Novel Approaches And Strategies For Biologics Vaccines And Cancer Therapies

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Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies

Manmohan Singh,Maya Salnikova
Novel Approaches and Strategies for Biologics Vaccines and Cancer Therapies Book PDF

Author : Manmohan Singh,Maya Salnikova
Publisher : Academic Press
Page : 520 pages
File Size : 49,5 Mb
Release : 2014-12-30
Category : Medical
ISBN : 9780124166615

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Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies by Manmohan Singh,Maya Salnikova Pdf

Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad community of scientists, students and clinicians. Written by leading authors across academia and industry, this book covers important topics such as unique drug delivery devices, non-parenteral delivery trends, novel approaches to the treatment of cancer, immunotherapy and more. It includes real-world cases and examples which highlight formulations with therapeutic proteins, monoclonal antibodies, peptides and biobetters, as well as cases on novel vaccines formulations including evolving pathogens, novel modalities of vaccines, universal vaccines. This book is a thorough and useful resource on the development of novel biologics, vaccines and cancer therapies. Provides strategies for the development of safe and efficacious novel formulations for various modalities of biologics, vaccines and for cancer therapy Highlights novel cases from current clinical trials as well as marketed products Reviews overall successes and challenges in the development of novel formulations, including new molecular targets for the treatment of diseases, design of target-specific therapies, regulatory considerations, individualized therapies

Handbook of Cancer Vaccines

Michael A. Morse,Timothy M. Clay,H. Kim Lyerly
Handbook of Cancer Vaccines Book PDF

Author : Michael A. Morse,Timothy M. Clay,H. Kim Lyerly
Publisher : Humana Press
Page : 592 pages
File Size : 49,7 Mb
Release : 2004-01-28
Category : Medical
ISBN : 1588292096

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Handbook of Cancer Vaccines by Michael A. Morse,Timothy M. Clay,H. Kim Lyerly Pdf

An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents

Manju Rawat Singh,Deependra Singh,Jagat Kanwar,Nagendra Singh Chauhan
Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents Book PDF

Author : Manju Rawat Singh,Deependra Singh,Jagat Kanwar,Nagendra Singh Chauhan
Publisher : Academic Press
Page : 657 pages
File Size : 46,6 Mb
Release : 2020-04-07
Category : Business & Economics
ISBN : 9780128199183

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Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents by Manju Rawat Singh,Deependra Singh,Jagat Kanwar,Nagendra Singh Chauhan Pdf

Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents provides sound data on the utility of biological and plant-based drugs and describes challenges faced in all aspects offering indispensable strategies to use in the development of bioactive medicines. Bioactive based medications are commonly used throughout the world and have been recognized by physicians and patients for their therapeutic efficacy. Bioactive formulations, including their subordinates and analogs, address 50% of all medicines in clinical practice. Novel bioactive medicine transporters can cure many disorders by both spatial and transitory approaches and have various justifications in medicinal potential. This book presents information on the utility of natural, plant, animal and bioengineered bioactive materials. It is a fundamental source of information and data for pharmacognosists, pharmaceutical analysts, drug transport scientists and pharmacologists working in bioactive medications. Advances information on various bioactive based medications, their sources, clinical consequences and transport strategies Illustrates diverse transport systems for bioactives and derivatives, novel techniques for formulations, targeting strategies and fundamental qualities of developed bioactive carriers, and their safety concerns and standardization Discusses distinctive transport systems, stability, upgraded dissolvability, and enhanced bioavailability of bioactives

Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases

Dinesh Kumar Chellappan,Kavita Pabreja,Md. Faiyazuddin
Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases Book PDF

Author : Dinesh Kumar Chellappan,Kavita Pabreja,Md. Faiyazuddin
Publisher : Springer Nature
Page : 652 pages
File Size : 52,6 Mb
Release : 2022-03-23
Category : Medical
ISBN : 9789811643927

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Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases by Dinesh Kumar Chellappan,Kavita Pabreja,Md. Faiyazuddin Pdf

This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.

Rare Diseases and Orphan Products

Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
Rare Diseases and Orphan Products Book PDF

Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development
Publisher : National Academies Press
Page : 442 pages
File Size : 47,9 Mb
Release : 2011-04-03
Category : Medical
ISBN : 9780309158060

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Rare Diseases and Orphan Products by Institute of Medicine,Board on Health Sciences Policy,Committee on Accelerating Rare Diseases Research and Orphan Product Development Pdf

Rare diseases collectively affect millions of Americans of all ages, but developing drugs and medical devices to prevent, diagnose, and treat these conditions is challenging. The Institute of Medicine (IOM) recommends implementing an integrated national strategy to promote rare diseases research and product development.

Nanomedicine-Based Approaches for the Treatment of Dementia

Umesh Gupta,Prashant Kesharwani
Nanomedicine Based Approaches for the Treatment of Dementia Book PDF

Author : Umesh Gupta,Prashant Kesharwani
Publisher : Academic Press
Page : 320 pages
File Size : 53,8 Mb
Release : 2022-10-11
Category : Medical
ISBN : 9780323859066

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Nanomedicine-Based Approaches for the Treatment of Dementia by Umesh Gupta,Prashant Kesharwani Pdf

Nanomedicine-Based Approaches for the Treatment of Dementia explores a wide range of promising approaches for the diagnosis and treatment of dementia. The book begins with introductory sections on dementia and brain ailments that are followed by further chapters that discuss detailed information about challenges of drug delivery across the blood-brain barrier as well as the current status. This book helps readers design and develop novel drug delivery systems and devices for the treatment of dementia that take advantage of recent advances in nanomedical technologies. Numerous drug delivery systems have been developed recently for dementia. Unfortunately, most of them are ineffective since dementia is not a single disease. It is an umbrella term for several neurodegenerative conditions which alter brain functions. Due to this, there is an urgent need for innovative technologies/nano drug delivery systems to improve the targeting and delivery of therapeutic as well as diagnostic agents specifically for treating dementia. Explores promising approaches for the diagnosis and treatment of dementia Discusses advances in cutting-edge nanomedical technologies Focuses on the design, synthesis and application of nanocarriers in drug delivery

Natural Immunomodulators: Promising Therapy for Disease Management

Vandana S. Nikam
Natural Immunomodulators Promising Therapy for Disease Management Book PDF

Author : Vandana S. Nikam
Publisher : Bentham Science Publishers
Page : 441 pages
File Size : 42,6 Mb
Release : 2023-05-16
Category : Medical
ISBN : 9789815123265

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Natural Immunomodulators: Promising Therapy for Disease Management by Vandana S. Nikam Pdf

Natural Immunomodulators: Promising Therapy for Disease Management discusses the use of natural immunomodulators as a promising therapy for managing various diseases. The book begins with an introduction to the immune system and the ways in which it can be modulated. This is followed by a discussion on the various diseases and disorders associated with the immune system, including autoimmune disorders, allergies, and immune deficiency conditions. The natural sources of immunomodulators, including plants, herbs, and other natural substances is also explained along with the importance of standardizing natural immunomodulator drugs, including the methods used to ensure their quality and consistency. The book also delves into the chemistry and analytical techniques used to study immunomodulators, clinical and pre-clinical bioassays. The next couple of chapters focus on the use of natural immunomodulators in cancer, the therapy of cancer and infectious diseases. Drug delivery and the strategy and regulatory perspective for natural immunomodulators. The final 2 chapters round up the contents with information about synthetic immunomodulators and the future perspective for the use of immunomodulators in disease management. Natural Immunomodulators: Promising Therapy for Disease Management is a comprehensive guide to the use of natural immunomodulators as a therapy for various diseases, and is a valuable resource for professionals and students interested in this topic. The book is aimed at health care professionals such as medical doctors, nurses, pharmacists, and life science and nutritionist professionals, as well as students.

Epidemiology of Endocrine Tumors

Jahangir Moini,Craig Badolato,Raheleh Ahangari
Epidemiology of Endocrine Tumors Book PDF

Author : Jahangir Moini,Craig Badolato,Raheleh Ahangari
Publisher : Elsevier
Page : 570 pages
File Size : 46,9 Mb
Release : 2021-03-03
Category : Medical
ISBN : 9780128232668

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Epidemiology of Endocrine Tumors by Jahangir Moini,Craig Badolato,Raheleh Ahangari Pdf

Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals Focuses on the impact upon costs and patient deaths due to complications of these tumors Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors Provides review questions with an answer key and detailed glossary

Global Epidemiology of Cancer

Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato
Global Epidemiology of Cancer Book PDF

Author : Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato
Publisher : John Wiley & Sons
Page : 676 pages
File Size : 49,8 Mb
Release : 2022-03-22
Category : Medical
ISBN : 9781119817185

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Global Epidemiology of Cancer by Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato Pdf

GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding the mortality and morbidity of cancer, and how we can prevent, diagnose, and treat the disease. Prevention of cancer is essential for saving lives. Prevalence and incidence of cancer are key factors that each government and population must be aware of. Advances in the study of cancer occur on a regular basis, and this book provides the latest insights about relationships between the disease and stem cells, tumorigenesis, molecular interactions, pathways, channels, and immunity. Global Epidemiology of Cancer: Diagnosis and Treatment meets the needs of readers by providing current information about epidemiology (including molecular epidemiology), diagnosis, and treatment. Providing logical, step-by-step information on various cancers, this book consolidates all of the most up-to-date information and data from verified studies on all different types of cancers in the United States and throughout the world. Chapters are presented so that each includes an overview, clinical manifestations, epidemiology, pathophysiology, etiology and risk factors, diagnosis, treatment, prevention, and prognosis. Global Epidemiology of Cancer: Diagnosis and Treatment will be invaluable to graduate and postgraduate students, including medical students; nurses; physician assistants; residents in oncology; public health students and allied health students.

Drug Delivery Systems

Anonim
Drug Delivery Systems Book PDF

Author : Anonim
Publisher : Academic Press
Page : 792 pages
File Size : 52,7 Mb
Release : 2019-10-23
Category : Medical
ISBN : 9780128145081

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Drug Delivery Systems by Anonim Pdf

Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and product development topics are also explored. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of drug delivery systems within the pharmaceutical sciences industry and research, as well as in chemical engineering. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists. This book provides a comprehensive examination that is suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnologies, and related industries. Provides up-to-date information on how to translate the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as oral, parenteral, transdermal and inhalational Contains extensive references and further reading for course and self-study

Viral Vectors in Cancer Immunotherapy

Anonim
Viral Vectors in Cancer Immunotherapy Book PDF

Author : Anonim
Publisher : Elsevier
Page : 276 pages
File Size : 49,6 Mb
Release : 2023-08-02
Category : Science
ISBN : 9780443192500

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Viral Vectors in Cancer Immunotherapy by Anonim Pdf

Viral Vectors in Cancer Immunotherapy, Volume 379 in the International Review of Cell and Molecular Biology presents the latest on cancer immunotherapy and how it has transformed cancer treatment through advances in immune checkpoint inhibitors and adoptive cell therapy. Chapters in this new release include Past, present and future of viral vectors in cancer immunotherapy, Alphaviruses in cancer immunotherapy, Adenoviral-based cancer gene therapy, Armored modified vaccinia Ankara in cancer immunotherapy, Strategies of Semliki Forest virus in immuno-oncology, Maraba virus in cancer immunotherapy, Oncolytic viruses in hematological malignancies, Oncolytic virus for cancer therapies: Overview and future directions, and more. The use of genetically modified viruses allows the expression of pro-inflammatory molecules, while the immune system receives danger signals from the viruses themselves. In some cases, the virus can also induce tumor cell death. This book will review advances in virus-based cancer immunotherapy in both solid tumors and hematologic malignancies. Provides an overview of the landscape of virotherapy for solid tumors and hematologic malignancies Reviews advances in alphaviruses, adenoviruses, vaccinia viruses and Maraba virus Presents lessons on how to improve viruses to enhance immune responses

Drying Technologies for Biotechnology and Pharmaceutical Applications

Satoshi Ohtake,Ken-ichi Izutsu,David Lechuga-Ballesteros
Drying Technologies for Biotechnology and Pharmaceutical Applications Book PDF

Author : Satoshi Ohtake,Ken-ichi Izutsu,David Lechuga-Ballesteros
Publisher : John Wiley & Sons
Page : 400 pages
File Size : 42,5 Mb
Release : 2020-02-03
Category : Medical
ISBN : 9783527802098

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Drying Technologies for Biotechnology and Pharmaceutical Applications by Satoshi Ohtake,Ken-ichi Izutsu,David Lechuga-Ballesteros Pdf

A comprehensive source of information about modern drying technologies that uniquely focus on the processing of pharmaceuticals and biologicals Drying technologies are an indispensable production step in the pharmaceutical industry and the knowledge of drying technologies and applications is absolutely essential for current drug product development. This book focuses on the application of various drying technologies to the processing of pharmaceuticals and biologicals. It offers a complete overview of innovative as well as standard drying technologies, and addresses the issues of why drying is required and what the critical considerations are for implementing this process operation during drug product development. Drying Technologies for Biotechnology and Pharmaceutical Applications discusses the state-of-the-art of established drying technologies like freeze- and spray- drying and highlights limitations that need to be overcome to achieve the future state of pharmaceutical manufacturing. The book also describes promising next generation drying technologies, which are currently used in fields outside of pharmaceuticals, and how they can be implemented and adapted for future use in the pharmaceutical industry. In addition, it deals with the generation of synergistic effects (e.g. by applying process analytical technology) and provides an outlook toward future developments. -Presents a full technical overview of well established standard drying methods alongside various other drying technologies, possible improvements, limitations, synergies, and future directions -Outlines different drying technologies from an application-oriented point of view and with consideration of real world challenges in the field of drug product development -Edited by renowned experts from the pharmaceutical industry and assembled by leading experts from industry and academia Drying Technologies for Biotechnology and Pharmaceutical Applications is an important book for pharma engineers, process engineers, chemical engineers, and others who work in related industries.

Nanoarchitectonics for Brain Drug Delivery

Anurag Kumar Singh,Vivek K. Chaturvedi,Jay Singh
Nanoarchitectonics for Brain Drug Delivery Book PDF

Author : Anurag Kumar Singh,Vivek K. Chaturvedi,Jay Singh
Publisher : CRC Press
Page : 381 pages
File Size : 53,9 Mb
Release : 2024-02-22
Category : Technology & Engineering
ISBN : 9781003851844

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Nanoarchitectonics for Brain Drug Delivery by Anurag Kumar Singh,Vivek K. Chaturvedi,Jay Singh Pdf

This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain delivery Provides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancer Discusses key advances in the development of polymer nanoparticles for drug delivery to the CNS Reviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disorders This book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.

Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs

Bojan Čalija
Microsized and Nanosized Carriers for Nonsteroidal Anti Inflammatory Drugs Book PDF

Author : Bojan Čalija
Publisher : Academic Press
Page : 284 pages
File Size : 50,7 Mb
Release : 2017-01-03
Category : Medical
ISBN : 9780128040805

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Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs by Bojan Čalija Pdf

Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits provides a unique and complete overview of novel formulation strategies for improvement of the delivery of NSAIDs via encapsulation in microsized and nanosized carriers composed of different materials of natural and synthetic origin. This book presents the latest research on advances and limitations of both microsized and nanosized drug carriers and NSAIDs before discussing the formulation aspects of these drug carriers that are intended for oral, dermal, and transdermal administration of NSAIDs. In addition, functionality of these materials as potential excipients for microsized and nanosized carriers is discussed and debated. Practical solutions for improving effectiveness of these drugs are included throughout the book, making this an important resource for graduate students, professors, and researchers in the pharmaceutical sciences. Covers a wide range of microsized and nanosized carriers in one resource, including particulate carriers (microparticles, nanoparticles, and zeolites) and the soft colloidal carriers, such as micro-emulsions and nano-emulsions Presents the reader with various formulation approaches dependent on the characteristics of the material, model drug, and desired route of administration Approaches are based on the latest research in the area and formulation strategies may have broader applications to the encapsulation of other active pharmaceutical ingredients

Nanobiotechnology in Bioformulations

Ram Prasad,Vivek Kumar,Manoj Kumar,Devendra Choudhary
Nanobiotechnology in Bioformulations Book PDF

Author : Ram Prasad,Vivek Kumar,Manoj Kumar,Devendra Choudhary
Publisher : Springer
Page : 491 pages
File Size : 44,9 Mb
Release : 2019-07-04
Category : Technology & Engineering
ISBN : 9783030170615

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Nanobiotechnology in Bioformulations by Ram Prasad,Vivek Kumar,Manoj Kumar,Devendra Choudhary Pdf

With the recent shift of chemical fertilizers and pesticides to organic agriculture, the employment of microbes that perform significant beneficial functions for plants has been highlighted. This book presents timely discussion and coverage on the use of microbial formulations, which range from powdered or charcoal-based to solution and secondary metabolite-based bioformulations. Bioformulation development of biofertilizers and biopesticides coupled with the advantages of nanobiotechnology propose significant applications in the agricultural section including nanobiosensors, nanoherbicides, and smart transport systems for the regulated release of agrochemical. Moreover, the formulation of secondary metabolites against individual phytopathogens could be used irrespective of geographical positions with higher disease incidences. The prospective advantages and uses of nanobiotechnology generate tremendous interest, as it could augment production of agricultural produce while being cost-effective both energetically and economically. This bioformulation approach is incomparable to existing technology, as the bioformulation would explicitly target the particular pathogen without harming the natural microbiome of the ecosystem. Nanobiotechnology in Bioformulations covers the constraints associated with large-scale development and commercialization of bioinoculant formations. Furthermore, exclusive emphasis is be placed on next-generation efficient bioinoculants having secondary metabolite formulations with longer shelf life and advanced competence against several phytopathogens. Valuable chapters deal with bioformulation strategies that use divergent groups of the microbiome and include detailed diagrammatic and pictorial representation. This book will be highly beneficial for both experts and novices in the fields of microbial bioformulation, nanotechnology, and nano-microbiotechnology. It discusses the prevailing status and applications available for microbial researchers and scientists, agronomists, students, environmentalists, agriculturists, and agribusiness professionals, as well as to anyone devoted to sustaining the ecosystem.