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Physical Biology of the Cell by Rob Phillips,Jane Kondev,Julie Theriot,Hernan Garcia Pdf
Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that
Creating a Physical Biology by Phillip R. Sloan,Brandon Fogel Pdf
Despite its historical impact on the biological sciences, the paper entitled 'On the Nature of Gene Mutation and Gene Structure' has remained largely inaccessible because it was only published in a short-lived German periodical. This book makes the 'Three Man' Paper available in English for the first time.
Addresses significant problems in physical biology and adjacent disciplines. This volume provides a perspective on the methods and concepts at the heart of chemical and biological behavior, covering the topics of visualization; theory and computation for complexity; and macromolecular function, protein folding, and protein misfolding
Aspects of Physical Biology by Giancarlo Franzese,Miguel Rubi Pdf
The application to Biology of the methodologies developed in Physics is attracting an increasing interest from the scientific community. It has led to the emergence of a new interdisciplinary field, called Physical Biology, with the aim of reaching a better understanding of the biological mechanisms at molecular and cellular levels. Statistical Mechanics in particular plays an important role in the development of this new field. For this reason, the XXth session of the famous Sitges Conference on Statistical Physics was dedicated to "Physical Biology: from Molecular Interactions to Cellular Behavior". As is by now tradition, a number of lectures were subsequently selected, expanded and updated for publication as lecture notes, so as to provide both a state-of-the-art introduction and overview to a number of subjects of broader interest and to favor the interchange and cross-fertilization of ideas between biologists and physicists. The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations.
Physical Biology of Proteins and Peptides by Luis Olivares-Quiroz,Orlando Guzmán-López,Hector Eduardo Jardón-Valadez Pdf
This book covers the latest developments in the physical biology of proteins and peptides. Key insights into microscopic and macroscopic approaches to describe biologically relevant macromolecules and their interactions are provided. This book also covers a wide range of tools, including theoretical methods as statistical mechanics, normal mode analysis, kinetic theory and stochastic processes, and all-atom and coarse-grained molecular dynamics simulations. New experimental techniques are also discussed, particularly related to amiloidogenic peptides and their mutations. This is an excellent book for molecular biologists, physicists, computational scientists, and chemists. It covers cutting-edge research in this exciting, interdisciplinary research field. This book also: Discusses the latest developments in the physical biology of proteins, peptides and enzymes covering theoretical, computational, and experimental approaches Broadens readers’ understanding on the r ole of intra- and inter-molecular interactions as a fundamental cornerstone of macroscopic biological properties of macromolecules Provides a wide and useful perspective on different aspects of the physics, biology, and chemistry of proteins and peptides suitable for interdisciplinary research.
Protobiology Physical Basis Of Biology by K. Matsuno Pdf
Protobiology as a physics of becoming emphasizes the dynamics underlying conservation laws, whereas the physics of being emphasize the dynamics presupposing conservation laws. Protobiology thus concerns itself with a convoluted problem of how both the law of motion and its boundary conditions develop with time without forgetting that these two are inseparable, in contrasts to the physics of being that assumes separability.
Both a landmark text and reference book, Steven Vogel's Life in Moving Fluids has also played a catalytic role in research involving the applications of fluid mechanics to biology. In this revised edition, Vogel continues to combine humor and clear explanations as he addresses biologists and general readers interested in biological fluid mechanics, offering updates on the field over the last dozen years and expanding the coverage of the biological literature. His discussion of the relationship between fluid flow and biological design now includes sections on jet propulsion, biological pumps, swimming, blood flow, and surface waves, and on acceleration reaction and Murray's law. This edition contains an extensive bibliography for readers interested in designing their own experiments.
Physical Instrumentation in Medicine and Biology by D. J. Dewhurst Pdf
Physical Instrumentation in Medicine and Biology provides a course of study and practical assignments encompassing the basic principles of medical and biological instrumentation and common features of design and construction. The book first offers information on construction design and current, voltage, and resistance. Discussions focus on instrument design, soldering, resistors, noise in resistors, combinations of resistors, and batteries. The publication then ponders on meters, potentiometer and Wheatstone bridge, and alternating currents. The manuscript takes a look at capacitance, inductance, and transistor amplifier. Topics include condensers as used in electronic equipment, charge and discharge of condenser-resistor combination, measurement of capacitance, calculation of impedances in series, saturation, transistor output characteristic, stability, and selection of transistor types. The publication then examines valve amplifier, power supplies, regulated power supplies, and cathode ray tube. The transfer characteristics of triode, pentodes, valve amplifier, types of rectifier circuit, and filtering are discussed. The book is a valuable reference for readers interested in physical instrumentation in medicine and biology.
Cell Biology by the Numbers by Ron Milo,Rob Phillips Pdf
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Elements of Physical Biology by Alfred J Lotka Pdf
This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
The new field of physical biology fuses biology and physics. New technologies have allowed researchers to observe the inner workings of the living cell, one cell at a time. With an abundance of new data collected on individual cells, including observations of individual molecules and their interactions, researchers are developing a quantitative, physics-based understanding of life at the molecular level. They are building detailed models of how cells use molecular circuits to gather and process information, signal to each other, manage noise and variability, and adapt to their environment. This book narrows down the scope of physical biology by focusing on the microbial cell. It explores the physical phenomena of noise, feedback, and variability that arise in the cellular information-processing circuits used by bacteria. It looks at the microbe from a physics perspective, to ask how the cell optimizes its function to live within the constraints of physics. It introduces a physical and information based -- as opposed to microbiological -- perspective on communication and signaling between microbes. The book is aimed at non-expert scientists who wish to understand some of the most important emerging themes of physical biology, and to see how they help us to understand the most basic forms of life.
This book is an invitation to biologists to dust off their elementary physics and think about biological processes in Newtonian terms. In his clear, straightforward text, Colin Pennycuick demonstrates how physical laws operate at all levels, from cells to ecosystems, and shows how to applythem with precision. Rediscovering the nature of physical properties can lead to new insights and understanding.Pennycuick writes in a clear, accessible style, with many examples taken from the familiar world of zoology. One chapter deals with fractal geometry, a new way of measuring size, shape, and scale. A new feature of Pennycuick's work is the extension of the biomechanical approach to ecosystemdynamics, the subject of the last two chapters. Students of animal behaviour, ecology, and applied physics will enjoy working through the ideas in this stimulating volume.
Fundamentals of Molecular Structural Biology by Subrata Pal Pdf
Fundamentals of Molecular Structural Biology reviews the mathematical and physical foundations of molecular structural biology. Based on these fundamental concepts, it then describes molecular structure and explains basic genetic mechanisms. Given the increasingly interdisciplinary nature of research, early career researchers and those shifting into an adjacent field often require a "fundamentals" book to get them up-to-speed on the foundations of a particular field. This book fills that niche. Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease
Nonlinear and Complex Dynamics by José António Tenreiro Machado,Dumitru Baleanu,Albert C. J. Luo Pdf
Nonlinear Dynamics of Complex Systems describes chaos, fractal and stochasticities within celestial mechanics, financial systems and biochemical systems. Part I discusses methods and applications in celestial systems and new results in such areas as low energy impact dynamics, low-thrust planar trajectories to the moon and earth-to-halo transfers in the sun, earth and moon. Part II presents the dynamics of complex systems including bio-systems, neural systems, chemical systems and hydro-dynamical systems. Finally, Part III covers economic and financial systems including market uncertainty, inflation, economic activity and foreign competition and the role of nonlinear dynamics in each.