Nanostructures For Novel Therapy

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Nanostructures for Novel Therapy

Author : Denisa Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 906 pages
File Size : 52,6 Mb
Release : 2017-02-25
Category : Technology & Engineering
ISBN : 9780323461481

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Nanostructures for Novel Therapy by Denisa Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Novel Therapy: Synthesis, Characterization and Applications focuses on the fabrication and characterization of therapeutic nanostructures, in particular, synthesis, design, and in vitro and in vivo therapeutic evaluation. The chapters provide a cogent overview of recent therapeutic applications of nanostructured materials that includes applications of nanostructured materials for wound healing in plastic surgery and stem cell therapy. The book explores the promise for more effective therapy through the use of nanostructured materials, while also assessing the challenges their use might pose from both an economic and medicinal point of view. This innovative look at how nanostructured materials are used in therapeutics will be of great benefit to researchers, providing a greater understanding of the different ways nanomaterials could improve medical treatment, along with a discussion of the obstacles that need to be overcome in order to guarantee widespread availability. Outlines how the characteristics of nanostructures made from different materials gives particular properties that can be successfully used in therapeutics Compares the properties of different nanostructures, allowing medicinal chemists and engineers to select which are most appropriate for their needs Highlights new uses of nanostructures within the therapeutic field, enabling the discovery of new, more effective drugs

Nanostructures for Antimicrobial Therapy

Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 722 pages
File Size : 44,9 Mb
Release : 2017-05-29
Category : Medical
ISBN : 9780323461511

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Nanostructures for Antimicrobial Therapy by Anton Ficai,Alexandru Mihai Grumezescu Pdf

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Nanostructures for Cancer Therapy

Author : Alexandru Mihai Grumezescu,Anton Ficai
Publisher : Elsevier
Page : 920 pages
File Size : 45,9 Mb
Release : 2017-04-11
Category : Technology & Engineering
ISBN : 9780323461504

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Nanostructures for Cancer Therapy by Alexandru Mihai Grumezescu,Anton Ficai Pdf

Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Design of Nanostructures for Theranostics Applications

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 692 pages
File Size : 45,6 Mb
Release : 2018-01-15
Category : Science
ISBN : 9780128136706

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Design of Nanostructures for Theranostics Applications by Alexandru Mihai Grumezescu Pdf

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

Nanostructures for the Engineering of Cells, Tissues and Organs

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 630 pages
File Size : 51,6 Mb
Release : 2018-02-14
Category : Science
ISBN : 9780128136669

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Nanostructures for the Engineering of Cells, Tissues and Organs by Alexandru Mihai Grumezescu Pdf

Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine

Nanostructures for Drug Delivery

Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 1024 pages
File Size : 51,6 Mb
Release : 2017-03-24
Category : Medical
ISBN : 9780323461498

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Nanostructures for Drug Delivery by Ecaterina Andronescu,Alexandru Mihai Grumezescu Pdf

Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial

Core-Shell Nanostructures for Drug Delivery and Theranostics

Author : Maria Focarete,Anna Tampieri
Publisher : Woodhead Publishing
Page : 466 pages
File Size : 44,6 Mb
Release : 2018-06-29
Category : Technology & Engineering
ISBN : 9780081021996

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Core-Shell Nanostructures for Drug Delivery and Theranostics by Maria Focarete,Anna Tampieri Pdf

Core-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry. Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics Explains the principles and essential concepts of nanotechnology for drug delivery systems

Nanostructures for Oral Medicine

Author : Ecaterina Andronescu,Alexandru Mihai Grumezescu
Publisher : Elsevier
Page : 1034 pages
File Size : 50,6 Mb
Release : 2017-04-11
Category : Medical
ISBN : 9780323477215

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Nanostructures for Oral Medicine by Ecaterina Andronescu,Alexandru Mihai Grumezescu Pdf

Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

Nanoparticles in Pharmacotherapy

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 632 pages
File Size : 48,7 Mb
Release : 2019-04-24
Category : Medical
ISBN : 9780128165041

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Nanoparticles in Pharmacotherapy by Alexandru Mihai Grumezescu Pdf

Nanoparticles in Pharmacotherapy explores the most recent findings on how nanoparticles are used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. This book is a valuable resource of recent scientific progress that includes the most cutting-edge applications of nanoparticles in pharmacotherapy. It is ideal for researchers, medical doctors and those in academia.

