Pharmacokinetics And Drug Interactions In The Elderly And Special Issues In Elderly African American Populations

Author : Institute of Medicine,Committee on Pharmacokinetics and Drug Interaction in the Elderly
Publisher : National Academies Press
Page : 56 pages
File Size : 54,5 Mb
Release : 1997-08-25
Category : Medical
ISBN : 9780309174527

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations by Institute of Medicine,Committee on Pharmacokinetics and Drug Interaction in the Elderly Pdf

Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.

Author : Institute of Medicine,Committee on Pharmacokinetics and Drug Interaction in the Elderly
Publisher : National Academies Press
Page : 57 pages
File Size : 50,9 Mb
Release : 1997-09-25
Category : Medical
ISBN : 9780309058926

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Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations by Institute of Medicine,Committee on Pharmacokinetics and Drug Interaction in the Elderly Pdf

Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.

Author : Concept Media, inc
Publisher : Cengage Learning
Page : 128 pages
File Size : 54,8 Mb
Release : 2006-11-14
Category : Drugs
ISBN : 1564377423

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Medication Challenges in the Elderly by Concept Media, inc Pdf

Part 1 covers absorption, metabolism and excretion of drugs, the extent of medication use by the elderly, the reasons for increased use of drugs, and the factors that increase adverse drug reactions. Part 2 discusses the pharmacokinetics and pharmacodynamics of drugs, with further explaination of the causes of adverse drug reactions in the elderly. Other topics include the underuse of medication and common drug-drug interactions.

Author : James Crooks,Ian H. Stevenson
Publisher : Unknown
Page : 304 pages
File Size : 43,9 Mb
Release : 1979
Category : Aging
ISBN : 0333238001

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Drugs and the Elderly by James Crooks,Ian H. Stevenson Pdf

Author : Stephen Jackson,Paul Jansen,Arduino Mangoni
Publisher : Wiley
Page : 552 pages
File Size : 43,9 Mb
Release : 2009-04-22
Category : Medical
ISBN : 9780470024294

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Prescribing for Elderly Patients by Stephen Jackson,Paul Jansen,Arduino Mangoni Pdf

A guide for doctors to quickly choose the right drugs in the right dose for the most important clinical problems in the elderly Prescribing medications for elderly patients is complex - this book gives clear advice on treatment regimes, drug interactions, adverse effects, and recommended dose changes Provides practical help with the problems that can arise in reaching an accurate diagnosis in the elderly, recommends clear treatment options, lists key drug interactions and side effects, and advises when to amend doses

Author : Joseph T. DiPiro
Publisher : CRC Press
Page : 958 pages
File Size : 50,9 Mb
Release : 2012-11-04
Category : Medical
ISBN : 9781351236652

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Encyclopedia of Clinical Pharmacy by Joseph T. DiPiro Pdf

The Encyclopedia of Clinical Pharmacy is a valuable resource for today's clinical pharmacist and pharmacotherapist. Over 200 researchers and practitioners provide ready access to more than 5,000 primary literature citations and hard-to-find research on: Gene therapy Health service delivery models Best practices documents Pharmaceutical software development Legal controversies, ethical issues, and court rulings Drug dosing and electronic prescription Post-marketing surveillance Generic equivalency Quality management procedures Educational and training programs Compiling expertise and recommendations from the American College of Clinical Pharmacy and the American Society of Health-System Pharmacists, the Encyclopedia unravels the increasing complexity of pharmacotherapy, the problems of medication-related morbidity and mortality, and the impact that clinically empowered pharmacists have on assuring safe and effective pharmaceutical care for patients.

Author : Anonim
Publisher : DIANE Publishing
Page : 22 pages
File Size : 46,5 Mb
Release : 2024-06-02
Category : Electronic
ISBN : 1422398293

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Prescription Drugs: FDA Guidance and Regulations Related to Data on Elderly Persons in Clinical Drug Trials by Anonim Pdf

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine
Publisher : National Academies Press
Page : 173 pages
File Size : 55,8 Mb
Release : 2007-09-11
Category : Medical
ISBN : 9780309134156

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Advancing Nuclear Medicine Through Innovation by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on State of the Science of Nuclear Medicine Pdf

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Author : Roger W. Morrell,Kim Shifren,Denise Park
Publisher : Psychology Press
Page : 376 pages
File Size : 46,7 Mb
Release : 1999-05
Category : Psychology
ISBN : 9781135680350

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Processing of Medical Information in Aging Patients by Roger W. Morrell,Kim Shifren,Denise Park Pdf

This book addresses the decision-making, adherence, and human factors issues (e.g., design of medical instructions and text) involved in medical treatment of an aging population. For gerontologists, health psychologists, and cognitive aging specialists.

Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Medical and Public Health Preparedness for Catastrophic Events,Forum on Drug Discovery, Development, and Translation
Publisher : National Academies Press
Page : 150 pages
File Size : 52,5 Mb
Release : 2011-08-27
Category : Medical
ISBN : 9780309214902

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Advancing Regulatory Science for Medical Countermeasure Development by Institute of Medicine,Board on Health Sciences Policy,Forum on Medical and Public Health Preparedness for Catastrophic Events,Forum on Drug Discovery, Development, and Translation Pdf

Whether or not the United States has safe and effective medical countermeasures-such as vaccines, drugs, and diagnostic tools-available for use during a disaster can mean the difference between life and death for many Americans. The Food and Drug Administration (FDA) and the scientific community at large could benefit from improved scientific tools and analytic techniques to undertake the complex scientific evaluation and decision making needed to make essential medical countermeasures available. At the request of FDA, the Institute of Medicine (IOM) held a workshop to examine methods to improve the development, evaluation, approval, and regulation of medical countermeasures. During public health emergencies such as influenza or chemical, biological, radiological/nuclear (CBRN) attacks, safe and effective vaccines, treatments, and other medical countermeasures are essential to protecting national security and the well being of the public. Advancing Regulatory Science for Medical Countermeasure Development examines current medical countermeasures, and investigates the future of research and development in this area. Convened on March 29-30, 2011, this workshop identified regulatory science tools and methods that are available or under development, as well as major gaps in currently available regulatory science tools. Advancing Regulatory Science for Medical Countermeasure Development is a valuable resource for federal agencies including the Food and Drug Administration (FDA), the Department of Health and Human Services (HHS), the Department of Defense (DoD), as well as health professionals, and public and private health organizations.

Author : National Research Council,Division of Behavioral and Social Sciences and Education,Center for Studies of Behavior and Development,Committee on Assessing Behavioral and Social Science Research on Aging
Publisher : National Academies Press
Page : 176 pages
File Size : 42,5 Mb
Release : 2007-02-21
Category : Social Science
ISBN : 9780309180443

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A Strategy for Assessing Science by National Research Council,Division of Behavioral and Social Sciences and Education,Center for Studies of Behavior and Development,Committee on Assessing Behavioral and Social Science Research on Aging Pdf

A Strategy for Assessing Science offers strategic advice on the perennial issue of assessing rates of progress in different scientific fields. It considers available knowledge about how science makes progress and examines a range of decision-making strategies for addressing key science policy concerns. These include avoiding undue conservatism that may arise from the influence of established disciplines; achieving rational, high-quality, accountable, and transparent decision processes; and establishing an appropriate balance of influence between scientific communities and agency science managers. A Strategy for Assessing Science identifies principles for setting priorities and specific recommendations for the context of behavioral and social research on aging.

Author : Roger Finch,Peter Davey,Mark H. Wilcox,William Irving
Publisher : OUP Oxford
Page : 409 pages
File Size : 45,5 Mb
Release : 2012-01-05
Category : Medical
ISBN : 9780191628658

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Antimicrobial Chemotherapy by Roger Finch,Peter Davey,Mark H. Wilcox,William Irving Pdf

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Author : Howard M. Fillit,Kenneth Rockwood,Kenneth Woodhouse
Publisher : Elsevier Health Sciences
Page : 1171 pages
File Size : 40,8 Mb
Release : 2010-05-10
Category : Medical
ISBN : 9781437720754

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Brocklehurst's Textbook of Geriatric Medicine and Gerontology E-Book by Howard M. Fillit,Kenneth Rockwood,Kenneth Woodhouse Pdf

Popular with generations of practitioners, Brocklehurst's Textbook of Geriatric Medicine and Gerontology has been the definitive reference of choice in the field of geriatric care. The new 7th Edition, by Howard M. Fillit, MD, Kenneth Rockwood, MD, and Kenneth Woodhouse, carries on this tradition with an increased clinical focus and updated coverage to help you meet the unique challenges posed by this growing patient population. Consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more make reference quick and easy, while over 255 illustrations compliment the text to help you find what you need on a given condition. Examples of the latest imaging studies depict the effects of aging on the brain, and new algorithms further streamline decision making. Emphasizes the clinical relevance of the latest scientific findings to help you easily apply the material to everyday practice. Features consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more that make reference quick and easy. Includes over 255 illustrations—including algorithms, photographs, and tables—that compliment the text to help you find what you need on a given condition. Provides summary boxes at the end of each chapter that highlight important points. Features the work of an expert author team, now led by Dr. Howard M. Fillit who provides an American perspective to complement the book’s traditional wealth of British expertise. Includes an expanded use of algorithms to streamline decision making. Presents more color images in the section on aging skin, offering a real-life perspective of conditions for enhanced diagnostic accuracy. Includes examples of the latest imaging studies to help you detect and classify changes to the brain during aging. Offers Grade A evidence-based references keyed to the relevant text.

Author : Joseph I. Boullata,Vincent T. Armenti
Publisher : Springer Science & Business Media
Page : 824 pages
File Size : 42,6 Mb
Release : 2010-03-17
Category : Science
ISBN : 9781603273626

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Handbook of Drug-Nutrient Interactions by Joseph I. Boullata,Vincent T. Armenti Pdf

Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care. Divided into six sections all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.

Author : Ntambwe Malangu
Publisher : BoD – Books on Demand
Page : 164 pages
File Size : 51,6 Mb
Release : 2018-05-23
Category : Medical
ISBN : 9781789231380

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Pharmacokinetics and Adverse Effects of Drugs by Ntambwe Malangu Pdf

This book is a fruit of a collaborative work from several international scientists. It will be a useful resource for researchers, students, and clinicians. Each individual chapter could serve as a prescribed reading for postgraduate students and clinicians specializing in and practicing clinical pharmacology and toxicology, pharmacotherapy and pharmacotherapeutics, pharmacovigilance, and toxicovigilance, as well as those involved in clinical research, drug discovery, and development. Every chapter in this book discusses and provides illustrations on the theme discussed based on authors' understanding and experience while summarizing existing knowledge. In doing so, each chapter provides a new insight that would benefit a novice as well as a seasoned reader in understanding the pharmacokinetic mechanisms and risk factors involved in the occurrence of adverse effects of drugs.