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Author : Field, Simon,Guez, Ava
Publisher : UNESCO Publishing
Page : 68 pages
File Size : 45,7 Mb
Release : 2018-11-12
Category : Electronic
ISBN : 9789231002908
Author : Antonella Zannetti,Gennaro Ilardi,Wolfgang Link
Publisher : Frontiers Media SA
Page : 566 pages
File Size : 45,6 Mb
Release : 2021-09-30
Category : Medical
ISBN : 9782889714483
Author : Xu Wang,Tengchuan Jin,Christopher James Pirozzi,Xueli Zhang,Shu-Heng Jiang
Publisher : Frontiers Media SA
Page : 448 pages
File Size : 52,7 Mb
Release : 2022-03-25
Category : Medical
ISBN : 9782889747542
Author : Khiry Jones
Publisher : Unknown
Page : 128 pages
File Size : 52,7 Mb
Release : 2019-08-21
Category : Electronic
ISBN : 0464230519
A book that will help you find clarity in the midst of distraction and confusion
Author : Anonim
Publisher : BoD – Books on Demand
Page : 320 pages
File Size : 48,7 Mb
Release : 2020-04-08
Category : Medical
ISBN : 9781789853490
This book offers significant coverage on different aspects of cancer from risk factors to the mechanisms leading to tumor progression and metastasis. Although tremendous progress has been made in cancer research and treatment, cancer metastasis remains a major unmet clinical need. The life and death of many cancer patients hangs on the degree of metastasis. This book provides new perspectives for diagnosis and cancer therapy. It includes new technologies and a new basis for current cancer therapies. To guarantee the high quality of this book, important topics are included and rigorously discussed in a simple and authentic way. The book addresses important challenges governing tumor progression and metastasis and brings new responses to both diagnosis and therapy. This book is a great source of knowledge and will be useful for researchers, medical doctors, oncologists, graduate and medical students, continued medical educators, health care providers, and all individuals interested in understanding cancer and its challenges.
Author : Alan France,Ross Homel
Publisher : Routledge
Page : 393 pages
File Size : 42,8 Mb
Release : 2013-06-17
Category : Social Science
ISBN : 9781134019397
Deals with the development of prevention policies and approaches that involve intervention 'early' in the lives of children, young people and their families. This book explores evidence that has been emerging from longitudinal and developmental prevention research.
Author : Sujit Nair,Fernando De Andrés,Aarti Gokhale
Publisher : Frontiers Media SA
Page : 180 pages
File Size : 55,5 Mb
Release : 2024-01-10
Category : Science
ISBN : 9782832541852
An exciting class of regulatory small noncoding RNAs (ncRNAs) has emerged in recent years that play key role(s) in the etiology/pathogenesis and diagnosis/prognosis of various human diseases including various hematologic and solid cancers, cardiovascular diseases including stroke/atherosclerosis, diabetes, obesity, and metabolic disorders, neuropathies, neurodegeneration including Alzheimer’s Disease, Parkinson’s Disease or Multiple Sclerosis, neurological disorders including epilepsy and muscular dystrophies, liver diseases, pulmonary fibrosis, immune-mediated inflammatory disorders and inflammatory bowel disease, gastritis, autoimmune disorders including arthritis, acromegaly, chronic kidney disease, allergic rhinitis, vitiligo, osteoporosis, obstructive sleep apnea, ocular disease, periodontitis, skeletal muscle atrophy, and parasitic diseases including leishmaniasis, amongst others. These ncRNAs include primarily microRNAs (miRNAs), long noncoding RNAs (lncRNAs), circular RNAs (circRNAs), piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs), small interfering RNAs (siRNAs) or exosomal RNAs (exRNAs), etc. that modulate the expression of target genes thus potentially regulating protein expression in normal versus diseased individuals. This Research Topic recognizes the importance of and seeks to explore, ncRNAs in the diagnosis, etiology, progression, prognosis, and treatment of human disease as well as novel biomarker discovery by multi-omics technologies and other methodologies. Indeed, high-throughput technologies employing deep sequencing, proteogenomic, microarrays, and quantitative real-time PCR have begun to shed new light on the architecture of ncRNA landscapes in various diseases and key signal transduction cascades modulated by these ncRNAs in disease pathology. Epigenetic control of gene expression mediated via