Biomedical Applications of Nanoparticles

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 530 pages
File Size : 42,6 Mb
Release : 2019-02-28
Category : Medical
ISBN : 9780128166307

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Biomedical Applications of Nanoparticles by Alexandru Mihai Grumezescu Pdf

Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view Presents the recent progress related to nanotherapeutics in the oral cavity Provides the recent progress in the field of biomedical nanoparticles

Biomedical Nanostructures

Author : Kenneth Gonsalves,Craig Halberstadt,Cato T. Laurencin,Lakshmi Nair
Publisher : John Wiley & Sons
Page : 543 pages
File Size : 41,9 Mb
Release : 2007-11-09
Category : Science
ISBN : 9780470185827

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Biomedical Nanostructures by Kenneth Gonsalves,Craig Halberstadt,Cato T. Laurencin,Lakshmi Nair Pdf

Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications.

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Author : Manju Rawat Singh,Deependra Singh,Jagat Kanwar,Nagendra Singh Chauhan
Publisher : Academic Press
Page : 657 pages
File Size : 43,9 Mb
Release : 2020-04-07
Category : Business & Economics
ISBN : 9780128199183

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Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents by Manju Rawat Singh,Deependra Singh,Jagat Kanwar,Nagendra Singh Chauhan Pdf

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications. Advances information on various bioactive based medications, their sources, clinical consequences and transport strategies Illustrates diverse transport systems for bioactives and derivatives, novel techniques for formulations, targeting strategies and fundamental qualities of developed bioactive carriers, and their safety concerns and standardization Discusses distinctive transport systems, stability, upgraded dissolvability, and enhanced bioavailability of bioactives

Nanotechnologies in Preventive and Regenerative Medicine

Author : Vuk Uskokovic
Publisher : Elsevier
Page : 616 pages
File Size : 47,6 Mb
Release : 2017-11-22
Category : Medical
ISBN : 9780323480642

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Nanotechnologies in Preventive and Regenerative Medicine by Vuk Uskokovic Pdf

Nanotechnologies in Preventative and Regenerative Medicine demonstrates how control at the nanoscale can help achieve earlier diagnoses and create more effective treatments. Chapters take a logical approach, arranging materials by their area of application. Biomaterials are, by convention, divided according to the area of their application, with each chapter outlining current challenges before discussing how nanotechnology and nanomaterials can help solve these challenges This applications-orientated book is a valuable resource for researchers in biomedical science who want to gain a greater understanding on how nanotechnology can help create more effective vaccines and treatments, and to nanomaterials researchers seeking to gain a greater understanding of how these materials are applied in medicine. Demonstrates how nanotechnology can help achieve more successful diagnoses at an earlier stage Explains how nanomaterials can be manipulated to create more effective drug treatments Offers suggestions on how the use of nanotechnology might have future applications to create even more effective treatments

Hybrid Nanostructures for Cancer Theranostics

Author : Raghvendra Ashok Bohara,Nanasaheb D. Thorat
Publisher : Elsevier
Page : 276 pages
File Size : 52,6 Mb
Release : 2018-11-19
Category : Science
ISBN : 9780128139073

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Hybrid Nanostructures for Cancer Theranostics by Raghvendra Ashok Bohara,Nanasaheb D. Thorat Pdf

Hybrid nanostructures are nanoparticles which incorporate two or more structures. These structures may represent organic or inorganic material, but they synergistically improve the application of the material for end users. Hybrid Nanostructures for Cancer Theranostics explores how hybrid nanostructures are used in cancer treatment. Focusing on the properties of hybrid nanostructures, the book demonstrates how their unique characteristics can be used to create more effective treatment techniques. In the second half of the book, the chapters examine how hybrid nanostructures are currently being used in practice, assessing the pros and cons of using different types of nanostructures for different treatments. This valuable resource will allow readers to understand the core and emerging concept of functionalization, bioconjugation, hyperthermia and phototherapy of nanoparticles which allows for the greater use of hybrid nanomaterials in cancer theranostics. Shows how the use of novel hybrid nanostructures can lead to more effective cancer treatments. Explores how hybrid nanostructures are used for different treatment types, including photo thermal therapy and drug delivery. Explains how the use of hybrid nanostructures can lead to more rapid cancer diagnosis.

Antimicrobial Nanoarchitectonics

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 574 pages
File Size : 52,7 Mb
Release : 2017-06-22
Category : Technology & Engineering
ISBN : 9780323527347

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Antimicrobial Nanoarchitectonics by Alexandru Mihai Grumezescu Pdf

Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems Includes case studies, showing how particular bionanomaterials have been used to cure infections Explains the central role that nanotechnology plays in modern antimicrobial therapy Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections