Drug Delivery With Targeted Nanoparticles

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Drug Delivery with Targeted Nanoparticles

Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Drug Delivery with Targeted Nanoparticles Book PDF

Author : Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Publisher : CRC Press
Page : 654 pages
File Size : 40,6 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9781000375305

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Drug Delivery with Targeted Nanoparticles by Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul Pdf

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Drug Delivery with Targeted Nanoparticles

Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Drug Delivery with Targeted Nanoparticles Book PDF

Author : Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul
Publisher : CRC Press
Page : 790 pages
File Size : 41,7 Mb
Release : 2021-11-30
Category : Medical
ISBN : 9781000375268

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Drug Delivery with Targeted Nanoparticles by Yılmaz Çapan,Adem Sahin,Hayrettin Tonbul Pdf

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Surface Modification of Nanoparticles for Targeted Drug Delivery

Yashwant V Pathak
Surface Modification of Nanoparticles for Targeted Drug Delivery Book PDF

Author : Yashwant V Pathak
Publisher : Springer
Page : 499 pages
File Size : 55,5 Mb
Release : 2019-03-11
Category : Medical
ISBN : 9783030061159

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Surface Modification of Nanoparticles for Targeted Drug Delivery by Yashwant V Pathak Pdf

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Multifunctional Nanoparticles for Drug Delivery Applications

Sonke Svenson,Robert K. Prud'homme
Multifunctional Nanoparticles for Drug Delivery Applications Book PDF

Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 51,6 Mb
Release : 2012-02-22
Category : Technology & Engineering
ISBN : 9781461423058

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Multifunctional Nanoparticles for Drug Delivery Applications by Sonke Svenson,Robert K. Prud'homme Pdf

This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. This book, unlike others covering nanoparticles used in medical applications, presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

Targeted Drug Delivery : Concepts and Design

Padma V. Devarajan,Sanyog Jain
Targeted Drug Delivery Concepts and Design Book PDF

Author : Padma V. Devarajan,Sanyog Jain
Publisher : Springer
Page : 788 pages
File Size : 44,6 Mb
Release : 2014-12-08
Category : Medical
ISBN : 9783319113555

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Targeted Drug Delivery : Concepts and Design by Padma V. Devarajan,Sanyog Jain Pdf

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer

Prashant Kesharwani
Nanotechnology Based Targeted Drug Delivery Systems for Lung Cancer Book PDF

Author : Prashant Kesharwani
Publisher : Academic Press
Page : 340 pages
File Size : 44,7 Mb
Release : 2019-01-26
Category : Business & Economics
ISBN : 9780128163672

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Nanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer by Prashant Kesharwani Pdf

Nanotechnology-based Targeted Drug Delivery Systems for Lung Cancer is an indispensable resource that will help pharmaceutical scientists and clinical researchers design and develop novel drug delivery systems and devices for the treatment of lung cancer. As recent breakthroughs in nanomedicine are now making it possible to deliver drugs, genes and therapeutic agents to localized areas of disease to maximize clinical benefit, while also limiting unwanted side effects, this book explores promising approaches for the diagnosis and treatment of lung cancer using cutting-edge nanomedical technologies. Topics discussed include polymeric nanoparticles, solid lipid nanoparticles, liposomes, dendrimers, micelles and nanoemulsions. Provides an overview of an array of nanotechnology-based drug delivery systems Examines the design, synthesis and application of different nanocarriers in drug and gene delivery Provides an in-depth understanding of the design of targeted nanotherapeutics and technologies and its implication in various site-specific cancers

Nanoparticles for Drug Delivery

K. S. Joshy,Sabu Thomas,Vijay Kumar Thakur
Nanoparticles for Drug Delivery Book PDF

Author : K. S. Joshy,Sabu Thomas,Vijay Kumar Thakur
Publisher : Springer Nature
Page : 214 pages
File Size : 52,7 Mb
Release : 2021-06-21
Category : Technology & Engineering
ISBN : 9789811621192

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Nanoparticles for Drug Delivery by K. S. Joshy,Sabu Thomas,Vijay Kumar Thakur Pdf

This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

Drug Delivery Approaches and Nanosystems, Volume 2

Raj K. Keservani,Anil K. Sharma,Rajesh K. Kesharwani
Drug Delivery Approaches and Nanosystems Volume 2 Book PDF

