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Author : Roger A. Brumback,Jeffery W. Gerst
Publisher : Wiley-Blackwell
Page : 384 pages
File Size : 47,8 Mb
Release : 1984
Category : Myoneural junction
ISBN : UCAL:B4525908
Author : Matthew N. Meriggioli,James F. Howard Jr.,C. Michel Harper Jr.
Publisher : CRC Press
Page : 320 pages
File Size : 55,6 Mb
Release : 2003-10-21
Category : Medical
ISBN : 9780203912966
This resource covers all aspects of the diagnosis and clinical management of patients with diseases of the neuromuscular junction. It breaks down each disease by pathophysiology, clinical presentation and natural history and course for improved diagnosis and treatment.
Author : Henry J. Kaminski
Publisher : Springer Science & Business Media
Page : 396 pages
File Size : 40,7 Mb
Release : 2002-10-03
Category : Medical
ISBN : 9781592593415
An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.
Author : George A. Mashour,Ralph Lydic
Publisher : Oxford University Press
Page : 296 pages
File Size : 47,6 Mb
Release : 2011-10-05
Category : Medical
ISBN : 9780190453305
Although the perioperative care of patients by anesthesiologists draws on diverse clinical skills, the principles of anesthesiology and pain management are rooted in the neurosciences. The Neuroscientific Foundations of Anesthesiology thoroughly examines the anesthetic modulation of the central, peripheral, and autonomic nervous systems and will help redefine anesthesiology as a fundamentally neuroscientific field. The book is organized by sections, with each focusing on a different part of the nervous system. State-of-the-art chapters written by thought-leaders in anesthesiology and neuroscience provide a novel and invaluable resource.
Author : R.E.M. Bowden,J. Maglagan,E. Zaimis,B. Collier,R.D. Dripps,L.W. Duchen,G.E. Hale Enderby,B.L. Ginsborg,S. Head,F. Hobbiger,D.H. Jenkinson,F.C. MacIntosh,S.E. Smith
Publisher : Springer Science & Business Media
Page : 758 pages
File Size : 48,8 Mb
Release : 2013-03-13
Category : Medical
ISBN : 9783642454769
Has the neuromuscular junction been over-exposed or is it perhaps already a closed book? I asked myself this at a recent International Congress when an American colleague complained that the Journal of Physiology had articles on nothing but the neuromuscular junction, while another colleague asked why I was editing a volume on a subject about which everything was already known. It is worrying to think that these views may be shared by other people. I hope that this volume will convince my two colleagues and other readers that the neuromuscular junction is very much alive and continues to attract the interest of many workers from a variety of fields; strange as it may seem, the synapse between a motor nerve ending and muscle fibre, with its relatively simple architecture, is one of the most inter esting sites in the body-I do hope we have done it justice. The various chapters of this volume present a cross section of knowledge as viewed by a group of 13 individuals, actively engaged in research. Multi-author volumes such as this are frequently criticised on the grounds that chapters or sec tions overlap. I believe that such criticium is only valid where the overlap is repetitious. Where it results in the reader having available discussions of material from differing stand-points, overlap becomes a valuable feature of this type of publication.
Author : Ruth Herbst,Hanns Lochmuller,Laure Strochlic,Inga Koneczny
Publisher : Frontiers Media SA
Page : 241 pages
File Size : 44,9 Mb
Release : 2022-01-17
Category : Science
ISBN : 9782889740406
Author : Jun Kimura
Publisher : Oxford University Press
Page : 1177 pages
File Size : 48,5 Mb
Release : 2013-10
Category : Medical
ISBN : 9780199738687
Intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and for neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG) this book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test.
Author : Miriam M. Salpeter
Publisher : Unknown
Page : 464 pages
File Size : 52,9 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015011645333
Author : Lawrence C. Sellin,Rolf Libelius,Stephen Thesleff
Publisher : Elsevier Publishing Company
Page : 678 pages
File Size : 53,9 Mb
Release : 1989
Category : Myoneural junction
ISBN : UOM:39015015452314
Author : Francesco Clementi
Publisher : Elsevier
Page : 249 pages
File Size : 46,8 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323159180
Neurotransmitter Release: The Neuromuscular Junction is a collection of papers presented at a small meeting organized in the University of Milan to honor Bruno Ceccarelli. Ceccarelli was particularly interested in the structure and functioning of the neuromuscular junction and spent the rest of his career characterizing the process of neurotransmitter release, and eventually providing the strongest available support for the widely accepted ""vesicle hypothesis"" of neurotransmitter release. The meeting was intended to gather as many scientists who had been directly in touch with Bruno as possible and to discuss together problems of Bruno's interest. Organized into 20 chapters, the book first discusses the organelles of distinct secretory pathways involved in distinct types of neuronal signaling, such as synapsins, synaptophysin , and synaptobrevin. It then examines the role of coated vesicles, acetylcholine compartments, and potassium and calcium channels on neurotransmission processes. Other topics considered are the regeneration of nerve-evoked neurotransmission; the single-channel recordings of KNa in avian sensory neurons; the modulation of voltage-dependent calcium currents in identified snail neurons; and the agonistic/antagonistic action of calcium channel in mammalian peripheral neurons. Cross-talks between receptors coupled to calcium currents and between different intracellular signaling are provided in the last chapters of the book. These chapters also look into the relevance of lipoxygenase metabolites of arachidonic acid to cell-to-cell communication in the central nervous system. This book is an invaluable source for scientists, researchers, and students who are interested in basic neurology.
