Neuroprogression In Psychiatry

Author : Flávio Kapczinski,Michael Berk,Pedro Vieira da Silva Magalhães
Publisher : Oxford University Press
Page : 272 pages
File Size : 45,8 Mb
Release : 2019-03-06
Category : Medical
ISBN : 9780191090875

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Neuroprogression in Psychiatry by Flávio Kapczinski,Michael Berk,Pedro Vieira da Silva Magalhães Pdf

Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.

Author : A. Halaris,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Page : 182 pages
File Size : 53,8 Mb
Release : 2017-07-25
Category : Medical
ISBN : 9783318060515

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Neuroprogression in Psychiatric Disorders by A. Halaris,B.E. Leonard Pdf

In this volume, international experts critically review cutting-edge advances in neuroprogression research. The relevance of these findings to psychiatric and neurological disorders is clarified. Potential etiopathological mechanisms of neuroprogression are described in detail. Special emphasis is placed on the role of the immune system in stress and stress-related disorders and brain-immune interactions. The epigenetic consequences of adverse experiences in early childhood, which may prelude major psychiatric disorders, are also considered. Recent research has not only provided evidence of neuroprogression in psychiatric and neurological disorders, but has shown that pharmacologic interventions have the potential to arrest this process. Advances in testing and imaging will lead to timely diagnosis and earlier treatment. Identification of neurological mechanisms alongside (epi-)genetic vulnerability markers will create truly personalized treatment programs. This book is a valuable resource for everyone who wishes to gain insight into the essential features of the neuroprogressive course of major psychiatric and neurological disorders. In particular, psychiatrists, neuroscientists and neurologists ¬ as well as immunologists, pharmacologists and molecular biologists - will find very informative chapters of direct relevance to their field.

Author : Flávio Kapczinski,Pedro V. S. Magalhães,Michael Berk
Publisher : Unknown
Page : 128 pages
File Size : 51,8 Mb
Release : 2019
Category : Mental illness
ISBN : 0191829226

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Neuroprogression in Psychiatry by Flávio Kapczinski,Pedro V. S. Magalhães,Michael Berk Pdf

Author : Flávio Kapczinski,Eduard Vieta,Pedro V. S. Magalhães,Michael Berk
Publisher : Oxford University Press, USA
Page : 357 pages
File Size : 50,8 Mb
Release : 2015
Category : Medical
ISBN : 9780198709992

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Neuroprogression and Staging in Bipolar Disorder by Flávio Kapczinski,Eduard Vieta,Pedro V. S. Magalhães,Michael Berk Pdf

Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--

Author : Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta
Publisher : Academic Press
Page : 472 pages
File Size : 41,5 Mb
Release : 2020-11-25
Category : Medical
ISBN : 9780128191835

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Neurobiology of Bipolar Disorder by Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta Pdf

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Author : Jean-Marc Cavaillon,Mervyn Singer
Publisher : John Wiley & Sons
Page : 1818 pages
File Size : 50,8 Mb
Release : 2018-02-20
Category : Medical
ISBN : 9783527338993

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Inflammation, 4 Volume Set by Jean-Marc Cavaillon,Mervyn Singer Pdf

The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.

Author : Ather Muneer
Publisher : Routledge
Page : 212 pages
File Size : 54,9 Mb
Release : 2018-02-01
Category : Medical
ISBN : 9781351370776

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Mood Disorders by Ather Muneer Pdf

Mood Disorders: Practical Issues in Diagnosis and Management provides cutting edge knowledge about the diagnosis and treatment of principal mood disorders, namely major depressive disorder and bipolar disorder. Covering diagnosis, differentiating features, and illness course and trajectories of principal mood disorders, Dr. Ather Muneer provides essential information in a succinct and practical manner, while highlighting significant new findings in the area. This book will help a broad range of mental health professionals better treat the millions of people with mood disorders across the globe.

