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Pericyte Biology in Different Organs

Alexander Birbrair

Author : Alexander Birbrair
Publisher : Unknown
Page : 277 pages
File Size : 53,7 Mb
Release : 2019
Category : Epithelial cells
ISBN : 303011094X

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Pericyte Biology in Different Organs by Alexander Birbrair Pdf

The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and vascular research. This volume explores pericytes' physiologic roles in different tissues, ranging from the pancreas, lungs and liver through skeletal muscle, gut, retina and more. Together with its companion volumes Pericyte Biology in Disease and Pericyte Biology - Novel Concepts, Pericyte Biology in Different Organs presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific organs.

Pericyte Biology - Novel Concepts

Alexander Birbrair

Author : Alexander Birbrair
Publisher : Springer
Page : 170 pages
File Size : 49,8 Mb
Release : 2018-12-06
Category : Science
ISBN : 9783030026011

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Pericyte Biology - Novel Concepts by Alexander Birbrair Pdf

This volume explores novel concepts of pericyte biology. The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of detailed chapters on what we know so far about the pericytes. Together with its companion volumes Pericyte Biology in Different Organs and Pericyte Biology in Disease, Pericyte Biology - Novel Concepts presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific diseases.

Biology of Pericytes – Recent Advances

Alexander Birbrair

Author : Alexander Birbrair
Publisher : Springer Nature
Page : 283 pages
File Size : 41,6 Mb
Release : 2021-04-08
Category : Science
ISBN : 9783030621292

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Biology of Pericytes – Recent Advances by Alexander Birbrair Pdf

Pericytes were originally discovered and named more than hundred years ago as contractile cells around the blood vessel endothelial cells. Due to the lack of exclusive markers, pericytes are now defined by a combination of location, morphology and gene expression. Pericytes are attracting increasing attention as important regulators during development and during normal and disturbed organ function. In recent years, remarkable progress has been made in the identification and characterization of pericytes subpopulations and their amazing functions using state-of-art techniques. These advantages facilitated identification of molecular basis of interaction between these cells with several other more well studied cell types, and revealed key signals derived from pericytes involved in homeostasis, regeneration, and disease regulation. In the last ten years, several unexpected roles of pericytes have been discovered. It has been demonstrated that pericytes from different tissues differ in their properties as well as functions. Even more, pericytes are heterogeneous also within the same organ. This book is will describe the major contributions of pericytes to different organs biology in physiological and pathological conditions. The book will teach the readers about this so special cell type that 10 years ago was almost completely forgotten, and it was associated basically only with vascular stability. Recently, it become a very hot topic to work in. Several articles in Nature, Science and Cell have been and are being currently published about this cell type. These recent works are revealing how important those cells are for before unimaginable biological processes. Thus, this book will update us on what are the most novel functions attributed to these cells. Also, will introduce to the young generation all the history about these cells from when they were discovered in different organs till where we are now in this field. So it will be a great book for both cell biology students as well as researchers that will have an update on these cells biology in different organs.

Pericyte Biology in Disease

Alexander Birbrair

Author : Alexander Birbrair
Publisher : Springer
Page : 355 pages
File Size : 53,8 Mb
Release : 2019-05-30
Category : Science
ISBN : 9783030169084

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Pericyte Biology in Disease by Alexander Birbrair Pdf

This volume explores pericytes' roles under distinct pathological conditions, ranging from tumors, ALS, Alzheimer’s disease, Multiple Sclerosis, stroke, diabetes, atherosclerosis, muscular dystrophies and more. Together with its companion volumes Pericyte Biology in Different Organs and Pericyte Biology – Novel Concepts, Pericyte Biology in Disease presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cell biology and clinicians involved with these specific diseases.

Biology of Pericytes - Recent Advances

Alexander Birbrair

Author : Alexander Birbrair
Publisher : Unknown
Page : 0 pages
File Size : 48,8 Mb
Release : 2021
Category : Electronic
ISBN : 3030621308

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Biology of Pericytes - Recent Advances by Alexander Birbrair Pdf

Pericytes were originally discovered and named more than hundred years ago as contractile cells around the blood vessel endothelial cells. Due to the lack of exclusive markers, pericytes are now defined by a combination of location, morphology and gene expression. Pericytes are attracting increasing attention as important regulators during development and during normal and disturbed organ function. In recent years, remarkable progress has been made in the identification and characterization of pericytes subpopulations and their amazing functions using state-of-art techniques. These advantages facilitated identification of molecular basis of interaction between these cells with several other more well studied cell types, and revealed key signals derived from pericytes involved in homeostasis, regeneration, and disease regulation. In the last ten years, several unexpected roles of pericytes have been discovered. It has been demonstrated that pericytes from different tissues differ in their properties as well as functions. Even more, pericytes are heterogeneous also within the same organ. This book is will describe the major contributions of pericytes to different organs biology in physiological and pathological conditions. The book will teach the readers about this so special cell type that 10 years ago was almost completely forgotten, and it was associated basically only with vascular stability. Recently, it become a very hot topic to work in. Several articles in Nature, Science and Cell have been and are being currently published about this cell type. These recent works are revealing how important those cells are for before unimaginable biological processes. Thus, this book will update us on what are the most novel functions attributed to these cells. Also, will introduce to the young generation all the history about these cells from when they were discovered in different organs till where we are now in this field. So it will be a great book for both cell biology students as well as researchers that will have an update on these cells biology in different organs.

