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Neurogenesis and Neural Plasticity by Catherine Belzung,Peter Wigmore Pdf
This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain. With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.
Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development
Author : National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development Publisher : National Academies Press Page : 610 pages File Size : 50,6 Mb Release : 2000-11-13 Category : Social Science ISBN : 9780309069885
From Neurons to Neighborhoods by National Research Council,Institute of Medicine,Board on Children, Youth, and Families,Committee on Integrating the Science of Early Childhood Development Pdf
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Sleep, Neuronal Plasticity and Brain Function by Peter Meerlo,Ruth M. Benca,Ted Abel Pdf
This book reviews current knowledge on the importance of sleep for brain function, from molecular mechanisms to behavioral output, with special emphasis on the question of how sleep and sleep loss ultimately affect cognition and mood. It provides an extensive overview of the latest insights in the role of sleep in regulating gene expression, synaptic plasticity and neurogenesis and how that in turn is linked to learning and memory processes. In addition, readers will learn about the potential clinical implications of insufficient sleep and discover how chronically restricted or disrupted sleep may contribute to age-related cognitive decline and the development of psychiatric disorders such as schizophrenia and depression. The book consists of 19 chapters, written by experts in basic sleep research and sleep medicine, which together cover a wide range of topics on the importance of sleep and consequences of sleep disruption. This book will be of interest to students, researchers and clinicians with a general interest in brain function or a specific interest in sleep.
The hippocampus is an important brain region, a true central hub for memory of various kinds and other processes. Neuropsychiatric disorders such as Alzheimer's disease, drug addiction, and schizophrenia are characterized by hippocampal alterations. The dentate gyrus of the hippocampus is a site exhibiting adult neurogenesis. This book covers the topic of the hippocampus from various perspectives. It discusses adult neurogenesis, effect of enriched environments on hippocampal plasticity, and long-term potentiation-associated gene expression. The book also addresses multiscale representations of complex environments and strategies in the hippocampus-dependent spatial tasks. Finally, insight into the hippocampus as a link between negative affect and relapse to psychostimulants is provided. The book collects evidence of various hippocampal functions in healthy and disordered brain.
The Rewiring Brain by Arjen van Ooyen,Markus Butz-Ostendorf Pdf
The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Reviews the current state of knowledge of structural plasticity in the adult brain Gives a comprehensive overview of computational studies on structural plasticity Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage
Toward a Theory of Neuroplasticity by Christopher A. Shaw,Jill McEachern Pdf
This book provides a broad survey of many of the major areas in neuroplasticity research by leading investigators in the field. The topics considered range across all levels of nervous system organization from the molecular to behavioral levels for species ranging from C. elegans to humans. In addition, the effects of development and neuropathological events are discussed. A final summary chapter synthesizes the data gathered in this volume in order to provide the basis for a general theory of neuroplasticity.
The Neuroscience of Adolescence by Adriana Galván Pdf
Written by an award-winning developmental neuroscientist, this is a comprehensive and cutting-edge account of the latest research on the adolescent brain.
Neuroplasticity: Simple Strategies to Better Manage Your Life (How to Boost Neurogenesis and Rewire Your Brain With Light) by Susan Smith Pdf
This book undertakes to accomplish three tasks in bringing the world of neuroplasticity to the everyday reader and to his or her idea of improving it in a way they see fit. It shows the reader that each person has the ability to alter and adjust the shape and resistance of his or her own mind. This is powerful information because when you alter the shape of the mind, you are essentially changing your destiny. Here is a preview of what you'll learn... • Boost neurogenesis • Improve brain circulation • Boost mitochondria • Reduce neuroinflammation • Promote the formation of new brain synapses • Improve sleep (and optimize cyrcadian rhythm) • Increase vitamin d without supplements • Become the best version of yourself • Much, muchmore! Everyone tries to get rid of the negativity affecting our life in every possible way: reading books on the subject, taking part in training courses. Everyone is looking for the system to be always productive and achieve every goal. If there is still something missing to live the life of your dreams, it is not your fault... Unfortunately, this is what you have been taught and it does not make you able to change. It happens because you did not use neuroplasticity.
Adult Neurogenesis: Beyond Rats and Mice by Luca Bonfanti,Irmgard Amrein Pdf
Researchers working on adult neurogenesis have focused largely on inbred laboratory rodents. While this provides a strong advantage of restricting genetic variation in the group, it also narrows our perspective on adult neurogenesis as a biological phenomenon. Many unsolved issues and open questions cannot be resolved without the contribution of comparative studies spanning through widely different species: how did adult neurogenesis evolve, what is the link between adult neurogenesis and brain complexity, how do adult neurogenesis and animal behavior influence each other, how does adult neurogenesis contribute to brain plasticity, cognition and, possibly, repair, and how do experimental conditions affect adult neurogenesis. The main message from the comparative approach to adult neurogenesis is that the relative exclusive focus on laboratory rodents can result in a bias on how we think about this biological process.
Plasticity in the Adult Brain: From Genes to Neurotherapy by M.A. Hofman,G.J. Boer,E.J.W. Van Someren,J. Verhaagen,D.F. Swaab,A.J.G.D. Holtmaat Pdf
In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.
Author : Joseph I. Tracy,Benjamin M. Hampstead,K. Sathian Publisher : Oxford University Press, USA Page : 433 pages File Size : 50,6 Mb Release : 2014-12-02 Category : Medical ISBN : 9780199965243
Cognitive Plasticity in Neurologic Disorders by Joseph I. Tracy,Benjamin M. Hampstead,K. Sathian Pdf
This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.
Neuroplasticity and Rehabilitation by Sarah A. Raskin Pdf
Brain plasticity is the focus of a growing body of research with significant implications for neurorehabilitation. This state-of-the-art volume explores ways in which brain-injured individuals may be helped not only to compensate for their loss of cognitive abilities, but also possibly to restore those abilities. Expert contributors examine the extent to which damaged cortical regions can actually recover and resume previous functions, as well as how intact regions are recruited to take on tasks once mediated by the damaged region. Evidence-based rehabilitation approaches are reviewed for a range of impairments and clinical populations, including both children and adults.
