Nmr In Glycoscience And Glycotechnology

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NMR in Glycoscience and Glycotechnology

Author : Koichi Kato,Thomas Peters
Publisher : Royal Society of Chemistry
Page : 417 pages
File Size : 48,6 Mb
Release : 2017-05-17
Category : Science
ISBN : 9781782623106

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NMR in Glycoscience and Glycotechnology by Koichi Kato,Thomas Peters Pdf

This volume focuses on solution and solid-state NMR of carbohydrates, glycoproteins, glyco-technologies, biomass and related topics. It is estimated that at least 80% of all proteins are glycoproteins. Because of the complexity, heterogeneity and flexibility of the sugar chains, the structural biology approaches for glycoconjugates have been generally avoided. NMR techniques although well established for structural analyses of proteins and nucleic acids, cannot be simply applied to this complex class of biomolecules. Nonetheless, recently developed NMR techniques for carbohydrates open the door to conformational studies of a variety of sugar chains of biological interest. NMR studies on glycans will have significant impact on the development of vaccines, adjuvants, therapeutics, biomarkers and on biomass regeneration. In this volume, the Editors have collected the most up-to-date NMR applications from experts in the field of carbohydrate NMR spectroscopy. Timely and useful, not only for NMR specialists, it will appeal to researchers in the general field of structural biology, biochemistry and biophysics, molecular and cellular biology and material science.

Experimental Approaches of NMR Spectroscopy

Author : The Nuclear Magnetic Resonance Society of Japan
Publisher : Springer
Page : 636 pages
File Size : 43,6 Mb
Release : 2017-11-23
Category : Science
ISBN : 9789811059667

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Experimental Approaches of NMR Spectroscopy by The Nuclear Magnetic Resonance Society of Japan Pdf

This book describes the advanced developments in methodology and applications of NMR spectroscopy to life science and materials science. Experts who are leaders in the development of new methods and applications of life and material sciences have contributed an exciting range of topics that cover recent advances in structural determination of biological and material molecules, dynamic aspects of biological and material molecules, and development of novel NMR techniques, including resolution and sensitivity enhancement. First, this book particularly emphasizes the experimental details for new researchers to use NMR spectroscopy and pick up the potentials of NMR spectroscopy. Second, the book is designed for those who are involved in either developing the technique or expanding the NMR application fields by applying them to specific samples. Third, the Nuclear Magnetic Resonance Society of Japan has organized this book not only for NMR members of Japan but also for readers worldwide who are interested in using NMR spectroscopy extensively.

Glycobiology of the Nervous System

Author : Cara-Lynne Schengrund,Robert K. Yu
Publisher : Springer Nature
Page : 506 pages
File Size : 41,7 Mb
Release : 2022-10-18
Category : Medical
ISBN : 9783031123900

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Glycobiology of the Nervous System by Cara-Lynne Schengrund,Robert K. Yu Pdf

This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.

Fast 2D Solution-state NMR

Author : Jean-Nicolas Dumez,Patrick Giraudeau
Publisher : Royal Society of Chemistry
Page : 560 pages
File Size : 48,9 Mb
Release : 2023-05-17
Category : Science
ISBN : 9781839168079

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Fast 2D Solution-state NMR by Jean-Nicolas Dumez,Patrick Giraudeau Pdf

Written by active investigators in the field, this book describes state-of-the-art methods that can accelerate the acquisition of 2D NMR spectra in solution-state NMR. The acquisition of fast multi-dimensional NMR data has motivated numerous ground-breaking developments in NMR pulse sequences and associated data processing methods. These in turn have revolutionized the way 2D NMR acquisitions are performed, at the same time broadening the scope of applications of 2D NMR. The first part of the book provides an in-depth description of the concepts and implementation of major fast 2D NMR methods. The second part follows with illustrations of how such methods can be used in applications that require the acquisition of fast 2D NMR spectra, from reaction monitoring to hyperpolarization, including applications to a broad variety of samples and experimental conditions. Appealing to readers from both the methodology and applications communities, this title will fill a gap in the market for a book focused on small molecule NMR, and researchers from both academia and industry will find a rich plethora of knowledge.

NMR and MRI of Gels

Author : Yves De Deene
Publisher : Royal Society of Chemistry
Page : 409 pages
File Size : 54,5 Mb
Release : 2020-07-07
Category : Science
ISBN : 9781788019200

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NMR and MRI of Gels by Yves De Deene Pdf

Gels are used in a large variety of commercial and scientific products from drug delivery systems and food science to biomedical sensors. They also are invaluable in MRI physics research where they mimic biological tissue and in radiotherapy quality assurance where they are used to capture the three dimensional radiation dose distribution. This unique book discusses the state-of-the-art of NMR and MRI techniques in studying the physics and chemistry of gel systems, in their application as MRI phantoms and as three dimensional radiation dosimeters. The first part of the book will cover the fundamental physical concepts of gels and the NMR techniques to study gel systems. The second part is dedicated to the application of gels in the life sciences and in the medical practice to validate radiotherapy and new MRI techniques. Filling the gap in literature, this volume provides the scientific reader with an extensive overview of possible techniques and methods to study the interesting properties and applications of gels. For the MRI researcher and medical physicist, the book will be a valuable resource in using gel phantoms for validating contemporary MRI techniques and radiotherapy treatments.

