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Author : John Fried,John Ansley Edwards
Publisher : Unknown
Page : 528 pages
File Size : 50,6 Mb
Release : 1972
Category : Organic compounds
ISBN : MINN:31951000477532B
Author : Anonim
Publisher : Unknown
Page : 464 pages
File Size : 50,5 Mb
Release : 1972
Category : Electronic
ISBN : OCLC:310573239
Author : J. R. Hanson
Publisher : Elsevier
Page : 112 pages
File Size : 49,6 Mb
Release : 2016-06-23
Category : Science
ISBN : 9781483139289
Introduction to Steroid Chemistry is a six-chapter introductory text of the analysis, conformation, and production of steroids. After providing a brief overview of steroid chemistry, this book goes on discussing the application of physical methods to the analysis of structural and stereochemical correlations in steroids, such as UV, infrared, NMR, and mass spectroscopy, optical rotary dispersion, and circular dichroism. The subsequent two chapters describe the influence of steroid conformation and molecular rearrangements on reactions rates and reaction products. The remaining chapters explore the improvements in the synthesis of the estrogenic hormones and the biosynthetic pathways and metabolism of cholesterol. This book will be of value to general and organic chemists, biochemists, and research workers in related subjects.
Author : Carl Djerassi
Publisher : Unknown
Page : 680 pages
File Size : 53,5 Mb
Release : 1963
Category : Science
ISBN : UOM:39015016055918
Author : J. R. Hanson
Publisher : Pergamon
Page : 104 pages
File Size : 47,8 Mb
Release : 1968
Category : Steroids
ISBN : 0080128084
Author : Charles W. Shoppee
Publisher : Unknown
Page : 332 pages
File Size : 49,8 Mb
Release : 1958
Category : Steroids
ISBN : CORNELL:31924002975039
Author : Daniel Lednicer
Publisher : John Wiley & Sons
Page : 154 pages
File Size : 50,7 Mb
Release : 2011-06-20
Category : Science
ISBN : 9781119957294
The term steroid has become virtually synonymous with drug abuse in sport to the majority of the public. However these steroids - androgens - actually comprise only a single relatively small class of biologically active steroids, and are overshadowed by a large collection of compounds, a sizeable number of which are commercial drugs that share the same structural carbon skeleton. The development of these drugs has led to a large body of organic chemistry often denoted as "Steroid Chemistry". Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry. Topics covered include: history, isolation and structure determination of steroids steroid nomenclature and stereochemistry natural sources of steroids synthesis and reactions of aromatic a-ring steroids, androstanes, and pregnanes steroids with a spirolactone at position 17 steroids with hetrocyclic ring A compounds derived from cholesterol Based on the highly successful and student friendly "at a glance" approach, the information is presented in integrated, self contained double page spreads of text and illustrative material. Students of chemistry and pharmacy using Steroid Chemistry at a Glance will find they have a resource with which they can quickly, concisely and confidently acquire, regularly review and revise the basic facts that underpin the properties, synthesis and reactions of this important class of natural products. It will also serve as a handy bench reference for postgraduates and professional chemists.
Author : Robert T. Blickenstaff,Anil C. Ghosh,Gordon C. Wolf
Publisher : Academic Press
Page : 344 pages
File Size : 55,7 Mb
Release : 2013-10-22
Category : Science
ISBN : 9781483216423
Organic Chemistry, Volume 30: Total Synthesis of Steroids provides an overall view of steroid total synthesis, including the general approaches, special problems, stereochemical complexities, expansion or contraction of rings, and insertion of hetero atoms. The book discusses the process of designing total syntheses; the biogenetic-like steroid synthesis, including cyclization of terminal epoxides as well as the total synthesis from nonepoxide precursors; and the synthesis of equilenin, estrone, bisdehydrodoisynolic acid, 18,19-bisnorprogesterone, 19-norpregnanes, and heterocyclic steroids. The text also describes the application of ABD intermediates in the Torgov synthesis; the synthesis of carbocyclics and thiasteroids; and the synthesis from p-anisylcyclohexanes and from C-5, C-8 bridged intermediates. The synthesis based on the type of reaction used in the condensation of the A fragment with the CD portion, as well as the methods of total synthesis in the preparation of 8-azasteroids and 8,13-diazasteroids are also considered. The book further tackles the synthesis of epiandrosterone, cortisone, aldosterone, 3β-hydroxy-5α-pregnan-20-one, latifoline, conessine, and ring C aromatic steroids; the synthesis of trans-benzohydrindane derivatives and other common derivatives; and the synthesis of CD intermediates. Chemists, biochemists, and people involved in the study of steroid total syntheses will find the book invaluable.
