Pharmacology Of The Skin Ii

Author : D J Atherton
Publisher : Unknown
Page : 632 pages
File Size : 52,5 Mb
Release : 1989-08-24
Category : Electronic
ISBN : 3642740553

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Pharmacology of the Skin II by D J Atherton Pdf

The pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology, and as an important step in the development of new drugs. Detailed information which can be used as a basis for further study in this attractive field is now available for the first time. This is the second of two independent, yet complementary, volumes which form one complete work on the pharmacology of the skin. It provides academic and industrial researchers and clinicians with an integrated approach to the subject so that both the experienced worker and those new to the field can gain up-to-date insight in all the relevant topics. While Volume I covers the general pharmacology of the skin, Volume II is concerned with disease and drugs. It discusses methods of measuring the response of skin to drugs; toxicology, including drug metabolism in the skin and absorption by it; and specific drugs acting on the skin and drugs used for specific diseases. Throughout both volumes, the most recent advances on clinical pharmacological aspects of study in the field are presented.

Author : Anonim
Publisher : Springer
Page : 0 pages
File Size : 46,8 Mb
Release : 2012-02-23
Category : Medical
ISBN : 3642740561

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Pharmacology of the Skin II by Anonim Pdf

The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin as in animal models, where they may be more relevant to human physiology and disease. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of aetiology and mechanism. For example, whilst the argument continued un resolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis retinoic acid, was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on aetiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as for the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.

Author : Anonim
Publisher : Springer Science & Business Media
Page : 602 pages
File Size : 49,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642740541

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Pharmacology of the Skin II by Anonim Pdf

The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin as in animal models, where they may be more relevant to human physiology and disease. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of aetiology and mechanism. For example, whilst the argument continued un resolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis retinoic acid, was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on aetiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as for the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.

Author : Corrado L. Galli,Christopher N. Hensby,Marina Marinovich
Publisher : Springer
Page : 338 pages
File Size : 51,5 Mb
Release : 1990
Category : Medical
ISBN : UCAL:B5040149

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Skin Pharmacology and Toxicology by Corrado L. Galli,Christopher N. Hensby,Marina Marinovich Pdf

Major skin diseases, including acne, psoriasis and eczcma, affect the majority of the population at some time in their lives. In general, these diseases are physically and psychologically disfiguring for the sufferers; furthermore, by their very chronic nature skin diseases, unlike most other disease processes, present both acute and chronic therapy problems. In addition, the chronic nature of these diseases can present certain economic problems. Firstly, chronic therapy is becoming increasingly expensive and secondly, patients adhering to a strict treatment regimen will frequently be absent from their gainful employment for either medical consultation or treatment. Given that in all NATO countries the average age of the population is continually increasing, these chronic skin diseases will increase in importance in the coming years. Furthermore, as the average population age increases, additional disease processes such as skin photodamage and carcinogenicity risk becoming major areas of therapeutic concern. This book reviews in detail the major scientific areas of interest for research and clinical scientists working in skin pharmacology and toxicology. The basic principles relating to an understanding of how drugs and chemicals may influence either the skin or the body as a whole are discussed in detail by recognized international scientific experts.

Author : Stephen E. Wolverton,Jashin . Wu
Publisher : Elsevier Health Sciences
Page : 858 pages
File Size : 41,8 Mb
Release : 2019-12-14
Category : Medical
ISBN : 9780323612128

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Comprehensive Dermatologic Drug Therapy by Stephen E. Wolverton,Jashin . Wu Pdf

Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.

Author : Nancy A. Monteiro-Riviere
Publisher : CRC Press
Page : 452 pages
File Size : 50,7 Mb
Release : 2010-02-17
Category : Medical
ISBN : 9781420079180

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Toxicology of the Skin by Nancy A. Monteiro-Riviere Pdf

This key volume of the Target Organ Toxicology Series provides a fresh and modern approach to the subject of skin toxicology from the perspective of how the skin forms a barrier that protects the body from the external environment and how chemicals and drugs interact with the barrier properties of the skin. Any defects or perturbations to this barr

Author : J. Eduardo Calonje,Thomas Brenn,Alexander J Lazar,Steven D Billings
Publisher : Elsevier Health Sciences
Page : 2128 pages
File Size : 53,8 Mb
Release : 2018-10-29
Category : Medical
ISBN : 9780702075520

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McKee's Pathology of the Skin, 2 Volume Set E-Book by J. Eduardo Calonje,Thomas Brenn,Alexander J Lazar,Steven D Billings Pdf

