Peptide Protein And Enzyme Design

Author : Anonim
Publisher : Academic Press
Page : 684 pages
File Size : 51,6 Mb
Release : 2016-08-27
Category : Medical
ISBN : 9780128054345

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Peptide, Protein and Enzyme Design by Anonim Pdf

De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction. Continues the legacy of this premier serial with quality chapters on de novo enzyme design Represents the newest volume in the Methods in Enzymology series, providing premier, quality chapters authored by leaders in the field Ideal reference for those interested in the study of enzyme design that looks at both structure and mechanism

Author : John Joseph Langone
Publisher : Gulf Professional Publishing
Page : 864 pages
File Size : 50,5 Mb
Release : 1991
Category : Antigen-antibody reactions
ISBN : 012182103X

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Molecular Design and Modeling by John Joseph Langone Pdf

Computer-based design and modeling, computational approaches, and instrumental methods for elucidating molecular mechanisms of protein folding and ligand-acceptor interactions are included in Volumes 202 and 203, as are genetic and chemical methods for the production of functional molecules including antibodies and antigens, enzymes, receptors, nucleic acids and polysaccharides, and drugs.

Author : Paul R. Carey
Publisher : Elsevier
Page : 361 pages
File Size : 40,6 Mb
Release : 1996-06-21
Category : Science
ISBN : 0080539971

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Protein Engineering and Design by Paul R. Carey Pdf

The design and production of novel peptides and proteins occupy pivotal positions in science and technology and will continue to do so in the 21st century. Protein Engineering and Design outlines the rapid advances in computer-based modeling, protein engineering, and methods needed for protein and peptide preparation and characterization. This indispensable reference lays the groundwork for understanding this multidisciplinary activity while providing an introduction for researchers and students to the field of protein design. Introduces and defines the techniques involved in protein engineering and design Provides a concise overview of key technologies involved and demonstrates their contributions to the specialized design and production of novel proteins and peptides

Author : Anonim
Publisher : Academic Press
Page : 539 pages
File Size : 46,6 Mb
Release : 2013-02-14
Category : Science
ISBN : 9780123946294

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Methods in Protein Design by Anonim Pdf

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers methods in protein design and it has chapters on such topics as protein switch engineering by domain insertion, evolution based design of proteins, and computationally designed proteins. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers methods in protein design Contains chapters with such topics as protein switch engineering by domain insertion, evolution-based design of proteins, and computationally designed proteins

Author : Ruth Hogue Angeletti
Publisher : Elsevier
Page : 378 pages
File Size : 44,5 Mb
Release : 1998-09-14
Category : Science
ISBN : 9780080539997

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Proteins by Ruth Hogue Angeletti Pdf

Proteins: Analysis and Design focuses solely on individual experimental approaches, rather than on specific classes of proteins. The book provides insight into the important issues in protein science and how one can cope with them. These include all issues which explore the detailed relationship of protein structure to function. Provides problems and technical solutions Includes posttranslational modifications Uses synthetic peptides as biological models Details mutagenesis and protein engineering Covers design of protein structure and function

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 53,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Paul Wrede,Gisbert Schneider
Publisher : Walter de Gruyter GmbH & Co KG
Page : 396 pages
File Size : 44,7 Mb
Release : 2020-10-12
Category : Science
ISBN : 9783110874242

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Concepts in Protein Engineering and Design by Paul Wrede,Gisbert Schneider Pdf

No detailed description available for "Concepts in Protein Engineering and Design".

Author : Kristian Müller,Katja Arndt
Publisher : Springer Science & Business Media
Page : 318 pages
File Size : 48,5 Mb
Release : 2007-10-26
Category : Science
ISBN : 9781597451871

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Protein Engineering Protocols by Kristian Müller,Katja Arndt Pdf

Protein engineering is a fascinating mixture of molecular biology, protein structure analysis, computation, and biochemistry, with the goal of developing useful or valuable proteins. Protein Engineering Protocols will consider the two general, but not mutually exclusive, strategies for protein engineering. The first is known as rational design, in which the scientist uses detailed knowledge of the structure and function of the protein to make desired changes. The s- ond strategy is known as directed evolution. In this case, random mutagenesis is applied to a protein, and selection or screening is used to pick out variants that have the desired qualities. By several rounds of mutation and selection, this method mimics natural evolution. An additional technique known as DNA shuffling mixes and matches pieces of successful variants to produce better results. This process mimics recombination that occurs naturally during sexual reproduction. The first section of Protein Engineering Protocols describes rational p- tein design strategies, including computational methods, the use of non-natural amino acids to expand the biological alphabet, as well as impressive examples for the generation of proteins with novel characteristics. Although procedures for the introduction of mutations have become routine, predicting and und- standing the effects of these mutations can be very challenging and requires profound knowledge of the system as well as protein structures in general.

Author : Raphael Guerois,Manuela López de la Paz
Publisher : Springer Science & Business Media
Page : 303 pages
File Size : 53,8 Mb
Release : 2008-02-04
Category : Science
ISBN : 9781597451161

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Protein Design by Raphael Guerois,Manuela López de la Paz Pdf

Protein Design: Methods and Applications presents the most up-to-date protein design and engineering strategies so that readers can undertake their own projects with a maximum chance of success. The authors present integrated computational approaches that require various degrees of computational complexity, and the major accomplishments that have been achieved in the design and structural characterization of helical peptides and proteins.