Pericyte Biology in Different Organs

Alexander Birbrair

Author : Alexander Birbrair
Publisher : Springer
Page : 277 pages
File Size : 49,7 Mb
Release : 2019-04-01
Category : Science
ISBN : 9783030110932

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Pericyte Biology in Different Organs by Alexander Birbrair Pdf

The present book is an attempt to describe the most recent developments in the area of pericyte biology which is one of the emergent hot topics in the field of molecular and cellular biology today. Here, we present a selected collection of thirteen detailed chapters on what we know so far about pericytes in distinct organs in physiological and pathological conditions. Further, it provides an update on the most novel functions attributed to these cells and will introduce a newer generation of researchers and scientists to the importance of these cells, ranging from their discovery in different organs through current state-of-the-science. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and vascular research. This volume explores pericytes' physiologic roles in different tissues, ranging from the pancreas, lungs and liver through skeletal muscle, gut, retina and more. Together with its companion volumes Pericyte Biology in Disease and Pericyte Biology – Novel Concepts, Pericyte Biology in Different Organs presents a comprehensive update on the latest information and most novel functions attributed to pericytes. To those researchers newer to this area, it will be useful to have the background information on these cells' unique history. It will be invaluable for both advanced cell biology students as well as researchers in cell biology, stem cells and researchers or clinicians involved with specific organs.

Mechanisms of Angiogenesis

Matthias Clauss,Georg Breier

Author : Matthias Clauss,Georg Breier
Publisher : Springer Science & Business Media
Page : 342 pages
File Size : 43,6 Mb
Release : 2004-11-22
Category : Medical
ISBN : 3764364599

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Mechanisms of Angiogenesis by Matthias Clauss,Georg Breier Pdf

Is it advisable to go back from bedside to the bench? During the last decade, few topics encountered such a broad interest in bio- gy and medicine as angiogenesis. The amazing ability of the body to restore blood flow by induction of blood vessel growth as part of an adaptive process has alarmed physicians dealing with diseases in which angiogenesis is either exaggerated (as in tumors) or too slow (as in ischemic diseases of heart and brain). Not surprisingly, pro- and antiangiogenic strategies have found their way into clinical trials. For instance, for the USA, the NIH website in early 2004 displayed 38 clinical studies involving either pro- or antiangiogenic th- apies. Given the expected overwhelming wealth of clinical data, the question may be asked whether further exploration of biological mechanisms is required or whether results from the bedside are instructive enough to proceed. This question depends also on the progress of pro- and antiangiogenic clinical trials. In the following, I give a short overview about some of the progress that has been made in this field. Since Judah Folkman proposed antiangiogenic tumor therapy thirty years ago, it has become increasingly evident that agents which interfere with blood vessel formation also block tumor progression. Accordingly, antiangiogenic therapy has gained much attention as a potential adjunct to conventional c- cer therapy.

Cell Biology and Translational Medicine, Volume 1

Kursad Turksen

Author : Kursad Turksen
Publisher : Springer
Page : 168 pages
File Size : 53,7 Mb
Release : 2018-08-21
Category : Science
ISBN : 9783319938677

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Cell Biology and Translational Medicine, Volume 1 by Kursad Turksen Pdf

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. With a goal to accelerate advances by timely information exchange, this new book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series is launched. Emerging areas of regenerative medicine and translational aspects of stem cells will be covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the first volume of a continuing series.

The Cerebral Circulation

Marilyn J. Cipolla

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
Page : 82 pages
File Size : 48,5 Mb
Release : 2016-07-28
Category : Medical
ISBN : 9781615047239

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The Cerebral Circulation by Marilyn J. Cipolla Pdf

This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

The Blood Brain Barrier (BBB)

Gert Fricker,Melanie Ott,Anne Mahringer

Author : Gert Fricker,Melanie Ott,Anne Mahringer
Publisher : Springer
Page : 163 pages
File Size : 51,5 Mb
Release : 2014-10-24
Category : Science
ISBN : 9783662437872

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The Blood Brain Barrier (BBB) by Gert Fricker,Melanie Ott,Anne Mahringer Pdf

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Vascular Biology of the Placenta

Yuping Wang

Author : Yuping Wang
Publisher : Biota Publishing
Page : 126 pages
File Size : 55,6 Mb
Release : 2017-06-23
Category : Medical
ISBN : 9781615047512

