Neurotransmitters And Drugs

Author : Roy Webster
Publisher : John Wiley & Sons
Page : 550 pages
File Size : 41,6 Mb
Release : 2001-11-28
Category : Medical
ISBN : 0471978191

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Neurotransmitters, Drugs and Brain Function by Roy Webster Pdf

Neurotransmitters, Drugs and Brain Function aims to link basic aspects of the activity of neurotransmitters at the receptor and synaptic level with their role in normal brain function, disease states, and drug action. Thus, the material considers to what extent our knowledge of the central synaptic action of certain drugs can explain their possible roles in the cause of diseases and in the modes of action of drugs effective in those conditions. It offers a working explanation of drug and neurotransmitter action in CNS function, with a clear, comprehensive, and challenging style of writing. The authors review the chemical basis for drugs and the conditions they treat. It also, includes numerous illustrations and schematic diagrams.

Author : Zygmunt L. Kruk
Publisher : Springer
Page : 211 pages
File Size : 44,6 Mb
Release : 2014-11-14
Category : Science
ISBN : 9781461575177

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Neurotransmitters and Drugs by Zygmunt L. Kruk Pdf

Author : Z.L. Kruk,C. Pycock
Publisher : Springer Science & Business Media
Page : 211 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401131346

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Neurotransmitters and Drugs by Z.L. Kruk,C. Pycock Pdf

This book is intended for students of medicine, pharmacy and other biological disciplines, who want to have a working knowledge of the mechanisms of action, uses and adverse effects of drugs which modify the activity of neurotransmitters in the peripheral and central nervous systems. It is suitable for undergraduates and for post-graduates on taught higher degree courses and diplomas. New information and concepts have been incorporated into the text as appropriate, and references have been updated. Excitatoryand inhibitory amino acids are considered in two chapters, and the last chapter of the first two editions (which considered drugs which do not interact selectively with neurotransmitters) has been subsumed into other sections. The third edition follows the tried format of previous editions. Following a chapter which introduces the biology and pharmacology of neurotransmission, subsequent chapters deal with synthesis, storage, release, receptors and inactivation of individual neurotransmitters, together with a consideration of therapeutic uses and mechanisms of adverse effects.

Author : Leslie Iversen
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 47,7 Mb
Release : 2013-11-11
Category : Psychology
ISBN : 9781468431803

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Drugs, Neurotransmitters, and Behavior by Leslie Iversen Pdf

The first six volumes of the Handbook reviewed basic neuropharmacology, drawing on expertise in biochemistry, pharmacology and electrophysiology. The next three volumes focus attention on the functional importance of these basic neuropharmacological mechanisms for normal behavior. In order to study this interface in the intact functioning organism, appropriate methods for describing and quantifying behavior must be developed. The past twenty years have witnessed a revolution in the study of behavior which has taken us away from the often fruitless theoretical arguments to descriptive behaviorism. Technical achievements in the design of apparatus and the recording of behavior played an important role in these and the resultant behavioral methods have been accepted and developments, found useful in studying the effects of drugs. The development of psycho pharmacology as a discipline owes as much to these behavioral methods as it does to the basic neuropharmacological techniques pioneered for in vitro studies. In the first section of Volume 7, an effort has been made to provide reviews both of theory and practice in behavioral science. Milner's chapter deals with the concept of motivation in a theoretical framework. By contrast, the chapters by Morse et ai. and Dews and DeWeese provide a more descriptive view of the various ways in which aversive stimuli control behavior and the importance of schedules of reinforcement in determining the profile of responding in the animal. The equal importance of observational behav ioral methods is well illustrated by Mackintosh et ai.

Author : David P. Friedman,Sue Rusche
Publisher : CRC Press
Page : 214 pages
File Size : 52,9 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203304976

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False Messengers by David P. Friedman,Sue Rusche Pdf

This book provides a scientific explanation of drug abuse and addiction for the general public. It clarifies the meaning of concepts such as intoxication, physical dependence, and addiction, and describes the changes in the brain that underlie these states. Indeed, this volume is unique because it presents a comprehensive picture of what actually happens to people and their brains when they chronically self-administer opiates, stimulants or alcohol. Complex mechanisms of drug action in the brain are made simple and comprehensible to the layman through use of informative analogies and salient graphics. Accounts of the effects of drug use and abuse on normal people create meaningful, easy-to-relate-to examples from everyday life.

Author : A. Mandell
Publisher : Springer Science & Business Media
Page : 320 pages
File Size : 47,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461345749

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New Concepts in Neurotransmitter Regulation by A. Mandell Pdf

Historically, the development of biological science has proceeded from the anatomy to the physiology of particular systems. Knowledge about neurotransmitters in the brain has evolved from the discovery of the compounds per set through the elucidation of their biosynthetic and degradative pathways, and finally to the current focus, the regulation of these processes. Regulation in a biological system implies the capacity to respond to perturbations. The introduction of standard and speci fiable disturbances in a biological system followed by examination of the mechanisms involved in response, i.e. that dampen and/or cancel the induced changes, has proved to be a successful way to elucidate regulatory mechanisms. Psychotropic drugs have been most useful to students of regula tory mechanisms in that calvarial prisoner, the brain, for they allow prospective manipulation of variables like dosage and time. Those of us interested in the biological substrata of behavior are especially excited that disturbance induced by drugs leaves the organism intact and behaving, and we can observe behavioral correlates. The pharmacological strategy is, of course, not unique to brain scientists. The relationship between psychotropic drugs and our emerging knowledge of neurotransmitter regulation is, for example, akin to the development of anticancer agents in company with the uncovering of many mysteries of molecular biology.

Author : Anonim
Publisher : Unknown
Page : 24 pages
File Size : 42,5 Mb
Release : 1993
Category : Drug abuse
ISBN : UOM:39015032482252

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A Viewer's Guide by Anonim Pdf

Author : Zygmunt L. Kruk,Christopher J. Pycock
Publisher : Unknown
Page : 128 pages
File Size : 51,5 Mb
Release : 1972
Category : Electronic
ISBN : OCLC:249158310

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Neurotransmitters and Drugs by Zygmunt L. Kruk,Christopher J. Pycock Pdf

Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Page : 74 pages
File Size : 42,8 Mb
Release : 2011-08-05
Category : Medical
ISBN : 9780309212212

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Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System by Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders Pdf

Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarkers, currently exist for measuring glutamate pathology in CNS disorders or injuries. Glutamate dysfunction has been associated with an extensive range of nervous system diseases and disorders. Problems with how the neurotransmitter glutamate functions in the brain have been linked to a wide variety of disorders, including schizophrenia, Alzheimer's, substance abuse, and traumatic brain injury. These conditions are widespread, affecting a large portion of the United States population, and remain difficult to treat. Efforts to understand, treat, and prevent glutamate-related disorders can be aided by the identification of valid biomarkers. The Institute of Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop on June 21-22, 2010, to explore ways to accelerate the development, validation, and implementation of such biomarkers. Glutamate-Related Biomarkers in Drug Development for Disorders of the Nervous System: Workshop Summary investigates promising current and emerging technologies, and outlines strategies to procure resources and tools to advance drug development for associated nervous system disorders. Moreover, this report highlights presentations by expert panelists, and the open panel discussions that occurred during the workshop.

Author : Barry Stimmel
Publisher : Routledge
Page : 144 pages
File Size : 49,9 Mb
Release : 2014-06-03
Category : Psychology
ISBN : 9781317840824

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Opiate Receptors, Neurotransmitters, and Drug Dependence by Barry Stimmel Pdf

Experts address the role of neuromodulators and opiate receptors in alcohol and drug dependence. They present innovative research techniques, new discoveries, and possible clinical correlates that allow for a much greater understanding of the clinical phenomena surrounding alcohol and narcotic use. Included in this thought-provoking volume are a comprehensive review of the current knowledge of the endogenous opiates, their interactions with the opiate receptors, and the potential relationship that these substances might have in promoting the development of dependence, tolerance, and withdrawal; the translation of the basic physiologic findings occuring during withdrawal to treatment of withdrawal symptoms in the clinical setting; and a physiological explanation for the rationale of using clonidine and naltrexone to accelaerate the detoxification process without undue discomfort.

Author : Institute of Medicine,Committee on Opportunities in Drug Abuse Research
Publisher : National Academies Press
Page : 330 pages
File Size : 47,9 Mb
Release : 1996-11-01
Category : Medical
ISBN : 9780309055338

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Pathways of Addiction by Institute of Medicine,Committee on Opportunities in Drug Abuse Research Pdf

Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

Author : Zygmunt L. Kruk
Publisher : Springer
Page : 0 pages
File Size : 48,9 Mb
Release : 1991-06-15
Category : Science
ISBN : 9401131325

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Neurotransmitters and Drugs by Zygmunt L. Kruk Pdf

This book is intended for students of medicine, pharmacy and other biological disciplines, who want to have a working knowledge of the mechanisms of action, uses and adverse effects of drugs which modify the activity of neurotransmitters in the peripheral and central nervous systems. It is suitable for undergraduates and for post-graduates on taught higher degree courses and diplomas. New information and concepts have been incorporated into the text as appropriate, and references have been updated. Excitatory and inhibitory amino acids are considered in two chapters, and the last chapter of the first two editions (which considered drugs which do not interact selectively with neurotransmitters) has been subsumed into other sections. The third edition follows the tried format of previous editions. Following a chapter which introduces the biology and pharmacology of neurotransmission, subsequent chapters deal with synthesis, storage, release, receptors and inactivation of individual neurotransmitters, together with a consideration of therapeutic uses and mechanisms of adverse effects.

Author : Anonim
Publisher : Unknown
Page : 76 pages
File Size : 40,8 Mb
Release : 2007
Category : Brain
ISBN : MINN:31951D025861296

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Drugs, Brains, and Behavior by Anonim Pdf

Author : Walter B. Essman
Publisher : Unknown
Page : 230 pages
File Size : 54,5 Mb
Release : 1980
Category : Acetylcholine
ISBN : UOM:39015004419787

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Neurotransmitters, Receptors & Drug Action by Walter B. Essman Pdf

Author : Dr. Anna Lembke
Publisher : Penguin
Page : 305 pages
File Size : 41,7 Mb
Release : 2021-08-24
Category : Psychology
ISBN : 9781524746735

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Dopamine Nation by Dr. Anna Lembke Pdf

INSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER “Brilliant . . . riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of Dopesick, as heard on Fresh Air This book is about pleasure. It’s also about pain. Most important, it’s about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We’re living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting . . . The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we’ve all become vulnerable to compulsive overconsumption. In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain . . . and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery.