Peritoneal Surface Malignancies

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Peritoneal Surface Malignancies

Emel Canbay,Yutaka Yonemura
Peritoneal Surface Malignancies Book PDF

Author : Emel Canbay,Yutaka Yonemura
Publisher : Springer
Page : 109 pages
File Size : 41,6 Mb
Release : 2015-07-09
Category : Medical
ISBN : 9783319129372

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Peritoneal Surface Malignancies by Emel Canbay,Yutaka Yonemura Pdf

This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by our leader Paul H. Sugarbaker are performed to treat peritoneal metastases by surgeons all around the world. Therefore this book is focused on detailed surgical anatomy of the peritoneum, preoperative clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipments, different surgical procedures for CRS and reconstruction, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies. The chapter on molecular mechanisms of the formation of peritoneal carcinomatosis provides insight into a rapidly expanding knowledge within this speciality. This book should be valuable for surgical oncologists who deal with multimodal treatment for peritoneal surface malignancies, as well as for the trained peritonectomy surgeons. For the senior surgeons, it will also introduce new techniques and approaches in this field such as dealing with the omental cakes and massive organ involvement that requires multi-organ resection.

Treatment of Peritoneal Surface Malignancies

Angelo Di Giorgio,Enrico Pinto
Treatment of Peritoneal Surface Malignancies Book PDF

Author : Angelo Di Giorgio,Enrico Pinto
Publisher : Springer
Page : 396 pages
File Size : 53,7 Mb
Release : 2015-02-14
Category : Medical
ISBN : 9788847057111

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Treatment of Peritoneal Surface Malignancies by Angelo Di Giorgio,Enrico Pinto Pdf

This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the only available completed studies) and of ongoing and future phase 3 studies. Particular attention is paid to the results of integrated treatment comprising cytoreduction (peritonectomy) and hyperthermic intraperitoneal chemotherapy (HIPEC). Helpful background information is also included on the definition and clinical assessment of each clinical form. The book, drawing on data from the entire Italian experience as well as world literature, will be an outstanding benchmark for health professionals and researchers.

Treatment of Peritoneal Surface Malignancies, An Issue of Surgical Oncology Clinics, E-Book

Jesus Esquivel
Treatment of Peritoneal Surface Malignancies An Issue of Surgical Oncology Clinics E Book Book PDF

Author : Jesus Esquivel
Publisher : Elsevier Health Sciences
Page : 219 pages
File Size : 53,8 Mb
Release : 2012-10-30
Category : Medical
ISBN : 9781455754250

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Treatment of Peritoneal Surface Malignancies, An Issue of Surgical Oncology Clinics, E-Book by Jesus Esquivel Pdf

This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. Jesus Esquivel, will focus on the current status and future directions of the treatment of the most common peritoneal surface malignancies: appendix cancer, colorectal cancer, ovarian cancer, gastric cancer, and peritoneal mesothelioma. This issue will also outline some of the most common issues that arise regarding cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), such as pharmacokinetic rationale of heat and intraperitoneal chemotherapy, HIPEC techniques and safety considerations, how to start a peritoneal surface malignancy program, anesthesia considerations during cytoreductive surgery and HIPEC, patient selection for cytoreductive surgery and HIPEC, and the role of dystemic chemotherapy in the management of peritoneal surface malignancies of appendiceal and colorectal origin.

