Nutrition Gut Microbiota And Immunity Therapeutic Targets For Ibd

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Nutrition, Gut Microbiota and Immunity: Therapeutic Targets for IBD

Author : J.D. Lewis,F.M. Ruemmele,G.D. Wu
Publisher : Karger Medical and Scientific Publishers
Page : 180 pages
File Size : 47,9 Mb
Release : 2014-09-10
Category : Medical
ISBN : 9783318026702

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Nutrition, Gut Microbiota and Immunity: Therapeutic Targets for IBD by J.D. Lewis,F.M. Ruemmele,G.D. Wu Pdf

Inflammatory Bowel Disease (IBD) is a chronic debilitating disorder that occurs at any age and in populations around the world. Its pathogenesis is believed to involve a combination of genetic susceptibility, immune and external environmental factors, including the gut microbiota. Changing factors such as diet and the human gut microbiota may thus be a viable alternative to suppressing the innate and adaptive immune responses. The book at hand starts with a summary of the current understanding of the epidemiology and biologic underpinnings that manifest as IBD. Next, the gut microbiota, its function, and how it may interact with nutritional status in perpetuating IBD are looked at, followed by discussions on the potential for manipulation of the gut microbiota through the use of prebiotics, probiotics, antibiotics, and fecal transplantation. Chapters on the current role of and future prospects for nutritional interventions in the management of IBD complete the topics presented.

Breaking the Vicious Cycle

Author : Elaine Gloria Gottschall
Publisher : Unknown
Page : 205 pages
File Size : 50,6 Mb
Release : 2016-09-05
Category : Electronic
ISBN : 1626547327

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Breaking the Vicious Cycle by Elaine Gloria Gottschall Pdf

Physiological and Clinical Aspects of Short-Chain Fatty Acids

Author : John H. Cummings,John L. Rombeau,Takashi Sakata
Publisher : Cambridge University Press
Page : 602 pages
File Size : 49,5 Mb
Release : 2004-12-02
Category : Medical
ISBN : 0521616131

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Physiological and Clinical Aspects of Short-Chain Fatty Acids by John H. Cummings,John L. Rombeau,Takashi Sakata Pdf

This is the first comprehensive volume to look at the importance of short-chain fatty acids in digestion, the function of the large intestine and their role in human health. Short-chain fatty acids are the major product of bacterial fermentation of dietary carbohydrates in the human and animal large intestine. They represent the major end products of digestive processes occurring in the caecum and large intestine. As such, they form an important dietary component and it is increasingly recognised that they may have a significant role in protecting against large bowel cancer and in metabolism. Prepared by an international team of contributors who are at the forefront of this area of research, this volume will be an essential source of reference for gastroenterologists, nutritionists and others active in this area.

Nutrition in Inflammatory Bowel Disease (IBD)

Author : Maitreyi Raman
Publisher : Unknown
Page : 1 pages
File Size : 52,7 Mb
Release : 2019
Category : Electronic books
ISBN : 3039214403

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Nutrition in Inflammatory Bowel Disease (IBD) by Maitreyi Raman Pdf

The purpose of this Special Issue "Nutrition in Inflammatory Bowel Disease (IBD)" is to increase knowledge regarding the role of dietary composition and effects in IBD, describing the prevalence of malnutrition in IBD and the effect on clinical outcomes, discussing methods of nutrition risk screening and assessment in IBD, and reviewing mechanisms through which diet and dietary components may affect disease severity. The articles focus on the following areas: Dietary Composition/Therapy Interventions in Ulcerative Colitis and effects on outcomes; Dietary Composition/Therapy Interventions in Crohn's Disease and effects on outcomes; Nutrition Risk Screening and Assessment in IBD; Mechanisms of Diet in the pathogenesis of IBD.

