Nano Drug Delivery Strategies For The Treatment Of Cancers

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Nano Drug Delivery Strategies for the Treatment of Cancers

Author : Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Publisher : Academic Press
Page : 374 pages
File Size : 49,8 Mb
Release : 2020-09-03
Category : Science
ISBN : 9780128197943

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Nano Drug Delivery Strategies for the Treatment of Cancers by Awesh K. Yadav,Umesh Gupta,Rajeev Sharma Pdf

Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles

Advanced Drug Delivery Systems in the Management of Cancer

Author : Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone
Publisher : Elsevier
Page : 572 pages
File Size : 40,8 Mb
Release : 2021-06-24
Category : Business & Economics
ISBN : 9780323900799

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Advanced Drug Delivery Systems in the Management of Cancer by Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone Pdf

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Nanoparticle Drug Delivery Systems for Cancer Treatment

Author : Hala Gali-Muhtasib,Racha Chouaib
Publisher : CRC Press
Page : 342 pages
File Size : 53,7 Mb
Release : 2020-02-19
Category : Medical
ISBN : 9781000680874

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Nanoparticle Drug Delivery Systems for Cancer Treatment by Hala Gali-Muhtasib,Racha Chouaib Pdf

In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Author : Prashant Kesharwani
Publisher : Academic Press
Page : 340 pages
File Size : 47,7 Mb
Release : 2019-01-26
Category : Business & Economics
ISBN : 9780128163672

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Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by Prashant Kesharwani Pdf

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective

Author : Neeraj Mishra,Ashish Garg,Neeraj Upmanyu
Publisher : Bentham Science Publishers
Page : 421 pages
File Size : 53,6 Mb
Release : 2023-03-06
Category : Medical
ISBN : 9789815080513

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Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective by Neeraj Mishra,Ashish Garg,Neeraj Upmanyu Pdf

Nanotechnology has revolutionized cancer diagnosis and therapy through targeted drug delivery. Advances in protein engineering and materials science have led to the development of nanocarriers (NCs), which have helped overcome the challenges faced during conventional cancer treatment. These nanocarriers serve as an efficient transport module for drugs. Nano-drug delivery has emerged as a promising technology that results in early detection and better treatment of various cancers. The approved nanoparticles currently used in cancer treatment strategies include liposomes, dendrimers, polyplexes, solid lipid nano-carriers, etc. These nanocarriers can potentially provide a quick, safe, and cost-effective method in cancer therapy and management. This book presents thirteen chapters that cover cancer nanotherapeutics for various cancers. The reference covers lung, breast, cervical, ovarian, colon, prostate, and head and neck cancers. Each chapter reviews advanced data from existing and ongoing clinical research and major regulatory considerations. A list of scientific references for further reading supplements every chapter. Readers will be able to understand recent advances and challenges faced by researchers in cancer nanomedicine. This reference book will greatly benefit undergraduate and postgraduate students, oncologists, pharmacists, and researchers involved in nanomedicine and nano-drug delivery.

Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Author : Prashant Kesharwani,Kishore M. Paknikar,Virendra Gajbhiye
Publisher : Academic Press
Page : 434 pages
File Size : 53,9 Mb
Release : 2019-06-25
Category : Medical
ISBN : 9780128173312

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Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics by Prashant Kesharwani,Kishore M. Paknikar,Virendra Gajbhiye Pdf

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles

Nanoparticle-Based Drug Delivery in Cancer Treatment

Author : Loutfy H. Madkour
Publisher : CRC Press
Page : 558 pages
File Size : 51,6 Mb
Release : 2022-03-03
Category : Science
ISBN : 9781000532166

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Nanoparticle-Based Drug Delivery in Cancer Treatment by Loutfy H. Madkour Pdf

The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. Key Features: Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy Focuses on material platforms that establish NPs and both localized and controlled gene silencing Emphasizes the most promising systems for clinical application Surveys progress in nanoparticle-based nanomedicine in cancer treatment Describes the most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.

