Oecd Guidelines For The Testing Of Chemicals Section 4 Health Effects Summary Of Considerations In The Report From The Oecd Expert Groups On Short Term And Long Term Toxicology

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OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology

Author : OECD
Publisher : OECD Publishing
Page : 12 pages
File Size : 43,8 Mb
Release : 2006-09-11
Category : Electronic
ISBN : 9789264035447

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OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology by OECD Pdf

OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method

Author : OECD
Publisher : OECD Publishing
Page : 27 pages
File Size : 49,7 Mb
Release : 2009-09-08
Category : Electronic
ISBN : 9789264076037

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OECD Guidelines for the Testing of Chemicals, Section 4: Health Effects Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method by OECD Pdf

The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

Author : OECD
Publisher : OECD Publishing
Page : 16 pages
File Size : 49,6 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071209

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies by OECD Pdf

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...

OECD Guidelines for the Testing of Chemicals / Section 2: Effects on Biotic Systems Summary of Considerations in the Report from the OECD Expert Group on Ecotoxicology

Author : OECD
Publisher : OECD Publishing
Page : 10 pages
File Size : 40,9 Mb
Release : 2006-09-11
Category : Electronic
ISBN : 9789264022386

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OECD Guidelines for the Testing of Chemicals / Section 2: Effects on Biotic Systems Summary of Considerations in the Report from the OECD Expert Group on Ecotoxicology by OECD Pdf

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity

Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 49,8 Mb
Release : 2024-06-25
Category : Electronic
ISBN : 9789264070608

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 403: Acute Inhalation Toxicity by OECD Pdf

This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study

Author : OECD
Publisher : OECD Publishing
Page : 8 pages
File Size : 53,7 Mb
Release : 1981-05-12
Category : Electronic
ISBN : 9789264070745

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study by OECD Pdf

This study relates to the analysis, via dermal application, of the health hazard of solid or liquid test substance. This method is composed of two tests: the main test and the limit test. This Test Guideline is intended for use with the adult rat ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study

Author : OECD
Publisher : OECD Publishing
Page : 9 pages
File Size : 42,6 Mb
Release : 1981-05-12
Category : Electronic
ISBN : 9789264070769

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 411: Subchronic Dermal Toxicity: 90-day Study by OECD Pdf

This study relates to the analysis, via dermal application, of the health hazards of solid or liquid test substance. It may be carried out after initial information obtained by acute testing. This method is composed of the main test and the limit ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 46,9 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264071223

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies by OECD Pdf

The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure

Author : OECD
Publisher : OECD Publishing
Page : 14 pages
File Size : 53,8 Mb
Release : 2002-02-08
Category : Electronic
ISBN : 9789264070943

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure by OECD Pdf

A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure

Author : OECD
Publisher : OECD Publishing
Page : 21 pages
File Size : 52,6 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264284166

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 433: Acute Inhalation Toxicity: Fixed Concentration Procedure by OECD Pdf

This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents

Author : OECD
Publisher : OECD Publishing
Page : 9 pages
File Size : 44,6 Mb
Release : 1998-09-21
Category : Electronic
ISBN : 9789264070721

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents by OECD Pdf

This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...

Engineering Tools for Environmental Risk Management

Author : Katalin Gruiz,Tamas Meggyes,Eva Fenyvesi
Publisher : CRC Press
Page : 596 pages
File Size : 44,9 Mb
Release : 2015-04-27
Category : Science
ISBN : 9781315778778

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Engineering Tools for Environmental Risk Management by Katalin Gruiz,Tamas Meggyes,Eva Fenyvesi Pdf

Chemical substances, physical agents and built structures exhibit various types of hazard due to their inherent toxic, mutagenic, carcinogenic, reprotoxic and sensitizing character or damaging to the immune and hormone system. The first steps in managing an environment contaminated by chemical substances are characterization of hazards and quantifi

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study

Author : OECD
Publisher : OECD Publishing
Page : 15 pages
File Size : 43,8 Mb
Release : 2018-06-27
Category : Electronic
ISBN : 9789264070806

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 413: Subchronic Inhalation Toxicity: 90-day Study by OECD Pdf

This revised Test Guideline has been designed to fully characterize test article toxicity by the inhalation route for a subchronic duration (90 days), and to provide robust data for quantitative inhalation risk assessments. Groups of 10 male and 10 ...

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure

Author : OECD
Publisher : OECD Publishing
Page : 27 pages
File Size : 50,8 Mb
Release : 2022-06-30
Category : Electronic
ISBN : 9789264071049

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure by OECD Pdf

The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling of chemicals. It is easiest to ...

Introduction to Environmental Toxicology

Author : Wayne Landis,Ruth Sofield,Ming-Ho Yu,Wayne G. Landis,Ruth M. Sofield
Publisher : CRC Press
Page : 536 pages
File Size : 55,9 Mb
Release : 2010-12-16
Category : Science
ISBN : 9781439804100

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Introduction to Environmental Toxicology by Wayne Landis,Ruth Sofield,Ming-Ho Yu,Wayne G. Landis,Ruth M. Sofield Pdf

After fifteen years and three editions, Introduction to Environmental Toxicology: Molecular Substructures to Ecological Landscapes has become a standard that defines the field of environmental toxicology, and the fourth edition is no exception. The authors take an integrated approach to environmental toxicology that emphasizes scale and context as important factors in understanding effects and management options. New in the Fourth Edition: New author, Dr. Ruth M. Sofield 8-page color insert New chapter on fate and transport of contaminants Emphasis on the use of all types of models in understanding how nature works Revised sections on synergy and atrazine toxicity Updated coverage of the analysis of impacts to populations, communities and ecosystems Enlarged risk assessment chapter with an in-depth description of a regional scale risk assessment This edition benefits from the insight of a new author, Dr. Ruth M. Sofield, who prepared the new chapter on the fate and transport of contaminants. The relationship between structure and toxicological properties has been a major theme of this book since its inception and this new chapter expands this fundamental concept to include fate and transport. In the early chapters the use of models in science is discussed and this theme carries throughout the rest of the book. So much has changed in the fifteen years since the publication of the first edition. The mid-1990s seem so long ago, when our understanding of environmental toxicology was very basic. Ecological risk assessment was in its very early stages and the consideration of the effects of toxicants on landscapes was only beginning. Computation was still hard, genes stayed put, and it was only becoming recognized that xenobiotics could have hormonal effects — developments that are taken for granted in this edition. Written by authors who teach this subject, a feature that is reflected in their straightforward style, the book provides a foundation for understanding environmental toxicology and its application.