Bugs as Drugs

Author : Robert A. Britton,Patrice D. Cani
Publisher : John Wiley & Sons
Page : 514 pages
File Size : 49,7 Mb
Release : 2020-07-02
Category : Medical
ISBN : 9781555819705

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Bugs as Drugs by Robert A. Britton,Patrice D. Cani Pdf

Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

The Gut Microbiome in Health and Disease

Author : Dirk Haller
Publisher : Springer
Page : 356 pages
File Size : 55,9 Mb
Release : 2018-07-27
Category : Medical
ISBN : 9783319905457

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The Gut Microbiome in Health and Disease by Dirk Haller Pdf

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

The Microbiota in Gastrointestinal Pathophysiology

Author : Martin H. Floch,Yehuda Ringel,W. Allen Walker
Publisher : Academic Press
Page : 442 pages
File Size : 52,5 Mb
Release : 2016-11-16
Category : Medical
ISBN : 9780128040621

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The Microbiota in Gastrointestinal Pathophysiology by Martin H. Floch,Yehuda Ringel,W. Allen Walker Pdf

The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects Explores the gut microbiota as a therapeutic target Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field Serves as a ‘one-stop’ shop for a topic that’s currently spread across a number of various journals

Probiotics, Prebiotics, and Synbiotics

Author : Ronald Ross Watson,Victor R. Preedy
Publisher : Academic Press
Page : 938 pages
File Size : 50,9 Mb
Release : 2015-09-23
Category : Medical
ISBN : 9780128023716

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Probiotics, Prebiotics, and Synbiotics by Ronald Ross Watson,Victor R. Preedy Pdf

Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion reviews and presents new hypotheses and conclusions on the effects of different bioactive components of probiotics, prebiotics, and synbiotics to prevent disease and improve the health of various populations. Experts define and support the actions of bacteria; bacteria modified bioflavonoids and prebiotic fibrous materials and vegetable compounds. A major emphasis is placed on the health-promoting activities and bioactive components of probiotic bacteria. Offers a novel focus on synbiotics, carefully designed prebiotics probiotics combinations to help design functional food and nutraceutical products Discusses how prebiotics and probiotics are complementary and can be incorporated into food products and used as alternative medicines Defines the variety of applications of probiotics in health and disease resistance and provides key insights into how gut flora are modified by specific food materials Includes valuable information on how prebiotics are important sources of micro-and macronutrients that modify body functions

Intestinal Immune System

Author : Soichiro Miura,Ryota Hokari,Shunsuke Komoto
Publisher : Morgan & Claypool Publishers
Page : 125 pages
File Size : 52,7 Mb
Release : 2011
Category : Medical
ISBN : 9781615041442

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Intestinal Immune System by Soichiro Miura,Ryota Hokari,Shunsuke Komoto Pdf

These negative regulatory mechanisms of the intestinal immune system are disturbed in certain disease conditions, causing the immunocompetent cells to respond to food components and commensal bacteria by becoming activated and to overproduce inflammatory cytokines and chemokines. These disease conditions include food allergies, such as celiac disease, and the inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, although their exact etiological mechanisms remain to be revealed. --Book Jacket.

Probiotics, Prebiotics and Synbiotics

Author : Parmjit Singh Panesar,Anil Kumar Anal
Publisher : John Wiley & Sons
Page : 500 pages
File Size : 44,5 Mb
Release : 2022-01-11
Category : Technology & Engineering
ISBN : 9781119701231

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Probiotics, Prebiotics and Synbiotics by Parmjit Singh Panesar,Anil Kumar Anal Pdf

In Probiotics, Prebiotics and Synbiotics: Technological Advancements Towards Safety and Industrial Applications, a team of distinguished researchers delivers an insightful exploration of various aspects of functional foods. The book includes information about critical facets of the production of these beneficial compounds, recent technological developments in the field, and their present and future commercial potential. The authors describe their mechanisms of action and their applications in several sectors. Probiotics, Prebiotics and Synbiotics is divided into five parts. A general introduction about these substances begins the book and is followed by discussions of common probiotics, prebiotics, and synbiotics. Finally, a treatment of safety issues and regulatory claims, as well as their market potential, rounds out the resource. Perfect for researchers, industry practitioners, and students working in or studying food processing and food microbiology, Probiotics, Prebiotics and Synbiotics is also an invaluable resource for professionals working in the field of food biotechnology.