miRNAs, for instance, has expanded our understanding of transcriptional and post-transcriptional regulation of gene expression by critical ncRNAs in the cellular milieu. Network biology approaches including the construction of relevant ncRNA networks, ncRNA-mRNA networks, and bioinformatics for mining of ncRNAs, are gaining greater relevance in the search for ‘target hubs’ or novel biomarker(s) of disease. Delineation of ncRNA signatures by transcriptomic profiling or RNA-seq, for example, is an important milestone in furthering our knowledge of the repertoire of specific ncRNAs implicated in various diseases. Further, elucidation of the specific steps of the signaling cascades where ncRNAs exert their regulatory actions will augment our understanding of diseases. This will lead to the development of (i) a novel biomarker, or biomarker signature panel, for disease; (ii) ncRNA-based companion diagnostics for diagnosis of disease; (iii) point-of-care testing devices based on ncRNAs; (iv) newer therapeutic agents that target novel biomarkers with specificity, thereby reducing toxicity; (v) ncRNA-based prophylactic approaches of the future; and, (vi) ncRNA-based prognosis of disease.
Author : Vladimir Spiegelman,Vijayasaradhi Setaluri
Publisher : Frontiers Media SA
Page : 125 pages
File Size : 52,9 Mb
Release : 2022-02-21
Category : Medical
ISBN : 9782889744480
Author : Natasha Kyprianou
Publisher : World Scientific
Page : 230 pages
File Size : 47,6 Mb
Release : 2012
Category : Medical
ISBN : 9781848164499
This book focuses on the functional significance of targeting apoptosis for the treatment of prostate cancer. New concepts on the challenges relating to the development of resistance by androgen-independent tumors are introduced, in terms of the contribution of anoikis and cross-talk of androgens with key growth factor signaling pathways. This volume also provides insightful discussion on the exploitation of the apoptotic and angiogenic synergism towards complete eradication of prostate tumors. Last but not least, it includes reflections on the drug development challenge based on the analysis of data from existing clinical trials.
Author : Martin J. Finkelstein,Glen A. Jones
Publisher : JHU Press
Page : 313 pages
File Size : 51,5 Mb
Release : 2019-05-21
Category : Education
ISBN : 9781421428741
What makes a professor? The answer depends on where in the world you are. Winner of the CIHE Award for Significant Research on International Higher Education by the Association for the Study of Higher Education In the twenty-first century, universities worldwide have found themselves thrust into a great "brain race" as nations, both developed and developing, seek to enhance their place in the global knowledge economy. As the concept of the de-localized university—one that has radically expanded, perhaps even beyond national borders—grows, competing nations have begun reshaping aspects of their national systems to accommodate global standards and metrics. In Professorial Pathways, Martin J. Finkelstein and Glen A. Jones consider how academic careers vary in countries that are fundamentally different in their organization and dynamics. Building on 25 years of scholarship, the book confronts major questions: What can we learn from the experience of other nations as they seek to balance the seemingly contradictory imperatives of expanding access and ensuring global competitiveness? What are the implications of this rapidly changing policy environment for the health of the academic professions on which university teaching and scholarship depends? And how can we advance the comparative study of higher education and, in particular, of the academic profession? The volume brings together detailed case studies of the latest—and ever-changing—educational developments in ten countries across Europe (France, Germany, United Kingdom, Russia), Asia (China, India, Japan), North America (United States, Canada), and South America (Brazil). Essays written by respected scholars in the field identify the major structural features of national higher education systems and academic markets that directly shape academic work and careers. Professorial Pathways will be of interest to anyone who toils in the vineyards of comparative and international higher education. Contributors: Elizabeth Balbachevsky, Martin J. Finkelstein, N. Jayaram, Glen A. Jones, Barbara M. Kehm, Dan Mao, Christine Musselin, Peter Scott, Fengqiao Yan, Akiyoshi Yonezawa, Maria Yudkevich