Management of Peritoneal Surface Malignancies. (Cytoreductive Surgery, HIPEC, PIPAC, and Beyond)

Amine Souadka,Naoual Bakrin
Management of Peritoneal Surface Malignancies Cytoreductive Surgery HIPEC PIPAC and Beyond Book PDF

Author : Amine Souadka,Naoual Bakrin
Publisher : Frontiers Media SA
Page : 130 pages
File Size : 45,5 Mb
Release : 2024-04-05
Category : Medical
ISBN : 9782832546703

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Management of Peritoneal Surface Malignancies. (Cytoreductive Surgery, HIPEC, PIPAC, and Beyond) by Amine Souadka,Naoual Bakrin Pdf

Peritoneal surface malignancies (PSM) include a heterogeneous group of primary tumors, like peritoneal mesothelioma, and peritoneal metastases from various origins such as ovarian, gastric, colorectal, or appendicular cancers. Their pathophysiology is complex and still not fully elucidated. Historically, due to their dismal prognosis, peritoneal surface malignancies were considered a terminal condition and treated as such in palliative intent.. Surgery has become pivotal in the treatment of PSM and the development of specific techniques of cytoreductive surgery (peritonectomies, “en-bloc” resection) open up a new era of curative intent treatments.

Unusual Cases in Peritoneal Surface Malignancies

Emel Canbay
Unusual Cases in Peritoneal Surface Malignancies Book PDF

Author : Emel Canbay
Publisher : Springer
Page : 141 pages
File Size : 52,5 Mb
Release : 2017-03-22
Category : Medical
ISBN : 9783319515236

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Unusual Cases in Peritoneal Surface Malignancies by Emel Canbay Pdf

This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies which have originated from different primaries, such as breast cancer, small bowel cancers and imatinib resistant GISTosis and sarcomas and pseudomyxoma. The book provides the most up-to-date information on current approaches such as cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Given the increasing evidence that the patients who may benefit from this treatment modality avoid potential lethal course of these diseases, the book explores the application of these approaches to a number of types of malignancy. The first chapters explore Benign Multicystic Mesothelioma and Pseudomyxoma Peritonei arising from unusual primaries. Among other explored topics are peritoneal metastases from serous papillary uterine carcinoma, sarcoma and from unusual origins. This book is valuable for surgical oncologists who deal with the management of peritoneal surface malignancies.

Advances in Peritoneal Surface Oncology

S. González-Moreno
Advances in Peritoneal Surface Oncology Book PDF

Author : S. González-Moreno
Publisher : Springer Science & Business Media
Page : 182 pages
File Size : 41,7 Mb
Release : 2010-05-28
Category : Medical
ISBN : 9783540307600

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Advances in Peritoneal Surface Oncology by S. González-Moreno Pdf

This book reviews current research in peritoneal malignant dissemination, from its pathogenesis and molecular mechanisms to the latest clinical trials. The book covers the essentials of perioperative intraperitoneal chemotherapy and modern histopathological assessment of peritoneal surface malignancy. The book’s historical perspective on the unfolding of new knowledge points the way for future research. Contributors include leading experts, among them the pioneers who gave birth to this new era in oncology.

Management of Peritoneal Metastases- Cytoreductive Surgery, HIPEC and Beyond

Aditi Bhatt
Management of Peritoneal Metastases Cytoreductive Surgery HIPEC and Beyond Book PDF

Author : Aditi Bhatt
Publisher : Springer
Page : 580 pages
File Size : 41,8 Mb
Release : 2018-04-02
Category : Medical
ISBN : 9789811070532

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Management of Peritoneal Metastases- Cytoreductive Surgery, HIPEC and Beyond by Aditi Bhatt Pdf

The widespread acceptance among the oncology community at large of cytoreductive surgery and HIPEC as a potentially curative treatment for peritoneal metastases has paved the way for innovative new therapies that could benefit a larger proportion of patients. Much has been and continues to be published on this subject. This book provides comprehensive reviews on the various aspects of managing peritoneal metastases. The authors highlight essential practical issues that surgical oncologists encounter in their day-to-day practice, and try to before provide evidence based answers to address them. All chapters were written and/or reviewed by leading experts in this field.

Pathology of Peritoneal Metastases

Olivier Glehen,Aditi Bhatt
Pathology of Peritoneal Metastases Book PDF

Author : Olivier Glehen,Aditi Bhatt
Publisher : Springer Nature
Page : 281 pages
File Size : 41,9 Mb
Release : 2020-04-30
Category : Medical
ISBN : 9789811537738

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Pathology of Peritoneal Metastases by Olivier Glehen,Aditi Bhatt Pdf

This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors.

A Practical Guide to Peritoneal Malignancy

Tom Cecil,John Bunni,Akash Mehta
A Practical Guide to Peritoneal Malignancy Book PDF

Author : Tom Cecil,John Bunni,Akash Mehta
Publisher : CRC Press
Page : 298 pages
File Size : 42,8 Mb
Release : 2019-11-06
Category : Medical
ISBN : 9781351024846

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A Practical Guide to Peritoneal Malignancy by Tom Cecil,John Bunni,Akash Mehta Pdf

Peritoneal malignancy is a rapidly growing field within surgical oncology. National and International treatment programmes and training curricula are being established worldwide to co-ordinate treatment and management of these challenging clinical problems. A large body of evidence now exists, but the practical implications of this evidence base remain unclear. The Peritoneal Malignancy Institute in Basingstoke, the largest centre in the world, is at the forefront of new developments and techniques. This manual combines the experience of the PMI with the latest evidence to provide a practice-oriented guide to the successful set up and running of a peritoneal malignancy unit.

Treatment of Peritoneal Surface Malignancies, an Issue of Surgical Oncology Clinics

Jesus Esquivel
Treatment of Peritoneal Surface Malignancies an Issue of Surgical Oncology Clinics Book PDF

Author : Jesus Esquivel
Publisher : Saunders
Page : 0 pages
File Size : 55,9 Mb
Release : 2012-10-05
Category : Medical
ISBN : 1455754242

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Treatment of Peritoneal Surface Malignancies, an Issue of Surgical Oncology Clinics by Jesus Esquivel Pdf

This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. Jesus Esquivel, will focus on the current status and future directions of the treatment of the most common peritoneal surface malignancies: appendix cancer, colorectal cancer, ovarian cancer, gastric cancer, and peritoneal mesothelioma. This issue will also outline some of the most common issues that arise regarding cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), such as pharmacokinetic rationale of heat and intraperitoneal chemotherapy, HIPEC techniques and safety considerations, how to start a peritoneal surface malignancy program, anesthesia considerations during cytoreductive surgery and HIPEC, patient selection for cytoreductive surgery and HIPEC, and the role of dystemic chemotherapy in the management of peritoneal surface malignancies of appendiceal and colorectal origin.

Peritoneal Carcinomatosis: Drugs and Diseases

Paul H. Sugarbaker
Peritoneal Carcinomatosis Drugs and Diseases Book PDF

Author : Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 52,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461312451

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Peritoneal Carcinomatosis: Drugs and Diseases by Paul H. Sugarbaker Pdf

Peritoneal carcinomatosis dominates the clinical picture of many patients with gastrointestinal, gynecological and urological cancers. For many of them its dev astating effects contribute directly to their death. Most clinicians consider peritoneal carcinomatosis an incurable metastatic disease and give palliative treatment, re stricted to limited surgery and systemic chemotherapy. Contrary to this view, Paul Sugarbaker and his collegues base their approach on the concept that peritoneal carcinomatosis represents regional tumor spread, similar in its impact on treatment and prognosis to that of lymph node metastases in other malignancies. This concept emphasises the value of regional tumor control, as a potentially curative measure. In this book the combination of aggressive cytoreduction and intraperitoneal chemotherapy to control peritoneal carcinomatosis is extensively explored. Basic to this approach is the observation that most cancer cells show only relative resistence against commonly available drugs, which can be overcome by a sufficient increase of drug concentrations in tumor tissue. After intraperitoneal delivery, drugs will reach high tissue concentrations in the superficial few cell layers, while plasma concentrations will remain below toxic levels. Patients with only limited residual tumor at the peritoneal surface after cytoreduction may therefore benefit from intraperitoneal chemotherapy.