Author : A. A. Akhrem
Publisher : Springer Science & Business Media
Page : 368 pages
File Size : 45,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781475705874
Since the appearance of the Russian edition of this monograph (1967), the main tendencies of the development of total synfuesis have not changed. The accelerated accumulation of experimental material is continuing, mainly in the form of the improvement of already-existing synthesis schemes. The main new advance is the development of asymmetric syn theses with intermediates that have made it possible to avoid the main dis advantage of total synthesis - the formation of racemic final compounds. The most important work that has appeared since the appearance of the Russian edition is given in an Appendix to the book. Apart from this, only a very slight rearrangement of the material and of some of the schemes has been carried out for the American edition. A. A. Akhrem Yu. A. Titov Moscow, July 1968 v Preface to the Russian Edition Steroids are one of the most interesting and most widely distributed and, at the same time, one of the most structurally complex groups of natural compounds. In spite of this, the great theoretical and practical importance of steroids for biology and medicine has led to very intensive scientific research work on their synthesis. The numerous methods for obtaining steroids developed at the present time can be divided into four main groups: isolation from natural sources, microbiological synthesis, partial synthesis from natural raw material already containing the steroid skeleton, and, finally, total chemical synthesis from precursors of com paratively simple structure.
Author : William Klyne
Publisher : Unknown
Page : 230 pages
File Size : 47,5 Mb
Release : 1960
Category : Steroids
ISBN : UOM:39015058440390
Author : Barry M. Trost
Publisher : Elsevier
Page : 1174 pages
File Size : 40,5 Mb
Release : 1991
Category : Science
ISBN : 0080405991
Volume 8.
Author : Anonim
Publisher : Unknown
Page : 657 pages
File Size : 44,5 Mb
Release : 1963
Category : Steroids
ISBN : OCLC:221316213
Author : Professor Satyajit D. Sarker,Lutfun Nahar
Publisher : John Wiley & Sons
Page : 414 pages
File Size : 55,7 Mb
Release : 2012-04-13
Category : Science
ISBN : 9781119972846
Steroid dimers are an important group of compounds produced by various marine organisms, and also synthesized in the laboratories. This group of compounds possesses various pharmacological and biological properties, and can also be used to create “molecular umbrellas” for drug delivery. Steroid Dimers: Chemistry and Applications in Drug Design and Delivery provides an up-to-date overview on the chemistry and applications of steroid dimers of natural and synthetic origins. The book includes easy-to-follow synthetic protocols for various classes of important dimeric steroids, source details, valuable spectroscopic data and depiction of unique structural features of natural steroidal dimers, and the Structure-Activity-Relationships (SARs) of some pharmacologically active dimeric steroids. Topics covered include: introduction to steroid dimers synthesis and chemistry of noncyclic and cyclic steroid dimers naturally occurring steroid dimers – cephalostatins, ritterazines and crellastatins biological and pharmacological functions of steroid dimers and their application in drug design and discovery steroid dimers as “molecular umbrellas” for drug delivery Steroid Dimers: Chemistry and Applications in Drug Design and Delivery is an essential guide to this important class of natural and synthetic compounds for researchers and students of natural products chemistry and biochemistry, synthetic organic and medicinal chemistry, and drug design, discovery and delivery.
Author : Norman S. Bhacca,Dudley H. Williams
Publisher : Unknown
Page : 216 pages
File Size : 42,8 Mb
Release : 1964
Category : Science
ISBN : UOM:39015000311822
Author : John Ansley Edwards
Publisher : Unknown
Page : 480 pages
File Size : 40,6 Mb
Release : 1972
Category : Organic compounds
ISBN : MINN:319510004775339