Comprehensive and lavishly illustrated, McKee’s Pathology of the Skin, 5th Edition, is your reference of choice for up-to-date, authoritative information on dermatopathology. You’ll find clinical guidance from internationally renowned experts along with details on etiology, pathogenesis, histopathology, and differential diagnosis – making this unique reference unparalleled in its wealth of clinical and histopathological material. The 5th Edition of this classic text is a must-have resource for practicing dermatopathologists and general pathologists who sign out skin biopsies. Covers pathological aspects of skin diseases in addition to providing superb descriptions and illustrations of their clinical manifestations – the only available reference with this unique combination of features. Integrates dermatopathology, clinical correlations, and clinical photographs throughout, and features bulleted lists of clinical features and differential diagnosis tables for easy reference. Contains more than 5,000 superb histopathologic and clinical illustrations that demonstrate the range of histologic manifestations. Brings you fully up to date with key molecular aspects of disease, the capabilities and limitations of molecular diagnostics, and targeted/personalized medicine. Features up-to-date information on biologics, drug eruptions, and other developments in therapeutics. Helps you stay current with the latest diagnostic tumor markers and other new developments in immunohistochemistry. Includes a completely revised chapter on cutaneous lymphoma that reflects recent WHO-EORTC classification changes, as well as new coverage of sentinel lymph node biopsy for melanoma. Shares the knowledge of the main editor Dr. J. Eduardo Calonje, along with co-editors Thomas Brenn, and Alexander Lazar, and new co-editor Steven D. Billings who offers expertise on both dermatopathology and soft tissue tumors.

Author : William Montagna
Publisher : Unknown
Page : 0 pages
File Size : 50,5 Mb
Release : 1972
Category : Electronic
ISBN : 0125052626

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The Structure and Function of Skin by William Montagna Pdf

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 49,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : E. Carstens,Tasuku Akiyama
Publisher : CRC Press
Page : 482 pages
File Size : 41,7 Mb
Release : 2014-02-25
Category : Science
ISBN : 9781466505438

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Itch by E. Carstens,Tasuku Akiyama Pdf

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Author : Golara Honari,Rosa Andersen,Howard L. Maibach
Publisher : CRC Press
Page : 347 pages
File Size : 48,8 Mb
Release : 2017-03-31
Category : Medical
ISBN : 9781351647366

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Sensitive Skin Syndrome by Golara Honari,Rosa Andersen,Howard L. Maibach Pdf

Sensitive skin is a widely reported condition where there is subjective cutaneous hyper-reactivity to environmental factors. Progress has been made in many aspects of the background science that will help clinicians in their management of patients presenting with the condition. This new text sums up the advances in thinking on pathophysiology, classification, methods of investigation, and the different susceptibilities of different types of skin.

Author : Dirk M Elston
Publisher : CRC Press
Page : 160 pages
File Size : 44,6 Mb
Release : 2009-03-27
Category : Medical
ISBN : 9781840765144

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Infectious Diseases of the Skin by Dirk M Elston Pdf

Infections remain the leading cause of death worldwide and as new antibiotics are developed, organisms develop mechanisms of resistance. Successful treatment of skin infections relies on accurate and swift diagnosis, and visual inspection remains the most important means to that end. This book provides a pictorial guide to the diagnosis of common bacterial, fungal, and viral skin infections, as well as of arthropods of medical importance. The text is divided into chapters by class of organism, and in each chapter by clinical entity. It will be of lasting value to dermatologists and general physicians in practice and training.

Author : Jorgen Serup,Gregor B. E. Jemec,Gary L. Grove
Publisher : CRC Press
Page : 1064 pages
File Size : 42,7 Mb
Release : 2006-02-23
Category : Medical
ISBN : 9781420003307

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Handbook of Non-Invasive Methods and the Skin by Jorgen Serup,Gregor B. E. Jemec,Gary L. Grove Pdf

With contributions from prominent experts, this comprehensive handbook covers the field of non-invasive biophysical measurement methods in clinical and experimental dermatology. Structured to provide both educational and practical information, the book has proven to be of value to both young researchers and senior scientists. All coverage of major evaluation and measurement methods share a consistent format, covering scope, sources of error, application, and validity. The second edition incorporates 69 revised chapters and 95 new chapters covering topics such as computer technique, imaging techniques, skin friction, barrier functions, and more.

Author : J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publisher : Unknown
Page : 0 pages
File Size : 40,8 Mb
Release : 2013-04-25
Category : Electronic
ISBN : 1947172808

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Anatomy and Physiology by J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young Pdf

Author : Anonim
Publisher : Unknown
Page : 1440 pages
File Size : 53,7 Mb
Release : 1990
Category : Medicine
ISBN : OSU:32436011073523

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Cumulated Index Medicus by Anonim Pdf