In-cell NMR Spectroscopy

Author : Yutaka Ito,Volker Dötsch,Masahiro Shirakawa
Publisher : Royal Society of Chemistry
Page : 322 pages
File Size : 44,8 Mb
Release : 2019-12-09
Category : Science
ISBN : 9781839160936

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In-cell NMR Spectroscopy by Yutaka Ito,Volker Dötsch,Masahiro Shirakawa Pdf

In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.

Field-cycling NMR Relaxometry

Author : Rainer Kimmich
Publisher : Royal Society of Chemistry
Page : 590 pages
File Size : 47,8 Mb
Release : 2018-10-11
Category : Science
ISBN : 9781788015509

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Field-cycling NMR Relaxometry by Rainer Kimmich Pdf

Field-cycling NMR relaxometry is evolving into a methodology of widespread interest with recent technological developments resulting in powerful and versatile commercial instruments. Polymers, liquid crystals, biomaterials, porous media, tissue, cement and many other materials of practical importance can be studied using this technique. This book summarises the expertise of leading scientists in the area and the editor is well placed, after four decades of working in this field, to ensure a broad ranging and high quality title. Starting with an overview of the basic principles of the technique and the scope of its use, the content then develops to look at theory, instrumentation, practical limitations and applications in different systems. Newcomers to the field will find this book invaluable for successful use of the technique. Researchers already in academic and industrial settings, interested in molecular dynamics and magnetic resonance, will discover an important addition to the literature.

NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces

Author : Anirban Bhunia,Hanudatta S Atreya,Neeraj Sinha
Publisher : Royal Society of Chemistry
Page : 733 pages
File Size : 44,6 Mb
Release : 2022-08-17
Category : Science
ISBN : 9781839162091

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NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces by Anirban Bhunia,Hanudatta S Atreya,Neeraj Sinha Pdf

Providing a comprehensive amalgamation of the scattered knowledge of how to apply high-resolution NMR techniques to biomolecular systems, this book will break down the conventional stereotypes in the use of NMR for structural studies.

NMR-based Metabolomics

Author : Hector C Keun
Publisher : Royal Society of Chemistry
Page : 384 pages
File Size : 41,7 Mb
Release : 2018-01-04
Category : Science
ISBN : 9781788013970

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NMR-based Metabolomics by Hector C Keun Pdf

In the rapidly growing field of metabolomics, a comprehensive book describing the state of the art in the application of NMR spectroscopy will be a key title for practitioners. Providing a unique resource of background knowledge, resources, instrumental platforms and software, this book will introduce relevant theory to the researcher as well as serve as a practical guide detailing key experiments and data handling procedures. Information available on common sample types will be described together with reference to the latest web-based resources available. Application-specific considerations will be discussed for a wide range of research topics. Written by an expert team as a service to the metabolomics community, this book will appeal to NMR spectroscopists, analytical chemists and biochemists especially those with an interest in medical applications.

Paramagnetism in Experimental Biomolecular NMR

Author : Claudio Luchinat,Giacomo Parigi,Enrico Ravera
Publisher : Royal Society of Chemistry
Page : 340 pages
File Size : 40,5 Mb
Release : 2018-08-03
Category : Science
ISBN : 9781788014960

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Paramagnetism in Experimental Biomolecular NMR by Claudio Luchinat,Giacomo Parigi,Enrico Ravera Pdf

Paramagnetic NMR is a growing technique that represents an increasingly important tool for the investigation of biomolecules. This book presents an update and overview of the paramagnetic NMR phenomena and effects as well as guidelines for practical implementation of state-of-the-art experiments. All experiments are supported by a solid theoretical foundation. Areas mentioned are the development of solid state NMR, the use of paramagnetic tags providing information on the structure and mobility of the investigated systems, and dynamic nuclear polarization to increase sensitivity. Compiled by experts in the field, this book has international appeal for researchers as well as students interested in magnetic resonance and structural biology who require experimental support and accessible information.

NMR and MRI of Electrochemical Energy Storage Materials and Devices

Author : Yong Yang,Riqiang Fu,Hua Huo
Publisher : Royal Society of Chemistry
Page : 573 pages
File Size : 55,9 Mb
Release : 2021-06-21
Category : Science
ISBN : 9781788018487

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NMR and MRI of Electrochemical Energy Storage Materials and Devices by Yong Yang,Riqiang Fu,Hua Huo Pdf

The aim of this book is to introduce the use of NMR and MRI methods for investigating electrochemical storage materials and devices to help both NMR spectroscopists entering the field of batteries and battery specialists seeking diagnostic methods for material and device degradation.

Optimizing NMR Methods for Structure Elucidation

Author : Darcy C. Burns,William F. Reynolds
Publisher : Royal Society of Chemistry
Page : 238 pages
File Size : 42,9 Mb
Release : 2018-09-26
Category : Science
ISBN : 9781782625391

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Optimizing NMR Methods for Structure Elucidation by Darcy C. Burns,William F. Reynolds Pdf

This book is aimed at informing organic chemists and natural products chemists on the use of NMR for structure elucidation to enable them to ensure they yield the most reliable possible data in the minimum possible time. It covers the latest pulse sequences, acquisition and processing methods, practical areas not covered in most texts e.g. detailed consideration of the relative advantages and disadvantages of different pulse sequences, choosing acquisition and processing parameters to get the best possible data in the least possible time, pitfalls to avoid and how to minimize the risks of getting wrong structures. Useful in industrial, pharma or research environments, this reference book is for anyone involved with organic chemistry research and, in particular, natural products research requiring advice for getting the best results from the NMR facilities.

NMR Methods for Characterization of Synthetic and Natural Polymers

Author : Rongchun Zhang,Toshikazu Miyoshi,Pingchuan Sun
Publisher : Royal Society of Chemistry
Page : 590 pages
File Size : 44,6 Mb
Release : 2019-07-29
Category : Science
ISBN : 9781788018630

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NMR Methods for Characterization of Synthetic and Natural Polymers by Rongchun Zhang,Toshikazu Miyoshi,Pingchuan Sun Pdf

Since the introduction of FT-NMR spectroscopy around five decades ago, NMR has achieved significant advances in hardware and methodologies, accompanied with the enhancement of spectral resolution and signal sensitivity. Rapid developments in the polymers field mean that accurate and quantitative characterization of polymer structures and dynamics is the keystone for precisely regulating and controlling the physical and chemical properties of the polymer. This book specifically focuses on NMR investigation of complex polymers for the polymer community as well as NMR spectroscopists, and will push the development of both fields. It covers the latest advances, for example high field DNP and ultrafast MAS methodologies, and show how these novel NMR methods characterize various synthetic and natural polymers.

Modern Methods in Solid-state NMR

Author : Paul Hodgkinson
Publisher : Royal Society of Chemistry
Page : 452 pages
File Size : 41,5 Mb
Release : 2018-04-09
Category : Science
ISBN : 9781782628545

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Modern Methods in Solid-state NMR by Paul Hodgkinson Pdf

Solid-state NMR covers an enormous range of material types and experimental techniques. Although the basic instrumentation and techniques of solids NMR are readily accessible, there can be significant barriers, even for existing experts, to exploring the bewildering array of more sophisticated techniques. In this unique volume, a range of experts in different areas of modern solid-state NMR explain about their area of expertise, emphasising the “practical aspects” of implementing different techniques, and illustrating what questions can and cannot be addressed. Later chapters address complex materials, showing how different NMR techniques discussed in earlier chapters can be brought together to characterise important materials types. The volume as a whole focusses on topics relevant to the developing field of “NMR crystallography” – the use of solids NMR as a complement to diffraction crystallography. This book is an ideal complement to existing introductory texts and reviews on solid-state NMR. New researchers wanting to understand new areas of solid-state NMR will find each chapter to be the equivalent to spending time in the laboratory of an internationally leading expert, learning the hints and tips that make the difference between knowing about a technique and being ready to put it into action. With no equivalent on the market, it will be of interest to every solid-state NMR researcher (academic and postgraduate) working in the chemical sciences.

Fast NMR Data Acquisition

Author : Mehdi Mobli,Jeffrey C Hoch
Publisher : Royal Society of Chemistry
Page : 308 pages
File Size : 40,9 Mb
Release : 2017-05-18
Category : Science
ISBN : 9781782628361

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Fast NMR Data Acquisition by Mehdi Mobli,Jeffrey C Hoch Pdf

Providing a definitive reference source on novel methods in NMR acquisition and processing, this book will highlight similarities and differences between emerging approaches and focus on identifying which methods are best suited for different applications. The highly qualified editors have conducted extensive research into the fundamentals of fast methods of data acquisition in NMR, including applications of non-Fourier methods of spectrum analysis. With contributions from additional distinguished experts in allied fields, clear explanations are provided on methods that speed up NMR experiments using different ways to manipulate the nuclei in the sample, modern methods for estimating the spectrum from the time domain response recorded during an NMR experiment, and finally how the data is sampled. Starting with a historical overview of Fourier Transformation and its role in modern NMR spectroscopy, this volume will clarify and demystify this important emerging field for spectroscopists and analytical chemists in industry and academia.