Neurotoxicity Of Nanomaterials And Nanomedicine

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Neurotoxicity of Nanomaterials and Nanomedicine

Author : Xinguo Jiang,Huile Gao
Publisher : Academic Press
Page : 358 pages
File Size : 54,8 Mb
Release : 2016-10-03
Category : Medical
ISBN : 9780128046203

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Neurotoxicity of Nanomaterials and Nanomedicine by Xinguo Jiang,Huile Gao Pdf

Neurotoxicity of Nanomaterials and Nanomedicine presents an overview of the exciting research in neurotoxicity and nanomaterials. Nanomaterials have been extensively used in medicine, including diagnosis probes, drug carriers, and embedded materials. While some have been approved for clinical use, most nanomaterials are waiting to be transferred from lab to clinic. However, the toxicity is a main barrier that restricts the translation. This comprehensive book includes chapters on the most commonly used individual nanoparticles, with information on the applications, neurotoxicity, and related mechanisms of each, providing the most in-depth and current information available. The book examines the pathways that nanomaterials enter into, and eliminate, from the brain, along with the strategies that could reduce the neurotoxicity of nanomaterials. Providing a background to the subject, detailed information, and ideas for future directions in research, the book is essential for students and researchers in toxicology, and for those in medicine, neurology, pharmacology, pharmaceutical science, and materials science who are researching nanomaterials. Presents a thorough discussion of the most common nanoparticles in the brain and their neurotoxicology Includes the most common nanoparticles, their applications, and mechanisms Provides one of the first books to focus on nanomedicine and neurotoxicity

Nanomaterials Safety

Author : Shyamasree Ghosh
Publisher : Walter de Gruyter GmbH & Co KG
Page : 288 pages
File Size : 55,5 Mb
Release : 2018-11-19
Category : Science
ISBN : 9783110578362

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Nanomaterials Safety by Shyamasree Ghosh Pdf

This monograph summarizes the current knowledge on potential health hazards induced by nanomaterials from different sources and sort such as food, drugs and silver nanoparticles. Methods to assess toxicity as well as known effects on the genome, neuronal and respiratory system are discussed. Besides the impact on human and animal life the books also addresses aquatic toxicity.

Handbook of Safety Assessment of Nanomaterials

Author : Bengt Fadeel
Publisher : CRC Press
Page : 565 pages
File Size : 43,7 Mb
Release : 2014-12-10
Category : Medical
ISBN : 9789814463362

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Handbook of Safety Assessment of Nanomaterials by Bengt Fadeel Pdf

The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.

Nanotoxicology

Author : Nancy A. Monteiro-Riviere,C. Lang Tran
Publisher : CRC Press
Page : 514 pages
File Size : 41,7 Mb
Release : 2014-03-03
Category : Medical
ISBN : 9781482203929

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Nanotoxicology by Nancy A. Monteiro-Riviere,C. Lang Tran Pdf

Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This in

Nanotechnology in Medicine

Author : Mahendra Rai,Mrunali Patel,Rashmin Patel
Publisher : John Wiley & Sons
Page : 448 pages
File Size : 46,5 Mb
Release : 2021-10-19
Category : Science
ISBN : 9781119769880

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Nanotechnology in Medicine by Mahendra Rai,Mrunali Patel,Rashmin Patel Pdf

NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.

Nanotoxicology

Author : Hemant Kumar Daima,S. L. Kothari,Bhargava Suresh Kumar
Publisher : CRC Press
Page : 494 pages
File Size : 55,8 Mb
Release : 2021-07-15
Category : Medical
ISBN : 9781000399912

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Nanotoxicology by Hemant Kumar Daima,S. L. Kothari,Bhargava Suresh Kumar Pdf

The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.

Nanomedicine in Brain Diseases

Author : Xue Xue
Publisher : Springer Nature
Page : 313 pages
File Size : 44,9 Mb
Release : 2019-11-07
Category : Science
ISBN : 9789811387319

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Nanomedicine in Brain Diseases by Xue Xue Pdf

This book provides an overview of the current applications of nanomaterials in brain diseases, and introduces several novel nanomaterials that have excellent potential in this field. During the last two decades, nanotechnology had matured significantly as it has transitioned from a bench-top science to an applied technology. However, the application of nanomaterials in basic and clinical neuroscience is still at an early stage, and understanding how the intrinsic properties of nanomaterials translate to complex biological responses is an area of intensive research. Part 1 of the book focuses on the principles and strategies of nanomedicine in the brain diseases, while part 2 examines the applications of promising nanomaterials for therapy and diagnosis in the brain. Together they offer a comprehensive picture of advances in nanotechnology and their successful use in treating brain diseases in the past 20 years.

Nanomedicine and the Nervous System

Author : Colin R. Martin,Victor R. Preedy,Ross J. Hunter
Publisher : CRC Press
Page : 434 pages
File Size : 42,6 Mb
Release : 2012-03-08
Category : Medical
ISBN : 9781578087280

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Nanomedicine and the Nervous System by Colin R. Martin,Victor R. Preedy,Ross J. Hunter Pdf

The nanosciences encompass a variety of technologies ranging from particles to networks and nanostructures. Nanoparticles can be suitable carriers of therapeutic agents, and nanostructures provide suitable platforms and scaffolds for sub-micro bioengineering. This book focuses on nanomedicine and nanotechnology as applied to the nervous system and the brain. It covers nanoparticle-based immunoassays, nanofiber microbrush arrays, nanoelectrodes, protein nanoassemblies, nanoparticles-assisted imaging, nanomaterials, and ion channels. Additional topics include stem cell imaging, neuronal performance, treatment of stroke and spinal cord injury, and lipid nanostructures.

