One Renegade Cell

Author : Robert A Weinberg
Publisher : Basic Books
Page : 180 pages
File Size : 50,8 Mb
Release : 2008-08-04
Category : Science
ISBN : 9780786724017

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One Renegade Cell by Robert A Weinberg Pdf

Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured. Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation. This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.

Author : Robert Allan Weinberg
Publisher : Unknown
Page : 170 pages
File Size : 40,9 Mb
Release : 1998
Category : Cancer
ISBN : 0297816454

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One Renegade Cell by Robert Allan Weinberg Pdf

Author : Robert Allan Weinberg
Publisher : W H Freeman & Company
Page : 274 pages
File Size : 52,8 Mb
Release : 1998-01-01
Category : Medical
ISBN : 0716732831

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Racing to the Beginning of the Road by Robert Allan Weinberg Pdf

Details the latest advances in cancer research and the politics involved, and examines the history of cancer theories

Author : Craig A. Almeida,Sheila A. Barry
Publisher : John Wiley & Sons
Page : 424 pages
File Size : 54,7 Mb
Release : 2011-08-26
Category : Science
ISBN : 9781444357394

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Cancer by Craig A. Almeida,Sheila A. Barry Pdf

“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.

Author : Kat Arney
Publisher : BenBella Books
Page : 256 pages
File Size : 51,5 Mb
Release : 2020-10-20
Category : Medical
ISBN : 9781950665518

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Rebel Cell by Kat Arney Pdf

Why do we get cancer? Is it our modern diets and unhealthy habits? Chemicals in the environment? An unwelcome genetic inheritance? Or is it just bad luck? The answer is all of these and none of them. We get cancer because we can't avoid it—it's a bug in the system of life itself. Cancer exists in nearly every animal and has afflicted humans as long as our species has walked the earth. In Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal, Kat Arney reveals the secrets of our most formidable medical enemy, most notably the fact that it isn't so much a foreign invader as a double agent: cancer is hardwired into the fundamental processes of life. New evidence shows that this disease is the result of the same evolutionary changes that allowed us to thrive. Evolution helped us outsmart our environment, and it helps cancer outsmart its environment as well—alas, that environment is us. Explaining why "everything we know about cancer is wrong," Arney, a geneticist and award-winning science writer, guides readers with her trademark wit and clarity through the latest research into the cellular mavericks that rebel against the rigid biological "society" of the body and make a leap towards anarchy. We need to be a lot smarter to defeat such a wily foe—smarter even than Darwin himself. In this new world, where we know that every cancer is unique and can evolve its way out of trouble, the old models of treatment have reached their limits. But we are starting to decipher cancer's secret evolutionary playbook, mapping the landscapes in which these rogue cells survive, thrive, or die, and using this knowledge to predict and confound cancer's next move. Rebel Cell is a story about life and death, hope and hubris, nature and nurture. It's about a new way of thinking about what this disease really is and the role it plays in human life. Above all, it's a story about where cancer came from, where it's going, and how we can stop it.

Author : Jessica Wapner
Publisher : The Experiment, LLC
Page : 345 pages
File Size : 43,9 Mb
Release : 2014-04-08
Category : Health & Fitness
ISBN : 9781615191659

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The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment by Jessica Wapner Pdf

One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Author : Weinberg, Robert A.
Publisher : W.W. Norton & Company
Page : 6 pages
File Size : 55,7 Mb
Release : 2013-05-24
Category : Science
ISBN : 9780815345282

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The Biology of Cancer by Weinberg, Robert A. Pdf

Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.

Author : Athena Aktipis
Publisher : Princeton University Press
Page : 256 pages
File Size : 52,6 Mb
Release : 2020-03-24
Category : Medical
ISBN : 9780691163840

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The Cheating Cell by Athena Aktipis Pdf

A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked because the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments. Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer’s ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn’t mean we should give up on treating cancer—in fact, evolutionary approaches offer new and promising options for the disease’s prevention and treatments that aim at long-term management rather than simple eradication. Looking across species—from sponges and cacti to dogs and elephants—we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future—and that we cannot win a war against evolution—treatments can become smarter, more strategic, and more humane. Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer’s fundamental nature and our relationship to it.

Author : Boyce Rensberger
Publisher : Oxford University Press, USA
Page : 314 pages
File Size : 50,6 Mb
Release : 1996
Category : Cells
ISBN : UOM:49015002472430

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Life Itself by Boyce Rensberger Pdf

In Amazing Life, Boyce Rensberger takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. The hottest topics in biomedical research are covered.

Author : Nadine Artemis
Publisher : North Atlantic Books
Page : 449 pages
File Size : 53,8 Mb
Release : 2017-11-14
Category : Body, Mind & Spirit
ISBN : 9781583949702

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Renegade Beauty by Nadine Artemis Pdf

Rethink conventional notions of beauty and wellness, abandon established regimes and commercial products, and embrace your “renegade” beauty In this essential full-color guide, Nadine Artemis introduces readers to the concept of "renegade" beauty—a practice of doing less and allowing the elements and the life force of nature to revive the body, skin, and soul so our natural radiance can shine through. Anyone stuck in perpetual loops of new products, facials, and dermatologist appointments will find answers as Artemis illuminates the energizing elements of sun, fresh air, water, the earth, and plants. This book is a comprehensive resource for anyone who wants to simplify their self-care routine, take their health into their own hands, and discover their own radiant beauty.