Author : Raj K. Keservani,Anil K. Sharma,Rajesh K. Kesharwani
Publisher : CRC Press
Page : 248 pages
File Size : 41,8 Mb
Release : 2017-11-15
Category : Medical
ISBN : 9781351846660

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Drug Delivery Approaches and Nanosystems, Volume 2 by Raj K. Keservani,Anil K. Sharma,Rajesh K. Kesharwani Pdf

This volume is a thorough presentation of the state-of-the-art research and developments in drug delivery systems using nanotechnology and its applications. The second of this two-volume set, it addresses the applications of nanotechnology or nano-sized materials in the medical field and the real-world challenges and complexities of current drug delivery methodologies and techniques. This volume includes 11 chapters that focus on the targeting facet of drug delivery systems. Targeting is a focused maneuver to achieve the specified goals, including achieving the desired result and reaching the specific location. Targeting has now been successfully achieved for several diseases/disorders; however, its role is noteworthy in cancer treatment where chemotherapy is a main course of approach. Nanotechnology-based products have great potential by virtue of their inherent features. This edited book provides a detailed application of nanotechnology in drug delivery systems in health care. The book discusses general principles of drug targeting, material of construction and technological concerns of nanoparticles, and different drug delivery systems and their preparation. Taken together, the informative chapters will provide researchers and scientists as well as faculty and students with valuable research on the effective use of new approaches in advanced drug delivery nanosystems. Volume 1 of the two-volume series is subtitled Novel Drug Carriers. The volumes are available separately or as a set.

Targeted Drug Delivery

Rachael W. Sirianni,Bahareh Behkam
Targeted Drug Delivery Book PDF

Author : Rachael W. Sirianni,Bahareh Behkam
Publisher : Humana Press
Page : 230 pages
File Size : 41,7 Mb
Release : 2018-07-27
Category : Medical
ISBN : 1493986597

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Targeted Drug Delivery by Rachael W. Sirianni,Bahareh Behkam Pdf

This volume looks at the latest techniques used to enable therapeutic molecules to be targeted for site-specific delivery. The chapters in this book discuss topics such as approaches to express biologically derived and synthetic nanocarriers; strategies to assist in nanocarrier targeting to specific cells and tissues; and methods for evaluating delivery and efficiency for new classes of agents. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Targeted Drug Delivery: Methods and Protocols is a valuable resource for anyone interested in understanding the diversity of methods used in this evolving field.

Frontiers of Engineering

National Academy of Engineering
Frontiers of Engineering Book PDF

Author : National Academy of Engineering
Publisher : National Academies Press
Page : 125 pages
File Size : 45,6 Mb
Release : 2019-02-28
Category : Technology & Engineering
ISBN : 9780309487504

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Frontiers of Engineering by National Academy of Engineering Pdf

This volume presents papers on the topics covered at the National Academy of Engineering's 2018 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2018 symposium was held September 5-7 and hosted by MIT Lincoln Laboratory in Lexington, Massachusetts. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work.

Nanomedicine in Drug Delivery

Arun Kumar,Heidi M. Mansour,Adam Friedman,Eric R. Blough
Nanomedicine in Drug Delivery Book PDF

Author : Arun Kumar,Heidi M. Mansour,Adam Friedman,Eric R. Blough
Publisher : CRC Press
Page : 465 pages
File Size : 53,7 Mb
Release : 2013-06-05
Category : Medical
ISBN : 9781466506169

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Nanomedicine in Drug Delivery by Arun Kumar,Heidi M. Mansour,Adam Friedman,Eric R. Blough Pdf