Health and Nutrition in Adolescents and Young Women: Preparing for the Next Generation

Author : Z.A. Bhutta,M. Makrides,A.M. Prentice
Publisher : Karger Medical and Scientific Publishers
Page : 144 pages
File Size : 54,6 Mb
Release : 2014-12-15
Category : Medical
ISBN : 9783318026726

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Health and Nutrition in Adolescents and Young Women: Preparing for the Next Generation by Z.A. Bhutta,M. Makrides,A.M. Prentice Pdf

Nutrition of young women and its effect on offspring is an almost neglected topic in developed and developing countries alike. Under- as well as overnutrition of the mother can negatively program the child's health: Maternal undernutrition and micronutrient deficiencies are related to both low birth weight and intrauterine growth retardation. Moreover, they also result in negative epigenetic programming both during conception and in the newborn. Obese mothers, on the other hand, may produce offspring with a lower life expectancy, a fact which could be related to the higher risk of developing metabolic syndrome in adult life. This book provides insights into the influence of maternal health and nutrition on both fetal and postnatal growth and health of the offspring. Contributions focus on future mothers from their adolescence to pregnancy, thus providing valuable information for the clinician involved in the care of adolescents and young women.

Processes of Believing: The Acquisition, Maintenance, and Change in Creditions

Author : Hans-Ferdinand Angel,Lluis Oviedo,Raymond F. Paloutzian,Anne L.C. Runehov,Rüdiger J. Seitz
Publisher : Springer
Page : 476 pages
File Size : 47,5 Mb
Release : 2017-04-13
Category : Philosophy
ISBN : 9783319509242

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Processes of Believing: The Acquisition, Maintenance, and Change in Creditions by Hans-Ferdinand Angel,Lluis Oviedo,Raymond F. Paloutzian,Anne L.C. Runehov,Rüdiger J. Seitz Pdf

This volume answers the question: Why do we believe what we believe? It examines current research on the concept of beliefs, and the development in our understanding of the process of believing. It takes into account empirical findings in the field of neuroscience regarding the processes that underlie beliefs, and discusses the notion that beyond the interactive exploratory analysis of sensory information from the complex outside world, humans engage in an evaluative analysis by which they attribute personal meaning and relevance to the probabilistic representations of objects and events. Beliefs exert a strong influence on behaviour, decision-making, and identifying and solving problems. Despite their importance, beliefs have until recently not been at the centre of scientific interest. In fact, “belief” is an ill-defined phenomenon. From a transdisciplinary perspective the actual approaches to understanding belief seem incompatible as they attempt to highlight such different topics as “belief – religion”, “belief – spirituality”, “belief – faith”, “belief – knowledge”, “belief – attitude”, “belief – disbelief”, “belief – illusion”, and “believing – brain function”. This situation contradicts the idea that belief is close to pathological phenomena and that it should be eliminated from scientific discussions. Rather, believing is fundamental for understanding the many problems of every-day life. In fact, the book shows that beliefs are relevant for politics, international affairs, economy, law, or religions also in modern societies. This book presents the increasing scientific interest in beliefs and believing, and reflects the change in focus from the content aspect of belief towards the fluid nature of believing.

Pediatric Inflammatory Bowel Disease

Author : Petar Mamula,Jonathan E. Markowitz,Robert N. Baldassano
Publisher : Springer Science & Business Media
Page : 573 pages
File Size : 43,6 Mb
Release : 2012-12-14
Category : Medical
ISBN : 9781461450610

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Pediatric Inflammatory Bowel Disease by Petar Mamula,Jonathan E. Markowitz,Robert N. Baldassano Pdf

Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.

Inflammatory Bowel Disease

Author : Stephan R. Targan,Fergus Shanahan,Loren C. Karp
Publisher : Springer Science & Business Media
Page : 891 pages
File Size : 40,5 Mb
Release : 2007-05-16
Category : Medical
ISBN : 9780387258089

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Inflammatory Bowel Disease by Stephan R. Targan,Fergus Shanahan,Loren C. Karp Pdf

Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders is explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

Immune-deficient Animals in Biomedical Research

Author : Jørgen Rygaard
Publisher : S. Karger AG (Switzerland)
Page : 444 pages
File Size : 44,9 Mb
Release : 1987
Category : Medical
ISBN : UOM:39015012463330

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Immune-deficient Animals in Biomedical Research by Jørgen Rygaard Pdf