Author : Laurence Ralph
Publisher : University of Chicago Press
Page : 273 pages
File Size : 41,8 Mb
Release : 2014-09-15
Category : Social Science
ISBN : 9780226032719

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Renegade Dreams by Laurence Ralph Pdf

Inner city communities in the US have become junkyards of dreams, to quote Mike Daviswastelands where gangs package narcotics to stimulate the local economy, gunshots occur multiple times on any given day, and dreams of a better life can fade into the realities of poverty and disability. Laurence Ralph lived in such a community in Chicago for three years, conducting interviews and participating in meetings with members of the local gang which has been central to the community since the 1950s. Ralph discovered that the experience of injury, whether physical or social, doesn t always crush dreams into oblivion; it can transform them into something productive: renegade dreams. The first part of this book moves from a critique of the way government officials, as opposed to grandmothers, have been handling the situation, to a study of the history of the historic Divine Knights gang, to a portrait of a duo of gang members who want to be recognized as authentic rappers (they call their musical style crack music ) and the difficulties they face in exiting the gang. The second part is on physical disability, including being wheelchair bound, the prevalence of HIV/AIDS among heroin users, and the experience of brutality at the hands of Chicago police officers. In a final chapter, The Frame, Or How to Get Out of an Isolated Space, Ralph offers a fresh perspective on how to understand urban violence. The upshot is a total portrait of the interlocking complexities, symbols, and vicissitudes of gang life in one of the most dangerous inner city neighborhoods in the US. We expect this study will enjoy considerable readership, among anthropologists, sociologists, and other scholars interested in disability, urban crime, and race."

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
Page : 624 pages
File Size : 42,9 Mb
Release : 2011-08-09
Category : Health & Fitness
ISBN : 9781439170915

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The Emperor of All Maladies by Siddhartha Mukherjee Pdf

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Author : Robert Lanza,Bob Berman
Publisher : BenBella Books
Page : 225 pages
File Size : 53,9 Mb
Release : 2010-05-18
Category : Body, Mind & Spirit
ISBN : 9781935251743

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Biocentrism by Robert Lanza,Bob Berman Pdf

Robert Lanza is one of the most respected scientists in the world — a US News & World Report cover story called him a “genius" and a “renegade thinker," even likening him to Einstein. Lanza has teamed with Bob Berman, the most widely read astronomer in the world, to produce Biocentrism, a revolutionary new view of the universe. Every now and then a simple yet radical idea shakes the very foundations of knowledge. The startling discovery that the world was not flat challenged and ultimately changed the way people perceived themselves and their relationship with the world. For most humans of the 15th century, the notion of Earth as ball of rock was nonsense. The whole of Western, natural philosophy is undergoing a sea change again, increasingly being forced upon us by the experimental findings of quantum theory, and at the same time, towards doubt and uncertainty in the physical explanations of the universe's genesis and structure. Biocentrism completes this shift in worldview, turning the planet upside down again with the revolutionary view that life creates the universe instead of the other way around. In this paradigm, life is not an accidental byproduct of the laws of physics. Biocetnrism takes the reader on a seemingly improbable but ultimately inescapable journey through a foreign universe—our own—from the viewpoints of an acclaimed biologist and a leading astronomer. Switching perspective from physics to biology unlocks the cages in which Western science has unwittingly managed to confine itself. Biocentrism will shatter the reader's ideas of life--time and space, and even death. At the same time it will release us from the dull worldview of life being merely the activity of an admixture of carbon and a few other elements; it suggests the exhilarating possibility that life is fundamentally immortal. The 21st century is predicted to be the Century of Biology, a shift from the previous century dominated by physics. It seems fitting, then, to begin the century by turning the universe outside-in and unifying the foundations of science with a simple idea discovered by one of the leading life-scientists of our age. Biocentrism awakens in readers a new sense of possibility, and is full of so many shocking new perspectives that the reader will never see reality the same way again.

Author : Harold Varmus,Robert Allan Weinberg
Publisher : Times Books
Page : 214 pages
File Size : 49,5 Mb
Release : 1993-01-01
Category : Medical
ISBN : 0716750376

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Genes and the Biology of Cancer by Harold Varmus,Robert Allan Weinberg Pdf

Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells

Author : Janelle Hanchett
Publisher : Hachette Books
Page : 284 pages
File Size : 53,7 Mb
Release : 2018-05-01
Category : Biography & Autobiography
ISBN : 9780316549431

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I'm Just Happy to Be Here by Janelle Hanchett Pdf

"A refreshingly raw, contrasting perspective on the foolproof idea of motherhood." -- POPSUGAR "By turns painful and funny... A searingly candid memoir." -- Kirkus "Far from your cookie-cutter story of addiction . . . [I'm Just Happy to Be Here] describes Hanchett's journey to recovery and sobriety in imperfect and unconventional ways." -- Bustle In this unflinching and wickedly funny memoir, Janelle Hanchett tells the story of finding her way home. And then, actually staying there. Drawing us into the wild, heartbreaking mind of the addict, Hanchett carries us from motherhood at 21 with a man she'd known three months to cubicles and whiskey-laden domesticity, from judging meth addicts in rehab to therapists who "seem to pull diagnoses out of large, expensive hats." With warmth, wit, and searing B.S. detectors turned mostly toward herself, Hanchett invites us to laugh when we probably shouldn't and to rejoice at the unconventional redemption she finds in desperation and in a misfit mentor who forces her to see the truth of herself. A story of ego and forced humility, of fierce honesty and jagged love, of the kind of failure that forces us to re-create our lives, Hanchett writes with rare candor, scorching the "sanctity of motherhood," and leaving beauty in the ashes.