Author : Bernhard Baune
Publisher : Academic Press
Page : 636 pages
File Size : 55,7 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9780128110744

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Inflammation and Immunity in Depression by Bernhard Baune Pdf

Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions

Author : Allan H. Young,Mario F. Juruena
Publisher : Springer Nature
Page : 325 pages
File Size : 45,9 Mb
Release : 2021-03-29
Category : Medical
ISBN : 9783030721435

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Bipolar Disorder: From Neuroscience to Treatment by Allan H. Young,Mario F. Juruena Pdf

Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.

Author : Johannes Hebebrand,Beate Herpertz-Dahlmann
Publisher : Elsevier Health Sciences
Page : 400 pages
File Size : 55,6 Mb
Release : 2018-12-07
Category : Medical
ISBN : 9780323548533

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Eating Disorders and Obesity in Children and Adolescents by Johannes Hebebrand,Beate Herpertz-Dahlmann Pdf

Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. Consolidates today’s available information on this timely topic into a single convenient resource.

Author : David Linden
Publisher : Oxford University Press
Page : 161 pages
File Size : 47,9 Mb
Release : 2016
Category : Medical
ISBN : 9780198739609

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Neuroimaging and Neurophysiology in Psychiatry by David Linden Pdf

Neuroimaging and Neurophysiology in Psychiatry is an invaluable guide through the methods and applications of neuroimaging and neurophysiology.

Author : David Castle,David Coghill
Publisher : Cambridge University Press
Page : 287 pages
File Size : 48,8 Mb
Release : 2021-03-11
Category : Medical
ISBN : 9781108740425

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Comprehensive Men's Mental Health by David Castle,David Coghill Pdf

A complete and accessible textbook covering current understandings about how mental health issues affect men, and the available treatments.

Author : Ives Cavalcante Passos,Benson Mwangi,Flávio Kapczinski
Publisher : Springer
Page : 180 pages
File Size : 54,9 Mb
Release : 2019-02-12
Category : Medical
ISBN : 9783030035532

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Personalized Psychiatry by Ives Cavalcante Passos,Benson Mwangi,Flávio Kapczinski Pdf

This book integrates the concepts of big data analytics into mental health practice and research. Mental disorders represent a public health challenge of staggering proportions. According to the most recent Global Burden of Disease study, psychiatric disorders constitute the leading cause of years lost to disability. The high morbidity and mortality related to these conditions are proportional to the potential for overall health gains if mental disorders can be more effectively diagnosed and treated. In order to fill these gaps, analysis in science, industry, and government seeks to use big data for a variety of problems, including clinical outcomes and diagnosis in psychiatry. Multiple mental healthcare providers and research laboratories are increasingly using large data sets to fulfill their mission. Briefly, big data is characterized by high volume, high velocity, variety and veracity of information, and to be useful it must be analyzed, interpreted, and acted upon. As such, focus has to shift to new analytical tools from the field of machine learning that will be critical for anyone practicing medicine, psychiatry and behavioral sciences in the 21st century. Big data analytics is gaining traction in psychiatric research, being used to provide predictive models for both clinical practice and public health systems. As compared with traditional statistical methods that provide primarily average group-level results, big data analytics allows predictions and stratification of clinical outcomes at an individual subject level. Personalized Psychiatry – Big Data Analytics in Mental Health provides a unique opportunity to showcase innovative solutions tackling complex problems in mental health using big data and machine learning. It represents an interesting platform to work with key opinion leaders to document current achievements, introduce new concepts as well as project the future role of big data and machine learning in mental health.

Author : Gin S. Malhi,Marc Masson,Frank Bellivier
Publisher : Springer
Page : 342 pages
File Size : 54,9 Mb
Release : 2016-11-24
Category : Medical
ISBN : 9783319459233

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The Science and Practice of Lithium Therapy by Gin S. Malhi,Marc Masson,Frank Bellivier Pdf

This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide, and those that are recipients of lithium therapy.

Author : Jair Soares,Consuelo Walss-Bass,Paolo Brambilla
Publisher : Academic Press
Page : 0 pages
File Size : 51,5 Mb
Release : 2018-06-12
Category : Medical
ISBN : 0128123478

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Bipolar Disorder Vulnerability by Jair Soares,Consuelo Walss-Bass,Paolo Brambilla Pdf

Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.