Author : G. C. Barrett,D. T. Elmore
Publisher : Cambridge University Press
Page : 246 pages
File Size : 48,7 Mb
Release : 1998-10-29
Category : Science
ISBN : 0521468272

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Amino Acids and Peptides by G. C. Barrett,D. T. Elmore Pdf

This text is suitable for advanced undergraduate and beginning graduate students in chemistry and biochemistry studying amino acids and peptides. The authors concentrate on amino acids and peptides without detailed discussions of proteins, although the book gives all the essential background chemistry, including sequence determination, synthesis and spectroscopic methods, to enable the reader to appreciate protein behaviour at the molecular level. The approach is intended to encourage the reader to cross classical boundaries, as in the later chapters on the biological roles of amino acids and the design of peptide-based drugs. For example, there is a section on the enzyme-catalysed synthesis of peptides, with suitable examples, an area often neglected in texts describing peptide synthesis. This modern text will be of value in the amino acid, peptide and protein field, to advanced undergraduates, graduate students and research workers.

Author : Channa Basava,G.M. Anantharamaiah
Publisher : Springer Science & Business Media
Page : 313 pages
File Size : 54,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461581765

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Peptides by Channa Basava,G.M. Anantharamaiah Pdf

A successful seientific career requires constant effort on the part of the seientist. If such a career is to be achieved by seientists in developing countries where the faeilities are not easily available, even more dedication is required. Dr. K. M. Sivanandaiah, having completed a successful career in the field of peptide chemistry, is such a seientist. Being weIl aware of the limited research facilities available in India, we are extraordinarily appreciative of Professor Sivanandaiah's dedication to the advancement of science. As a Professor of Chemistry and, until his retirement in 1992, the Head of the Department of Studies in Chemistry at Bangalore University, India, he not only devoted much of his time to his students, teaching basic organic chemistry, but was also able to contribute to the field of peptide chemistry. After completing 25 years of service at Central College, Bangalore, where he was admired as an outstanding teacher, Professor Sivanandaiah is still active in research. He is now Professor Emeritus and continues to contribute to the field of peptides. As former students of Professor Sivanandaiah, we felt that publishing a book containing articles related to the design, synthesis, conformation, and biological activity of peptides and written by eminent scientists in the field of peptide research would be a fitting tribute to his role in the field of bioorganic chemistry.

Author : Vibin Ramakrishnan,Kirti Patel,Ruchika Goyal
Publisher : Academic Press
Page : 297 pages
File Size : 51,7 Mb
Release : 2022-09-17
Category : Science
ISBN : 9780323985437

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De Novo Peptide Design by Vibin Ramakrishnan,Kirti Patel,Ruchika Goyal Pdf

De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry. In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents. Gives comprehensive coverage, including peptide design, modeling, synthesis and applications Presents emerging topics in the design of peptide-based therapeutics Details the latest developments in the fields of therapeutic peptides and bio-nanotechnology Considers peptide design and the tailoring of peptides to specific functions Offers computational tools and algorithms for peptide design and experimental protocols for peptide chemistry

Author : Anonim
Publisher : Elsevier
Page : 451 pages
File Size : 53,6 Mb
Release : 2000-10-19
Category : Science
ISBN : 9780080493374

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Evolutionary Approaches to Protein Design by Anonim Pdf

This is the first high-quality, comprehensive overview of the field of evolutionary protein design. Topics include new protein design strategies, the structures of laboratory-evolved proteins, the evolution of non-natural enzyme functions, and the theory of laboratory evolution.

Author : Gang Wei,Sangamesh G. Kum bar
Publisher : Woodhead Publishing
Page : 504 pages
File Size : 54,7 Mb
Release : 2020-07-28
Category : Technology & Engineering
ISBN : 9780081028513

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Artificial Protein and Peptide Nanofibers by Gang Wei,Sangamesh G. Kum bar Pdf

Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications provides comprehensive knowledge of the preparation, modification and applications of protein and peptide nanofibers. The book reviews the synthesis and strategies necessary to create protein and peptide nanofibers, such as self-assembly (including supramolecular assembly), electrospinning, template synthesis, and enzymatic synthesis. Then, the key chemical modification and molecular design methods are highlighted that can be utilized to improve the bio-functions of these synthetic fibers. Finally, fabrication methods for key applications, such as sensing, drug delivery, imaging, tissue engineering and electronic devices are reviewed. This book will be an ideal resource for those working in materials science, polymer science, chemical engineering, nanotechnology and biomedicine. Reviews key chemical modification and molecular design methods to improve the bio-functions of synthetic peptide and protein nanofibers Discusses the most important synthesis strategies, including supramolecular assembly, electrospinning, template synthesis and enzymatic synthesis Provides information on fabrication of nanofibers for key applications such as sensing, imaging, drug delivery and tissue engineering

Author : Ben M. Dunn
Publisher : John Wiley & Sons
Page : 336 pages
File Size : 46,6 Mb
Release : 2015-02-10
Category : Medical
ISBN : 9781118996416

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Peptide Chemistry and Drug Design by Ben M. Dunn Pdf

This book focuses on peptides as drugs, a growing area of pharmaceutical research and development. It helps readers solve problems of discovering, developing, producing, and delivering peptide-based drugs. • Identifies promising new areas in peptide drug discovery • Includes chapters on discovery from natural sources, metabolic modification, and drug delivery • Overviews separation methods and techniques for analysis, bond formation, and purification • Offers readers both a professional reference and a text or resource for graduate-level students