Pathobiology Of Human Disease

Author : Anonim
Publisher : Elsevier
Page : 5000 pages
File Size : 41,8 Mb
Release : 2014-08-01
Category : Medical
ISBN : 9780123864574

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Pathobiology of Human Disease by Anonim Pdf

Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 802 pages
File Size : 44,7 Mb
Release : 2017-11-09
Category : Medical
ISBN : 9780128027875

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Author : Leonard V. Crowley
Publisher : Jones & Bartlett Learning
Page : 566 pages
File Size : 46,6 Mb
Release : 2010
Category : Health & Fitness
ISBN : 9780763765910

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An Introduction to Human Disease by Leonard V. Crowley Pdf

Human Disease

Author : Maika G. Mitchell
Publisher : Academic Press
Page : 179 pages
File Size : 40,9 Mb
Release : 2018-04-16
Category : Law
ISBN : 9780128146118

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Molecular Pathology and the Dynamics of Disease by Maika G. Mitchell Pdf

Molecular Pathology and the Dynamics of Disease bridges the basic science of, and primary clinical literature on, human disease. Topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. As new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. Assimilates theoretical knowledge with practical lab work Provides a needed clinical perspective, along with research and theory Highlights the impact of basic science on the practice of medicine

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 634 pages
File Size : 52,5 Mb
Release : 2019-11-23
Category : Medical
ISBN : 9780128132586

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Essential Concepts in Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Page : 659 pages
File Size : 44,9 Mb
Release : 2009-03-10
Category : Medical
ISBN : 9780123859129

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Molecular Pathology by William B. Coleman,Gregory J. Tsongalis Pdf

Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * Exam Master® web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam * Companion Web Site – will host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * Teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * Outlines the principles and practice of molecular pathology * Explains the practice of “molecular medicine and the translational aspects of molecular pathology

Author : Reisner,Howard Reisner
Publisher : Jones & Bartlett Publishers
Page : 849 pages
File Size : 40,7 Mb
Release : 2016-08-02
Category : Medical
ISBN : 9781284050233

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Crowley's An Introduction to Human Disease by Reisner,Howard Reisner Pdf

Preceded by An introduction to human disease / Leonard V. Crowley. 9th ed. c2013.

Author : Agnes G. Loeffler,Michael N. Hart
Publisher : Jones & Bartlett Publishers
Page : 544 pages
File Size : 55,5 Mb
Release : 2014-01-06
Category : Medical
ISBN : 9781284055405

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Introduction to Human Disease (book) by Agnes G. Loeffler,Michael N. Hart Pdf

Introduction to Human Disease: Pathophysiology for Health Professionals, Sixth Edition provides a broad overview of the most common and important human diseases for students pursuing careers in the health professions. Comprehensive yet accessible, it addresses the aspects of disease epidemiology, diagnosis, and treatment that are essential to clinical practice. The Sixth Edition of this popular text has been thoroughly updated to cover the latest advances in medical knowledge and practice, especially with regard to mental health and nutritional disorders. It also includes additional clinical information on treatments for diseases. Designed to facilitate learning, this essential reference features new full-color photos and illustrations, learning objectives, and practice questions for review and assessment. Introduction to Human Disease: Pathophysiology for Health Professions, Sixth Edition will help students gain a solid foundation in disease pathology and medical terminology to help them throughout their medical education. KEY FEATURES - Provides a comprehensive introduction to the essential aspects of human disease - Covers the most common and important human diseases, including mental illnesses - Facilitates learning with chapter objectives, key terms, and practice questions - Includes more than 400 full-color illustrations, photos, and tables NEW TO THE SIXTH EDITION - New photos and illustrations - New and updated resources for instructors and students - Updated content reflects the current state of medical knowledge and practice - More clinical information, including general and specific treatments for diseases with an emphasize on common laboratory tests - Chapter 26: Infectious Diseases and Chapter 27: Immunologic Diseases are revised and now included in Section 4: Multiple Organ System Diseases - Chapters 24: Mental Illness and 30: Nutritional Disorders are revised, to bring them up-to-date with current health problems (e.g. obesity), concepts, and terminologies

Author : John E. Craighead
Publisher : Academic Press
Page : 447 pages
File Size : 50,8 Mb
Release : 2000-03-15
Category : Medical
ISBN : 9780080538488