Nanoparticles for Brain Drug Delivery

Author : Carla Vitorino,Andreia Jorge,Alberto A.C.C. Pais
Publisher : CRC Press
Page : 518 pages
File Size : 42,7 Mb
Release : 2021-03-15
Category : Medical
ISBN : 9781000245592

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Nanoparticles for Brain Drug Delivery by Carla Vitorino,Andreia Jorge,Alberto A.C.C. Pais Pdf

In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. The book encompasses general aspects pertaining to fundamental development, including tripartite in silico–in vitro–in vivo approaches. It also covers a diversity of nanomedicines applied in treatment and/or diagnosis and monitoring of CNS disorders. Aspects concerning their translation from the bench to clinical practice are also seamlessly discussed. This book will inspire readers to discover possible approaches to holistically delivering drugs into the brain. Edited by Carla Vitorino, Andreia Jorge and Alberto Pais, this book will appeal to anyone involved in nanomedicine, pharmaceutics, neurological and cancer therapies, drug delivery research and computational and regulatory sciences.

Nanopharmaceutics

Author : Xing-Jie Liang
Publisher : World Scientific
Page : 605 pages
File Size : 47,9 Mb
Release : 2013
Category : Medical
ISBN : 9789814368667

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Nanopharmaceutics by Xing-Jie Liang Pdf

Nanomaterials, with their unique size-dependent physical and chemical properties, have shown promising advantages as drug and gene delivery vehicles, ultra-sensitive intracellular detectors and novel therapeutic drugs. Nanopharmaceutics is one of the disciplines that will benefit the most from this technology. Nanotechnology will have a revolutionary impact on cancer diagnosis and therapy due to the exceptional characteristics of nanopharmaceutics. This book provides an overview of some tools, methods, and materials of nanotechnology that offer potential applications in pharmaceutics, followed by a series of examples showing applications that are already in development. It may very well inspire researchers to develop a new generation of pharmaceutics with inventive non-traditional approach and employ nanoscale science for the benefit of the patient.

Toxicity of Nanomaterials

Author : Suresh Pillai,Yvonne Lang
Publisher : CRC Press
Page : 259 pages
File Size : 41,7 Mb
Release : 2019-05-16
Category : Science
ISBN : 9780429556012

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Toxicity of Nanomaterials by Suresh Pillai,Yvonne Lang Pdf

Choice Recommended Title, April 2020 This comprehensive book, edited by two leading experts in nanotechnology and bioengineering with contributions from a global team of specialists, provides a detailed overview of the environmental and health impacts associated with the toxicology of nanomaterials. Special attention is given to nanomaterial toxicity during synthesis, production and application, and chapters throughout are focused on key areas that are important for future research and development of nanomaterials. This book will be of interest to advanced students studying biomedical engineering and materials science, PhD researchers, post-docs and academics working in the area of nanotechnology, medicine, manufacturing and regulatory bodies. Features: Collates and critically evaluates various aspects of the toxicology of nanomaterials in one comprehensive text Discusses the various effects of nanocrystals including the morphologies on cytotoxicity, in addition to the environmental and cytotoxicity risks of graphene and 2D nanomaterials Explores practical methods of detection and quantification, with applications in the environmental and healthcare fields

Nanomedicine

Author : Yi Ge,Songjun Li,Shenqi Wang,Richard Moore
Publisher : Springer
Page : 413 pages
File Size : 53,8 Mb
Release : 2014-12-01
Category : Science
ISBN : 9781461421405

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Nanomedicine by Yi Ge,Songjun Li,Shenqi Wang,Richard Moore Pdf

Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.

Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology

Author : Saura C. Sahu,Daniel A. Casciano
Publisher : John Wiley & Sons
Page : 440 pages
File Size : 42,9 Mb
Release : 2014-04-22
Category : Science
ISBN : 9781118855867

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Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology by Saura C. Sahu,Daniel A. Casciano Pdf

The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.

Biomedical Applications and Toxicity of Nanomaterials

Author : P. V. Mohanan,Sudha Kappalli
Publisher : Springer Nature
Page : 771 pages
File Size : 54,5 Mb
Release : 2023-05-08
Category : Medical
ISBN : 9789811978340

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Biomedical Applications and Toxicity of Nanomaterials by P. V. Mohanan,Sudha Kappalli Pdf

This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.

Principles of Nanomedicine

Author : Sourav Bhattacharjee
Publisher : CRC Press
Page : 562 pages
File Size : 42,5 Mb
Release : 2019-10-18
Category : Medical
ISBN : 9780429632051

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Principles of Nanomedicine by Sourav Bhattacharjee Pdf

The scope of nanotechnology in medical applications has expanded fast in the last two decades. With their unprecedented material properties, nanoscale materials present with unorthodox opportunities in a wide range of domains, including drug delivery and medical imaging. This book assembles the various facets of nanomedicine while discussing key issues such as physicochemical properties that enhance the appeal of nanomedicine. The book is an excellent resource for physicians, PhDs, and postdocs involved in nanomedicine research to learn and understand the scope and complexity of the subject. It begins with a short history of nanotechnology, followed by a discussion on the fundamental concepts and extraordinary properties of nanoscale materials, and then slowly unfolds into multiple chapters illustrating the uses of various nanomaterials in drug delivery, sensing, and imaging.