There is a clear need for innovative technologies to improve the delivery of therapeutic and diagnostic agents in the body. Recent breakthroughs in nanomedicine are now making it possible to deliver drugs and therapeutic proteins to local areas of disease or tumors to maximize clinical benefit while limiting unwanted side effects. Nanomedicine in Drug Delivery gives an overview of aspects of nanomedicine to help readers design and develop novel drug delivery systems and devices that build on nanoscale technologies. Featuring contributions by leading researchers from around the world, the book examines: The integration of nanoparticles with therapeutic agents The synthesis and characterization of nanoencapsulated drug particles Targeted pulmonary nanomedicine delivery using inhalation aerosols The use of biological systems—bacteria, cells, viruses, and virus-like particles—as carriers to deliver nanoparticles Nanodermatology and the role of nanotechnology in the diagnosis and treatment of skin disease Nanoparticles for the delivery of small molecules, such as for gene and vaccine delivery The use of nanotechnologies to modulate and modify wound healing Nanoparticles in bioimaging, including magnetic resonance, computed tomography, and molecular imaging Nanoparticles to enhance the efficiency of existing anticancer drugs The development of nanoparticle formulations Nanoparticles for ocular drug delivery Nanoparticle toxicity, including routes of exposure and mechanisms of toxicity The use of animal and cellular models in nanoparticles safety studies With its practical focus on the design, synthesis, and application of nanomedicine in drug delivery, this book is a valuable resource for clinical researchers and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner. It explores a wide range of promising approaches for the diagnosis and treatment of diseases using cutting-edge nanotechnologies.

Drug Delivery Using Nanomaterials

Yasser Shahzad,Syed A.A. Rizvi,Abid Mehmood Yousaf,Talib Hussain
Drug Delivery Using Nanomaterials Book PDF

Author : Yasser Shahzad,Syed A.A. Rizvi,Abid Mehmood Yousaf,Talib Hussain
Publisher : CRC Press
Page : 360 pages
File Size : 40,9 Mb
Release : 2022-01-18
Category : Medical
ISBN : 9781000529494

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Drug Delivery Using Nanomaterials by Yasser Shahzad,Syed A.A. Rizvi,Abid Mehmood Yousaf,Talib Hussain Pdf

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Silk-based Drug Delivery Systems

Elia Bari ,Sara Perteghella,Maria Luisa Torre
Silk based Drug Delivery Systems Book PDF

Author : Elia Bari ,Sara Perteghella,Maria Luisa Torre
Publisher : Royal Society of Chemistry
Page : 243 pages
File Size : 43,7 Mb
Release : 2020-10-07
Category : Science
ISBN : 9781788017725

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Silk-based Drug Delivery Systems by Elia Bari ,Sara Perteghella,Maria Luisa Torre Pdf

Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Multifunctional Nanoparticles for Drug Delivery Applications

Sonke Svenson,Robert K. Prud'homme
Multifunctional Nanoparticles for Drug Delivery Applications Book PDF

Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Page : 371 pages
File Size : 48,9 Mb
Release : 2012-02-22
Category : Medical
ISBN : 9781461423041

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Multifunctional Nanoparticles for Drug Delivery Applications by Sonke Svenson,Robert K. Prud'homme Pdf

This book presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles.

Nano Drug Delivery Strategies for the Treatment of Cancers

Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Nano Drug Delivery Strategies for the Treatment of Cancers Book PDF

Author : Awesh K. Yadav,Umesh Gupta,Rajeev Sharma
Publisher : Academic Press
Page : 374 pages
File Size : 48,8 Mb
Release : 2020-09-03
Category : Science
ISBN : 9780128197943

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Nano Drug Delivery Strategies for the Treatment of Cancers by Awesh K. Yadav,Umesh Gupta,Rajeev Sharma Pdf

Nano Drug Delivery Strategies for the Treatment of Cancers discusses several current and promising approaches for the diagnosis and treatment of cancer by using the most recent developments in nanomedical technologies. The book presents introductory information about the biology of different types of cancer in order to provide the reader with knowledge on their specificities. In addition, it discusses various novel drug delivery systems, detailing their functionalities, expected outcomes and future developments in the field, focusing on brain, mouth and throat, breast, lung, liver, pancreas, stomach, colon, bool, skin and prostate cancers. The book is a valuable source for cancer researchers, oncologists, pharmacologists and nanotechnologists who are interested in novel drug delivery systems and devices for treatment of various types of cancer that take advantage of recent advances in this exciting field. Discusses a wide range of promising approaches for the diagnosis and treatment of cancer using the latest advancement in cutting-edge nanomedical technologies Provides foundational information on different types of cancer and their biology to help the reader choose the best nano drug delivery system for patients Presents novel drug delivery systems based on nanoparticles, microparticles, liposomes, self-assembling Micelles and block copolymer micelles