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Pathology and Pathogenesis of Human Viral Disease by John E. Craighead Pdf

Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context of the pathogenic mechanisms involved. The author provides a comprehensive review of the older and contemporary literature, considering both the common and much rarer complications of infection. Pathology and Pathogenesis of Human Viral Disease is written from the unique perspective of the clinical pathologist. It will help clinicians and pathologists gain a better understanding of changes that occur in viral infected cells, tissues, and organs. It will also serve as a pathology source book for virologists, internists, and pediatricians. Key Features * Provides a comprehensive, worldwide perspective of viral disease pathology * Bridges the fields of pathology and virology; integrating clinical disease with cell and tissue pathology * Addresses topics from the perspective of the clinical pathologist * Illustrates unique, viral induced pathological lesions * Considers common and uncommon complications of infection

Author : Benjamin F. Trump
Publisher : Unknown
Page : 436 pages
File Size : 54,9 Mb
Release : 1983
Category : Cytopathologie
ISBN : 3437107224

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Cellular Pathobiology of Human Disease by Benjamin F. Trump Pdf

Author : David S. Strayer,Jeffrey E. Saffitz,Emanuel Rubin
Publisher : Lippincott Williams & Wilkins
Page : 1400 pages
File Size : 42,9 Mb
Release : 2019-09-09
Category : Medical
ISBN : 9781496386151

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Rubin's Pathology by David S. Strayer,Jeffrey E. Saffitz,Emanuel Rubin Pdf

With a simple approach to essential information, Rubin’s Pathology: Mechanisms of Human Disease establishes the foundation for medical training and practice and delivers the perfect balance of basic pathology and bedside perspective to confidently and efficiently equip students for clinical success. More accessible than ever, this eighth edition emphasizes the coverage students need most—disease mechanisms, integration of mechanisms into organ system pathology, and application of pathobiology to diagnostic medicine—in an approachable format with systems-based instruction techniques in mind. Comprehensively revised and updated content reflects the latest approaches to pathology from global leaders in the field and ensures a clinically relevant understanding of key pathology competencies.

Author : Jules J. Berman
Publisher : Academic Press
Page : 398 pages
File Size : 52,7 Mb
Release : 2018-01-26
Category : Business & Economics
ISBN : 9780128143940

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Precision Medicine and the Reinvention of Human Disease by Jules J. Berman Pdf

Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution. Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine. Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine. Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter. Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way. Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field.

Author : Monte Willis,Jonathon W. Homeister,James R. Stone
Publisher : Academic Press
Page : 338 pages
File Size : 50,5 Mb
Release : 2013-12-23
Category : Science
ISBN : 9780124055254

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Cellular and Molecular Pathobiology of Cardiovascular Disease by Monte Willis,Jonathon W. Homeister,James R. Stone Pdf

Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Author : Emily Reisner,Howard Reisner
Publisher : Jones & Bartlett Learning
Page : 887 pages
File Size : 47,9 Mb
Release : 2020-12-08
Category : Health & Fitness
ISBN : 9781284183832

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Crowley's An Introduction to Human Disease: Pathology and Pathophysiology Correlations by Emily Reisner,Howard Reisner Pdf

Updated to keep pace with the many changes in the field, Crowley's An Introduction to Human Disease: Pathology and Pathophysiology Correlations, Eleventh Edition provides readers with a clear, well-illustrated explanation of the structural and functional changes associated with disease, the clinical manifestations of disease, and how to determine treatment. It reflects current information on the pathenogenesis of infectious disease and how changes in the genome are expressed as disease. The first chapters of the text discuss general concepts and diseases affecting the body as a whole. Later chapters consider the various organ systems and their diseases. The Eleventh Edition includes new content on COVID-19, Zika virus, brain eating amoebas, plus mini podcasts to address difficult concepts such as cancer and the use of microscope slides. Each new print copy includes Navigate Advantage Access that unlocks a comprehensive and interactive eBook with animations, student practice activi

Author : Leonard V. Crowley
Publisher : Jones & Bartlett Publishers
Page : 573 pages
File Size : 54,6 Mb
Release : 2014
Category : Diseases
ISBN : 9781449643898

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Essentials of Human Disease by Leonard V. Crowley Pdf