Peritoneal Carcinomatosis: A Multidisciplinary Approach

wim ceelen
Peritoneal Carcinomatosis A Multidisciplinary Approach Book PDF

Author : wim ceelen
Publisher : Springer Science & Business Media
Page : 535 pages
File Size : 41,7 Mb
Release : 2007-03-06
Category : Medical
ISBN : 9780387489933

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Peritoneal Carcinomatosis: A Multidisciplinary Approach by wim ceelen Pdf

This is the first volume to provide a multidisciplinary approach to peritoneal carcinomatosis encompassing molecular mechanisms, histopathology, regional and systemic cytotoxic therapy, and surgical options. Illustrations aid the reader throughout in the many facets of this disease. The book will be of particular interest for medical, surgical and gynecological oncologists faced with the complexities of decision making in patients suffering from PC.

Treatment of Peritoneal Metastasis, An Issue of Surgical Oncology Clinics of North America, E-Book

Edward A. Levine
Treatment of Peritoneal Metastasis An Issue of Surgical Oncology Clinics of North America E Book Book PDF

Author : Edward A. Levine
Publisher : Elsevier Health Sciences
Page : 209 pages
File Size : 41,7 Mb
Release : 2018-06-30
Category : Medical
ISBN : 9780323610834

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Treatment of Peritoneal Metastasis, An Issue of Surgical Oncology Clinics of North America, E-Book by Edward A. Levine Pdf

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Edward A. Levine, is devoted to Treatment of Peritoneal Metastasis. Dr. Levine has assembled expert authors to review the following topics: History of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy; Imaging for peritoneal metastases; Patient selection for cytoreductive surgery; Pharmacodynamics and pharmacokinetics of intraperitoneal chemotherapy; Genomics and peritoneal metastases; Techniques and safety issue for intraperitoneal chemotherapy; Learning curve for cytoreductive surgery; Peritoneal metastases from gastric cancer; Peritoneal metastases from mesothelioma; Peritoneal metastases from appendiceal cancer; Peritoneal metastasis from colorectal cancer; Peritoneal metastases from ovarian cancer; Palliative care of advanced peritoneal disease; and more!

Peritoneal Carcinomatosis: Principles of Management

Paul H. Sugarbaker
Peritoneal Carcinomatosis Principles of Management Book PDF

Author : Paul H. Sugarbaker
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 49,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461312475

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Peritoneal Carcinomatosis: Principles of Management by Paul H. Sugarbaker Pdf

Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.

Peritoneal Tumors and Metastases

Beate Rau,Alfred Königsrainer,Faheez Mohamed,Paul H. Sugarbaker
Peritoneal Tumors and Metastases Book PDF

Author : Beate Rau,Alfred Königsrainer,Faheez Mohamed,Paul H. Sugarbaker
Publisher : Springer Nature
Page : 407 pages
File Size : 41,7 Mb
Release : 2021-05-13
Category : Medical
ISBN : 9783030626402

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Peritoneal Tumors and Metastases by Beate Rau,Alfred Königsrainer,Faheez Mohamed,Paul H. Sugarbaker Pdf

This book provides surgeons and oncologists with a well-founded and detailed overview of the available treatment options for peritoneal malignancy and differential selection of the appropriate forms of therapy. Systemic chemotherapy options are also considered, as are surgical cytoreduction (CRS) and all forms of intraperitoneal chemotherapy (IPC) especially hyperthermic IPC (HIPEC), and immunotherapy, including specific procedures such as PIPAC. Subsequent chapters address perioperative care, complications and recurrences, as well as psycho-oncological, palliative medical and nursing care. The process of parietal and visceral peritonectomy in the large and small intestine is additionally illustrated by three video clips accessible online. Covering a broad range of aspects, including peritoneal metastasis and intraperitoneal chemotherapy, the book offers a valuable tool for surgeons, oncologists and anesthesiologists alike.