Platelets In Cardiovascular Disease

Author : Deepak L. Bhatt
Publisher : Imperial College Press
Page : 235 pages
File Size : 44,7 Mb
Release : 2008
Category : Medical
ISBN : 9781860948268

Get Book

Platelets in Cardiovascular Disease by Deepak L. Bhatt Pdf

Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine.Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease.Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful.

Author : Jawahar Mehta,Paulette Mehta
Publisher : Wiley-Blackwell
Page : 466 pages
File Size : 47,6 Mb
Release : 1981
Category : Medical
ISBN : UOM:39015002417536

Get Book

Platelets and Prostaglandins in Cardiovascular Disease by Jawahar Mehta,Paulette Mehta Pdf

Author : Charlie Graham
Publisher : Createspace Independent Publishing Platform
Page : 224 pages
File Size : 46,7 Mb
Release : 2018-03-07
Category : Electronic
ISBN : 1723461253

Get Book

Platelets in Cardiovascular Disease by Charlie Graham Pdf

The guide provides a helpful summary of the crucial part of platelets in heart medication.Cardiovascular illness is the major cause of death rate globally, and studies have found that the platelet is a vital genesis of strokes and heart stroke as well as many of the problems of angioplasty and avoid surgery treatment. A blast of knowledge of the chemistry of platelets has established their part in the development of blood clotting and, perhaps more intriguingly, their part as inflamation related tissues. This growth in information has been ique by the growth of several medication that can affect platelet action and thereby improve individual results. Indeed, several antiplatelet medication already in growth may eventually lead to noticeable developments in both the treatment and protection against cardiac arrest.Drawing upon a board of worldwide professionals, Platelets in Cardiovascular Disease provides a small yet thorough evaluation of the major improvements in antiplatelet treatment. Exercising physicians as well as those in the growth of new antithrombotic treatments will find the guide exciting and useful.

Author : A. Michael Lincoff
Publisher : Springer Science & Business Media
Page : 471 pages
File Size : 52,8 Mb
Release : 2003-03-07
Category : Medical
ISBN : 9781592593767

Get Book

Platelet Glycoprotein IIb/IIIa Inhibitors in Cardiovascular Disease by A. Michael Lincoff Pdf

This substantially revised second edition contains new chapters on the role of GPIIb/IIIa blockade during acute coronary syndromes or with fibrinolytic therapy during acute myocardial infarctions, and updated and expanded information on the latest trials of GP IIb/IIIa inhibition during percutaneous coronary intervention. Additional improvements include a new chapter on outcomes with chronic oral GP IIb/IIIa blockade following acute coronary syndromes, discussion of GPIIb/IIIa blockade with other platelet and thrombin inhibitors, and a review of the potential effects beyond inhibition of platelet aggregation.

Author : Stephen D. Wiviott
Publisher : John Wiley & Sons
Page : 312 pages
File Size : 49,5 Mb
Release : 2009-01-26
Category : Medical
ISBN : 9781444303346

Get Book

Antiplatelet Therapy In Ischemic Heart Disease by Stephen D. Wiviott Pdf

* Draws from expertise of leaders in antiplatelet therapy * Easy-to-use layout enables rapid browsing * Edited by a member of the prestigious TIMI study group withlong-standing experience in the field

Author : Paolo Gresele,Valentin Fuster,Jose A. Lopez,Clive P. Page,Jos Vermylen
Publisher : Cambridge University Press
Page : 483 pages
File Size : 45,6 Mb
Release : 2007-12-13
Category : Medical
ISBN : 9781139468763

Get Book

Platelets in Hematologic and Cardiovascular Disorders by Paolo Gresele,Valentin Fuster,Jose A. Lopez,Clive P. Page,Jos Vermylen Pdf

A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on the clinical role of platelets in a wide variety of haematologic, cardiovascular and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease. Covering platelet physiology, bleeding disorders, thrombotic disorders and antithrombotic therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take home messages have been included in each chapter to aid clinical practice. With contributions from leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well illustrated, practical resource for everyone involved in clinical practice with platelet disorders.

Author : Asim K. Duttaroy
Publisher : John Wiley & Sons
Page : 272 pages
File Size : 40,6 Mb
Release : 2018-08-27
Category : Technology & Engineering
ISBN : 9781119376057

Get Book

Nutraceuticals and Human Blood Platelet Function by Asim K. Duttaroy Pdf

A comprehensive review of the impact of dietary nutraceuticals on platelet function and its relationship to cardiovascular disease Nutraceuticals and Human Blood Platelet Function offers a summary of the most current evidence on the effects of anti-platelet factors isolated mainly from food and natural sources, their structure function relationship, bioavailability, mechanisms of actions, and also information on human trials data. The author—a noted expert in the field— explores platelet function and their roles in development of CVD, functional foods and bioactive compounds in CVD risk factors. The author highlights platelets, their mechanisms of actions, data from epidemiological studies, structure-function relationship clinical trial data, ex vivo and in vitro data. This important resource will focus primarily on human studies and emphasize functional and physiological implications of the nutritional impact on platelet function and CVD that could be an important approach to highlight the concept of preventive CVD nutrition. An authoritative text, Nutraceuticals and Human Blood Platelet Function: Offers a unique resource that connects nutrition with platelet function and its impact on cardiovascular disease Contains an evidenced-based approach, including data from human and animal clinical studies Reveals the impact of bioactive compounds and their effect on platelets Presents a text that is authored by an expert with vast experience in the field of nutrition and platelet function Written for professionals, academics, researchers, and students associated in the area of nutrition, Nutraceuticals and Human Blood Platelet Function offers a review of the most current research on the effects of platelet function and their roles in development of CVD, functional foods and bioactive compounds in CVD risk factors.