Nanoformulation Strategies for Cancer Treatment

Author : Sarwar Beg,Mahfoozur Rahman,Hani Choudhry,Eliana B. Souto,Farhan J. Ahmad
Publisher : Elsevier
Page : 402 pages
File Size : 53,8 Mb
Release : 2020-11-20
Category : Technology & Engineering
ISBN : 9780128210963

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Nanoformulation Strategies for Cancer Treatment by Sarwar Beg,Mahfoozur Rahman,Hani Choudhry,Eliana B. Souto,Farhan J. Ahmad Pdf

Nanoformulation Strategies for Cancer Treatment provides an up-to-date review on current developments and regulatory and clinical challenges in the field of nanopharmaceuticals and the effective treatment of diverse varieties of cancer. This important reference source is ideal for biomaterials scientists and pharmaceutical scientists working in the area of cancer diagnosis and therapy. Due to the high cost of traditional cancer treatment types, researchers have increasingly looked for new ways to augment the therapeutic performance of existing drug candidates. The use of nanotechnology-based approaches have gained significant momentum, thus leading to the launch of a series of new drug products. As nanopharmaceuticals improve the therapeutic performance of cancer therapy drugs, but also provide opportunities for site-specific drug targeting in tumors, this work is a welcomed resource on the topics discussed. Highlights the application of nanoformulations, including liposomes, nanoparticles and nanobiomaterials for targeted drug delivery to cancer cells Explores recent advances made using novel nanoformulations containing herbal drugs and biotechnology based therapeutic strategies for cancer treatment Assesses the regulatory hurdles that are necessary for the successful clinical translation of nanomedicines from the laboratory into the market

Cancer Targeted Drug Delivery

Author : You Han Bae,Randall J. Mrsny,Kinam Park
Publisher : Springer Science & Business Media
Page : 720 pages
File Size : 55,9 Mb
Release : 2013-08-31
Category : Medical
ISBN : 9781461478768

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Cancer Targeted Drug Delivery by You Han Bae,Randall J. Mrsny,Kinam Park Pdf

This book was conceived from a simple question as to why cancer is so difficult to treat. Ultimately we want to find ways to cure cancers, but that may be an elusive dream at least with the technologies we have now and expect to have in the near future. This leads the question of whether it is possible to improve current cancer treatment methods, especially from the perspective of enhancing targeted drug delivery to tumors. This volume is designed to provide information related to the difficulties in treating cancers through targeted drug delivery, our current understanding of cancer biology, and potential technologies that might be used to achieve enhanced drug delivery to tumors. An ideal drug delivery system for treating cancers would maximize the therapeutic efficacy with minimal side effects in clinical applications. The seemingly improved anticancer efficacy of the current nanoparticle-based formulations needs to be viewed from the context of very poor success rates for translation to human applications. The results of in vitro cell culture models and small animal in vivo experiments have not been extrapolated to clinical applications. Finding the reasons for the lack of successful translation is required if we are to discover approaches to substantially extend the survival time of cancer patients, and hopefully identify cures. Cancer Targeted Drug Delivery: Elusive Dream describes some answers of achieving the so far elusive dream of treating cancers like other chronic diseases with therapies that focus using improved drug delivery systems designed to better align with the unique biological and physiological properties of cancer.

Drug Delivery to Tumors

Author : Lesheng Teng,Zhaogang Yang,Chong Li
Publisher : Springer
Page : 0 pages
File Size : 52,8 Mb
Release : 2023-06-13
Category : Medical
ISBN : 981198929X

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Drug Delivery to Tumors by Lesheng Teng,Zhaogang Yang,Chong Li Pdf

This book summarizes emerging drug delivery strategies and new technologies for cancer treatment from the perspective of cancer pathology, including immunotherapy strategies, biomimetic drug delivery strategies, live cell drug delivery strategies, nanocrystal technology and 3D Printing technology, etc. With the development of related fields such as pharmaceutical science, materials science and nanomedicine, drug delivery systems have made significant progress in the treatment of cancer. With the in-depth study of different types of drug delivery systems, clinical transformation will be necessary. Some clinical trials have proved the obvious advantages of drug delivery vehicles in anti-cancer treatment. However, the characterization of nanomaterials, safety issues and production issues limit the application. Importantly, accurate in vitro and in vivo models are needed to predict the therapeutic effect of drug delivery systems in the clinic. The drug delivery system has been continuously innovated and improved in cancer treatment, and has broad application prospects.