Author : Patricia A. Pierce
Publisher : Springer Science & Business Media
Page : 540 pages
File Size : 46,5 Mb
Release : 2013-06-29
Category : Science
ISBN : 9781489910165
This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.
Author : Anonim
Publisher : Academic Press
Page : 289 pages
File Size : 51,7 Mb
Release : 1999-04-29
Category : Medical
ISBN : 0080857779
Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach. This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories. Key Features * Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system * Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function * Written in clear language that is easily understandable to readers not already familiar with fruit fly research * Includes numerous diagrams and extensive reference lists
Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Page : 2902 pages
File Size : 53,9 Mb
Release : 2011-03-10
Category : Medical
ISBN : 9781139497022
In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.
Author : Andreas Rummel,Thomas Binz
Publisher : Springer
Page : 0 pages
File Size : 51,7 Mb
Release : 2015-01-29
Category : Medical
ISBN : 3642448895
The extremely potent substance botulinum neurotoxin (BoNT) has attracted much interest in diverse fields. Originally identified as cause for the rare but deadly disease botulism, military and terrorist intended to misuse this sophisticated molecule as biological weapon. This caused its classification as select agent category A by the Centers for Diseases Control and Prevention and the listing in the Biological and Toxin Weapons Convention. Later, the civilian use of BoNT as long acting peripheral muscle relaxant has turned this molecule into an indispensable pharmaceutical world wide with annual revenues >$1.5 billion. Also basic scientists value the botulinum neurotoxin as molecular tool for dissecting mechanisms of exocytosis. This book will cover the most recent molecular details of botulinum neurotoxin, its mechanism of action as well as its detection and application.
Author : Nassir H. Sabah
Publisher : CRC Press
Page : 575 pages
File Size : 55,5 Mb
Release : 2020-11-29
Category : Medical
ISBN : 9781000191363
This book is rather unique in its approach and coverage. The approach is essentially that of an engineering textbook, emphasizing the quantitative aspects and highlighting the fundamentals and basic concepts involved. The coverage progresses in a logical and systematic manner from the subcellular, starting with the electrophysiology of the cell membrane, then proceeding to synapses, neurons, and muscle, before considering neuronal motor ensembles and the neuromuscular system as a whole. Simple, clear, and comprehensive explanations are given throughout. After an introductory chapter on some background material in biology, biophysics, and chemical kinetics, a substantial part of the book (Chapters 2-8) necessarily covers in considerable detail the basic components and processes that underlie the electrical and associated activities of the nervous system. The remaining chapters of the book (Chapters 9-13) focus on the neuromuscular system, starting with the structure of muscle cells, the generation of force by muscular contraction, and muscle receptors. The last chapter examines aspects of the control of movement, motor learning and memory, the maintenance of posture, and locomotion, and critically examines some of the theories that have been advanced to explain how movement is controlled. The book is intended for undergraduate or graduate students in the natural sciences, mathematics, or engineering who seek a deeper understanding of the fundamentals of neuroscience and the somatomotor system, in accordance with the aforementioned objectives. The book can serve as a textbook for a one-semester course on the neuromuscular system or as a reference in a more general course on neuroscience. Provides a thorough analytical treatment of membrane electrophysiology, starting from the first principles Emphasizes strongly the basic and fundamental concepts throughout Discusses thoroughly the essential features and properties of the basic constituents of the nervous system, that is, neurons and synapses, including the neuromuscular junction Explains the main aspects of posture, locomotion, and control of movement Includes practice problems throughout the text and a solutions manual will be available for adopting professors Nassir Sabah is professor of biomedical engineering in the electrical and computer engineering department at the American University of Beirut, Lebanon. He received his B.Sc. (Hons. Class I) and his M.Sc. in electrical engineering from the University of Birmingham, U.K., and his Ph.D. in biophysical sciences from the State University of New York (SUNY/Buffalo). He has served as Chairman of the Electrical Engineering Department, Director of the Institute of Computer Studies, and Dean of the Faculty of Engineering and Architecture at the American University of Beirut. In these capacities, he was responsible for the development of programs, curricula, and courses in electrical, biomedical, communications, and computer engineering. Professor Sabah has extensive professional experience in the fields of electrical engineering, electronics, and computer systems, with more than 35 years’ teaching experience in neuroengineering, biomedical engineering, electronics, and electric circuits. He has over 100 technical publications, mainly in neurophysiology, biophysics, and biomedical instrumentation. He has served on numerous committees and panels in Lebanon and the region. He is a Fellow of the Institution of Engineering and Technology (IET, U.K.), a member of the American Association for the Advancement of Science (AAAS), and a member of the American Society for Engineering Education (ASEE).