Author : Marie Lordkipanidzé,Vera Ignjatovic,Paul Jurasz
Publisher : Frontiers Media SA
Page : 226 pages
File Size : 43,6 Mb
Release : 2022-03-02
Category : Medical
ISBN : 9782889745524

Get Book

Established and Novel Roles of Platelets in Health and Disease by Marie Lordkipanidzé,Vera Ignjatovic,Paul Jurasz Pdf

Author : William K. Hass,J.Donald Easton
Publisher : Springer Science & Business Media
Page : 226 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461383062

Get Book

Ticlopidine, Platelets and Vascular Disease by William K. Hass,J.Donald Easton Pdf

Blood platelets lack a nucleus. As a result their life span is short and they cannot reproduce themselves. Platelets share these qualities with the red blood cell. Plate lets and red blood cells, nevertheless, serve vital roles in the body. One major function of the platelet is its capacity to aggregate and thereby initiate intravas cular coagulation which often underlies such major diseases as myocardial infarc tion, cerebral infarction, and pulmonary embolism. For this reason in recent years, medical attention has been directed to drugs that inhibit platelet aggregation. Aspirin was the first drug to be proven effective in this area. Since then other drugs that share aspirin's fundamental biochemical action, inhibition of platelet cyclooxygenase, have also been studied. Very recently, ticlopidine, the first of what promises to be a new class of drugs inhibiting platelet aggregation and coagulation via an entirely different biochemical mechanism, has been exten sively studied and clinically shown to be as effective or more effective than aspirin in the prevention of ischemic cardiovascular and cerebrovascular disease.

Author : Andreas Zirlik,Christoph Bode,Meinrad Gawaz
Publisher : Springer
Page : 295 pages
File Size : 43,6 Mb
Release : 2017-12-21
Category : Medical
ISBN : 9783319662244

Get Book

Platelets, Haemostasis and Inflammation by Andreas Zirlik,Christoph Bode,Meinrad Gawaz Pdf

The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.

Author : Ron Waksman,Paul A. Gurbel,Michael A. Gaglia, Jr.
Publisher : John Wiley & Sons
Page : 352 pages
File Size : 45,6 Mb
Release : 2014-03-24
Category : Medical
ISBN : 9781118494028

Get Book

Antiplatelet Therapy in Cardiovascular Disease by Ron Waksman,Paul A. Gurbel,Michael A. Gaglia, Jr. Pdf

Edited by one of the world's leading interventional cardiologistsand educators, this new book is created with an eye on giving thereader a solid, practical and clinically-focused understanding ofthis important class of drugs, from basic science to a clear-headeddiscussion of complex topics such as combination therapies,drug-drug interactions, and platelet resistance. This important new book: Begins with a concise but thorough discussion of plateletbiology and pathophysiology so that readers understand how thesetherapies work and why they can also produce such a varied range ofcomplications, from minor gastrointestinal upset, to potentiallylife-threatening conditions such as neutropenia, a criticalshortage of white blood cells. Thoroughly covers platelet function testing, including new,novel techniques. Clarifies current best-practices regarding the use ofantiplatelet agents in both chronic and acute cardiovasculardisease Reviews of all types of antiplatelet agents – fromaspirin to recently approved drugs – including indications,clinical outcomes, and side effects/complications Written by an international who's-who of experts in the field,Antiplatelet Therapy also includes an entire section covering theuse of antiplatelet drugs in PCIs, including percutaneous valverepair, which makes this text particularly essential toInterventional Cardiologists.

Author : Martin Quinn,Desmond Fitzgerald,Dermott Cox
Publisher : Springer Science & Business Media
Page : 398 pages
File Size : 55,8 Mb
Release : 2007-11-13
Category : Medical
ISBN : 9781592599172

Get Book

Platelet Function by Martin Quinn,Desmond Fitzgerald,Dermott Cox Pdf

A cutting-edge review of the latest findings on the complexities of platelet function and the various means of inhibiting platelet clot formation. The authors delineate an up-to-date picture of platelet biology and describe methods for assessing platelet function, including the commonly used platelet aggregation, thromboxane production, procoagulant function, platelet function under flow, and the expression of platelet activation markers. The focus is both on the technology and the outcome of research on platelets, including the fast developing fields of proteomics and genomics and their application to platelet research. The clinical applications of the various methods for the assessment of platelet function in vivo, as well as antiplatelet therapy, are fully discussed.

Author : Harvey J. Weiss
Publisher : Unknown
Page : 192 pages
File Size : 44,7 Mb
Release : 1982
Category : Blood platelet disorders
ISBN : UOM:39015001650970

Get Book

Platelets by Harvey J. Weiss Pdf

Author : Michael D. Sosin,Gurbir Bhatia,Gregory Y. H. Lip,Michael K. Davies
Publisher : CRC Press
Page : 144 pages
File Size : 50,7 Mb
Release : 2006-03-13
Category : Medical
ISBN : 9781840765236

Get Book

Heart Failure by Michael D. Sosin,Gurbir Bhatia,Gregory Y. H. Lip,Michael K. Davies Pdf

Using an evidence-based approach, the authors present a detailed overview of the syndrome of heart failure. They examine the causes, pathophysiology, investigation, diagnosis, and treatment (pharmacological and non-pharmacological) with emphasis on recently-published studies. Chapters focus on antiarrhythmic and antithrombotic therapy, beta blockers and inotropes, and other vasodilators such as nitrates and calcium channel blockers. The book is fully illustrated throughout with color photographs and radiographic, electrocardiogram, and echocardiogram images. It will be of interest to cardiologists and general physicians in training, general practitioners, cardiac technicians and nurses, and medical students.

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 42,7 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

Get Book

How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.