Nanotheranostics for Cancer Applications

Author : Prakash Rai,Stephanie A. Morris
Publisher : Springer
Page : 484 pages
File Size : 48,6 Mb
Release : 2018-11-12
Category : Technology & Engineering
ISBN : 9783030017750

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Nanotheranostics for Cancer Applications by Prakash Rai,Stephanie A. Morris Pdf

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Nano-Oncologicals

Author : Maria José Alonso,Marcos Garcia-Fuentes
Publisher : Springer
Page : 473 pages
File Size : 48,7 Mb
Release : 2014-10-15
Category : Medical
ISBN : 9783319080840

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Nano-Oncologicals by Maria José Alonso,Marcos Garcia-Fuentes Pdf

This authoritative volume focuses on emerging technologies in cancer nano medicine, characterized by their multi-functionality and potential to address simultaneously diverse issues of clinical relevance in the treatment of cancer. The book consists of sixteen chapters divided into six sections: 1) Biological Barriers in Cancer; 2) Tumor Targeting; 3) Targeting the Immune System; 4) Gene Therapy; 5) Nano theranostics and 6) Translational Aspects of Nano-Oncologicals. The volume starts with an introduction describing the biological barriers associated with cancer therapy and highlighting ways to overcome such barriers through the use of nanotechnology. This is followed by an analysis of the two major targeting strategies currently under investigation in cancer therapy: namely, the targeting of cancer cells and the targeting of the immune system. In the first case, the book presents liposomal and polymer-based therapies, including photodynamic approaches. In the second case, it analyzes in detail the possibility of either improving the efficiency of the immune system toward preventing cancer progression (cancer immunomodulation) or generating responses against specific cancer antigens (cancer vaccines). Beyond these targeting options, Nano-Oncologicals: New Targeting and Delivery Approaches presents the most recent technological advances in the area of nucleic acid-based therapies, along with those in the area of theranostics, where the design of multifunctional nano carriers becomes vital. Following the study of the most promising nanotechnologies around the development of nano-oncologicals, the book ends with an overview of regulatory and toxicological issues, which are critical in their translational pathway, and the presentation of a nucleic acid-based therapy case-study. This book is an important resource for scientists interested in the design and development of anticancer nanotechnologies and also to those aiming to push their technology through clinical development.

Cancer And Nano Medicine

Author : Aliasghar Tabatabaei Mohammadi,Seyyed-Ghavam Shafagh,Ali Yousefi,Hossein Bagheri,Seyyede Sara Hashemian,Danyal Farajnia Rick,Mohammadhossein Mahdizadeh,Saina Karami,Tayebe Pouryousefi-koodehi,Shidoosh Homayoon,Mohammad mahdi Hanaei,Nasim Tavasolli,Baharzahra Nobahar
Publisher : Nobel TM
Page : 22 pages
File Size : 46,8 Mb
Release : 2022-04-09
Category : Medical
ISBN : 9798449498250

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Cancer And Nano Medicine by Aliasghar Tabatabaei Mohammadi,Seyyed-Ghavam Shafagh,Ali Yousefi,Hossein Bagheri,Seyyede Sara Hashemian,Danyal Farajnia Rick,Mohammadhossein Mahdizadeh,Saina Karami,Tayebe Pouryousefi-koodehi,Shidoosh Homayoon,Mohammad mahdi Hanaei,Nasim Tavasolli,Baharzahra Nobahar Pdf

Chapter1: Introduction Chapter2: Nano Medicine Chapter3: More sensitive cancer diagnosis and imaging Chapter4: Improvement of the drug Delivery Chapter5: Gold Nanoparticles Chapter6: Silver Nanoparticles Cancer Chapter7: Nano and RNA Chapter8: Nano-Enhanced Cancer Immunotherapy Chapter9: Nano and Micro Bubble

Drug Delivery with Targeted Nanoparticles

Author : Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Publisher : CRC Press
Page : 790 pages
File Size : 41,9 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9781000375268

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Drug Delivery with Targeted Nanoparticles by Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul Pdf

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors

Author : Prashant Kesharwani,Umesh Gupta
Publisher : Academic Press
Page : 478 pages
File Size : 48,5 Mb
Release : 2018-04-20
Category : Medical
ISBN : 9780128122495

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Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors by Prashant Kesharwani,Umesh Gupta Pdf

Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors