New Weapons To Control Bacterial Growth

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New Weapons to Control Bacterial Growth

Tomas G. Villa,Miguel Vinas
New Weapons to Control Bacterial Growth Book PDF

Author : Tomas G. Villa,Miguel Vinas
Publisher : Springer
Page : 556 pages
File Size : 53,6 Mb
Release : 2016-03-24
Category : Science
ISBN : 9783319283685

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New Weapons to Control Bacterial Growth by Tomas G. Villa,Miguel Vinas Pdf

Written by specialists in the different fields, this book presents new perspectives and insights into strategies and weapons to fight microbial infections. It also reviews the “state of the art” of alternative treatment approaches and new therapeutic agents to deal with infections caused by multidrug-resistant microorganisms. In an era of accumulated resistance to current antibiotics, it is vital that this is undertaken without further delay. Aspects discussed include the control of RNA synthesis, the use of bacteriocins or enzybiotics (bacteriophages or purified lysins), the specific control of pathogenic clostridia, the design of new drugs affecting DNA synthesis in bacteria, the use of fecal-matter transplant strategies, the specific control of quorum sensing responses in bacteria, the use of new peptides as antibiotics and new ways to control bacteria that cause cancer, such as Helicobacter pylori cancers.

Pharmaceuticals from Microbes

Divya Arora,Chetan Sharma,Sundeep Jaglan,Eric Lichtfouse
Pharmaceuticals from Microbes Book PDF

Author : Divya Arora,Chetan Sharma,Sundeep Jaglan,Eric Lichtfouse
Publisher : Springer
Page : 212 pages
File Size : 51,9 Mb
Release : 2019-01-09
Category : Science
ISBN : 9783030018818

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Pharmaceuticals from Microbes by Divya Arora,Chetan Sharma,Sundeep Jaglan,Eric Lichtfouse Pdf

This book has been assembled with the hope of being an authoritative, comprehensive, conceptually sound and highly informative compilation of recent advances describing the concepts of bioengineering in the field of microbiology. It comprises of seven chapters written by eminent authors in their respective fields. Topics included deal with the significant advancement of microbial technology with emphasis on drug delivery strategies for healthcare products, vaccine delivery, biotransformation approaches to generate new molecules, upstream/downstream processing of biopharmaceuticals. It serves as excellent reference material for researchers, students and academicians in the fields of biotechnology, microbiology and pharmaceutical sciences.

Novel Approaches in Biopreservation for Food and Clinical Purposes

Enriqueta Garcia-Gutierrez,Natalia Gomez-Torres,Sara Arbulu
Novel Approaches in Biopreservation for Food and Clinical Purposes Book PDF

Author : Enriqueta Garcia-Gutierrez,Natalia Gomez-Torres,Sara Arbulu
Publisher : CRC Press
Page : 314 pages
File Size : 54,9 Mb
Release : 2024-02-06
Category : Technology & Engineering
ISBN : 9781003854005

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Novel Approaches in Biopreservation for Food and Clinical Purposes by Enriqueta Garcia-Gutierrez,Natalia Gomez-Torres,Sara Arbulu Pdf

The aim of "Novel Approaches in Biopreservation for Food and Clinical Purposes" is to provide cutting-edge information on biopreservation methods for both food and medical applications. The book has one chapter dedicated to each major food category (milk and dairy, vegetables, meat, fish, bread, flours and beverages) and brief chapters covering preservation approaches for pharmaceuticals, embryos, gametes, cells and tissues. This book assumes a basic understanding of microbiology and food science, aiming to offer an overview of the most commonly and updated techniques currently used, including protective cultures and fermentation starters, bacterial metabolites, essential oils, bacteriophages or endolysins. By presenting this comprehensive overview, the book aims to advance knowledge in the field of biopreservation and foster its implementation in both food and clinical contexts.

Biodefense in the Age of Synthetic Biology

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Biodefense in the Age of Synthetic Biology Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Publisher : National Academies Press
Page : 189 pages
File Size : 49,9 Mb
Release : 2019-01-05
Category : Technology & Engineering
ISBN : 9780309465182

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Biodefense in the Age of Synthetic Biology by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology Pdf

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Horizontal Gene Transfer

Tomás G. Villa,Miguel Viñas
Horizontal Gene Transfer Book PDF

Author : Tomás G. Villa,Miguel Viñas
Publisher : Springer
Page : 425 pages
File Size : 43,8 Mb
Release : 2019-08-13
Category : Science
ISBN : 9783030218621

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Horizontal Gene Transfer by Tomás G. Villa,Miguel Viñas Pdf

The book focuses on the evolutionary impact of horizontal gene transfer processes on pathogenicity, environmental adaptation and biological speciation. Newly acquired genetic material has been considered as a driving force in evolution for prokaryotic genomes for many years, with recent technical developments advancing this field further. However, the extent and implications of gene transfer between prokaryotes and eukaryotes still raise controversies. This multi-authored volume introduces various means by which DNA can be exchanged, covers gene transfer between prokaryotes and their viruses as well as between bacteria and eukaryotes, such as fungi, plants and animals, and addresses the role of horizontal gene transfer in human diseases. Aspects discussed also include the relevance for virulence and drug resistance development on one hand, and for the occurrence of naturally derived antibiotics and other secondary metabolites on the other hand. This book offers new insights to anyone interested in genome evolution and the exchange of DNA between the different domains of life, the genetic toolkit for adaptation and the emergence of multidrug resistant bacteria.

New and Future Developments in Microbial Biotechnology and Bioengineering

Vijai G. Gupta,Anita Pandey
New and Future Developments in Microbial Biotechnology and Bioengineering Book PDF

Author : Vijai G. Gupta,Anita Pandey
Publisher : Elsevier
Page : 380 pages
File Size : 40,7 Mb
Release : 2019-06-14
Category : Medical
ISBN : 9780444635112

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New and Future Developments in Microbial Biotechnology and Bioengineering by Vijai G. Gupta,Anita Pandey Pdf

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community. Compiles the latest developments in the area of microbial secondary metabolites Authored by the top international researchers in this area Includes information related to nearly all areas of a microbial secondary metabolites system

Biosurfactants for a Sustainable Future

Hemen Sarma,Majeti Narasimha Vara Prasad
Biosurfactants for a Sustainable Future Book PDF

Author : Hemen Sarma,Majeti Narasimha Vara Prasad
Publisher : John Wiley & Sons
Page : 556 pages
File Size : 52,8 Mb
Release : 2021-04-16
Category : Technology & Engineering
ISBN : 9781119671053

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Biosurfactants for a Sustainable Future by Hemen Sarma,Majeti Narasimha Vara Prasad Pdf

Biosurfactants for a Sustainable Future Explore the state-of-the-art in biosurfactant technology and its applications in environmental remediation, biomedicine, and biotechnology Biosurfactants for a Sustainable Future explores recent developments in biosurfactants and their use in a variety of cutting-edge applications. The book opens a window on the rapid development of microbiology by explaining how microbes and their products are used in advanced medical technology and in the sustainable remediation of emerging environmental contaminants. The book emphasizes the different techniques that are used for the production of biosurfactants from microorganisms and their characterization. Various aspects of biosurfactants, including structural characteristics, developments, production, bio-economics and their sustainable use in the environment and biomedicine, are addressed, and the book also presents metagenomic strategies to facilitate the discovery of novel biosurfactants producing microorganisms. Readers will benefit from the inclusion of: A thorough introduction to the state-of-the-art in biosurfactant technology, techniques, and applications An exploration of biosurfactant enhanced remediation of sediments contaminated with organics and inorganics A discussion of perspectives for biomedical and biotechnological applications of biosurfactants A review of the antiviral, antimicrobial, and antibiofilm potential of biosurfactants against multi-drug-resistant pathogens. An examination of biosurfactant-inspired control of methicillin-resistant Staphylococcus aureus Perfect for academic researchers and scientists working in the petrochemical industry, pharmaceutical industry, and in the agroindustry, Biosurfactants for a Sustainable Future will also earn a place in the libraries of scientists working in environmental biotechnology, environmental science, and biomedical engineering.

Developmental Biology in Prokaryotes and Lower Eukaryotes

Tomás González Villa,Trinidad de Miguel Bouzas
Developmental Biology in Prokaryotes and Lower Eukaryotes Book PDF

Author : Tomás González Villa,Trinidad de Miguel Bouzas
Publisher : Springer Nature
Page : 560 pages
File Size : 53,9 Mb
Release : 2021-07-31
Category : Science
ISBN : 9783030775957

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Developmental Biology in Prokaryotes and Lower Eukaryotes by Tomás González Villa,Trinidad de Miguel Bouzas Pdf

‘Developmental biology’ is widely understood as processes, which mainly concern embryonic animal development and differentiation of cells and tissue. It is also often defined as the timeline for the evolutionary developmental biology of eukaryotic multicellular higher organisms, i.e., plants and animals. The development of prokaryotes and lower eukaryotes in contrary has been neglected for a long time, which was the motivation for publishing this book. This book highlights one of Darwin's most important findings: Evolution is a creative, but not a conscious process. It also illustrates that this concept does not only apply to multicellular higher organisms, but affects every form of life. The reader shall find complex biochemical and genetic pathways of bacteria, yeasts or protozoa, comparable to those exhibited by plants or animals. The molecular mechanisms of dramatic genome rearrangements, recombination and horizontal gene transfer that are responsible for evolutionary adaptations are discussed. Additionally, the book covers bacteria of the genera Myxobacteriales and Caulobacterales, which are able to develop tissue-like cellular organization. The morphogenesis of entomopathogenic fungi and the endosymbiont theory are also addressed. The book is a useful introduction to the field for junior scientists, interested in bacteriology, protistology and fungal development. It is also an interesting read for advanced scientists, giving them a broader view of the field beyond their area of specialization.

The Resistance Phenomenon in Microbes and Infectious Disease Vectors

Institute of Medicine,Board on Global Health,Forum on Emerging Infections
The Resistance Phenomenon in Microbes and Infectious Disease Vectors Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 333 pages
File Size : 42,7 Mb
Release : 2003-03-26
Category : Medical
ISBN : 9780309168304

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The Resistance Phenomenon in Microbes and Infectious Disease Vectors by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Microbial Threats to Health

Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century
Microbial Threats to Health Book PDF

Author : Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century
Publisher : National Academies Press
Page : 397 pages
File Size : 53,6 Mb
Release : 2003-08-25
Category : Medical
ISBN : 9780309185547

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Microbial Threats to Health by Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century Pdf

Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.

Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control

Sebastien Gagneux
Strain Variation in the Mycobacterium tuberculosis Complex Its Role in Biology Epidemiology and Control Book PDF

Author : Sebastien Gagneux
Publisher : Springer
Page : 314 pages
File Size : 44,8 Mb
Release : 2017-11-06
Category : Science
ISBN : 9783319643717

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Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control by Sebastien Gagneux Pdf

Until about 10 years ago, the general view in the field was that Mycobacterium tuberculosis, the causative agent of human tuberculosis was a “clone” with insufficient natural sequence variation between clinical strains to be considered biologically and epidemiologically “relevant”. This view has now changed quite dramatically thanks to the –omics revolution, particularly the advent of next generation DNA sequencing. Large-scale comparative genomic studies over the last few years have revealed that M. tuberculosis clinical strains are more genetically diverse than appreciated previously. Moreover, an increasing number of experimental and epidemiological studies are showing that this genetic diversity also translates into important phenotypic variation. Taken together, these findings have led to a paradigm shift, such that currently phylogenetic diversity among M. tuberculosis clinical strains is being considered in the development of new tools to combat tuberculosis. The purpose of this book is to bring together a series of contributions from some of the most influential groups working on various aspects of M. tuberculosis diversity, and which through their work have contributed to the this paradigm shift. This includes authors focusing on the evolution of M. tuberculosis in relation to other members of the M. tuberculosis complex adapted to animals, the co-evolution between M. tuberculosis and humans, the phenotypic consequences of strains diversity both from an experimental and epidemiological point of view, the ecology and evolution of drug resistant tuberculosis, the diversity and evolution of the BCG vaccine strains, and the use of mathematical modelling to study strain diversity and drug resistance in human tuberculosis. No such book has ever been published, and given the paradigm shift described above, this book will be a valuable resource both for established researchers as well as new scientists, clinicians and public health officials joining the growing field of tuberculosis research.

Computer-Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates

Jujjvarapu Satya Eswari,Swasti Dhagat,Manisha Yadav
Computer Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates Book PDF

Author : Jujjvarapu Satya Eswari,Swasti Dhagat,Manisha Yadav
Publisher : CRC Press
Page : 130 pages
File Size : 48,8 Mb
Release : 2019-09-24
Category : Medical
ISBN : 9781351018296

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Computer-Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates by Jujjvarapu Satya Eswari,Swasti Dhagat,Manisha Yadav Pdf

Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques. Key Features: Focuses on the use lipopeptides as new antimicrobial compounds Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and intellectual property rights

A Critical Appraisal of Current Microbiological Hot Topics

T. G. Villa,Ana G. Abril
A Critical Appraisal of Current Microbiological Hot Topics Book PDF

Author : T. G. Villa,Ana G. Abril
Publisher : Cambridge Scholars Publishing
Page : 314 pages
File Size : 46,6 Mb
Release : 2023-05-03
Category : Medical
ISBN : 9781527502482

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A Critical Appraisal of Current Microbiological Hot Topics by T. G. Villa,Ana G. Abril Pdf

This book contains multiple chapters discussing some of the hot topics of Microbiology, including the role of the gut microbiota on allergies, the variety of man-related microbial activities, such as attenuated bacterial strains and vaccines, diseases and several syndromes conducting to obesity, as well as how microbiology can help in oil prospection and how this offers many opportunities for microbiologists. This text is for students of Microbiology, microbiologists themselves, and is written in a way that anyone less familiar with the field, but still interested in the topics it explores, can access the information in this book.

Implication of Quorum Sensing System in Biofilm Formation and Virulence

Pallaval Veera Bramhachari
Implication of Quorum Sensing System in Biofilm Formation and Virulence Book PDF

Author : Pallaval Veera Bramhachari
Publisher : Springer
Page : 381 pages
File Size : 50,7 Mb
Release : 2019-01-28
Category : Medical
ISBN : 9789811324291

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Implication of Quorum Sensing System in Biofilm Formation and Virulence by Pallaval Veera Bramhachari Pdf

This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.

Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers

Pallaval Veera Bramhachari,Nageswara Rao Reddy Neelapu
Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers Book PDF

Author : Pallaval Veera Bramhachari,Nageswara Rao Reddy Neelapu
Publisher : Springer Nature
Page : 238 pages
File Size : 49,6 Mb
Release : 2020-07-21
Category : Medical
ISBN : 9789811544316

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Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers by Pallaval Veera Bramhachari,Nageswara Rao Reddy Neelapu Pdf

This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic biology devices, and 'omics' technologies for the early diagnosis of gastrointestinal cancer. In addition it examines the potential of genome-wide association studies, big data analytics, computation biology, systems biology, and nanotechnology for early diagnostics and therapeutics for gastrointestinal cancer, with a focus on personalized cancer treatment. The book is a valuable source for researchers and clinicians engaged in detection and diagnosis of gastrointestinal cancers.