Author : Pauline Musset,Simon Field,Benedicte Bergseng,Anthony Mann (Writer on education and employment)
Publisher : Unknown
Page : 80 pages
File Size : 40,9 Mb
Release : 2019-03-28
Category : Apprenticeship programs
ISBN : 9264313087
One of a series of studies on vocational education and training, this review assesses the vocational education and training (VET) in Estonia and provides policy recommendations. Estonia does very well in terms of student achievement on PISA, and the results from the Survey of Adult Skills (PIAAC) are also excellent. Unemployment levels are low. But despite recent reforms, VET remains relatively low status compared to general education, dropout rates are too high for comfort, and apprenticeships, despite recent efforts, fail to attract many young people. Suggested approaches to improve VET in Estonia include the expansion of work-based learning within all VET programmes and measures to increase the number of apprentices. Tackling dropout should be done by a set of complementary measures, including support in basic skills for those students lagging behind. Building pathways between VET and general education options can help improve the status of VET. More and better career guidance, especially before the key grade 9 transition point, is also needed.
Author : Anonim
Publisher : ScholarlyEditions
Page : 148 pages
File Size : 51,6 Mb
Release : 2012-12-10
Category : Medical
ISBN : 9781464971419
Colorectal Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Colorectal Cancer. The editors have built Colorectal Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Colorectal Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Colorectal Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Aslam Ejaz,Timothy M. Pawlik
Publisher : Academic Press
Page : 328 pages
File Size : 52,5 Mb
Release : 2022-06-23
Category : Computers
ISBN : 9780323985680
Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach summarizes current knowledge and provides evidenced-based practice recommendations on how to treat patients with metastatic colorectal cancer. The book presents topics such as pre-operating imaging, the use of molecular markers in treatment decisions, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. In addition, it discusses immunotherapy, targeted therapies and survivorship. This is a valuable resource for practitioners, cancer researchers, oncologists, graduate students and members of biomedical research who need to understand more about novel treatments for colorectal cancer metastasis. Summarizes contemporary data in the workup and treatment of patients with metastatic colorectal cancer Discusses novel patient-centric personalized approaches surrounding the management of such cancer types Presents evidenced-based recommendations for precision care among patients with metastatic colorectal cancer
Author : Helen Caldwell,Neil Smith
Publisher : Learning Matters
Page : 217 pages
File Size : 49,9 Mb
Release : 2016-10-18
Category : Education
ISBN : 9781473987470
Teaching primary computing without computers? The Computing curriculum is a challenge for primary school teachers. The realities of primary school resources mean limited access to computer hardware. But computing is about more than computers. Important aspects of the fundamental principles and concepts of computer science can be taught without any hardware. Children can learn to analyse problems and computational terms and apply computational thinking to solve problems without turning on a computer. This book shows you how you can teach computing through ‘unplugged’ activities. It provides lesson examples and everyday activities to help teachers and pupils explore computing concepts in a concrete way, accelerating their understanding and grasp of key ideas such as abstraction, logic, algorithms and data representation. The unplugged approach is physical and collaborative, using kinaesthetic learning to help make computing concepts more meaningful and memorable. This book will help you to elevate your teaching, and your children's learning of computing beyond the available hardware. It focuses on the building blocks of understanding required for computation thinking.
Author : Ricardo Sabates,Centre for Research on the Wider Benefits of Learning (London, England),Great Britain. Department for Education and Skills
Publisher : Unknown
Page : 5 pages
File Size : 54,5 Mb
Release : 2007
Category : Adult education
ISBN : OCLC:228438256
