of concepts in mammalian development*Focus on models of specific relevance to human development*Comprehensive reference to key literature and electronic databases related to mouse development*High-quality full-color production

Author : Matthew H. Kaufman
Publisher : Academic Press
Page : 536 pages
File Size : 52,8 Mb
Release : 1992-09
Category : Medical
ISBN : UOM:39015020863133

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The Atlas of Mouse Development by Matthew H. Kaufman Pdf

Not since the early 1970s has there been an attempt to describe and illustrate the anatomy of the developing mouse embryo. More than ever such material is needed by biologists as they begin to unravel the molecular mechanisms underlying development and differentiation. After more than ten years of painstaking work, Matt Kaufman has completed The Atlas of Mouse Development--the definitive account of mouse embryology and development. For all those researching or studying mammalian development, The Atlas of Mouse Development will be the standard reference work for many years to come. Provides a comprehensive sequential account of the development of the mouse from pre-implantation to term Contains clear and concise descriptions of the anatomical features relevant to each stage of development Large format for easy use Contains explanatory notes and legends, and more than 180 meticulously labeled plates, 1,300 photographs of individual histological sections, and 200 electron micrographs, illustrating: Intermittent serial histological sections through embryos throughout embryogenesis and organogenesis Differentiation of specific organs and organ systems, including the spinal cord, eyes, gonads, kidneys, lungs and skeletal system External appearance of intact embryos throughout development

Author : Matthew H. Kaufman,Jonathan B.L. Bard
Publisher : Gulf Professional Publishing
Page : 306 pages
File Size : 41,9 Mb
Release : 1999-03-03
Category : Medical
ISBN : 9780124020603

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The Anatomical Basis of Mouse Development by Matthew H. Kaufman,Jonathan B.L. Bard Pdf

The Anatomical Basis of Mouse Development by Kaufman and Bard is an essential anatomical resource for developmental biologists needing to know about any aspect of mouse developmental anatomy, as well as for geneticists using the mouse embryo as a model. This book is a companion to Kaufman's The Atlas of Mouse Development and details the developmental anatomy of the early embryo, the transitional tissues, and all the major organ systems. It also includes extensive reference indexes detailing developmental stage criteria, when tissues first appear, and the constituent tissues of embryos at each of the 26 Theiler stages, as well as tissue and author indexes and a glossary. Key features: * Gives anatomical descriptions from oogenesis to birth at a level of detail that often goes beyond that found in the literature. * Provides detailed explanations for geneticists and molecular biologists with limited anatomical background to help them understand the emergence of all the major structures in the mouse embryo. * Contains comprehensive indexes detailing the appearance of over 1000 organs, tissues and their components at different stages of mouse embryogenesis, together with the Theiler developmental stages (1-26) at which each first appears. * Includes comparisons with normal and abnormal human development * Has over 100 clear line diagrams showing mouse developmental anatomy as well as lineage relationships for the major organ systems. This book will be a key reference work for anyone who needs to understand developmental anatomy in normal and mutant mice.

Author : George Paxinos,Glenda Halliday,Charles Watson,Mustafa S. Kassem
Publisher : Academic Press
Page : 384 pages
File Size : 41,7 Mb
Release : 2020-03-21
Category : Science
ISBN : 9780128226469

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Atlas of the Developing Mouse Brain by George Paxinos,Glenda Halliday,Charles Watson,Mustafa S. Kassem Pdf

Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation. Contains 176 high-resolution color scans of Nissl-stained coronal sections of the brain and skull of the fetal (E17.5), day-of-birth (P0), and day-six postnatal mouse (P6) Includes diagrams that delineate all structures of the brain, as well as peripheral nerves, ganglia, muscles, bones, veins and arteries of the head Presents approximately 5000 corrections and updates from the first edition Includes color codes of the veins, arteries, nerves and ganglions of the skull in diagrams

Author : National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition
Publisher : National Academies Press
Page : 188 pages
File Size : 41,8 Mb
Release : 1995-02-01
Category : Science
ISBN : 9780309051262

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Nutrient Requirements of Laboratory Animals, by National Research Council,Board on Agriculture,Committee on Animal Nutrition,Subcommittee on Laboratory Animal Nutrition Pdf

In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.

Author : Andras Nagy
Publisher : Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press
Page : 784 pages
File Size : 47,8 Mb
Release : 2003
Category : Science
ISBN : UOM:39015056178109

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Manipulating the Mouse Embryo by Andras Nagy Pdf

Provides background information and detailed protocols for developing a mouse colony and using the animals in transgenic and gene-targeting experiments. The protocols list the animals, equipment, and reagents required and step-by-step procedures. Topics include in vitro culture of preimplantation embryos, surgical procedures, the production of chimeras, and the analysis of genome alterations. The third edition adds protocols for cloning mice, modifying embryonic stem cells, intracytoplasmic sperm injection, and cryopreservation of embryos.

Author : Brad Bolon
Publisher : CRC Press
Page : 446 pages
File Size : 51,9 Mb
Release : 2015-04-24
Category : Medical
ISBN : 9781420070095

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Pathology of the Developing Mouse by Brad Bolon Pdf

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology experimentation in mice but, more importantly, a "how to interpret" resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity. The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit: baseline anatomic and physiologic traits of developing mice principles of good experimental design and statistical analysis for mouse developmental pathology studies procedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques; methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids; options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., "lesions") during development; and well-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).

Author : Roberts Rugh
Publisher : Unknown
Page : 448 pages
File Size : 49,8 Mb
Release : 1968
Category : Embryology
ISBN : UOM:39015004379841

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The Mouse; Its Reproduction and Development by Roberts Rugh Pdf

Author : Charles Watson,George Paxinos,Luis Puelles
Publisher : Academic Press
Page : 815 pages
File Size : 48,7 Mb
Release : 2011-11-28
Category : Science
ISBN : 9780123694973

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The Mouse Nervous System by Charles Watson,George Paxinos,Luis Puelles Pdf

The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness