Nmr Case Studies

Nmr Case Studies Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Nmr Case Studies book. This book definitely worth reading, it is an incredibly well-written.

NMR Case Studies

Jeffrey H Simpson
NMR Case Studies Book PDF

Author : Jeffrey H Simpson
Publisher : Elsevier
Page : 234 pages
File Size : 47,6 Mb
Release : 2017-09-19
Category : Science
ISBN : 9780128033531

Get Book

NMR Case Studies by Jeffrey H Simpson Pdf

NMR Case Studies: Data Analysis of Complicated Molecules provides a detailed discussion of the full logical flow associated with assigning the NMR spectra of complex molecules, also helping readers further develop their NMR spectral assignment skills. The robust case studies present the logic of each assignment, from beginning to end, fully exploring the available range of potential solutions. Readers will gain a better appreciation of various approaches and develop an intuitive sense for when this particular concept should be implemented, thus enhancing their skillsets and providing a host of methodologies potentially amenable to yielding correct assignments. Authored by a scientist with more than 20 years of experience in research and instruction, this book is the ideal reference for anyone in search of application-based content. The book addresses complicated molecules, including corticosteroids, biomolecules, polypeptides, and secondary metabolites. Features the nuclear magnetic resonance (NMR) spectra of a number of large and interesting molecules, ranging from corticosteroids, to secondary metabolites and large synthetically prepared molecules Uses case studies to pair the spectral signals from the various sites of each molecule to their molecular counterparts in a process called assignment Includes complex NMR problems, aiding readers in the development of NMR spectral assignment skills Features input from a leading scientist with over 20 years of research and instruction experience in the field

Modern NMR Approaches to the Structure Elucidation of Natural Products

Antony Williams,Gary Martin,David Rovnyak
Modern NMR Approaches to the Structure Elucidation of Natural Products Book PDF

Author : Antony Williams,Gary Martin,David Rovnyak
Publisher : Royal Society of Chemistry
Page : 532 pages
File Size : 45,9 Mb
Release : 2016-12-14
Category : Science
ISBN : 9781849733939

Get Book

Modern NMR Approaches to the Structure Elucidation of Natural Products by Antony Williams,Gary Martin,David Rovnyak Pdf

The Ghanian plant Cryptolepis sanguinolenta is the source of a series of fascinating indoloquinoline alkaloids. The most unusual member of this alkaloid series was initially proposed to be a spiro nonacyclic structure, named cryptospirolepine, and was elucidated in 1993 based on the technologies available at that time. There were, however, several annoying attributes to the structure that bothered analysts for the ensuing 22 years. During the two decades that followed the initial work there have been enormous developments in NMR technology. Using new experimental approaches, specifically homodecoupled 1,1- and 1,n-HD-ADEQUATE NMR experiments developed in 2014, the structure of only a 700 µg sample of cryptospirolepine has been revised and is shown on the cover of this volume. The confluence of the NMR technological and methodological advances that allowed the revision of the structure of cryptospirolepine using a submilligram sample seems a fitting example for this book, which is dedicated to the NMR characterization of various classes of natural products. Volume 2 considers data processing and algorithmic based analyses tailored to natural product structure elucidation and reviews the application of NMR to the analysis of a series of different natural product families including marine natural products, terpenes, steroids, alkaloids and carbohydrates. Volume 1 discusses contemporary NMR approaches including optimized and future hardware and experimental approaches to obtain both the highest quality and most appropriate spectral data for analysis. These books, bringing together acknowledged experts, uniquely focus on the combination of experimental approaches and modern hardware and software applied to the structure elucidation of natural products. The volumes will be an essential resource for NMR spectroscopists, natural product chemists and industrial researchers working on natural product analysis or the characterization of impurities and degradation products of pharmaceuticals that can be as scarce as natural product samples.

Case Studies in Superconducting Magnets

Yukikazu Iwasa
Case Studies in Superconducting Magnets Book PDF

Author : Yukikazu Iwasa
Publisher : Springer Science & Business Media
Page : 717 pages
File Size : 41,8 Mb
Release : 2009-04-05
Category : Technology & Engineering
ISBN : 9780387098005

Get Book

Case Studies in Superconducting Magnets by Yukikazu Iwasa Pdf

The 2nd edition emphasizes two areas not emphasized in the 1st edition: 1) high-temperature superconductor (HTS) magnets; 2) NMR (nuclear magnetic resonance) and MRI (magnetic resonance imaging) magnets. Despite nearly 40 years of R and D on superconducting magnet technology, most areas, notably fusion and electric power applications, are still in the R and D stage. One exception is in the area of NMR and MRI. NMR magnets are very popular among chemists, biologists, genome scientists, and most of all, by drug manufacturers for drug discovery and development. MRI and NMR magnets have become the most successful application of superconducting magnet technology and this trend should continue. The 2nd edition will have new materials never treated formally in any other book of this kind. As with the 1st, most subjects will be presented through problem format to educate and train the designer.

Structure-activity Relationship Studies in Drug Development by NMR Spectroscopy

Atta-ur- Rahman,M. Iqbal Choudhary
Structure activity Relationship Studies in Drug Development by NMR Spectroscopy Book PDF

Author : Atta-ur- Rahman,M. Iqbal Choudhary
Publisher : Bentham Science Publishers
Page : 221 pages
File Size : 42,6 Mb
Release : 2011
Category : Science
ISBN : 9781608051649

Get Book

Structure-activity Relationship Studies in Drug Development by NMR Spectroscopy by Atta-ur- Rahman,M. Iqbal Choudhary Pdf

"NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parame"

Annual Reports on NMR Spectroscopy

Anonim
Annual Reports on NMR Spectroscopy Book PDF

Author : Anonim
Publisher : Academic Press
Page : 378 pages
File Size : 42,7 Mb
Release : 2020-04-29
Category : Science
ISBN : 9780128209738

Get Book

Annual Reports on NMR Spectroscopy by Anonim Pdf

Annual Reports on NMR Spectroscopy, Volume 100, is a premier resource for both specialists and non-specialists who are looking to become familiar with new techniques and applications in NMR spectroscopy. Chapters in this new release cover In Operando NMR Studies, Recent Developments in Automotive Differential Analysis of NMR Results, Applications of SIMPSON to NMR Studies of Peptides and Proteins, Recent Developments in NMR Line Shape Analysis, and more. Serves as the premier resource for learning the new techniques and applications of NMR spectroscopy Provides a key reference for chemists and physicists using NMR spectroscopy to study the structure and dynamics of molecules Covers all aspects of molecular science, including MRI (Magnetic Resonance Imaging)

Experimental Approaches of NMR Spectroscopy

The Nuclear Magnetic Resonance Society of Japan
Experimental Approaches of NMR Spectroscopy Book PDF

Author : The Nuclear Magnetic Resonance Society of Japan
Publisher : Springer
Page : 636 pages
File Size : 49,5 Mb
Release : 2017-11-23
Category : Science
ISBN : 9789811059667

Get Book

Experimental Approaches of NMR Spectroscopy by The Nuclear Magnetic Resonance Society of Japan Pdf

This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

NMR and MRI of Electrochemical Energy Storage Materials and Devices

Yong Yang,Riqiang Fu,Hua Huo
NMR and MRI of Electrochemical Energy Storage Materials and Devices Book PDF

Author : Yong Yang,Riqiang Fu,Hua Huo
Publisher : Royal Society of Chemistry
Page : 573 pages
File Size : 49,8 Mb
Release : 2021-06-17
Category : Science
ISBN : 9781839160103

Get Book

NMR and MRI of Electrochemical Energy Storage Materials and Devices by Yong Yang,Riqiang Fu,Hua Huo Pdf

Energy storage material is a hot topic in material science and chemistry. During the past decade, nuclear magnetic resonance (NMR) has emerged as a powerful tool to aid understanding of the working and failing mechanisms of energy storage materials and devices. The aim of this book is to introduce the use of NMR methods for investigating electrochemical storage materials and devices. Presenting a comprehensive overview of NMR spectroscopy and magnetic resonance imaging (MRI) on energy storage materials, the book will include the theory of paramagnetic interactions and relevant calculation methods, a number of specific NMR approaches developed in the past decade for battery materials (e.g. in situ, ex situ NMR, MRI, DNP, 2D NMR, NMR dynamics) and case studies on a variety of related materials. Helping both NMR spectroscopists entering the field of batteries and battery specialists seeking diagnostic methods for material and device degradation, it is written by leading authorities from international research groups in this field.

Nuclear Magnetic Resonance

Vasudevan Ramesh
Nuclear Magnetic Resonance Book PDF

Author : Vasudevan Ramesh
Publisher : Royal Society of Chemistry
Page : 326 pages
File Size : 41,6 Mb
Release : 2016-04-28
Category : Nuclear magnetic resonance
ISBN : 9781782620532

Get Book

Nuclear Magnetic Resonance by Vasudevan Ramesh Pdf

This volume will focus on a theme - NMR applications in industry and providing a comprehensive yet critical review of the current literature from various industries.

Modern NMR Techniques for Synthetic Chemistry

Julie Fisher
Modern NMR Techniques for Synthetic Chemistry Book PDF

Author : Julie Fisher
Publisher : CRC Press
Page : 364 pages
File Size : 41,9 Mb
Release : 2014-10-13
Category : Science
ISBN : 9781466592247

Get Book

Modern NMR Techniques for Synthetic Chemistry by Julie Fisher Pdf

A blend of theory and practical advice, Modern NMR Techniques for Synthetic Chemistry illustrates how NMR spectroscopy can be used to determine the abundance, size, shape, and function of organic molecules. It provides you with a description the NMR technique used (more pictorial than mathematical), indicating the most common pulse sequences, some practical information as appropriate, followed by illustrative examples. This format is followed for each chapter so you can skip the more theoretical details if the practical aspects are what interest you. Following a discussion of basic parameters, the book describes the utility of NMR in detecting and quantifying dynamic processes, with particular emphasis on the usefulness of saturation-transfer (STD) techniques. It details pulsed–field gradient approaches to diffusion measurement, diffusion models, and approaches to ‘inorganic’ nuclei detection, important as many synthetic pathways to new organics involve heavier elements. The text concludes with coverage of applications of NMR to the analysis of complex mixtures, natural products, carbohydrates, and nucleic acids—all areas of activity for researchers working at the chemistry-life sciences interface. The book’s unique format provides some theoretical insight into the NMR technique used, indicating the most common pulse sequences. The book draws upon several NMR methods that are resurging or currently hot in the field and indicates the specific pulse sequence used by various spectrometer manufacturers for each technique. It examines the analysis of complex mixtures, a feature not found in most books on this topic.

Annual Reports on NMR Spectroscopy

Graham A. Webb
Annual Reports on NMR Spectroscopy Book PDF

Author : Graham A. Webb
Publisher : Elsevier
Page : 236 pages
File Size : 43,5 Mb
Release : 2007-10-11
Category : Science
ISBN : 0080551947

Get Book

Annual Reports on NMR Spectroscopy by Graham A. Webb Pdf

Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science when precise structural determination is required and when the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy. Provides updates on the latest developments in NMR spectroscopy Includes comprehensive review articles Highlights the increasing importance of NMR spectroscopy as a technique for structural determination

Diffusion and Electrophoretic NMR

Peter Stilbs
Diffusion and Electrophoretic NMR Book PDF

Author : Peter Stilbs
Publisher : Walter de Gruyter GmbH & Co KG
Page : 462 pages
File Size : 55,5 Mb
Release : 2019-08-19
Category : Technology & Engineering
ISBN : 9783110551655

Get Book

Diffusion and Electrophoretic NMR by Peter Stilbs Pdf

Diffusion and Eletrophoretic NMR experiments resolve chemical compounds based on their molecular motion. This publication introduces the basics of these methods and explains how they can be used to measure the size of molecules and aggregates, to determine degree of polymerization and to solve other chemical problems. Supplied with many case studies, the book is a must-have for students and researchers who work with practical NMR measurements.

Handbook of Analysis of Oligonucleotides and Related Products

Jose V. Bonilla,G. Susan Srivatsa
Handbook of Analysis of Oligonucleotides and Related Products Book PDF

Author : Jose V. Bonilla,G. Susan Srivatsa
Publisher : CRC Press
Page : 514 pages
File Size : 51,9 Mb
Release : 2011-02-23
Category : Medical
ISBN : 9781439819937

Get Book

Handbook of Analysis of Oligonucleotides and Related Products by Jose V. Bonilla,G. Susan Srivatsa Pdf

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.

High Resolution NMR Spectroscopy: Understanding Molecules and their Electronic Structures

Anonim
High Resolution NMR Spectroscopy Understanding Molecules and their Electronic Structures Book PDF

Author : Anonim
Publisher : Newnes
Page : 456 pages
File Size : 55,5 Mb
Release : 2013-06-08
Category : Science
ISBN : 9780444594143

Get Book

High Resolution NMR Spectroscopy: Understanding Molecules and their Electronic Structures by Anonim Pdf

The progress in nuclear magnetic resonance (NMR) spectroscopy that took place during the last several decades is observed in both experimental capabilities and theoretical approaches to study the spectral parameters. The scope of NMR spectroscopy for studying a large series of molecular problems has notably broadened. However, at the same time, it requires specialists to fully use its potentialities. This is a notorious problem and it is reflected in the current literature where this spectroscopy is typically only used in a routine way. Also, it is seldom used in several disciplines in which it could be a powerful tool to study many problems. The main aim of this book is to try to help reverse these trends. This book is divided in three parts dealing with 1) high-resolution NMR parameters; 2) methods for understanding high-resolution NMR parameters; and 3) some experimental aspects of high-resolution NMR parameters for studying molecular structures. Each part is divided into chapters written by different specialists who use different methodologies in their work. In turn, each chapter is divided into sections. Some features of the different sections are highlighted: it is expected that part of the readership will be interested only in the basic aspects of some chapters, while other readers will be interested in deepening their understanding of the subject dealt with in them. Shows how NMR parameters are useful for structure assignment as well as to obtain insight on electronic structures Emphasis on conceptual aspects Contributions by specialists who use the discussed methodologies in their everyday work

Intrinsically Disordered Proteins Studied by NMR Spectroscopy

Isabella C. Felli,Roberta Pierattelli
Intrinsically Disordered Proteins Studied by NMR Spectroscopy Book PDF

Author : Isabella C. Felli,Roberta Pierattelli
Publisher : Springer
Page : 421 pages
File Size : 40,9 Mb
Release : 2015-09-19
Category : Science
ISBN : 9783319201641

Get Book

Intrinsically Disordered Proteins Studied by NMR Spectroscopy by Isabella C. Felli,Roberta Pierattelli Pdf

This book discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). The properties of IDPs and IDPRs are highly complementary to those deriving from the presence of a unique and well-defined three-dimensional fold. Ignored for a long time in high-resolution studies of proteins, intrinsic protein disorder is now recognized as one of the key features for a large variety of cellular functions, where structural flexibility presents a functional advantage in terms of binding plasticity and promiscuity and this volume explores this exciting new research. Recent progress in the field has radically changed our perspective to study IDPs through NMR: increasingly complex IDPs can now be characterized, a wide range of observables can be determined reporting on the structural and dynamic properties, computational methods to describe the structure and dynamics are in continuous development and IDPs can be studied in environments as complex as whole cells. This volume communicates the new exciting possibilities offered by NMR and presents open questions to foster further developments. Intrinsically Disordered Proteins Studied by NMR Spectroscopy provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.

Nuclear Magnetic Resonance 49

Josep Sauri,Paul Hodgkinson
Nuclear Magnetic Resonance 49 Book PDF

Author : Josep Sauri,Paul Hodgkinson
Publisher : Royal Society of Chemistry
Page : 276 pages
File Size : 55,6 Mb
Release : 2023-11-29
Category : Science
ISBN : 9781837671908

Get Book

Nuclear Magnetic Resonance 49 by Josep Sauri,Paul Hodgkinson Pdf

Applications of nuclear magnetic resonance span a wide range of scientific disciplines, from chemistry and physics to medicine. For those wanting to become acquainted with NMR or seasoned practitioners, this is a valuable source of current methods and applications.