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Vascular Biology of the Placenta by Yuping Wang Pdf

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Biomedical Engineering Systems and Technologies

Xuesong Ye,Filipe Soares,Elisabetta De Maria,Pedro Gómez Vilda,Federico Cabitza,Ana Fred,Hugo Gamboa

Author : Xuesong Ye,Filipe Soares,Elisabetta De Maria,Pedro Gómez Vilda,Federico Cabitza,Ana Fred,Hugo Gamboa
Publisher : Springer Nature
Page : 612 pages
File Size : 46,8 Mb
Release : 2021-03-29
Category : Medical
ISBN : 9783030723798

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Biomedical Engineering Systems and Technologies by Xuesong Ye,Filipe Soares,Elisabetta De Maria,Pedro Gómez Vilda,Federico Cabitza,Ana Fred,Hugo Gamboa Pdf

This book constitutes extended and revised versions of the selected papers from the 13th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2020, held in Valletta, Malta, in February 2020. The 29 revised and extended full papers presented were carefully reviewed and selected from a total of 363 submissions. The papers are organized in topical sections on biomedical electronics and devices; bioimaging; bioinformatics models, methods and algorithms; bio-inspired systems and signal processing; health informatic

Vascular Development

Derek J. Chadwick,Jamie A. Goode

Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 260 pages
File Size : 40,7 Mb
Release : 2007-08-20
Category : Science
ISBN : 9780470319420

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Vascular Development by Derek J. Chadwick,Jamie A. Goode Pdf

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

Adler's Physiology of the Eye

Leonard A Levin,Paul L. Kaufman,Mary Elizabeth Hartnett

Author : Leonard A Levin,Paul L. Kaufman,Mary Elizabeth Hartnett
Publisher : Elsevier Health Sciences
Page : 3076 pages
File Size : 41,5 Mb
Release : 2024-02-14
Category : Medical
ISBN : 9780323834070

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Adler's Physiology of the Eye by Leonard A Levin,Paul L. Kaufman,Mary Elizabeth Hartnett Pdf

Written and designed to enhance your understanding of ocular function, structure, and anatomy, Adler's Physiology of the Eye is a classic, best-selling text that makes critical information easier to learn and retain. The fully revised 12th Edition continues the successful Adler’s approach that connects basic science and clinical aspects in a user-friendly, highly visual format—ideal for study, review, and exam preparation. It captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. Covers the full structure and function of the eye and its related anatomy and makes the connection between physiology and clinical practice. Includes major updates throughout, including new information on OCT/OCTA imaging, new drug delivery methods, ocular biomechanics, and evolving gene therapies. Organizes content by function, rather than anatomy, to help you make a stronger connection between physiological principles and clinical practice. Explains the physiological principles that underlie visual acuity, intraocular pressure, ocular circulation, the extraocular muscles, and much more. Features approximately 1,000 illustrations throughout, including medical artwork; schematics, charts, and graphs; clinical photographs; and more. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Microvascular Research: Biology and Pathology, Two-Volume Set

David Shepro

Author : David Shepro
Publisher : Elsevier
Page : 1353 pages
File Size : 54,7 Mb
Release : 2005-11-03
Category : Medical
ISBN : 9780126395105

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Microvascular Research: Biology and Pathology, Two-Volume Set by David Shepro Pdf

The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines. This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally. * Broad coverage of both basic and clinical aspects of microvasculature research * Contains 167 chapters from over 300 international authors * Each chapter includes key figures and annotated references

Pericyte Biology In Different Organs

Pericyte Biology in Different Organs by Alexander Birbrair Pdf

Pericyte Biology - Novel Concepts by Alexander Birbrair Pdf

Biology of Pericytes – Recent Advances by Alexander Birbrair Pdf

Pericyte Biology in Disease by Alexander Birbrair Pdf

Biology of Pericytes - Recent Advances by Alexander Birbrair Pdf

Pericyte Biology in Different Organs by Alexander Birbrair Pdf

Mechanisms of Angiogenesis by Matthias Clauss,Georg Breier Pdf

Cell Biology and Translational Medicine, Volume 1 by Kursad Turksen Pdf

The Cerebral Circulation by Marilyn J. Cipolla Pdf

The Blood Brain Barrier (BBB) by Gert Fricker,Melanie Ott,Anne Mahringer Pdf

Vascular Biology of the Placenta by Yuping Wang Pdf

Biomedical Engineering Systems and Technologies by Xuesong Ye,Filipe Soares,Elisabetta De Maria,Pedro Gómez Vilda,Federico Cabitza,Ana Fred,Hugo Gamboa Pdf

Vascular Development by Derek J. Chadwick,Jamie A. Goode Pdf

Adler's Physiology of the Eye by Leonard A Levin,Paul L. Kaufman,Mary Elizabeth Hartnett Pdf

Microvascular Research: Biology and Pathology, Two-Volume Set by David Shepro Pdf

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